Clinical trials: Exercise Induced Bronchoconstriction
Asthma
Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Docosahexaenoic acid (DHA) is a component of fish oil that is known to support a healthy cardiovascular system, maintain brain function, reduce depression, and improve inflammatory diseases.
- Trial name
- NCT01200446
- Testing
- Docosahexaenoic Acid
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Indiana University
Bronchoconstriction, Inhaled Salbutamol
Salbutamol, Pharmacogenetics and Breathing Mechanics
Athletes using asthma medications called β2-agonists win a disproportionately high number of medals at Olympic Games. Due to a large variety in the genes that affect how individuals respond to β2-agonists, the investigators will…
- Conditions
- Bronchoconstriction, Inhaled Salbutamol, Cycling Performance
- Trial name
- NCT01903785
- Testing
- Salbutamol
- Where
- Canada
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Young Athletes, Biomarker
Screening and Diagnosing Exercise-induced Bronchoconstriction in Recreational Young Athletes (12-18 y)
The purpose of this study is to validate the screening protocol to study risk factors of exercise-induced bronchoconstriction (EIB) obtained in our previous study in high-school elite athletes (NCT03587675), in recreational young…
- Conditions
- Young Athletes, Biomarker, Exercise Induced Bronchoconstriction, Adolescent
- Trial name
- NCT04103632
- Testing
- EVH test
- Where
- Belgium
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Exercise Induced Bronchoconstriction, Asthma
Exercise Induced Bronchoconstriction and Field Tests
Asthma and exercise induced bronchoconstriction (EIB) represent an important challenge for the athlete, and correct diagnosis is important as it affects health as well as performance with strict regulations concerning asthma…
- Trial name
- EXCIT (NCT04275648)
- Testing
- AsthmaTuner exercise field test
- Where
- Norway
- Volunteers
- 60 people
- Sponsor
- Karolinska Institutet
Exercise-Induced Bronchoconstriction (EIB)
Efficacy of Albuterol SPIROMAX® in Adult and Adolescent Patients With Exercise-Induced Bronchoconstriction (EIB)
The primary objective of this study is to evaluate the efficacy of a single dose (2 inhalations, 180 mcg total) of Albuterol SPIROMAX (90 mcg per inhalation) versus placebo in patients with EIB.
- Trial name
- NCT01791972
- Testing
- Albuterol Spiromax
- Where
- 6 sites in United States
- Volunteers
- 38 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Exercise Induced Bronchoconstriction
Exercise-induced Bronchoconstriction Diagnostics: Impact of a Repeated Exercise Challenge Test
The purpose of this study is to increase the knowledge of the possible diagnostic effect of exercise induced bronchoconstriction performing a repeated exercise challenge test.
- Trial name
- NCT01214551
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Norwegian University of Science and Technology
Asthma
Comparison of Combination Therapy: Montelukast and Inhaled Steroid on Exercise Induced Bronchoconstriction
The purpose of this study is to compare the effects of 2 weeks therapy of montelukast, budesonide, their combination on exercise induced bronchoconstriction (EIB) and airway inflammation in children and young adults, not on…
- Trial name
- NCT00462592
- Testing
- budesonide, montelukast
- Where
- 2 sites in Canada
- Volunteers
- 18 people
- Sponsor
- Hamilton Health Sciences Corporation
Exercise Induced Bronchospasm, Exercise Induced Asthma
Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance (IMT_EIB)
Due to the lack of studies examining the impact of inspiratory muscle training (IMT) on the severity of exercise-induced bronchoconstriction (EIB) and exercise performance, the specific aim of this study is to assess the efficacy…
- Trial name
- IMT_EIB (NCT06336681)
- Testing
- PrO2Fit Device
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Indiana University
Exercise-induced Bronchoconstriction (EIB)
The Effect of Montelukast on Difficulty in Breathing After Exercise in Pediatric Patients (MK0476-377)(COMPLETED)
This study will see if there is a change in breathing after exercising when the child receives study drug ( montelukast or placebo).
- Trial name
- NCT00534976
- Testing
- Comparator: montelukast sodium
- Volunteers
- 364 people
- Sponsor
- Organon and Co
Exercise Induced Bronchospasm, Athletes
Diagnosis of EIB in Young Elite Athletes (13-18 y)
The investigators recently observed airway inflammation and increased damage-associated molecular pattern (DAMP) level in sputum of children (age 11-12y) and adolescents (18-23y) from elite sport programs in Belgium with…
- Conditions
- Exercise Induced Bronchospasm, Athletes, Adolescent
- Trial name
- NCT03587675
- Testing
- EVH test
- Where
- Belgium
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Exercise-induced Asthma
Exercise Challenge in a Cold Chamber
The purpose of this study is to compare the exercise-challenge in a cold chamber at 2-4°C to the gold standard the metacholine challenge in subjects showing symptoms of exercise-induced bronchoconstriction.
- Trial name
- NCT02026492
- Testing
- Exercise challenge in a cold chamber, Methacholine challenge, Exercise challenge in room temperature
- Where
- Germany
- Volunteers
- 79 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Asthma
A Phase 2A Study to Evaluate the Safety and Effect on Exercise Challenge Testing of MEDI-528 in Adults With Asthma
The main objective of this study is to evaluate the safety and tolerability of multiple fixed doses of MEDI-528 in adult patients with stable asthma and exercise-induced bronchoconstriction (EIB).
- Trial name
- NCT00590720
- Testing
- MEDI528 50 mg
- Where
- 12 sites in United States, Canada
- Volunteers
- 11 people
- Sponsor
- MedImmune LLC
Exercise Induced Asthma, Exercise Induced Bronchospasm
Evaluation of Exercise Induced Bronchoconstriction Using a Novel Automated Digital Clinical Decision System
The primary objective of this study is to assess if the unstandardized field exercise challenge test (ECT) using AsthmaTuner can be performed independently by youths that have been investigated for asthma.
- Conditions
- Exercise Induced Asthma, Exercise Induced Bronchospasm, Pediatric Respiratory Diseases
- Trial name
- NCT05162703
- Testing
- AsthmaTuner
- Where
- Sweden
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Region Stockholm
Asthma
Crossover Study Comparing Fluticasone Furoate (FF)/Vilanterol (VI) Once Daily Versus Fluticasone Propionate (FP) Twice Daily in Subjects With Asthma and Exercise-Induced Bronchoconstriction (EIB)
This is a multicenter, randomized, double-blind, double-dummy, crossover study with two 2-week treatment periods separated by a 2-week wash-out period.
- Trial name
- NCT02730351
- Testing
- Fluticasone furoate/ Vilanterol 100 mcg/25 mcg, Fluticasone propionate 250 mcg
- Where
- 16 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- GlaxoSmithKline