Clinical trials: Exercise Prehabilitation
Breast Cancer
Prehabilitation for Breast Cancer Surgery
Prehabilitation for women diagnosed with breast cancer is commonly not part of the clinical pathways as little time (usually a few days) is left between diagnosis and surgery.
- Trial name
- NCT05216302
- Testing
- Group-based Nordic Walking Exercise Program
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Raquel Sebio
Pancreas Adenocarcinoma (MSI-H), Deconditioning
Exercise to Improve Outcomes in Pancreatic Cancer
Pancreatic cancer surgery (Whipple's procedure) is a major operation that can lead to reduced physical fitness, delayed recovery, and difficulty starting chemotherapy after surgery.
- Trial name
- ExO-PanC (NCT07710495)
- Testing
- ExO-PanC Personalised Exercise Programme
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Surrey
Primary Biliary Cholangitis (PBC)
RELIEF: Multimodal Prehabilitation to Treat Fatigue in Patients With Primary Biliary Cholangitis
The implementation of a non-pharmacological multimodal intervention program-including physical exercise, nutritional counseling, and psychological support-is expected to improve fatigue in patients with primary biliary…
- Trial name
- RELIEF (NCT07161245)
- Testing
- Multimodal prehabilitation, standard of care
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Lung Cancer
A Prehabilitation Program to Boost Postoperative Functional Capacity in Surgical Lung Cancer Patients
This research study is evaluating a prehabiliation intervention designed to improve postoperative functional capacity (measured by 6-minure walking distance) in individuals undergoing lung resection for cancer.
- Trial name
- NCT04826835
- Testing
- Prehabilitation intervention, Health education control
- Where
- Hong Kong
- Volunteers
- 198 people
- Sponsor
- The University of Hong Kong
Surgical Patients, Preoperative Care
Prehab for Surgery
Surgical prehabilitation is the process of enhancing one's physical function and mental capacity to enable him/or her to withstand the stressor of surgery.
- Trial name
- NCT04155346
- Testing
- Exercise, nutritional optimization, and psychoeducation
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- University of Toronto
Colorectal Neoplasms, Aged
Exercise Program for Colorectal Older Patients
The Exercise for COlorectal OLder patients (ECOOL program) is randomized controlled trial to assess the effects of an exercise program on physical function and health-related quality of life of patients 75 years and older with…
- Trial name
- ECOOL (NCT05448846)
- Testing
- Enhanced Recovery After Surgery, Home-based multicomponent exercise program (EXE)
- Where
- Spain
- Volunteers
- 252 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Colorectal Cancer, Colorectal Liver Metastasis
Prehabilitation in Liver Surgery
Each year in the UK around 1500 patients undergo surgery for bowel cancer that has spread to the liver. This is major surgery that offers a chance of cure, but can be associated with complications.
- Conditions
- Colorectal Cancer, Colorectal Liver Metastasis, Liver Surgery, Exercise Intervention
- Trial name
- NCT01523353
- Testing
- Exercise Intervention
- Where
- United Kingdom
- Volunteers
- 37 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Breast Cancer, Frailty
Multicomponent Prehabilitation in Older Adults With Breast Cancer
Older adults with breast cancer frequently present with frailty, decreased functional reserve, and increased risk of postoperative complications.
- Conditions
- Breast Cancer, Frailty, Sarcopenia, Aging
- Trial name
- PREHAB-BC65 (NCT07531836)
- Testing
- Home-based Multicomponent Prehabilitation (Vivifrail), Supervised Multicomponent Prehabilitation, Comprehensive Geriatric Assessment and Optimization
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Fundacion Miguel Servet
Inspiratory Muscle Training
Inspiratory Muscle Training in Lung Transplant Candidates
Recovery after lung transplantation (LTx) may be complicated by prolonged mechanical ventilation (MV) and protracted intensive care unit (ICU) stay leading to immobilization and impaired health-related quality of life (HRQoL).
- Trial name
- NCT06370832
- Testing
- IMT and exercise training group
- Where
- 4 sites in Canada
- Volunteers
- 90 people
- Sponsor
- University Health Network, Toronto
Hepatobiliary Cancer, Cholangiocarcinoma
Senior Adult Hepatobiliary Prehab Study
The purpose of the study is to evaluate an exercise program for individuals with hepatobiliary cancer planning for surgery.
- Conditions
- Hepatobiliary Cancer, Cholangiocarcinoma, Liver Metastases
- Trial name
- NCT05921552
- Testing
- Resistance Training, Aerobic Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Aortic Stenosis, Severe
The CardioFit Trial: Exercise Training Before Aortic Valve Surgery
The CardioFit Trial: The feasibility, safety and tolerability of an exercise training programme in patients with severe aortic stenosis prior to aortic valve replacement surgery: A feasibility trial To investigate if a Structured…
- Trial name
- CardioFit (NCT06818110)
- Testing
- Exercise
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Colorectal Cancer
Enhancing Fitness With Preoperative Exercise in Colorectal Cancer Surgery
This study examines whether a home-based telephone-guided preoperative exercise programme is feasible and effective in improving cardiorespiratory fitness in patients with colorectal cancer who are high risk due to their existing…
- Trial name
- EFEx (NCT03336229)
- Testing
- Exercise intervention
- Where
- 4 sites in United Kingdom
- Volunteers
- 72 people
- Sponsor
- NHS Greater Glasgow and Clyde
Osteoarthritis, Knee
Prehabilitation Using Aquatic Exercise
With aging population, total knee arthroplasty is performed with increasing frequency. Although the surgery is successful in general, significant number of patients suffers persistent pain and disability.
- Trial name
- NCT02773745
- Testing
- Aquatic Prehab
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sarcopenia, Exercise Intolerance
Prehabilitation for Cardiac Surgery in Patients With Reduced Exercise Tolerance
Among patients awaiting cardiac surgery, a significant proportion are patients with severe angina, heart failure (HF) and peripheral atherosclerosis.
- Conditions
- Sarcopenia, Exercise Intolerance, Heart Failure, Peripheral Artery Disease
- Trial name
- NCT04545268
- Testing
- Neuromuscular electrical stimulation (NMES), Transcutaneous electrical stimulation
- Where
- Russia
- Volunteers
- 60 people
- Sponsor
- Research Institute for Complex Problems of Cardiovascular Diseases, Russia
Head and Neck Carcinoma
An Exercise Prehabilitation Intervention for Improving Mobility and Recovery Outcomes in Patients Undergoing Head and Neck Cancer Surgery
This clinical trial evaluates a prehabilitation exercise intervention for improving mobility and recovery outcomes in patients undergoing surgery for head and neck cancer.
- Trial name
- NCT06079697
- Testing
- Electronic Health Record Review, Exercise Intervention, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- OHSU Knight Cancer Institute
Recurrent Multiple Myeloma, Refractory Multiple Myeloma
Prehabilitation With Aerobic and Resistance Exercise for Improving Physical Fitness and Quality of Life Outcomes in Older Patients Undergoing CAR-T Therapy for Relapsed or Refractory Multiple Myeloma
This clinical trial evaluates whether prehabilitation with aerobic and resistance exercise improves physical fitness and quality of life outcomes in older patients planning to undergo chimeric antigen receptor (CAR)-T therapy for…
- Trial name
- NCT07045727
- Testing
- Accelerometry, Aerobic Exercise, Biospecimen Collection
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Knee Osteoarthritis
Pre-Operative Exercise Therapy and Patient Education Before Total Knee Replacement
The goal of this multi-center randomized controlled trial is to investigate the effect of pre-operative exercise therapy and education for patients awaiting knee replacement surgery on subjective knee function, patient…
- Trial name
- PROTEKT (NCT06290336)
- Testing
- Pre-operative exercise therapy and education, Standardized pre-operative information session
- Where
- Sweden
- Volunteers
- 110 people
- Sponsor
- Linkoeping University
Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity
Prehabilitation in Childhood Soft Tissue or Bone Sarcomas
This study aims to investigate the feasibility of a prehabilitative training intervention. The intervention includes specific strength and balance exercises during neoadjuvant chemotherapy with children and adolescents diagnosed…
- Conditions
- Soft Tissue Sarcoma of the Lower Extremity, Bone Tumor of the Lower Extremity, Childhood and Adolescent Cancer
- Trial name
- Prehab4Kids (NCT06743958)
- Testing
- Exercise intervention
- Where
- 2 sites in Germany
- Volunteers
- 16 people
- Sponsor
- Technical University of Munich
Postoperative Pain, Postoperative Nausea and Vomiting
The Effects of Preoperative Physical Activities on Surgeries
Recommendation is strong on physical activity (PA) in the prehabilitation of Enhanced Recovery After Surgery (ERAS) for various types of surgeries. The evidence is however weak regarding ERAS protocols.
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Prehabilitation, Physical Activities
- Trial name
- NCT04739787
- Volunteers
- 5,500 people
- Sponsor
- Chiayi Christian Hospital
Breast Cancer, Breast Neoplasms
Impact of Prehabilitation and Comprehensive Follow-up in Women With Breast Cancer
Breast cancer (BC) is the most common cancer among women worldwide. Cancer treatments are associated with numerous adverse events that reduce patients' functionality and alter their clinical and molecular profiles.
- Trial name
- PREACT (NCT07467824)
- Testing
- Prehabilitation: Exercise and nutrition
- Where
- 2 sites in Spain
- Volunteers
- 66 people
- Sponsor
- European University Miguel de Cervantes