Clinical trials: Exercise Induced Muscle Damage
Delayed Onset Muscle Soreness, Exercise-Induced Muscle Damage
Mineral-Infused Clothing for Recovery From Muscle Soreness and Muscle Damage After Exercise
The goal of this clinical trial is to learn whether wearing mineral-infused clothing helps muscles recover after a hard bout of unaccustomed exercise in healthy adults aged 18 to 45 who have not done lower-body resistance or jump…
- Trial name
- PERFICT (NCT07873866)
- Testing
- Mineral-infused garment, Non-infused control garment, Muscle-damaging eccentric exercise (drop jumps)
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- StudySetGo
Inflammation; Muscle
Effectiveness of Two Different Forms of Marine Oil on Indirect Markers of Muscle Damage and Soreness in Untrained Men
To evaluate the effects of PCSO-524®, and a blend of PCSO-24® (75%) and krill oil (25%) (ESPO-572®), on indirect markers of muscle damage, inflammation and soreness during recovery from muscle damaging exercise in untrained men.
- Trial name
- NCT03760757
- Testing
- ESPO-572®, PCSO-524®
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Indiana University
Muscle Damage
Made to Measure Compression Garments for Recovery in Rugby Players
Aims To compare the compression pressures exerted by made-to-measure compression garments (CG) with those from standard sized garments To assess the efficacy of custom fitted, high pressure CG for facilitating the recovery of…
- Trial name
- NCT03707470
- Testing
- Custom fitted compression garments (CF), Standard-sized compression garments (SSG)
- Where
- United Kingdom
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Exercise Induced Muscle Damage
Exercise Induced Muscle Damage Post Dance and Sprint Specific Exercise in Females
There is a paucity of studies investigating exercise-induced muscle damage (EIMD) in females and only one in response to dance-type exercise.
- Trial name
- NCT03284450
- Testing
- DPFT, SSRS
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Muscle Damage
Effect of Low-level Laser Therapy on Exercise-induced Muscle Damage
Introduction: The effects of Low Level Laser Therapy (LLLT) on exercise-induced muscular damage have been studied over the last years.
- Trial name
- NCT02493556
- Testing
- LLLT before muscle damage, LLLT after muscle damage
- Where
- Brazil
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Damage Muscle
Muscle Recovery After Omega-3 Supplementation
In recent decades, omega-3 eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been proposed as potential therapeutic agents for minimizing muscle damage induced by eccentric exercise, especially when supplementation…
- Trial name
- NCT07237113
- Testing
- Omega
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencias de la Salud, Universidad de O'Higgins
Muscle Damage, Inflammation
Compared Effect of a Fruit Milk Shake With a Protein-Carbohydrate Supplement on Recovery After Resistance Exercise
The aim of this study is to assess the effect of ingesting a commercial carbohydrate and protein dietary supplement in powder form (P-CHO supplement) or a milk shake with skimmed milk, strawberries and banana (MS), after…
- Conditions
- Muscle Damage, Inflammation, Oxidative Stress, Functional Recovery
- Trial name
- NCT01555775
- Testing
- P-CHO supplement, Fruit Milk Shake
- Where
- Portugal
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Delayed Onset Muscle Soreness, Exercise-induced Muscle Damage
Antioxidant Supplementation and Muscle Recovery From DOMS in Trained Women
This randomized, placebo-controlled, parallel-group trial investigated the effects of combined antioxidant and anti-inflammatory supplementation on delayed onset muscle soreness (DOMS) recovery in trained women.
- Conditions
- Delayed Onset Muscle Soreness, Exercise-induced Muscle Damage, Muscle Recovery
- Trial name
- NCT07877441
- Testing
- Creatine Monohydrate, Omega 3 FA (Fish Oil), N-Acetyl Cysteine (NAC)
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Antonio Molina Lopez
Inflammatory Response, Metabolic Disturbance
Astaxanthin, Exercise Inflammation, Skin Health
Vigorous exercise can stress the body. Consuming special types of diet supplements may help the body recover better from exercise.
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05409092
- Testing
- Astaxanthin
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Muscular Injury
Almond Supplementation and Exercise Recovery
The PURPOSE of this study is to see if eating almonds for four weeks will reduce muscle damage, soreness, and inflammation during several days of recovery from eccentric exercise.
- Trial name
- NCT04958018
- Testing
- Almonds, Snack bars
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Tendon Injuries
GSK1278863 Effects on Eccentric Exercise-Induced Muscle Damage
As per non-clinical studies, prolyl hydroxylase inhibitor GSK1278863 can protect muscle from unaccustomed exercise induced muscle damage and enhance functional muscle repair.
- Trial name
- NCT02231190
- Testing
- GSK1278863
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Skeletal Muscle Damage, Aseptic Inflammation
Redox Status and Immune Function
In this investigation the investigators utilized N-acetylcysteine (NAC) supplementation to enhance reduced glutathione (GSH) stores during an 8-day recovery period from a strenuous eccentric exercise protocol in order to test the…
- Conditions
- Skeletal Muscle Damage, Aseptic Inflammation, Skeletal Muscle Function
- Trial name
- NCT02930031
- Testing
- n-acetylcysteine
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Healthy
EIMD Mechanisms Causing Force Loss
We have hypothesized: 1) Caffeine will increase maximal voluntary strength compared to placebo in undamaged muscle. 2) Caffeine will increase muscle activation compared to placebo in undamaged muscle.
- Trial name
- NCT02125643
- Testing
- Caffeine, Flour
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Inflammatory Response, Metabolic Disturbance
Cranberry Ingestion and Cycling Related Immunity and Inflammation
This is a randomized, crossover clinical trial with 25 male and female cyclists. Study participants will ingest polyphenol-rich cranberry juice or placebo juice for 4 weeks under double-blinded procedures, and then crossover to…
- Conditions
- Inflammatory Response, Metabolic Disturbance, Immune Suppression
- Trial name
- NCT05407701
- Testing
- Cranberry Juice
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Appalachian State University
Supplementation, Sport
HMB and Exercise-induced Muscle Damage
The study aims at assessing the influence of β-hydroxy-β-methylbutyrate (HMB) supplementation (4.0 g/day) supplemented for 7 days in a group of speed-strength trained individuals on lower-body strength performance, selected…
- Conditions
- Supplementation, Sport, Sports Nutrition, Muscle Damage
- Trial name
- NCT04549610
- Testing
- HMB supplementation
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Delayed Onset Muscle Soreness (DOMS), Inflammation
Effects of Immediate and Delayed Repeated Cold Exposure After Physical Exertion
The goal of this clinical trial is to learn if applying cold therapy can reduce swelling, inflammation, and pain after physical activity in adults who experience muscle soreness (Delayed Onset Muscle Soreness, or DOMS).
- Conditions
- Delayed Onset Muscle Soreness (DOMS), Inflammation, Muscle Pain, Muscle Damage
- Trial name
- NCT06813690
- Testing
- Cold Therapy with Axanova Cold Hot Pearls Maxi Pack
- Where
- Switzerland
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Muscle Recovery
Investigating the Efficacy of Low or High Dose Tart Cherry on Recovery From Exercise Induced Muscle Damage and Establishing Its Molecular Mechanisms of Action
To determine the dose-response effects of 10-day tart cherry product consumption (0, 30 ml, and 60 ml) on knee extensor isometric strength 24-h and 48-h after muscle damaging exercise and to elucidate the mechanisms of action for…
- Trial name
- NCT04725149
- Testing
- 500 ml base solution, 500 ml containing 30 ml tart cherry concentrate diluted with water and base solution, 500 ml containing 60 ml tart cherry concentrate diluted with water only
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Muscle Damage
Compression Garments for Recovery in Modern Pentathletes
Aims To assess the efficacy of made to measure, high pressure compression garments (CG) for facilitating the recovery of strength, muscular power, and physiological markers of muscle damage following fencing, when compared a sham…
- Trial name
- NCT03707067
- Testing
- Compression garments
- Where
- 2 sites in United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Exercise Recovery, Exercise-induced Muscle Damage
Effect of Cordyceps Supplementation Timing on Physiological Responses and Aerobic Adaptation in Athletes
Athletes frequently perform high-intensity exercise to improve physical performance and aerobic capacity. However, such training can induce exercise-induced muscle damage, oxidative stress, and inflammatory responses that may…
- Conditions
- Exercise Recovery, Exercise-induced Muscle Damage, Oxidative Stress, Sports Performance
- Trial name
- CORD-RECOV (NCT07664345)
- Testing
- Pre-Exercise Cordyceps Sinensis, Post-Exercise Cordyceps Sinensis
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Surabaya State University
Healthy
Genetic Determinants of Exercise-Induced Muscle Damage (POLYGENDOMUS)
The objective of this study is to evaluate the association between the evolution of plasma CPK levels and genetic polymorphisms, both before the muscle-damaging exercise and at three post-exercise time points.
- Trial name
- POLYGENDOMUS (NCT06740136)
- Testing
- Exercise
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Lille University