Clinical trials: Evisceration
Pelvic Exenteration, Advanced Pelvic Malignancy
A Contemporary Review of Surgical Approaches in Pelvic Exenterative Surgery
Minimally-invasive surgery (MIS) techniques have revolutionised the approach to rectal cancer surgery. With increasing experience, surgeons have began to utilise these platforms increasingly in the context of pelvic exenteration…
- Conditions
- Pelvic Exenteration, Advanced Pelvic Malignancy, Locally Advanced Rectal Cancer
- Trial name
- NCT04948762
- Where
- Ireland
- Volunteers
- 1,000 people
- Sponsor
- St Vincent's University Hospital, Ireland
Locally Advanced Pelvic Cancer That Require Pelvic Exenteration
Laparoscopic Robot-assisted Pelvic Exenteration for Pelvic Primary and Recurrent Cancers
The Radium Hospital Oslo University Hospital Estimated date of first patient enrolled: 3rd quarter 2021 Anticipated recruitment period: 4 years Estimated date of last patient completed: 4th quarter 2025 Locally advanced pelvic…
- Trial name
- NCT05186493
- Testing
- robot-assisted total pelvic exenteration
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Oslo University Hospital
Abdominal Wall Defect, Abdominal Wall Hernia
The Efficacy and Security of the Small Stitch Technique in Emergency Surgery
This study evaluates the abdominal closure technique in emergency surgery. Half of participants will be perform the classic Large Stitch technique, while the other half will undergo the Small Stitch technique.
- Conditions
- Abdominal Wall Defect, Abdominal Wall Hernia, Eventration, Evisceration; Operation Wound
- Trial name
- STCU (NCT03765060)
- Testing
- Monomax® 2/0 HR26, Monomax® 1 HR48
- Where
- Spain
- Volunteers
- 105 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Evisceration; Traumatic, Eye
Comparing Double VS Quadruple Flap for Securing Ball Implants After Eye Ball Evisceration
The primary objective of this interventional study is to compare the efficacy and outcomes of the double flap and quadruple flap closure techniques in securing ball implants after evisceration. Specific objectives include: 1.
- Trial name
- NCT06636630
- Testing
- Quadruple scleral flap, Double scleral flap
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Fayoum University Hospital
Pain, Postoperative
Exparel Injection for Postoperative Orbital Pain
After surgery to remove the eye, either by enucleation or evisceration, patients have variable levels of pain for several postoperative days.
- Trial name
- NCT02381353
- Testing
- Bupivacaine
- Where
- 2 sites in United States
- Volunteers
- 88 people
- Sponsor
- Mayo Clinic
Gynecologic Cancer
Performance of Whole Body MRI in Extraplevic Disease Detection in Patients Undergoing Pelvic Exenteration for Gynecological Maligniancies
The aim of this prospective observational diagnostic study is to investigate the diagnostic accuracy od extrapelvic disease detection using Whole-body-MRI (WB-MRI) in patients with gynecologic cancer candidate to the pelvic…
- Trial name
- WHOLE BODY (NCT05816005)
- Where
- Italy
- Volunteers
- 71 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma
Pelvic Exenteration in Treating Patients With Recurrent Cervical Cancer
This phase II trial is studying how well pelvic exenteration works in treating patients with recurrent cervical cancer. Pelvic exenteration may be effective in treating recurrent cervical cancer.
- Conditions
- Cervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Small Cell Carcinoma, Cervical Squamous Cell Carcinoma
- Trial name
- NCT00217633
- Testing
- Conventional Surgery
- Where
- 39 sites in United States, Spain
- Volunteers
- 38 people
- Sponsor
- Gynecologic Oncology Group
Rectal Cancer Recurrent, Pelvic Exenteration
Postoperative Results and Outcomes in Surgical Pelvic Exenteration
The purpose of this study is to evaluate the feasibility of a standardized surgical and care process for patients with locally advanced or recurrent rectal cancer that has spread to nearby pelvic organs.
- Conditions
- Rectal Cancer Recurrent, Pelvic Exenteration, Advanced Rectal Cancer
- Trial name
- PROS-PE (NCT07395505)
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Cervical Carcinoma, Endometrial Carcinoma
Longitudinal Evaluation of Women Undergoing Pelvic Surgery for the Treatment of Gynecologic Cancer
The study investigates whether certain characteristics of gynecological cancer can help researchers predict how well a patient recovers from surgery to remove the lower colon, rectum, and bladder, and create openings through…
- Conditions
- Cervical Carcinoma, Endometrial Carcinoma, Malignant Female Reproductive System Neoplasm, Vaginal Carcinoma
- Trial name
- NCT00791635
- Testing
- Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- M.D. Anderson Cancer Center
Bladder Cancer, Cystectomy
Supporting Sexual Recovery in Women With Bladder Cancer
This study looks at how bladder cancer and removing the bladder can affect women's sexual well-being. Bladder cancer can be more serious in women, and treatment like bladder removal can impact how they feel about themselves and…
- Conditions
- Bladder Cancer, Cystectomy, Female Sexual Dysfunction
- Trial name
- SPARC (NCT07091565)
- Testing
- Qualitative interview/Focus group
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King's College London
Vascular Reconstruction in Pelvic Exenterative Surgery
The Role of Vascular Reconstruction in the Setting of Pelvic Exenteration
Local invasion or abutment of a major vascular structure was once a major deterrent to planned oncological resection. Improvements in radiological assessment and vascular surgical techniques have enabled resection of major blood…
- Trial name
- NCT04948879
- Testing
- Vascular resection/reconstruction
- Volunteers
- 100 people
- Sponsor
- St Vincent's University Hospital, Ireland
Cancer
Impact of Forearm Free Flap in Orbital Exenteration Reconstruction
Orbital exenteration is the en bloc removal of the entire orbital contents. This mutilating surgical technique is reserved for the management of certain malignant orbito-palpebral tumors or those that secondarily invade the…
- Trial name
- REXOR (NCT05255315)
- Testing
- Comparative analysis comparing the morbidity of the antebrachial free flap to that of the temporal flap flap during exenteration as well as the rate of fitting patients with epithesis.
- Where
- France
- Volunteers
- 72 people
- Sponsor
- Institut Curie
Cancer
Exenteration: Quality of Life Study and Rehabilitation Rate According to the Reconstruction Technique (ETRE)
Prospective monocentric quality of life study. Including all patients who have been exentered at the Institut Curie Paris, from January 2004 to December 2019, proposing to compare the reported quality of life of patients…
- Trial name
- ETRE (NCT04994730)
- Testing
- Quality of life according to the reconstruction technique
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Institut Curie
Total Exenteration, Anterior or Posterior Pelvic Exenteration
Quality of Life in Patients Undergoing Total Pelvic Exenteration
The purpose of this study is to learn more about the personal experiences of patients who are treated with pelvic exenteration surgery.
- Conditions
- Total Exenteration, Anterior or Posterior Pelvic Exenteration, Gynecologic Malignancies, Colorectal Malignancies
- Trial name
- NCT00597805
- Testing
- questionnaires/interviews
- Where
- 8 sites in United States
- Volunteers
- 94 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Colo-rectal Cancer
Psychological distREsS hipEc oR pelVic Exenteration
The purpose of this study is to describe type and extent of psychological distress (adverse effects) in patients undergoing surgery for colorectal cancer with peritoneal metastases and after surgery for colorectal cancer with…
- Trial name
- PRESERVE (NCT04956107)
- Where
- 3 sites in Denmark, Sweden
- Volunteers
- 225 people
- Sponsor
- University of Aarhus