Clinical trials: Evidence-based Practices
Mental Health
Novel Methods for Implementing Measurement-Based Care for Youth in Low-resource Environments
This study will visit 4 community mental health clinics in Washington state and work with clinic staff to find out if staff are regularly evaluating clinical outcomes using questionnaires (which is also called measurement-based…
- Trial name
- NIMBLE (NCT05644756)
- Testing
- IMPACT Methods to Identify and Prioritize Determinants (Challenge I), Challenge and Match strategies to Prioritized Determinants (Challenge II)
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Low-immersion (Mobile Device), High-immersion (Head Mounted Display)
Developing a Virtual Reality Training Tool for Exposure Therapy: Simulated Exposure Trainer (SET)
The goal of this study is to develop a targeted virtual training program (Simulated Exposure Trainer; SET) for exposure therapy.
- Trial name
- SET-VR (NCT06706245)
- Testing
- SET-VR (computer), SET-VR (headset)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Bradley Hospital
Opioid Use Disorder (OUD)
HEALing Communities Study
This study will test the impact of implementing the Communities That Helping to End Addiction Long-term (HEAL) intervention on opioid overdose deaths within 67 highly affected communities with the goal of reducing opioid overdose…
- Trial name
- NCT04111939
- Testing
- Communities That HEAL, Wait-list control
- Where
- 4 sites in United States
- Volunteers
- 67 people
- Sponsor
- RTI International
Hypertension
VISN Collaborative for Improving Hypertension Management With ATHENA-HTN
This project is a VA HSR\&D-funded Quality Enhancement Research Initiative (QUERI) project to translate into practice evidence about clinical management of primary hypertension.
- Trial name
- HTN (NCT00374452)
- Testing
- ATHENA-CDS-HTN plus Guideline Link, Guideline Link Only
- Where
- 7 sites in United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Cocaine Use Disorder
Neurocognitive Factors in Substance Use Treatment Response: The Ways of Rewarding Abstinence Project
The proposed work will investigate changes in brain signaling and cognitive functioning that support recovery from addiction, as well as use of pretreatment neurocognitive functioning to inform substance use treatment planning.
- Trial name
- WRAP (NCT03799341)
- Testing
- Prize-Based Contingency Management, Treatment As Usual Outpatient Substance Use Treatment
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- VA Office of Research and Development
Decision Making
Practice Guidelines Grading Systems
Clinical practice guidelines (CPG) are systematically developed statements to assist practitioner and patient decisions about appropriate health care for specific clinical circumstances.
- Trial name
- NCT00940290
- Testing
- Graded Clinical Recommendation
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey
Neoplasms
Evaluating the Impact of Patient-Centered Oncology Care
The National Committee for Quality Assurance has worked with the National Coalition for Cancer Survivorship, the American Society of Clinical Oncology, Oncology Management Services, Independence Blue Cross, and RAND, as well as a…
- Trial name
- NCT02110758
- Testing
- Pilot of Patient-Centered Oncology Care
- Where
- United States
- Volunteers
- 125,250 people
- Sponsor
- National Committee for Quality Assurance
Implementation, Behavioral Symptoms
Working to Implement and Sustain Digital Outcome Measures
This study will investigate the effects of an organizational implementation strategy called Leadership and Organizational Change for Implementation (LOCI), relative to training and technical assistance only, on fidelity to, and…
- Trial name
- WISDOM (NCT04096274)
- Testing
- Leadership for Organization Change and Implementation (LOCI), Training and Technical Assistance Only
- Where
- 4 sites in United States
- Volunteers
- 686 people, healthy volunteers welcome
- Sponsor
- Boise State University
Child Maltreatment, Implementation
A Technology-Enhanced Approach for Implementing Evidence-Based Practices in Child Welfare
In this study, a computer-assisted adaptation of SafeCare, an evidence-based home visiting program, will be developed and tested in child welfare.
- Conditions
- Child Maltreatment, Implementation, Technology
- Trial name
- NCT02430337
- Testing
- Technology-Assisted SafeCare, SafeCare
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Health Behavior
Training LHDs to Disseminate Evidence-Based Interventions to Small Worksites
The proposed project will advance implementation science by comparing the effectiveness of different levels of technical support in an important but understudied community-based setting: local health departments.
- Trial name
- NCT03930420
- Testing
- Connect to Wellness
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Washington
Diabetes
Using Practice Facilitation and Operationalizing Referral Information Technology to Increase DSMES Utilization
This is a pilot and feasibility study of a pragmatic cluster randomized trial that utilizes health information technology and practice facilitation to address referral barriers and increase clinician awareness and motivation to…
- Trial name
- NCT05472142
- Testing
- UP FOR IT - practice facilitation, UP FOR IT - health information technology
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Mary Lacy
Frontotemporal Dementia, Dementia
Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)
The protocol is organized into three Phases - In Phase I an online training program will be developed in "Care of Persons with Dementia in their Environments" (COPE) -an evidence-based bio-behavioral dementia program -using…
- Conditions
- Frontotemporal Dementia, Dementia, Multi-Infarct Dementia, Vascular Dementia
- Trial name
- NCT04165213
- Testing
- Care of Older Persons in their Environment (COPE) online module training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Rare Diseases
FACE for Children With Rare Diseases
Children with ultra-rare or complex rare diseases are routinely excluded from research studies because of their conditions, creating a health disparity.
- Trial name
- FACE-Rare (NCT04855734)
- Testing
- FAmily CEntered (FACE) pACP Intervention
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's National Research Institute
Heart Failure, Heart Failure Hospitalization
Teach-Back Discharge Education to Improve Self-Care and Reduce 30-Day Readmissions in Heart Failure Patients
This study aimed to improve how patients with heart failure understand and manage their condition after leaving the hospital. Many heart failure patients are readmitted within 30 days due to confusion about their discharge…
- Conditions
- Heart Failure, Heart Failure Hospitalization, Readmission, Hospital
- Trial name
- NCT07280208
- Testing
- Teach-Back Discharge Education
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Nova Southeastern University
Depression
Remote Training in Evidence-based Practices for Clinicians Who Work With Migrant Workers
This study will compare training as usual to automated training using an intelligent tutoring system in training bachelors (BA) level social workers in cognitive behavioral therapy (CBT).
- Trial name
- NCT03515226
- Testing
- ITS based training, Traditional Training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Washington
Hypertension, Pulmonary
Piloting Mindfulness Meditation Program for Underserved Racial Minority Adults With Pulmonary Hypertension
The MMPH program will include two Zoom-delivered sessions (Weeks #1 \& #4), six video-recorded sessions (Weeks #2, #3, #5, #6, #7, #8), and daily mindfulness meditation practice using a mobile APP during an eight-week study…
- Trial name
- MMPH (NCT05387889)
- Testing
- Mindfulness Meditation for Pulmonary Hypertension (MMPH)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- State University of New York at Buffalo
Implementation Science
An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention
Study objectives are to design and pilot test a novel, exposure-based implementation strategy (EBIS) directly targeting clinician anxiety and low self-efficacy for use of evidence-based suicide screening, assessment, and…
- Trial name
- NCT05172609
- Testing
- Exposure Based Implementation Strategy (EBIS), Implementation as Usual (IAU)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Dental Pulp Exposure
Pulp Capping With Two Different Agents
The purpose of this study is to determine if MTA or calcium hydroxide are more effective as pulp capping agents
- Trial name
- MTA (NCT00812877)
- Testing
- Mineral Trioxide Aggregate, Calcium Hydroxide
- Where
- United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Alcohol Consumption
Implementing Evidence-Based Mental Health Practices in Primary Care
This research study will examine the effectiveness of a brief, computerized motivational intervention plus treatment-as-usual to treatment-as-usual alone for treating alcohol misuse in Veterans presenting to primary care.
- Trial name
- NCT00996775
- Testing
- brief alcohol intervention, standard care
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Pit-and-Fissure Sealants
An Implementation Strategy for the Adoption of an Evidence-Based Guideline for Pit-and-Fissure Sealants
The purpose of this implementation science study is to determine whether Deliberative Loops are effective in increasing providers' adherence to the non-cavitated caries component of the American Dental Association's…
- Trial name
- DISGO (NCT04682730)
- Testing
- Deliberative Loop
- Where
- United States
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh