Clinical trials: Ethanol Intoxication
Alcohol Drinking, Alcohol Intoxication
Smartphone-paired Breathalyzers and Loss- and Gain-framed Texts for Reducing Drinking and Driving
This project aims to demonstrate the feasibility of a scalable behavioral intervention using smartphone-paired breathalyzers and text message aimed at reducing drinking and driving among individuals who report heavy drinking.
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcohol Impairment, Drive
- Trial name
- BESAFE (NCT03335735)
- Testing
- Loss-framed text message, Gain-Framed text message
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Alcohol Intoxication
Neurosteroids and Acute Alcohol Intoxication in Humans
1. The major aims are to assess: (1) the relationship of basal and alcohol-induced neurosteroid and GABA levels to the degree of acute alcohol intoxication in healthy male and female volunteers; and (2) the effect of acute…
- Trial name
- NCT00608686
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Alcohol Drinking, Ethanol Intoxication
Alcohol, Breast Cancer, and Metabolism
Alcohol consumption, even at low levels, has been associated with increased breast cancer risk, but the biological mechanisms underlying this relationship remain unclear.
- Conditions
- Alcohol Drinking, Ethanol Intoxication, Breastfeeding
- Trial name
- ABC-Met (NCT07779967)
- Testing
- Low-alcohol level exposure, Breast-pumping time
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcohol Consumption, Alcohol
Rapid BAC Reduction with Nutraceutical Blend Study
Study Title: Nutritional Supplement to Rapidly Decrease Blood Alcohol Concentration (BAC): Safety and Efficacy Study Design: Double-blind, randomized, placebo-controlled clinical trial Objective: Evaluate safety and efficacy of a…
- Conditions
- Alcohol Consumption, Alcohol, Hangover Symptoms, NAC, Veisalgia
- Trial name
- NCT06722898
- Testing
- Supplement
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Medical Life Care Planners, LLC
Alcohol Drinking, Alcohol Intoxication
Mindfulness-Based Intervention and Transcranial Direct Current Brain Stimulation to Reduce Heavy Drinking
Alcohol use disorder (AUD) impacts millions of Americans and is associated with significant behavioral, social, economic, medical, and neurobiological dysfunction, yet current behavioral treatments for AUD are only modestly…
- Conditions
- Alcohol Drinking, Alcohol Intoxication, Alcoholism
- Trial name
- MBItDCS (NCT02861807)
- Testing
- Brain stimulation with mindfulness-based relapse prevention
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of New Mexico
Psilocybin Intoxication
The Impact of Dose on the Impairing, Intoxicating, and Abuse-Related Effects of Psilocybin
This study will evaluate the subjective and behavioral effects of psilocybin relative to placebo and alcohol.
- Trial name
- NCT07877987
- Testing
- 0mg Psilocybin Capsule + 0.00% BAC Alcoholic Drink, 1mg Psilocybin Capsule + 0.00% BAC Alcoholic Drink, 5mg Psilocybin Capsule + 0.00% BAC Alcoholic Drink
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Binge Drinking, Heavy Drinking
Brief ROC Training Effects on Alcohol Drinking
The goal of the proposed study is to examine whether a single session of training in regulation of craving (ROC-T) affects alcohol drinking.
- Conditions
- Binge Drinking, Heavy Drinking, Young Adult, Heavy Drinker
- Trial name
- NCT03928626
- Testing
- Regulation of craving, Control (NO REGULATION)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Yale University
Stress, Physiological, Ethanol Intoxication
Internalized Stress in Relation to Alcohol Consumption
The proposed study uses an experimental design to establish causal support for the role of internalized stress, pertaining to uncertainty with regard to one's sexual orientation, in contributing to heavy drinking behavior.
- Conditions
- Stress, Physiological, Ethanol Intoxication, Distress, Emotional
- Trial name
- NCT06091189
- Testing
- Relevant Trier Social Stressor Test (TSST), Ethanol, Irrelevant Trier Social Stressor Test (TSST)
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Alcohol Drinking, Alcohol Intoxication
Breathalyzer Validation Study
The proposed project will test three commercial cellphone breathalyzers against a police grade breathalyzer device.The study will test the accuracy of these smartphone breathalyzers at assessing Breath Alcohol Content (BrAC)…
- Trial name
- BVS (NCT04086576)
- Testing
- Alcohoot, BACtrack Mobile Pro, DRIVESAFE Evoc
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Marijuana Usage, Alcohol Drinking
Neuroscience of Alcohol and Marijuana Impaired Driving
Alcohol is one of the most widely used intoxicants. The effects of driving while intoxicated are well documented, leading to the laws and regulations behind drunk driving.
- Trial name
- NCT03431987
- Testing
- One day with a dose of active THC cannabis paired with alcohol
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Hartford Hospital
Alcoholic Intoxication, Chronic
A Clinical Trial on the Efficacy of tDCS) in Reducing Alcohol Consumption in Non-abstinent Patients (REDSTIM)
The study evaluates the efficacy of 1 week of tDCS (5 sessions) placebo in reducing alcohol consumption within the 24 weeks following the treatment in non-abstinent patients with alcohol use disorders versus placebo.
- Trial name
- REDSTIM (NCT02505126)
- Testing
- Active tDCS
- Where
- France
- Volunteers
- 339 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Alcoholism, Alcohol Dependence
Interdisciplinary Study of Two Novel Anticonvulsants in Alcoholism
This is a double-blind, placebo-controlled, parallel group design study with 4 treatment groups; levetiracetam, zonisamide, topiramate, and placebo control. Subjects will receive study medications for 14 weeks.
- Conditions
- Alcoholism, Alcohol Dependence, Alcohol Abuse
- Trial name
- NCT00862563
- Testing
- Topiramate, Zonisamide, Levetiracetam
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Boston Medical Center
Alcohol Intoxication, Intimate Partner Violence (IPV)
Alcohol and Sexual Communication Among Couples in the Laboratory
Intimate Partner Sexual Violence (IPSV) is a significant and understudied public health problem among couples, yet little is known about factors that contribute to IPSV perpetration.
- Conditions
- Alcohol Intoxication, Intimate Partner Violence (IPV), Communication
- Trial name
- NCT06865872
- Testing
- Direct Communication, Indirect Communication, Alcohol (Ethanol)
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Alcoholic Intoxication
Interest of tDCS in Help for Supporting Alcohol Abstinence
The aim of the study is to evaluate in patients with alcohol disorder and forehand weaned the efficiency of 10 active tDCS sessions versus 10 sham (placebo) sessions in the support of abstinence at 3 months.
- Trial name
- ITAMAA (NCT03287154)
- Testing
- Active tDCS stimulations
- Where
- 2 sites in France
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Henri Laborit
Driving Under the Influence, Marijuana Intoxication
Cannabis Impairment Detection Application (CIDA)
Subjects will participate in a 4-visit study protocol in which they will be asked to complete a set of computerized tasks and a 45-minute simulated drive in a driving simulator.
- Conditions
- Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
- Trial name
- CIDA (NCT04230460)
- Testing
- Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Advanced Brain Monitoring, Inc.
Alcohol Use Disorders
Risk and Protective Factors of Children and Adolescents Who Were Hospitalized Due to Alcohol Intoxication
The aim of the study is to improve the prognosis of the development of alcohol consumption by considering a variety of biological, psychological and social risk and protective factors.
- Trial name
- RiScA (NCT01692054)
- Where
- Germany
- Volunteers
- 394 people
- Sponsor
- Technische Universität Dresden
Alcohol Drinking, Alcohol Use Disorder
Understanding Alcohol Reward in Social Context
In this study, the investigators examine whether emotional and social reward from alcohol varies depending on the social context of consumption.
- Conditions
- Alcohol Drinking, Alcohol Use Disorder, Alcohol Intoxication, Alcohol; Harmful Use
- Trial name
- NCT03449095
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Alcoholic Intoxication
WayToServe Español: Online Responsible Beverage Service Training for Spanish-Speaking Servers
Responsible Beverage Service Training (RBS) has been shown to be effective and recent research by this research team has shown that online RBS training (WayToServe®) was more effective, particularly over time, than usual and…
- Trial name
- WTS-E (NCT03001024)
- Testing
- Implementation of WayToServe Español, Usual and Customary RBS Training
- Where
- 2 sites in United States
- Volunteers
- 79 people
- Sponsor
- Klein Buendel, Inc.
Alcoholic Intoxication, Marijuana Abuse
Motivational Interviews for Incarcerated Teens - 1
The purpose of this study is to test the efficacy of an individual motivational interview for reducing alcohol and marijuana-related harm as well as alcohol and marijuana use in incarcerated teens.
- Trial name
- NCT00227916
- Testing
- Behavior Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Brown University
Drink Too Much, Drinking, Binge
Group-based Intervention for Club Patrons
The purpose of this study is to develop and test a group-based strategy for encouraging groups of young adults who are engaged in party behaviors at nightclubs to intervene with each other to reduce harms associated with overuse…
- Conditions
- Drink Too Much, Drinking, Binge, Drunk, Drug Use
- Trial name
- NCT03652688
- Testing
- Nightlife Safety Plans (NSP), Fire Safety
- Where
- 2 sites in United States
- Volunteers
- 959 people, healthy volunteers welcome
- Sponsor
- Pacific Institute for Research and Evaluation