Clinical trials: Ethnicity
Alzheimer Disease
BnH-015B Clinical Trial in Moderate Alzheimer's Disease
BnH-015B is a small molecule compound that targets the GluN2B binding site on NMDA receptors and positively modulates. BnH-015B has shown, through nonclinical trials, to improve symptoms of cognitive decline by regulating the…
- Trial name
- NCT06535308
- Testing
- BnH-015B 5 mg, BnH-015B 10 mg, BnH-015B 20 mg
- Where
- South Korea
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- BnH Research
Genetics
Physicians' Understanding of Human Genetic Variation
This study will develop a survey instrument to measure primary care physicians' knowledge of the variation in human genetics, their beliefs about biologic and genetic differences according to patients' race and ethnicity, and how…
- Trial name
- NCT00339924
- Where
- United States
- Volunteers
- 1,258 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Hypertension
Multi-ethnic Multi-level Strategies and Behavioral Economics to Eliminate Hypertension Disparities in Los Angeles County
The goal of the study is to promote equitable hypertension (HTN) management across the diverse patient population found in Los Angeles County Department of Health Services (LAC DHS) clinics.
- Trial name
- NCT06359691
- Testing
- Patient-focused strategies, Provider-focused strategies, Patient- and provider-focused strategies
- Where
- United States
- Volunteers
- 540 people
- Sponsor
- University of California, Los Angeles
Childhood Cancer
Study to Education Childhood Cancer Survivors About Survivorship Care
The proposed study is part of a career development award. The first two phases of research involve collaborating with adult survivors of childhood cancer representing both sexes and three ethnic/racial groups (African American…
- Trial name
- SPEAC (NCT01742481)
- Testing
- Education and empowerment
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Illinois Chicago
Prediabetes, Type 2 Diabetes
Pathobiology and Reversibility of Prediabetes in a Biracial Cohort
The reasons for the epidemics of diabetes and prediabetes, and why individuals from certain populations suffer at higher rates are not well known.
- Conditions
- Prediabetes, Type 2 Diabetes, Obesity
- Trial name
- PROP-ABC (NCT02027571)
- Testing
- Intensive Lifestyle Intervention (ILI)
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Tennessee
Social Determinants of Health, Major Depressive Disorder
The Role of Social Determinants in Cardiovascular Health and Vascular Function
This study aims to identify the influence of social determinants of health domains on vascular function in a low income, racial, and ethnic minority population at risk for disparities.
- Conditions
- Social Determinants of Health, Major Depressive Disorder, Cardiovascular Diseases
- Trial name
- CVRRC (NCT05772221)
- Testing
- Screening
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Pain, Fever
Effect of Race/Ethnicity and Genes on Acetaminophen Pharmacokinetics
Although acetaminophen is the most commonly used nonprescription drug in the USA, little is known regarding the influence of genes and race/ethnicity on acetaminophen disposition.
- Conditions
- Pain, Fever, Hepatotoxicity
- Trial name
- NCT00768716
- Testing
- Acetaminophen
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Tufts University
Hypertension, Diabetes Mellitis
Community Partnership to Examine Racial and Ethnic Differences in Health Care for Hypertension and Diabetes
Hypertension and diabetes are among the most common chronic diseases in the United States. Racial and ethnic minority groups are more at risk for these diseases than the Caucasian population.
- Trial name
- CHAMPP (NCT00379652)
- Testing
- Medical Practice Improvement, Patient Education and Support, Combination Intervention to Include Medical Practice Improvement and Patient Education and Support
- Where
- 2 sites in United States
- Volunteers
- 1,204 people
- Sponsor
- Harvard Medical School (HMS and HSDM)
Obesity, Overweight
Ethnic Dance and Screen Time Reduction to Prevent Weight Gain in Latina Girls
A randomized controlled trial to test the efficacy of an after school ethnic dance program plus a culturally-tailored, home-based screen time reduction intervention to reduce weight gain (body mass index) among lower…
- Conditions
- Obesity, Overweight, Excessive Weight Gain
- Trial name
- ECHALE (NCT00476775)
- Testing
- after school ethnic dance program - ballet folklorica, culturally-tailored, home-based screen time reduction, culturally-tailored health and nutrition education
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- Stanford University
Prostate Cancer Detection
Prostate Cancer Risk Identification in a Multi-Ethnic Cohort: a Prospective US-based Multi-center Validation Study of Proclarix
The study is a prospective, multi-center, single cohort study involving up to 10 urological clinics in the US. After provision of informed consent, up to 20 mL of whole blood will be collected from each subject.
- Trial name
- PRIME (NCT07543757)
- Testing
- Proclarix
- Where
- 7 sites in United States
- Volunteers
- 500 people
- Sponsor
- Sequenom, Inc.
Cardiovascular Diseases
Canadian Alliance for Healthy Hearts and Minds
The Cardiac, Vascular and Cognitive Dysfunction (CVCD) Alliance will be a prospective, multi-ethnic cohort study in healthy Canadian individuals between 35 and 69, looking at contextual risk factors and novel predictors of hard…
- Trial name
- NCT02220582
- Testing
- MRI
- Where
- 12 sites in Canada
- Volunteers
- 7,900 people, healthy volunteers welcome
- Sponsor
- Montreal Heart Institute
Depression in Old Age
PEERS Plus mHealth Enhanced Peer Support
The goal of this intervention study is to design and learn whether peer support that is delivered through video chats and texts can decrease depression among older adults.
- Trial name
- Peers plus (NCT05611996)
- Testing
- Peers plus
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Massachusetts General Hospital
Hypertension
Evaluating the Relationship Between Stress, Ethnicity, and Blood Pressure
High blood pressure is a common health problem among people in the United States. This study will examine the ways that stress and ethnicity play a role in the development of high blood pressure.
- Trial name
- NCT00783497
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
CABG, Ethnic Group
Outcomes of Coronary Artery Bypass Grafting in Israeli Jews and Arabs
Retrospective study of adult patients with multivessel disease undergoing isolated CABG in three centers between January 1st, 2009, and December 31st, 2023.
- Trial name
- NCT06766123
- Testing
- CABG
- Volunteers
- 7,067 people
- Sponsor
- Technion, Israel Institute of Technology
Cognitive Impairment, Vascular Diseases
11C-PIB PET Study in MESA at Columbia University
The investigators will conduct a study of brain positron emission tomography (PET) using 11C-PIB for the imaging of brain amyloid in 250 participants in the Multiethnic study of atherosclerosis (MESA) at Columbia University…
- Conditions
- Cognitive Impairment, Vascular Diseases, Alzheimer Disease, Atherosclerosis
- Trial name
- NCT03981380
- Testing
- 11C-PIB
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- José A. Luchsinger
Anxiety Disorders
Fluoxetine vs CBT in Childhood Anxiety Disorders
Treatment of every child with anxiety disorder begins with the question of which treatment to start first. Both fluoxetine and CBT have strong empirical support, but few studies have compared their initial effectiveness…
- Trial name
- SMART (NCT04760275)
- Testing
- Fluoxetine, Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 316 people
- Sponsor
- Children's Hospital Los Angeles
Healthy Volunteers
Study to Evaluate Safety, Tolerability & PK of rhNGF in Healthy Volunteers
The primary objective of this study is to assess the safety and tolerability of a single short-term and a multiple dose scheme of rhNGF when administered as eye drops in healthy subjects of Japanese ethnicity.
- Trial name
- NCT03836859
- Testing
- rhNGF 20μg/mL
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dompé Farmaceutici S.p.A
Coronary Artery Disease, Angina
Ranolazine, Ethnicity and the Metabolic Syndrome
The purpose of this study is to measure the effect of ranolazine on ETT (exercise treadmill test) exercise duration in four ethnic subgroups with established coronary artery disease and risk factor(s) for the metabolic syndrome…
- Conditions
- Coronary Artery Disease, Angina, Metabolic Syndrome
- Trial name
- REMS (NCT01304095)
- Testing
- Ranolazine
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Atlanta Heart Specialists, LLC
Healthy, Heart Disease
Family Research Study: Metabolism of Fats and Proteins in Specific Ethnic Groups
The purpose of this study is to determine whether lipoprotein(a), also called Lp(a), is a risk factor for cardiovascular (heart) disease. Lipoproteins are tiny particles that circulate in the blood.
- Trial name
- NCT00853775
- Testing
- No intervention, observational study
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
NSCLC, Healthy Volunteers
To Evaluate the Comparative Pharmacokinetics of Orally Administered EQ143 in Different Racial and Ethnic Populations
This is an open-label and uncontrolled study to evaluate the comparative PK of EQ143 following oral single dose administration in adult healthy volunteers different racial and ethnic populations.
- Conditions
- NSCLC, Healthy Volunteers, Pharmacokinetics
- Trial name
- NCT04969965
- Testing
- aumolertinib
- Where
- 2 sites in United States, New Zealand
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- EQRx, Inc.