Clinical trials: Executive Function (Cognition), open to volunteers
Healthy Volunteers
Classroom Break, Cognition, and Fitness in Elementary School Children
The goal of this randomized controlled trial is to learn about the effect of a 12-week school-based intervention combining mindfulness with high-intensity interval training (MF-HIIT), MF-only intervention, and HIIT-only…
- Trial name
- NCT06258941
- Testing
- MF-HIIT, HIIT-only, MF-only
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Purdue University
Cognitive Function Abnormal, Atrial Fibrillation (AF)
Low-frequency Electrical Stimulation for Cognitive Enhancement in Atrial Fibrillation
Cognitive function in patients with atrial fibrillation (AF) is often impaired due to the complex influence of various factors (cerebral hypoperfusion, neurodegeneration, microemboli, hypertension, chronic inflammation).
- Trial name
- LESCAF (NCT07063381)
- Testing
- tVNS
- Where
- 2 sites in Russia
- Volunteers
- 60 people
- Sponsor
- Bakulev Scientific Center of Cardiovascular Surgery
Myeloid Malignancies
Exercise Intervention to Support Recovery After Allogeneic Stem Cell Transplantation in Adults With Myeloid Blood Disorders
The goal of this clinical trial is to learn how a 12-week exercise intervention affects recovery after allogeneic stem cell transplantation in adults with a myeloid blood disorder.
- Trial name
- RESTART (NCT07868653)
- Testing
- Multimodal Exercise Intervention
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- Universität Duisburg-Essen
Neurofibromatosis 1 (NF1), Executive Function (Cognition)
Cognitive Intervention for Children and Adolescents With NF1
Psychological interventions have been shown to be effective for managing cognitive and mental health challenges in different patient populations.
- Conditions
- Neurofibromatosis 1 (NF1), Executive Function (Cognition), Cognitive Intervention
- Trial name
- NCT07869914
- Testing
- Unstuck and On Target!
- Volunteers
- 60 people
- Sponsor
- The Hospital for Sick Children
Parkinson's Disease, Mild Cognitive Impairment
rTMS to Improve Cognition in Parkinson's
The purpose of this study is to examine safety, feasibility, and the behavioral and brain effects of a non-invasive treatment, repetitive transcranial magnetic stimulation (rTMS), for Veterans with Parkinson's disease or atypical…
- Trial name
- TMSCogReP (NCT03836950)
- Testing
- MagVenture MagProX100 stimulator (MagVenture, Falun, Denmark)
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- VA Office of Research and Development
Stroke
Efficacy of Music-Based Telerehabilitation After Stroke
The goal of this clinical trial is to learn if a music-based telerehabilitation intervention implemented at home works to treat different kinds of neurological deficits caused by stroke.
- Trial name
- NCT06804304
- Testing
- Music-based telerehabilitation
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- Teppo Sarkamo
Pediatric Obstructive Sleep Apnea, Cognition
Observational Study on the Impact of Obstructive Sleep Apnea on Executive Function and Empathy Development in Children
This study aims to investigate the effects of obstructive sleep apnea (OSA) on executive function and empathy development in children aged 3-12 years.
- Conditions
- Pediatric Obstructive Sleep Apnea, Cognition, Empathy, EEG
- Trial name
- OSA-EFED (NCT06850220)
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Soochow University
Mild Cognitive Impairment, Walking
Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment
The goal of this randomised clinical trial is to investigate the effectiveness of an innovative therapeutic exercise program emphasizing in dual-task exercises in people with amnestic Mild Cognitive Impairment.
- Conditions
- Mild Cognitive Impairment, Walking, Balance, Cognition
- Trial name
- MExeProMCI (NCT07334392)
- Testing
- Innovative therapeutic exercise program, Therapeutic exercise program, Flyer
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- University of Patras
Drepanocytosis, Chronic Neurological Deficiency
Transfusion Exchanges and Cognition in Sickle Cell Disease
DREPA-COG is an observational study evaluating the effect of exchange transfusions on cognitive function in adults with severe sickle cell disease (SS or Sβ0).
- Trial name
- DREPA-COG (NCT07168447)
- Where
- 6 sites in France
- Volunteers
- 85 people
- Sponsor
- Centre Hospitalier St Anne
Stroke, Ischemic
Cognitive Strategies for Optimizing Brain Health And Managing Transgenerational Vascular Risk Factors Post-Stroke
People living with the cognitive effects of stroke are at risk for recurrent stroke and further cognitive decline. Also problematic is that stroke risk clusters in families and biological family members of people who have…
- Trial name
- CHAMPS-TR (NCT06479174)
- Testing
- CHAMPS-TR
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Body Image, Cognition
3-Dimensional Evaluation of Body Perception
The goal of this observational study is to evaluate the changing body perception of amputees aged 18-65 years using prostheses through different personal perspectives of the right-left distinction.
- Conditions
- Body Image, Cognition, Decision Making, Visuospatial/Perceptual Abilities
- Trial name
- NCT06985329
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Trakya University
Menopause, Healthy Adult
Cyclic vs. Constant Estradiol: Regimens' Effects on Brain Health
The purpose of this study is to learn more about how estradiol patch treatment affects brain processes, health, and wellbeing.
- Conditions
- Menopause, Healthy Adult, Brain, Postmenopausal
- Trial name
- CEREBRA (NCT07831499)
- Testing
- Cyclic Estradiol, Continuous Estradiol
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Preterm
Preschool Outcomes of a Previous RCT - ReDiMOM (NCT04540575)
This study will evaluate neurodevelopmental, health, and economic outcomes in preschool children born very preterm that participated in a randomized trial of an economic intervention designed to increase breastmilk feedings while…
- Trial name
- NCT07702357
- Testing
- This is a an observational prospective cohort study of a previous interventional trial (NCT04540575)
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- Rush University Medical Center
Parkinson Disease
Cognitive-motor Training in Parkinson Disease
Literature reviews showed the cognitive-motor training that combines cognitive tasks may enhance cognitive functions more effectively than individual interventions.
- Trial name
- NCT06588439
- Testing
- Cognitive-motor training, Conventional physiotherapy
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Yang Ming Chiao Tung University
Post-partum, Women
Creatine for Recovery and Thinking in Mothers
The purpose of this randomized, double-blind, parallel-group trial is to compare the effects of two doses of creatine monohydrate (5 g/day versus 10 g/day) administered for four weeks in postpartum women.
- Trial name
- CREATE-MOM (NCT07795853)
- Testing
- Creatine Monohdyrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of North Carolina, Chapel Hill
Mild-to-moderate Depression, Neural Activity
Probiotics for Depressive Symptomatology and Neural Activity.
This study aims to investigate the acute and chronic effects of 16-week probiotic supplementation (Ecologic® Barrier) on depressive symptoms and neural activity in those with mild-to-moderate depression.
- Conditions
- Mild-to-moderate Depression, Neural Activity, Executive Function (Cognition)
- Trial name
- PRODAN (NCT07667530)
- Testing
- Ecologic® Barrier
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- University of Reading
Delirium, Impaired Cognition
Simultaneous Recumbent Cycling and Cognitive Training
Intensive care units (ICU) provide life-saving care for nearly five million people annually. Up to 80% of patients receiving care in an ICU experience at least one episode of delirium.
- Trial name
- NCT04556227
- Testing
- Simultaneous Cycle/Cognitive Training
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Missouri, Kansas City
Insomnia
Online COgnitive Behavioural Therapy for Sleep and Mental Health for Older Adults With Insomnia and Subjective Cognitive Complaints
The goal of this randomized controlled clinical trial is to assess a novel cognitive-behavioral program for sleep and mental health using a multidomain web platform (eCBTi+) in participants with insomnia and subjective cognitive…
- Trial name
- e-COSMOS (NCT06032377)
- Testing
- cognitive behavioral therapy for sleep, anxiety, and depression, education about healthy nutrition habits and communication in older age
- Where
- 2 sites in Canada
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Motor-Cognitive Function, Dual-Task Walking
Effects of Adapted Argentine Tango Training Frequency on Dual-Task Walking
This randomized controlled trial will examine whether the frequency of adapted Argentine tango training affects walking and cognitive function in adults aged 55 to 60 years when the total weekly intervention time is kept the…
- Conditions
- Motor-Cognitive Function, Dual-Task Walking, Balance
- Trial name
- AAT-FREQ (NCT07800494)
- Testing
- Distributed Adapted Argentine Tango Training, Concentrated Adapted Argentine Tango Training, Health Education and Low-Intensity Stretching
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Xi'an Medical University
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife