Clinical trials: Eustachian Tube Disorder
Eustachian Tube Dysfunction
Balloon Dilation of the Eustachian Tube
In this study, patients with dysfunction of the eustachian tube will be included. They will be randomized to one of two treatment groups. 1. balloon dilation of the eustachian tube or 2.
- Trial name
- BDET (NCT05270031)
- Testing
- Balloon dilation of the eustachian tube
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Eustachian Tube Dysfunction
The Accuracy of Tests of Eustachian Tube Function
The Eustachian tube links the middle ear to the back of the nose and is designed to open to allow the pressure in the air-filled middle ear to be equal to external (atmospheric) pressure.
- Trial name
- NCT02385175
- Testing
- Different objective clinical tests of Eustachian tube function, Different patient-completed questionnaires relating to Eustachian tube dysfunction
- Where
- United Kingdom
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Barotrauma;Ear, Tympanum; Perforation
Effectiveness of Sequential Eustachian Tube Maneuvers in Hyperbaric Oxygen Conditions
Middle ear barotrauma represents the predominant complication associated with hyperbaric oxygen therapy, manifesting symptoms ranging from otalgia to tympanic membrane perforation.
- Trial name
- NCT06408363
- Testing
- Maneuver group
- Where
- Brazil
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Felicio Rocho
Eustachian Tube Dysfunction
Tubomanometry and EarPopper Devices for Eustachian Tube Function Testing
The Eustachian tube (ET) is a biological tube that links the middle ear to the back of the nose and throat. It has several functions, of which the most important is to maintain optimal middle-ear health.
- Trial name
- NCT03850197
- Testing
- EarPopper, Tympanometry, Tubomanometry
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cuneyt M. Alper
Cleft Palate
Middle Ear Pressure Disregulation in Cleft Palate Patients
The investigators know that middle-ear disease is very common in infants with cleft palate and causes hearing loss that can last into childhood.
- Trial name
- NCT00423072
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Pittsburgh
Postoperative Middle Ear Pressure, Otalgia
The Effect of Postoperative Eustachian Milking Maneuver on Eustachian Tube Dysfunction
This study will evaluate the effectiveness of this lymphatic drainage method in eliminating otalgia interruption due to eustachian dysfunction and reducing middle ear pressure, which occurs in the postoperative period after…
- Trial name
- NCT06605937
- Testing
- Eustachian milking maneuver with routine postoperative treatment protocol, Routine postoperative treatment protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Karaman Training and Research Hospital
Barotrauma;Ear, OME - Otitis Media With Effusion
Adult Study to Evaluate Placement of Tympanostomy Tubes In-office (ADEPT)
A prospective, multicenter study to evaluate effectiveness and safety of Tymbion iontophoresis and tympanostomy tube placement using the Tula iontophoresis and tube delivery systems for adults in an office setting.
- Conditions
- Barotrauma;Ear, OME - Otitis Media With Effusion, AOM - Acute Otitis Media, Eustachian Tube Dysfunction
- Trial name
- ADEPT (NCT03197558)
- Testing
- Tymbion Iontophoresis and Tube Delivery System (TDS)
- Where
- 8 sites in United States
- Volunteers
- 30 people
- Sponsor
- Tusker Medical
Patulous Eustachian Tube Dysfunction
A Trial of Clay Weight on the Ear Drum for Patulous Eustachian Tube
The Eustachian tube is a tube that connects the back of the nose with the ear. Its job is to keep the pressure on the inside of the eardrum close to the pressure outside the eardrum, so that the eardrum can vibrate properly.
- Trial name
- NCT00933478
- Testing
- Clay
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Eustachian Tube Dysfunction, Eustachian Tube Dysfunction of Left Ear
Tympanostomy Tubes Versus Eustachian Tube Dilation
The objective of this study is to determine whether tympanostomy with pressure equalization tube placement or Eustachian tube (ET) dilation is superior at reducing symptoms of patients with ET dysfunction.
- Conditions
- Eustachian Tube Dysfunction, Eustachian Tube Dysfunction of Left Ear, Eustachian Tube Dysfunction of Right Ear (Diagnosis), Eustachian Tube Dysfunction of Both Ears (Diagnosis)
- Trial name
- NCT03886740
- Testing
- Reducing symptoms of Eustachian tube dysfunction
- Sponsor
- Columbia University
Adenoidectomy, Tonsillectomy
The Evaluation of Eustachian Tube Function and Its Influencing Factors After Snoring Operation in Children
This study aims to evaluate and screen out the factors related to the improvement of eustachian tube function after adenoidectomy and/or tonsillectomy, so as to guide the treatment of children's eustachian tube function before…
- Conditions
- Adenoidectomy, Tonsillectomy, Eustachian Tube Dysfunction
- Trial name
- NCT05600595
- Testing
- Operation for snoring in children
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Eustachian Tube Dysfunction, Middle Ear Barotrauma
Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury
- Trial name
- NCT04776967
- Testing
- Hyperbaric Compression Profile
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Northwell Health
Eustachian Tube Dysfunction, Middle Ear Disease
Ph.D.-Project: Eustachian Tube Dysfunction: Causes, Diagnosis, Treatment, and Prognosis
Background: The Eustachian Tube (ET) is a mucosa-lined connection between the nasopharynx and the middle ear cavity. It is believed to have three functions: 1) ventilation of and pressure equalization in the middle ear cavity, 2)…
- Conditions
- Eustachian Tube Dysfunction, Middle Ear Disease, Hearing Loss, Conductive, Middle Ear Problem
- Trial name
- NCT05055115
- Testing
- Balloon Eustachian Tuboplasty
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Regional Hospital West Jutland
Otits Media With Effusion
Omega-3-Based Nutraceutical Supplementation as Adjunctive Therapy in Adults With Otitis Media With Effusion: A Multicenter, Double-Blind, Randomized Placebo-Controlled Trial
Brief Summary - OMENUTS Trial Otitis media with effusion (OME) is a condition in which fluid accumulates in the middle ear, causing conductive hearing loss, ear fullness, tinnitus, and Eustachian tube dysfunction.
- Trial name
- OMENUTS (NCT07721610)
- Testing
- Omega-3-based nutraceutical combination (Otoair Flogo), Bilastine 20 mg, Intranasal mometasone furoate spray
- Where
- Italy
- Volunteers
- 501 people
- Sponsor
- Isola Tiberina - Gemelli Isola Hospital, Rome, Italy
Eustachian Tube Dysfunction
XprESS ET Registry
A prospective, multicenter, registry of patients undergoing balloon dilation of the Eustachian tubes (ET).
- Trial name
- NCT04136977
- Testing
- Eustachian tube dilation
- Where
- 11 sites in United States
- Volunteers
- 169 people
- Sponsor
- Entellus Medical, Inc.
Eustachian Tube Dysfunction
Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD)
Intranasal nasal steroid sprays are the mainstay of treatment for chronic Eustachian tube dysfunction despite having little supportive evidence in the literature.
- Trial name
- NCT05275686
- Testing
- Fluticasone Propionate 93 MCG/1 ACTUATION Nasal Spray
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Ear Barotrauma, Middle Ear Disease
Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury
- Trial name
- NCT04804098
- Testing
- Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
- Where
- United States
- Volunteers
- 1,553 people
- Sponsor
- Northwell Health
Otitis Media
Eustachian Tube Growth and Development
This study is to measure over time (from 3 years until 13 years of age) Eustachian tube function (the way the Eustachian tube works) and facial growth in groups of children with two types of middle-ear disease and with little…
- Trial name
- NCT00422929
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Healthy
Gas Supply, Demand and Middle Ear Gas Balance: Specific Aim 3a Part ii
The middle ear is an airspace located behind the eardrum that consists of two connecting compartments. The compartment directly behind the eardrum is called the tympanum and contains the three small bones of the middle ear, the…
- Trial name
- NCT00494364
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Tympanic Membrane Perforation
Eustachian Tube Function and Myringoplasty/Tympanoplasty
This study will determine whether the likely success of closing a hole in the eardrum can be predicted by testing Eustachian tube function.
- Trial name
- NCT01766856
- Testing
- Eustachian tube function testing
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
Otitis Media With Effusion (OME), Eustachian Tube Dysfunction
Autoinflation as a Eustachian Tube Rehabilitation
This randomized controlled trial evaluated the effectiveness of autoinflation in preventing recurrence of otitis media with effusion (OME) and reducing the need for reoperation after tympanostomy tube (TT) extrusion in children.
- Trial name
- NCT07122999
- Testing
- Eustachi
- Where
- South Korea
- Volunteers
- 54 people
- Sponsor
- Pusan National University Hospital