Clinical trials: Evaluation Studies, active
MRI in Evaluation of Fecal Incontinence
Fecal Incontinence (FI) is a Debilitating Physical and Psychological Disorder Characterizedbytheinvoluntary Loss of Flatus or Liquid/Solid Stool.
Fecal incontinence (FI) is a debilitating physical and psychological disorder characterizedbytheinvoluntary loss of flatus or liquid/solid stool.
- Trial name
- NCT07898748
- Testing
- 3DendoanalultrasoundversusexternalphasedarrayMRI inevaluationoffecal Incontinence
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Assiut University
MTA, Pulp Caping
Clinical and Radiographic Evaluation of Dia-Root Bio MTA for Indirect Pulp Capping in Young Permanent Molars
This split-mouth randomized controlled clinical trial evaluates and compares the clinical and radiographic success of Dia-Root Bio MTA versus conventional Mineral Trioxide Aggregate (MTA Plus) as indirect pulp capping (IPC)…
- Conditions
- MTA, Pulp Caping, Permanent Molars, Radiographic Evaluation
- Trial name
- NCT07894523
- Testing
- Dia-Root Bio MTA Indirect Pulp Capping, MTA Plus Indirect Pulp Capping
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Tanta University
Evaluation of BDSF in FNF
BDSF Vs DHS With Anterotational Screw in Vertical FNF
Pauwels type III femoral neck fractures in young adults commonly result from high-energy trauma and are characterized by a vertical fracture orientation with substantial shear and rotational forces.
- Trial name
- RCT (NCT07896031)
- Testing
- Dynamic Hip Screw with Anterotation Screw Fixation, Biplane Double-Supported Screw Fixation
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Evaluation of Isolated Stoppa Approach in BC Fracture Acetabulum
Stoppa Approach Vs Anterior & Posterior Fixation in Management of BC Fracture Acetabulum
Double-column acetabular fractures are complex injuries that require stable anatomical reduction and fixation to restore hip function.
- Trial name
- RCT (NCT07896044)
- Testing
- Sequential anterior and posterior approaches for double column acetabular fractures, Isolated Modified Stoppa approach for management of double column acetabular fractures
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Physical Therapy Evaluation
Analysis of a Stepped-Wedge Implementation of the PT-PENCIL Tool
Despite the need to evolve, the fact that physical therapists are a constrained resource prompts the need for care prioritization that is optimally targeted.
- Trial name
- PT-PENCIL Tool (NCT05964205)
- Testing
- Electronic clinical decision support tool
- Where
- United States
- Volunteers
- 9,704 people
- Sponsor
- Brittany Lapin
Evaluation of QTc Interval
QT Interval Effects Study of Oral FXS5626 Tablets
The purpose of this study is to evaluate the Exposure-Response Relationship Between the Plasma Drug Concentrations and the Change From Baseline in QTc interval of a single oral dose of FXS5626 in healthy subjects.
- Trial name
- NCT07695779
- Testing
- FXS5626 tablet
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.
Ultrasonography, Difficult Airway
Airway Ultrasound vs Clinical Predictors for Difficult Airway
This prospective observational study aims to evaluate the diagnostic value of airway ultrasonography in predicting difficult intubation in adult patients undergoing elective surgery under general anesthesia.
- Conditions
- Ultrasonography, Difficult Airway, Preoperative Evaluation
- Trial name
- NCT07243106
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Evaluation of Postoperative Pain and Antimicrobial Efficacy
Evaluation of Postoperative Pain and the Antimicrobial Effect of Super Oxidized Water (Microcyn) and Chlorhexidine When Compared With Sodium Hypochlorite in Teeth With Asymptomatic Necrotic Pulps. A Randomized Clinical Trial
The objective of this study is to evaluate the postoperative pain and antimicrobial efficacy when using super-oxidized water (Microcyn) and 2% Chlorhexidine as irrigating solutions in comparison to 2.5% Sodium hypochlorite in…
- Trial name
- NRS (NCT07852260)
- Testing
- super-oxidized water (Microcyn) irrigating solution, 2% chlorhexidine irrigating solution, 2.5% sodium hypochlorite
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Cairo University
Head and Neck Cancer (H&N), Free Tissue Flaps
Comparing Intraoperative Indocyanine Green Fluorescence Imaging With Standard Clinical Assessment for Flap Perfusion in Head and Neck Reconstruction (VISION Trial)
This is a prospective multicentre randomised controlled trial evaluating whether intraoperative indocyanine green (ICG) fluorescence angiography improves outcomes in head and neck free flap reconstruction compared with standard…
- Conditions
- Head and Neck Cancer (H&N), Free Tissue Flaps, Free Flap, Free Flap Evaluation
- Trial name
- VISION (NCT07635420)
- Testing
- Indocyanine Green, Standard clinical perfusion assessment
- Where
- Sweden
- Volunteers
- 244 people
- Sponsor
- Region Skane
Ultrasonographic Evaluation of Epidural Depth in Infants
Evaluation of Skin-to-Epidural Distance at Different Vertebral Levels by Ultrasonography in Infants: A Prospective Observational Study
The goal of this observational study is to learn about the distance between the skin and the epidural space in infants younger than 12 months.
- Trial name
- NCT07847762
- Testing
- Ultrasonographic Assessment of Skin-to-Epidural Distance, Epidural Catheter Placement for Clinical Indications
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University - Cerrahpasa
Physical and Psychological Evaluation of Hormonal Therapy in Transsexual Persons
A European Network for the Investigation of Gender Incongruence
The physical and psychological effects of the hormonal treatment of transsexual persons are not sufficiently described. 'Transparency' wants to answer this question in a prospective manner, in a multicenter study to describe…
- Trial name
- ENIGI (NCT01072825)
- Testing
- questionnaires, blood sampling, clinical evaluation
- Where
- 4 sites in Belgium, Italy and 2 more
- Volunteers
- 125 people
- Sponsor
- University Hospital, Ghent
Dementia, Dementia, Vascular
Promoting Goals-of-Care Discussions for Patients With Memory Problems and Their Caregivers
The goal of this clinical trial is to improve communication among clinicians, patients with memory problems, and their family members.
- Conditions
- Dementia, Dementia, Vascular, Mixed Dementias, Alzheimer Disease
- Trial name
- PICSI-M (NCT05596760)
- Testing
- Jumpstart Guide
- Where
- 3 sites in United States
- Volunteers
- 1,802 people
- Sponsor
- University of Washington
Healthy Volunteers, Imaging Evaluation
Multimodal Cardiovascular and Hepatic Population Imaging
Medical imaging is increasingly important for understanding diseases, detecting them early, and personalizing treatments. New imaging techniques, which can measure processes in the body without surgery, are opening the door to a…
- Trial name
- ICONIC (NCT06906042)
- Testing
- Imaging examinations, Paramedical examinations, Medical examination
- Where
- France
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Evaluation of Microbial Colonization Around Implants and Overdenture Surfaces Using MK1 and Clip Attachments
Microbial Evaluation of MK1 and Clip Attachments in Implant Overdentures
This crossover clinical trial aims to compare the microbial colonization associated with double-structure bar implant-supported mandibular overdentures retained by either MK1 or conventional clip attachments.
- Trial name
- NCT07817498
- Testing
- MK1 Attachment System, Bar-Clip Attachment System
- Where
- Egypt
- Volunteers
- 7 people
- Sponsor
- Mansoura University
Behavior Change Interventions, Evaluation
Clinician Motivational Interviewing Training Evaluation
The goal of this study is to evaluate the impact of motivational interviewing (MI) training for Geisinger clinicians on their patients' health outcomes.
- Conditions
- Behavior Change Interventions, Evaluation, Training Effectiveness, Health Services Research
- Trial name
- NCT07814521
- Testing
- MI training
- Where
- United States
- Volunteers
- 180,000 people
- Sponsor
- Geisinger Clinic
Adolescent, Pediatric Obesity
Controlled Evaluation of an Exercise Program for Overweight Adolescents
Physical activity decreases as young people get older, especially during the shift from early to late adolescence. Unfortunately, around 81% of school-aged children worldwide between the ages of 11 and 17 do not meet the…
- Conditions
- Adolescent, Pediatric Obesity, Exercise Therapy, Health Promotion
- Trial name
- Now! (NCT06923865)
- Testing
- training group
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- University Hospital, Basel, Switzerland
Dengue Vaccination Strategy Evaluation, Transmission Modeling of Dengue
Understanding the Public Impact on Dengue Vaccination Strategies in Yunnan Province, China: A Dynamic Transmission Modeling Study
This study is a collaboration between the School of Public Health at Fudan University and the Xishuangbanna Center for Disease Control and Prevention in Yunnan Province, China.
- Conditions
- Dengue Vaccination Strategy Evaluation, Transmission Modeling of Dengue, Public Health Impact of Vaccination
- Trial name
- NCT07206784
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Fudan University
Evaluation of Mainstreamed Models of Genetic Service Delivery, Genetic Disease
Implementation-effectiveness Trial of Mainstreaming of Clinical Genomic Sequencing for Rare Disease in Ontario, Canada
Genomic sequencing (GS) is increasingly recommended as a diagnostic test for patients with suspected genetic disorders, but access often remains limited to those referred to medical geneticists.
- Conditions
- Evaluation of Mainstreamed Models of Genetic Service Delivery, Genetic Disease, Neurodevelomental Disorders
- Trial name
- NCT07799792
- Testing
- Genome-wide Sequencing Ordering
- Volunteers
- 100 people
- Sponsor
- The Hospital for Sick Children
Cystic Fibrosis (CF), Cardiovascular (CV) Risk
Heart and Blood Vessels Health in People With Cystic Fibrosis
Cystic fibrosis (CF) is a disease that affects over 11,000 people in the UK. It is a genetic condition that affects many organs including the lungs, pancreas, kidneys and liver.
- Conditions
- Cystic Fibrosis (CF), Cardiovascular (CV) Risk, Flow-mediated Dilation Evaluation of the Brachial Artery, Pulse Wave Analysis
- Trial name
- CHi-CF (NCT07692594)
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Radiographic Evaluation, Bone Density
Effect of Thymoquinone 0.2% Gel on Bone Density, Bone Width, and Socket Preservation After Tooth Extraction
This study aims to evaluate the clinical and radiographic effects of 0.2% Thymoquinone gel on bone density, bone width, and socket preservation after tooth extraction.
- Conditions
- Radiographic Evaluation, Bone Density, Bone Width, Socket Preservation
- Trial name
- NCT07765745
- Testing
- Gel foam, Thymoquinone gel + gel foam, Nano-formulated 0.2% thymoquinone gel + gel foam
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Kafrelsheikh University