Clinical trials: Exercise Pulmonary Hypertension
Pulmonary Arterial Hypertension, Congenital Heart Disease
Bosentan In Exercise Induced Pulmonary Arterial Hypertension in CongenitaL Heart diseasE
SUMMARY Rationale: Pulmonary arterial hypertension (PAH) can be a rapidly progressive disorder and is associated with a high mortality rate, despite medical intervention.
- Trial name
- BICYCLE (NCT01827059)
- Testing
- Bosentan
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Glaucoma, Depression
Impact of Breathing Exercises and Meditation on Improving Quality of Life in Glaucoma Patients
Glaucoma is a chronic disease that causes loss of vision and potentially blindness as a result of optic nerve damage, often due to increased intraocular pressure.
- Conditions
- Glaucoma, Depression, Anxiety, Quality of Life
- Trial name
- NCT05960513
- Testing
- Breathing Exercises followed by Meditation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pulmonary Disease, Chronic Obstructive, Hypertension, Pulmonary
Aerobic Interval Training in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Hypoxemia
Patients with severe Chronic Obstructive Pulmonary Disease (COPD) and low oxygen levels in the blood are at risk of developing pulmonary hypertension and strain on the right side of the heart, both of which are known to increase…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Hypertension, Pulmonary, Hypoxia
- Trial name
- NCT03092622
- Testing
- Exercise
- Where
- Norway
- Volunteers
- 16 people
- Sponsor
- Norwegian University of Science and Technology
Pulmonary Hypertension
Remote Exercise Testing in Patients With Pulmonary Hypertension
The investigators plan to investigate the feasibility and validity of tests of exercise capacity, when these are performed in hospital and at home, by patients who are diagnosed with pulmonary hypertension.
- Trial name
- NCT05299463
- Testing
- Exercise Testing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Golden Jubilee National Hospital
Hypertension, Pulmonary
The Exercise Capacity and Quality of Life in the Patients With IPAH and Secondary PH
Pulmonary hypertension (PH) is a progressive disease with high mortality rate, but due to the development of drugs, the prognosis of the disease has improved.
- Trial name
- NCT02647060
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- National Taiwan University Hospital
Chronic Thromboembolic Pulmonary Hypertension
Exercise Therapy After Pulmonary Thromboendarterectomy or Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension
This study is being completed to determine the feasibility and acceptability of completing a home-based, structured, low-to-moderate intensity exercise training program in chronic thromboembolic pulmonary hypertension (CTEPH)…
- Trial name
- EXPECT-PH (NCT05693779)
- Testing
- Home exercise training
- Sponsor
- University of Michigan
Pulmonary Hypertension
Dead Space Evaluation in Pulmonary Hypertension
Aim of the study is to evaluate the role of chemoreceptor activity and ventilation perfusion mismatch on the genesis of exercise induced hyperventilation in Pulmonary hypertension patients.
- Trial name
- NCT02892981
- Testing
- cardiopulmonary exercise test,hypoxia and hypercapnia test
- Volunteers
- 18 people
- Sponsor
- Centro Cardiologico Monzino
Pulmonary Arterial Hypertension
Effect of iNO on Invasively Derived Pulmonary Pressures in Patients With PAH
Pulmonary hypertension is characterized by an increase in the pressures in the blood supply to the lungs greater than a mean pressure of 25mmHg and a concomitant increase in overall pulmonary vascular resistance (PVR).
- Trial name
- NCT02734953
- Testing
- Nitric Oxide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Idiopathic Pulmonary Fibrosis, Pulmonary Hypertension
Effects of Inhaled Treprostinil Sodium for the Treatment of Pulmonary Hypertension Associated With Idiopathic Pulmonary Fibrosis
The purpose of this study is to establish single-dose tolerability of inhaled treprostinil sodium in idiopathic pulmonary fibrosis (IPF) patients with pulmonary hypertension, and to explore the acute hemodynamic effects over a…
- Trial name
- NCT00703339
- Testing
- Treprostinil sodium for inhalation
- Where
- 6 sites in United States
- Volunteers
- 1 people
- Sponsor
- Lung Biotechnology PBC
Pulmonary Arterial Hypertension
The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension Study
The purpose of this study is to find out if spironolactone added to ambrisentan for Pulmonary Arterial Hypertension (PAH) will increase exercise capacity.
- Trial name
- NCT02253394
- Testing
- Ambrisentan plus Spironolactone
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Pulmonary Fibrosis, Pulmonary Hypertension
Inhaled Iloprost in Adults With Abnormal Pulmonary Pressure and Associated With Idiopathic Pulmonary Fibrosis
The primary purpose of this study is to determine whether iloprost inhalation solution is safe in subjects with idiopathic pulmonary fibrosis (IPF) and elevated pulmonary arterial pressure.
- Trial name
- NCT00109681
- Testing
- Iloprost Inhalation Solution (Ventavis)
- Where
- 17 sites in United States
- Volunteers
- 50 people
- Sponsor
- Actelion
Pulmonary Arterial Hypertension
Effects of Physical Training on Vascular Function as a Therapeutic Target in Pulmonary Hypertension
The role of physical training in the treatment of pulmonary arterial hypertension (PAH) is controversial. The aim of the project is to evaluate the effect of physical training on markers of endothelial function and integrity and…
- Trial name
- NCT03550729
- Testing
- Endurance training
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Clinic of Barcelona
Pulmonary Hypertension
Acute Exposure to High Altitude on Symptoms
Randomized crossover Trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (2500m above sea level) in altitude related symptoms
- Trial name
- NCT03593005
- Testing
- Assessment at Low Altitude (470m above sea level), Exposure to High Altitude (2500m above sea level)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Pulmonary Hypertension
Acute Exposure to High Altitude on Heart Rate and Ventilation During Exercise
Randomized crossover trial in patients with Pulmonary Hypertension (PAH, CTEPH) to assess the acute response to High Altitude (Säntis; 2500m above sea level) on heart rate and Ventilation changes under exercise.
- Trial name
- NCT03593096
- Testing
- Assessment at Low Altitude (470m above sea level), Exposure to High Altitude (2500m above sea level)
- Where
- Switzerland
- Volunteers
- 28 people
- Sponsor
- University of Zurich
Pulmonary Arterial Hypertension, Insulin Resistance
Pulmonary Arterial Hypertension Improvement With Nutrition and Exercise (PHINE)
The purpose of this study is to investigate the extent to which diet and exercise may improve PAH through the modulation of insulin sensitivity.
- Trial name
- NCT03288025
- Testing
- Nutrition and Exercise
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- The Cleveland Clinic
Heart Failure, Pulmonary Hypertension
Exercise Training to Improve Cardiopulmonary Hemodynamics in Heart Failure Patients
This research study is being done to find out if exercise therapy can help improve the heart function, overall health, and quality of life of patients with pulmonary hypertension caused by heart failure.
- Trial name
- NCT04909008
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Hypertension, Pulmonary
Effects of Normobaric Hypoxia During Exercise in Patients With Pulmonary Hypertension With/Without Sildenafil
To study the effect of acute normobaric hypoxia during exercise in patients with pulmonary hypertension with/without Sildenafil
- Trial name
- HEXAS (NCT04704440)
- Testing
- Normobaric hypoxia (FiO2 15%), Normobaric hypoxia (FiO2 15%) under Sildenafil
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- University of Zurich
Pulmonary Hypertension, Interstitial Lung Disease
The Benefits of Home Exercise in Pulmonary Hypertension Interstitial Lung Disease
This study evaluates the effects of a structured home exercise program in participants with pulmonary hypertension associated with interstitial lung disease.
- Trial name
- NCT07561034
- Testing
- Home Exercise Program, Aerobic Plus Strength Training, Home Exercise Program, Aerobic Only
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
High Altitude, Healthy
Assessment of Six-minute Walking Distance Between Sea Level LA vs. High Altitude HA After Re-ascent in Healthy Individuals
To study the effect of a re-ascent after a one-week stay at sea level (after prior descent from 2850m) to high altitude (Quito Ecuador: 2850m) on six-minute walking distance and other scores in healthy individuals, who live…
- Conditions
- High Altitude, Healthy, Healthy Adult, Six-minute Walk Test
- Trial name
- NCT07797088
- Testing
- Re-Ascent sea level to 2850m
- Where
- Switzerland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Silvia Ulrich Somaini
Heart Failure With Preserved Ejection Fraction, Pulmonary Hypertension
Exercise Right Ventricular Coupling in HFpEF
The investigators aim to evaluate the feasibility and prognostic value of right ventricular-arterial coupling (RVAC) during exercise in patients with HFpEF-PH using a hybrid technique of real-time CMRderived volume measures and…
- Trial name
- ENDURE (NCT05731466)
- Testing
- CardioMems HF System
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven