Clinical trials: Exercise Induced Bronchoconstriction
Asthma
Effect of Different Anti-Asthmatic Treatments on Lung Function and on Exercise-Induced Bronchoconstriction in Children With Asthma
The present study was conducted to determine the effects of four week treatment with budesonide, montelukast, budesonide with montelukast and budesonide with formoterol in children with atopic asthma on lung function: forced…
- Trial name
- NCT00490243
- Testing
- budesonide and montelukast, budesonide and formoterol, montelukast
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Lodz
Asthma, Exercise-Induced, Asthma
Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma
The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments.
- Trial name
- NCT04302610
- Testing
- Heat and Moisture Exchange mask (ColdAvenger® expedition balaclava, USA,
- Volunteers
- 26 people
- Sponsor
- University of Kent
Asthma in Children, Obesity, Childhood
Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity
Guidelines from the American Thoracic Society strongly recommend interval warm-up exercise before planned exercise to reduce exercise-induced bronchoconstriction severity.
- Conditions
- Asthma in Children, Obesity, Childhood, Exercise Induced Bronchospasm
- Trial name
- NCT03586544
- Testing
- Albuterol Sulfate, Interval Warm-up exercise
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Asthma
Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Combining fish oil and vitamin C supplementation will provide a greater anti-inflammatory effect against developing exercise-induced bronchoconstriction (EIB) than either nutritional supplement alone.
- Trial name
- NCT01057615
- Testing
- Fish Oil, Ascorbic Acid
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
Bronchospasm, Exercise-Induced
Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
This will be a double-blind placebo-controlled study in which we plan to study 40 competitive endurance athletes. We will conduct an exercise test to evaluate maximal oxygen uptake and 2 exercise challenge tests to provoke EIA.
- Trial name
- STAMINA (NCT01691079)
- Testing
- ipratropium bromide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Asthma, Bronchoconstriction
Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol
The purpose of this study is to investigate, using an exercise challenge approach, the dose response of levalbuterol HFA MDI in adolescent and adult subjects with asthma
- Trial name
- NCT00685425
- Testing
- Levalbuterol HFA MDI, Racemic Albuterol
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Sumitomo Pharma America, Inc.
Exercise Induced Bronchospasm
Hyperventilation Versus Exercise Testing Sensitivity in Exercise Induced Asthma
The diagnosis of exercise-induced bronchospasm (EIB) is difficult. The metacholine challenge test is not enough specific for the diagnosis of EIB.
- Trial name
- HYVES (NCT03063424)
- Testing
- Eucapnic voluntary hyperventilation, Exercise challenge on a cycle ergometer
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Exercise Induced Asthma
Mediator Release During Exercise-induced Bronchoconstriction
This study will compare the inflammatory response in induced vs inhibited exercise induced bronchoconstriction (EIB) in patients with a medical diagnosis of asthma/EIB.
- Trial name
- NCT03524053
- Testing
- Exercise induced bronchoconstriction, Inhibited EIB
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Brunel University
Childhood Asthma
More Relaxation by Deep Breath on Methacholine
Deep inhalation (DI) dilates normal airway precontracted with methacholine. The fact that this effect is diminished or absent in asthma could be explained by the presence of bronchial inflammation.
- Trial name
- SouProvocBro (NCT03696602)
- Testing
- bronchial provocation test
- Volunteers
- 78 people
- Sponsor
- Central Hospital, Nancy, France
Asthma in Children
Effect of Mouth Breathing on Exercise Induced Bronchoconstriction.
Introduction: Exercise induced bronchoconstriction (EIB) is a common finding in the pediatric population with and without asthma.
- Trial name
- NCT05376436
- Testing
- Exercise challenge test (ECT)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Asthma, Child
NIV Application in the Treatment of Asthmatic Children
Asthma is characterized by recurrent episodes of bronchospasm, bronchial hyperresponsiveness and chronic airway inflammation and pharmacological treatment for this condition is done with bronchodilators and anti-inflammatory.
- Conditions
- Asthma, Child, Bronchial Spasm
- Trial name
- NCT02939625
- Testing
- muscle training, Continue Positive Airway Pressure, bilevel positive airway pressure
- Where
- Brazil
- Volunteers
- 68 people
- Sponsor
- University of Nove de Julho
Asthma
A Placebo and Active Controlled Study of ONO-6950 in Asthmatic Patients
The primary objectives of this study are: i. to determine the effect of single oral doses (20 and 200 mg) of ONO-6950 versus placebo on exercise induced bronchoconstriction (EIB) as percent attenuation in the decrease of forced…
- Trial name
- NCT01536041
- Testing
- ONO-6950, Montelukast
- Where
- 9 sites in United States
- Volunteers
- 59 people
- Sponsor
- Ono Pharma USA Inc
Exercise Induced Asthma
Two Investigational Drugs in the Prevention of Airway Constriction Brought on by Exercise in Participants With Asthma (0476-911)
The purpose of this study is to determine the effect of four weeks of treatment with two investigational drugs (oral versus inhaled administration) plus an inhaled medication in the treatment of airway constriction brought on by…
- Trial name
- NCT00127166
- Testing
- Montelukast sodium, Salmeterol xinafoate, Fluticasone propionate
- Volunteers
- 154 people
- Sponsor
- Organon and Co
Asthma
How Different Beta-2 Receptor Genotypes Affect an Asthmatic's Response to Regular Salmeterol Treatment
The purpose of the study is to find out how well a long-acting beta agonist like salmeterol works in people with different forms of the same gene.
- Trial name
- SECS (NCT00595361)
- Testing
- salmeterol
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Brigham and Women's Hospital
Asthma, Asthma, Exercise-Induced
Adaptation to Ozone in Individuals With Asthma/Exercise-induced Bronchoconstriction
Researchers found that impairments in the cardiopulmonary system caused by acute exposure to ozone were outweighed by repeated exposures to ozone.
- Conditions
- Asthma, Asthma, Exercise-Induced, Exercise Induced Asthma, Exercise Induced Bronchospasm
- Trial name
- NCT05105529
- Testing
- Exercise, Ozone, Filtere Air
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Sleep Apnea, Obstructive, Asthma, Exercise-Induced
Pulmonary Disorders During Exercise in Patients With Obstructive Sleep Apnea
Purposes: 1. To investigate whether patients with severe obstructive sleep apnea syndrome (OSAS) are at higher risk for exercised-induced bronchoconstriction (EIB) due to baseline airway inflammation compared with age, gender…
- Trial name
- NCT00916773
- Testing
- continuous positive airway pressure (CPAP)
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Exercise-induced Bronchospasm
Vitamin C & Exercise Induced Bronchoconstriction (EIB)
The purpose of this research is to assess the association between diet and pulmonary function during standardized EIB testing. Determine the effect of Vitamin C supplementation on airway inflammatory markers and…
- Trial name
- NCT03610932
- Testing
- Vitamin C
- Where
- United States
- Sponsor
- University of Kansas Medical Center
Exercise-induced Bronchoconstriction, Air Pollution
Exercise in Air Pollution and Lung Health in Asthmatics
When exposed to air pollution, the asthma symptoms are aggravated and lung function is impaired. Due to high breathing rates and volumes, physically active individuals are at particular risk of lung health impairment due to the…
- Trial name
- NCT02252302
- Testing
- Rest (Sitting on chair), Cycling exercise, Salbutamol inhalation
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Ergogenic Athletic Performance
Anaerobic Power and Salbutamol
Athletes using inhaled β2-adrenoreceptor agonists (IBAs) win a disproportionate number of medals. However, most previous research has shown that β2 agonists do not improve exercise performance in either asthmatic or non-asthmatic…
- Trial name
- NCT02255630
- Testing
- Cycling Exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma, Bronchospasm
Single-Dose Cross-Over Study of the Effects of Albuterol-HFA in Exercise Induced Bronchoconstriction
This clinical study will evaluate and establish the protective effects of Amphastar's Albuterol Sulfate HFA Inhalation Aerosol (Albuterol-HFA), in preventing exercise-induced bronchoconstriction (EIB) in adolescent and adult…
- Trial name
- NCT00634829
- Testing
- albuterol (Armstrong Albuterol HFA), Albuterol Sulfate (Provenetil-HFA)
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Amphastar Pharmaceuticals, Inc.