Clinical trials: Exercise Sensitivity
Insulin Sensitivity, Glucose Intolerance
Effects of Progressive Negative Energy Balance on Glucose Tolerance, Insulin Sensitivity, and Beta-cell Function
Type 2 diabetes results from a combination of peripheral insulin resistance and beta-cell dysfunction, and manifests as fasting and postprandial hyperglycemia.
- Conditions
- Insulin Sensitivity, Glucose Intolerance, Insulin Resistance, Energy Supply; Deficiency
- Trial name
- NCT03264001
- Testing
- Negative energy balance
- Where
- Singapore
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Singapore Institute of Food and Biotechnology Innovation
Allergic Rhinitis
The Effect of Exercises on Physiological Changes and Clinical Symptoms in Allergic Rhinitis Patients
1. Moderate exercise training decrease cytokine response and rhinitis symptoms in patients with allergic rhinitis 2. Moderate exercise training combined with vitamin C supplementation decrease cytokine response and rhinitis…
- Trial name
- NCT02123914
- Testing
- Aerobic exercise with Vit. C, Aerobic exercise, No exercise
- Where
- Thailand
- Volunteers
- 27 people
- Sponsor
- Chulalongkorn University
Bariatric Surgery Candidate
Exercise Training Study Before Bariatric Surgery
The goal of this clinical trial is to figure out if 8 weeks of walking exercise before bariatric surgery improves risk factors for diabetes and other markers of health.
- Trial name
- BaSE (NCT06274606)
- Testing
- Exercise Group
- Where
- United States
- Sponsor
- University of Virginia
Pre-diabetes, Overweight and Obesity
Timing Exercise Training as Strategy to Improve Insulin Sensitivity and Substrate Metabolism in Men and Woman With Pre-diabetes
n a retrospective analysis of an exercise training program performed either in the morning or afternoon, we found that the afternoon training group improved their peripheral insulin sensitivity and fasting plasma glucose levels…
- Trial name
- Timed Training (NCT06014684)
- Testing
- Timing of exercise
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Insulin Resistance
Mechanisms of Insulin Resistance and Exercise in South Asians
This study determines the effect of aerobic and resistance exercise training on whole-body and skeletal muscle insulin sensitivity in south Asians and evaluate the mechanisms which contribute to improvements in insulin…
- Trial name
- NCT04007926
- Testing
- Aerobic exercise programme, Resistance exercise programme
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Glasgow
Asthma in Children, Telerehabilitation
COVID-19 Pandemic Asthma Child Telerehabilitation Yoga
In our study, yoga asana and pranayama practices, which will be applied by video call from computer or phone, will be advantageous in terms of time, transportation and access to asthmatic children whose anxiety and anxiety levels…
- Conditions
- Asthma in Children, Telerehabilitation, Yoga
- Trial name
- NCT05684926
- Testing
- Telerehabilitation yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Bartın Unıversity
Coronary Artery Disease
Exercise-induced High-sensitivity Troponin Levels as a Predictor for Obstructive Coronary Artery Disease
1. To compare hs-TnT levels after a cardiac stress test in patients with vs. patients without CAD 2. To assess the level of post-exercise hs-TnT predicting CAD (using ROC-analysis) 3.
- Trial name
- EUROCAD (NCT02626806)
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cholinergic Urticaria
Cholinergic Urticaria - Efficacy of Dupilumab
The purpose of this study is to assess the efficacy in reducing disease activity and safety of Dupilumab in adult patients with cholinergic urticarial (CholU) who are symptomatic despite H1-antihistamine treatment (licensed dose).
- Trial name
- CHED (NCT03749148)
- Testing
- Dupilumab
- Where
- 8 sites in Germany
- Volunteers
- 48 people
- Sponsor
- Charite University, Berlin, Germany
Asthma, Exercise Induced
Role of Leukotrienes and Adenosine in Hyperpnea-induced Bronchospasm
This research is being conducted to help us better understand what causes exercise induced asthma. The investigators hypothesize that two types of chemicals, cysteinyl leukotrienes and adenosine, play an important role.
- Trial name
- NCT00710255
- Testing
- Hyperpnea challenge
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Vermont
Bronchospasm, Exercise-Induced
Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
This will be a double-blind placebo-controlled study in which we plan to study 40 competitive endurance athletes. We will conduct an exercise test to evaluate maximal oxygen uptake and 2 exercise challenge tests to provoke EIA.
- Trial name
- STAMINA (NCT01691079)
- Testing
- ipratropium bromide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Osteoarthritis, Knee, Pain
Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis
Osteoarthritis (OA) in the knee is characterized by chronic inflammatory pain that is not necessarily related to the amount of joint damage.
- Conditions
- Osteoarthritis, Knee, Pain, Physical Activity, Mitochondrial Pathology
- Trial name
- NCT03344913
- Testing
- Walking
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Pain, Physical Activity
Influence of Expectations on Change in Pain Perception After a 3 Min Wallsquat Exercise.
The purpose of this study is to investigate how expectations induced by information given prior to exercise influence the magnitude of exercise-induced hypoalgesia after a 3 min wallsquat exercise in healthy subjects.
- Trial name
- NCT03678662
- Testing
- Hypoalgesia expectation, Hyperalgesia expectation, Neutral
- Where
- Denmark
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Persian Gulf Syndrome
Treatment Study of Carnosine Versus Placebo in Gulf War Illness (GWI)
The purpose of this study is to perform a randomized double-blind, placebo-controlled, 12 week study of the effects of carnosine on cognitive, psychometric, autonomic, and muscle strength outcomes in 100 GWI subjects.
- Trial name
- NCT00810368
- Testing
- Carnosine
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Georgetown University
Asthma, Child
Buteyko Method for Children With Asthma
This study has the aim to assess the effectiveness of the Buteyko method as an adjunct therapy in the treatment of children with asthma.
- Conditions
- Asthma, Child, Breathing Exercises
- Trial name
- NCT02720380
- Testing
- Buteyko, Asthma education
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal do Rio Grande do Norte
Exercise Induced Asthma, Exercise Induced Pharyngeal Collapse
Diagnostics and Quality of Life With EIA and EILO
The purpose of this study is to investigate the quality of life of subjects suffering from dyspnoea while exercising and quantify the number of diagnoses of Exercise induced Asthma (EIA) and Exercise induced laryngeal obstruction…
- Trial name
- NCT03550456
- Testing
- ECC, ECC with CLE, Speech therapy
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- Johann Wolfgang Goethe University Hospital
Obesity, Insulin Resistance
Race, Menopause and Metabolism After Exercise and Diet
The purpose of this study is to test the hypotheses that there are ethnic and genetic differences in the mechanisms and magnitude by which hypocaloric weight loss and aerobic exercise affect body composition, glucose, lipid…
- Conditions
- Obesity, Insulin Resistance, Sedentary Lifestyle
- Trial name
- NCT00882141
- Testing
- Diet modification, Aerobic exercise
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Obesity, Obesity; Endocrine
Acute and Chronic Metabolic Flexibility in Individuals Living With Obesity: The i-FLEX Study
Regular exercise is a cornerstone in the prevention and the management of cardio-metabolic risk factors. Some of the beneficial effect of exercise training occurs through metabolic flexibility' enhancement.
- Conditions
- Obesity, Obesity; Endocrine, Insulin Sensitivity, Exercise
- Trial name
- i-FLEX (NCT03527446)
- Testing
- Sprint Interval Training
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of New Brunswick