Clinical trials: Executive Function
TBI Traumatic Brain Injury
Noninvasive Brain Stimulation to Enhance Cognition at Home Following a TBI.
The purpose of this study is to examine the feasibility and preliminary efficacy of using transcutaneous vagus nerve stimulation (tVNS) at home, to enhance cognitive recovery in patients with mild-moderate traumatic brain injury…
- Trial name
- NCT07428980
- Testing
- Transcutaneous Vagus Nerve Stimulation (tVNS)
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Shirley Ryan AbilityLab
Young Healthy Adults
Effect of High-Intensity Interval Training Exercise on Cognitive Function of Young Adults
To explore the sustainability of the acute effect of High Intensity Interval Training (HIIT) on executive function in young adults.
- Trial name
- NCT06621550
- Testing
- High Intensity Interval Training
- Where
- Hong Kong
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Premature Birth
Brain Training in Preterm Children at Risk for Inattention, Hyperactivity, and Executive Function Impairment
The purpose of this study is to determine if different forms of child-friendly, computer-based puzzles and games ("brain training") targeting executive function (EF) skills (i.e., thinking, problem-solving) result in improvements…
- Trial name
- NCT02588391
- Testing
- Brain Training (Active), Brain Training (Passive), Brain Training (Active or Passive)
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Stanford University
Sleep, Sleep Hygiene
The Goodnight Screen Media Study
To test the timing of evening tablet use on children's circadian phase and sleep (i.e., sleep onset and sleep duration) compared to no screen media use.
- Trial name
- NCT05820555
- Testing
- Timed evening technology and digital media use (tablet use), no technology and digital media use (screen media use)
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Cognitive Impairment, Executive Dysfunction
Vascular Mechanisms for the Effects of Loss of Ovarian Hormone Function on Cognition in Women
Complaints about memory and thinking are common in women as they go through menopause and estrogen levels fall. The ovarian hormone estrogen is important for supporting normal cognitive function, and changes in brain activity and…
- Conditions
- Cognitive Impairment, Executive Dysfunction, Endothelial Dysfunction, Cardiovascular Disease
- Trial name
- NCT02122198
- Testing
- Leuprolide acetate, Estradiol, Medroxyprogesterone
- Where
- 2 sites in United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Healthy, Healthy Adult Participants
Muévete conCiencia: Exercise and Mind-Body Program for University Students
The goal of this clinical trial is to evaluate whether different physical exercise and mind-body interventions can improve executive functions and reduce stress in first-year university students.
- Trial name
- NCT07443904
- Testing
- Motor-Cognitive Dual-Task Exercise (DT), Tai Chi Mind-Body Exercise (TC), Cognitive Stimulation (CS)
- Where
- Chile
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Universidad San Sebastián
Stroke
Effects of Combined Cognitive Training and Rhythmic Auditory Stimulation in Treadmill Training After Stroke
The objective of this study is to compare the effects of progressive combined cognitive training and rhythmic auditory stimulation to treadmill training (combined group), cognitive treadmill training (cognitive group), rhythmic…
- Trial name
- NCT06000644
- Testing
- Combined group, Cognitive group, Rhythmic group
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung University
Cognitive Change, Diet, Healthy
Optimized Tailored Interventions in Metabolic and Lifestyle Outcomes (OPTIMAL)
The goal of this clinical trial is to learn if increasing adherence to a Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet pattern improves brain and heart health relative to a healthy control diet in…
- Conditions
- Cognitive Change, Diet, Healthy, Metabolic Syndrome, Protection Against
- Trial name
- NCT06605898
- Testing
- MIND Diet, Control Diet
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Mild Cognitive Impairment, Memory Impairment
Enhancing Frontal Lobes Plasticity in Mild Cognitive Impairment
More than 5 million people live with Alzheimer's dementia (AD) in North America. No effective treatment exists yet probably because by the time AD has developed it is too late to intervene.
- Trial name
- PAS-MCI (NCT04583215)
- Testing
- Paired Associative Stimulation (PAS)
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Depression in Adolescence, Adverse Childhood Experiences
Shaping Actions and Responses to Emotions
The primary objective of this research is to examine two brief interventions for depression, Behavioral Activation (BA), and Problem Solving Therapy (PST), to investigate whether exposure to adverse childhood experiences…
- Trial name
- ShARE (NCT04719949)
- Testing
- Behavioral Activation (BA) Therapy, Problem Solving Therapy (PST)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Pittsburgh
VITAMIN D DEFICIENCY
An Evaluation of the Effect of Vitamin D Supplementation on the Cognitive Function of Older Subjects With Low Levels of This Vitamin
Background: Ageing is associated with an increased risk of cognitive decline and depression. Vitamin D plays an important role in many of the symptoms and conditions related to advanced age, including impaired balance, falls and…
- Trial name
- NCT02381600
- Testing
- Vitamin D
- Where
- Israel
- Volunteers
- 1 people
- Sponsor
- Meir Medical Center
Autism Spectrum Disorder
Augmented Reality for Behavior and Executive Function of Children With Autism Spectrum Disorder
The aim of the study is to determine the effects of usage of augmented reality for Restricted and repetitive behavior and executive function of children with autism spectrum disorder
- Trial name
- NCT05962047
- Testing
- Games of WonderTree Augmented Reality, Traditional therapy
- Where
- Pakistan
- Volunteers
- 18 people
- Sponsor
- Riphah International University
Healthy Aging
Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game
Executive control processes involve initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior.
- Trial name
- NCT05506852
- Testing
- Web-based training strategy, Web-based regular training (no strategy)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Columbia University
Health Services for the Aged
Multicomponent Exercise on Executive Function and Balance
The present study is to examine the effects of a multicomponent exercise on executive function and balance in pre-frail older adults.
- Trial name
- NCT03611192
- Testing
- Multicomponent exercise, Home-program exercise
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Behavioral Problem of Child
Japi: Cognitive, Emotional and Social Stimulation for Preschool Children
Mental health disorders are one of the leading causes of illness globally, and their relevance is expected to increase. Low and Middle Income Countries (LMIC), already facing psychological and behavioral issues due to chronic…
- Trial name
- Japi (NCT06420544)
- Testing
- JAPI: Cognitive, Emotional and Social Stimulation for Preschool Children
- Where
- 2 sites in Chile
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Disruptive Behavior Disorder, Childhood Onset, Disruptive Behavior
Executive Function and Parenting in Childhood
Deficits in executive functioning (EF) disproportionately impact children living in poverty and increase risk for psychopathology, particularly disruptive behavior disorders.
- Conditions
- Disruptive Behavior Disorder, Childhood Onset, Disruptive Behavior, Executive Function
- Trial name
- EPIC (NCT06241300)
- Testing
- Chicago Parent Program
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Illinois Chicago
Depression in Old Age, Depression
Enhancing Processing Speed and Executive Functioning in Depressed Older Adults With Computerized Cognitive Training
The purpose of this research study is to determine how treatment response may change depending on how studies are designed, and if mobile cognitive training can be used to improve treatment response in depressed older adults.
- Trial name
- NCT04836533
- Testing
- Experimental: Computerized Cognitive Training, Experimental: Open-label antidepressant treatment, Active Comparator: Solitaire Training
- Where
- United States
- Sponsor
- Queens College, The City University of New York
Autism, Autism Spectrum Disorder
Cognitive Training in Virtual Reality for Autism
The Virtual Reality Rehabilitation System (VRRS) is an innovative tool for motor and cognitive rehabilitation that has shown promising results in developmental populations, with evidence of feasibility, safety, acceptability, and…
- Trial name
- NCT07643649
- Testing
- Experimental Group, Control Group
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Exercise
Effects OF Acute Aerobic Exercise On Higher Cerebral Functions
We are comparing higher cerebral functions including cognitive flexibility, inhibitory control and working memory in healthy young adults between a group of acute aerobic exercise and a control group.
- Trial name
- NCT05861726
- Testing
- Aerobic exercise, None (control group)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Khyber Medical College, Peshawar
Congenital Heart Disease
Executive Functions in Adults With Congenital Heart Disease
Research in children with congenital heart disease (CHD) requiring cardiopulmonary bypass surgery in the neonatal period or during early childhood has shown that the survival rate for this population has dramatically increased…
- Trial name
- NCT04041557
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich