Clinical trials: Euthyroid Condition
Hypothyroidism
A Study Evaluation the Safety and Efficacy of Hormone Replacement Therapy With North Star Compared to Levothyroxine in Patients With Primary Hypothyroidism
The North Star study is a multi-center, Phase 2, double-blind, randomized, parallel group clinical study to evaluate the safe and effective dose conversion from Levothyroxine to North Star therapy.
- Trial name
- NCT05712421
- Testing
- North Star, Levothyroxine
- Where
- 31 sites in United States
- Volunteers
- 303 people
- Sponsor
- Neuvosyn Laboratories, LLC
Euthyroid Sick Syndromes, Septic Shock
Thyroid Hormone Supplementation in Patients With Septic Shock
The primary aim of the study would be to determine whether there is a difference in survival in the Intensive Care Unit between the group of patients with septic shock diagnosed with euthyroid sick syndrome who were treated with…
- Trial name
- NCT05270798
- Testing
- triiodothyronine
- Where
- Bosnia and Herzegovina
- Volunteers
- 108 people
- Sponsor
- Cantonal Hospital Zenica
Child Development Disorders, Pregnancy
The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children
This study is designed to test the hypothesis that the level of the thyroid hormone thyroxine (specifically, free thyroxine, FT4) circulating in the blood of pregnant women is the key thyroid-related factor to influence early…
- Conditions
- Child Development Disorders, Pregnancy, Subclinical Hypothyroidism
- Trial name
- NCT00147433
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Acute Myocardial Infarction, Euthyroid Sick Syndrome
Effects of N-acetylcysteine on Low T3 Syndrome
The propose of this study is to determine whether N-acetylcysteine is effective in reversing the changes in thyroid hormones seen in critical illness, known as the low T3 syndrome.
- Conditions
- Acute Myocardial Infarction, Euthyroid Sick Syndrome, Ischemic Heart Disease
- Trial name
- NCT01501110
- Testing
- N-acetylcysteine
- Where
- 2 sites in Brazil
- Volunteers
- 83 people
- Sponsor
- Federal University of Rio Grande do Sul
Hyperthyroidism, Autoimmune
Preoperative Preparation With Lugol Solution in Patients With Graves-Basedow Disease.
Currently, both the American Thyroid Association and the European Thyroid Association recommend the use of Lugol Solution (LS) in the preparation of patients undergoing thyroidectomy for Graves' disease (GD), but their…
- Trial name
- LIGRADIS (NCT03980132)
- Testing
- Lugols Strong Iodine
- Where
- 21 sites in Spain
- Volunteers
- 184 people
- Sponsor
- Jesús María Villar del Moral
Thyroid Neoplasms
Comparison of the Safety and Successful Ablation of Thyroid Remnant in Post-thyroidectomized Euthyroid Patients (i.e. Patients Administered Thyrogen) Versus Hypothyroid Patients (no Thyrogen) Following 131I Administration
This study was conducted in patients with differentiated thyroid cancer who had undergone near-total thyroidectomy. After surgery patients were randomized to one of two methods of performing thyroid remnant ablation (use of…
- Trial name
- NCT00196729
- Testing
- Thyrogen + Radioiodine (131I)
- Volunteers
- 63 people
- Sponsor
- Genzyme, a Sanofi Company
Acute Respiratory Distress Syndrome, Oxidative Stress
Feeding the Critically Ill During Phases of Altered Redox Status
The FEDOX trial is a prospective randomized clinical trial exploring oxidative stress as a mechanism of harm to explain the negative outcomes found in feeding trials that achieved caloric exposure commensurate with the nationally…
- Conditions
- Acute Respiratory Distress Syndrome, Oxidative Stress, Euthyroid Sick Syndromes, Systemic Inflammatory Response Syndrome
- Trial name
- FEDOX (NCT03085615)
- Testing
- Jevity 1.5
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Illinois Chicago
Euthyroid Sick Syndromes, Non-thyroidal Illness Syndrome
Approach to a Quantitative Follow-up of Non-thyroidal Illness Syndrome
AQUA FONTIS is a unicentric, multidisciplinary, prospective cross-section and longitudinal study that aims at the development of a more clear-cut diagnostic definition and classification of non-thyroidal illness syndrome (NTIS).
- Conditions
- Euthyroid Sick Syndromes, Non-thyroidal Illness Syndrome, Low T3 Syndrome, TACITUS
- Trial name
- AQUA FONTIS (NCT00591032)
- Where
- 6 sites in Germany
- Volunteers
- 590 people
- Sponsor
- Ruhr University of Bochum
Graves' Disease
Thyroid Disease and Personality Study
Observe the relationship between thyroid function and personality traits
- Trial name
- TPS (NCT02620085)
- Testing
- blood sampling
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
Thyroid Diseases
An Assessment of Aspirin Plus Prednisone Treatment for Euthyroid Women With Thyroid Autoimmunity
Thyroid autoimmunity(TAI) per se have adverse effect on pregnancy outcomes，and aspirin and prednisone were used frequently in antithyroid antibodies(ATA) positive infertile women in clinical practice, but the impact of these…
- Trial name
- NCT04943146
- Testing
- Prednisone 10 MG+aspirin 100MG
- Where
- 2 sites in China
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Graves Disease, Amiodarone-Induced Thyrotoxicosis
Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis
The goal of this observational study is to learn about the potential differences in morbidity of thyroidectomy (removal of the thyroid gland) depending on the preoperative hormonal status.
- Conditions
- Graves Disease, Amiodarone-Induced Thyrotoxicosis, Thyroidectomy
- Trial name
- GRATES (NCT06963203)
- Where
- 15 sites in Belgium, France and 3 more
- Volunteers
- 486 people
- Sponsor
- Andrea Goldmann
Benign Thyroid Disease
Harmonic FOCUS Versus Conventional Technique in Total Thyroidectomy for Benign Thyroid Disease
New haemostatic techniques have been developed with the advent of laparoscopic surgery. Among other things, ultrasound instruments have been used for the dissection, division and coagulation of vessels and other tissue.
- Trial name
- NCT00666315
- Where
- 2 sites in Belgium, Italy
- Volunteers
- 80 people
- Sponsor
- Ethicon Endo-Surgery (Europe) GmbH
Heart Failure, Hormone Deficiencies
Hormone Deficiency in Heart Failure With Preserved Ejection Fraction
The objective of this study is to describe the prevalence of Multiple Hormone Deficiencies in Heart Failure with preserved Ejection Fraction.
- Trial name
- MHDS in HFpEF (NCT02976350)
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- Federico II University
Obesity, Euthyroid Condition
the Association Between Thyroid Hormones and Metabolic Components in Patients With Obesity
This study collected clinical data of obese patients with euthyroid function, including age, gender, height, weight, BMI, waist circumference, blood pressure, fasting blood sugar, blood sugar 2 hours after sugar load, fasting…
- Conditions
- Obesity, Euthyroid Condition, Metabolic Syndrome
- Trial name
- NCT04599374
- Testing
- no intervention
- Volunteers
- 373 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Heart Failure With Reduced Ejection Fraction (HFrEF), Low T3 Syndrome
Developing Oral LT3 Therapy for Heart Failure - HFrEF
Investigation of the safety, feasibility, and preliminary efficacy of thyroid hormone therapy with Liothyronine (LT3) in individuals with heart failure with reduced ejection fraction (HFrEF) and low triiodothyronine (T3) syndrome…
- Trial name
- DOT3HF-HFrEF (NCT04112316)
- Testing
- Liothyronine
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Pennsylvania
Pregnancy, Infertility
Selenium Supplementation in Pregnancy
Serum levels of isolated anti-thyroperoxidase (TPOab) and anti-thyreoglobulin (Tgab) autoantibodies are strongly associated with an increased risk of miscarriage and premature deliveries in euthyroid pregnant women.
- Conditions
- Pregnancy, Infertility, Auto-immune Thyroiditis
- Trial name
- Serena (NCT01465867)
- Testing
- Selenium, Selenium + L-Thyroxine (LT4)
- Where
- 11 sites in Italy
- Volunteers
- 56 people
- Sponsor
- University of Roma La Sapienza
Cardiogenic Shock, Euthyroid Sick Syndrome
Factors Influencing Outcomes in ECMO and Impella Patients: Metabolic and Thyroid Hormone Dynamics
This prospective, single-center, consecutive observational study evaluates clinical, metabolic, and endocrine factors influencing survival and clinical outcomes in adult patients undergoing temporary mechanical circulatory…
- Conditions
- Cardiogenic Shock, Euthyroid Sick Syndrome, Critical Illness
- Trial name
- NCT07885618
- Where
- Hungary
- Volunteers
- 160 people
- Sponsor
- Gottsegen National Cardiovascular Institute
Euthyroid Sick Syndrome
Levothyroxine for Children With Euthyroid Sick Syndrome
The purpose of this study is to determine whether levothyroxine is effective and safe in the treatment of children with euthyroid sick syndrome, hospitalized in a pediatric intensive care unit.
- Trial name
- NCT01631305
- Testing
- Levothyroxine, Calcium magnesia
- Where
- Mexico
- Volunteers
- 80 people
- Sponsor
- Sinaloa Pediatric Hospital
Hypothyroidism, Thyroid Disease
A Study of Armour® Thyroid Compared to Synthetic T4 (Levothyroxine) in Previously Hypothyroid Participants
This study will evaluate the safe and effective dose conversion from levothyroxine (synthetic T4) therapy to Armour Thyroid therapy in participants who are on a stable dose of levothyroxine and have thyroid stimulating hormone…
- Conditions
- Hypothyroidism, Thyroid Disease, Euthyroid, Thyroid Gland
- Trial name
- NCT04124705
- Testing
- Armour® Thyroid, Levothyroxine
- Where
- 28 sites in United States
- Volunteers
- 284 people
- Sponsor
- Allergan
Thyroid Carcinoma, Thyroid Papillary Carcinoma
Malignancy Predictors, Bethesda and TI-RADS Scores Correlated With Final Histopathology in Thyroid Diseases
In the last decades, thyroid cancer incidence has continuously increased all over the world, almost exclusively due to a sharp rise in the incidence of the papillary histologic subtype, which has the highest incidence of…
- Conditions
- Thyroid Carcinoma, Thyroid Papillary Carcinoma, Multinodular Goiter, Adolescent, Solitary Thyroid Nodule
- Trial name
- NCT04411290
- Testing
- Total thyroidectomy (TT)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital