Clinical trials: Exercise-induced Asthma
Exercise-induced Bronchospasm
Mechanisms of Exercise-induced Bronchospasm
The term exercise-induced bronchospasm (EIB) describes acute, transient airway narrowing that occurs during, and most often after, exercise.
- Trial name
- NCT00701025
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Exercise Induced Laryngeal Obstruction, Asthma in Children
Prevalence of EILO Among Children With Asthma
The goal of this cross-sectional study is to investigate the prevalence of Exercise Induced Laryngeal Obstruction (EILO) in children with asthma.
- Conditions
- Exercise Induced Laryngeal Obstruction, Asthma in Children, Exercise-Induced Bronchospasm, Exercise-Induced Bronchoconstriction
- Trial name
- NCT06480084
- Testing
- Continuous Laryngoscopy during Exercise Test (CLE test)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Medisch Spectrum Twente
Asthma
Role of Airway Hyperresponsiveness on Performance in Elite Swimmers.
The prevalence of airway hyperresponsiveness (AHR) is very high in elite swimmers, reaching 80% in certain studies. Repeated Chlorine-derivatives exposure may be a major causative factor for its development.
- Trial name
- NCT00876135
- Testing
- Ventolin
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- Laval University
Exercise Induced Asthma
Comparing Symbicort® As-Needed or Bricanyl As-Needed or Pulmicort® Once Daily + Bricanyl As-Needed in Asthma Patients
1. The primary objective of this study is: To evaluate the magnitude of the protective effect of the combination of budesonide and formoterol on an as-needed basis compared to the use of terbutaline as-needed on exercise induced…
- Trial name
- MIA (NCT00989833)
- Testing
- budesonide, terbutaline, budesonide/formoterol
- Where
- 10 sites in Norway, Sweden
- Volunteers
- 66 people
- Sponsor
- AstraZeneca
Exercise-Induced Asthma
Study of Oglemilast for the Prevention of Asthma.
The purpose of this study is to determine whether it is effective in the treatment of exercise-induced asthma and investigate the safety of oglemilast.
- Trial name
- NCT00322283
- Testing
- Oglemilast
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Forest Laboratories
Asthma, Exercise-Induced
The Effect of Benralizumab on Exercise-induced Bronchoconstriction
Severe asthma affects 5-10% of more than 300 million asthmatics. Ten to twenty percent of individuals suffering from asthma do not respond well to current treatment due to the complexity of the different mechanisms underlying…
- Trial name
- NCT03327701
- Testing
- Benralizumab
- Volunteers
- 40 people
- Sponsor
- Louis-Philippe Boulet
Asthma, Exercise-induced
Exercise Induced Bronchoconstriction (0476-359)
Exercise-induced bronchoconstriction (EIB) is a condition where airways tighten when you exercise and may cause coughing, wheezing, or shortness of breath.
- Trial name
- NCT00664937
- Testing
- montelukast sodium
- Volunteers
- 24 people
- Sponsor
- Organon and Co
Asthma, Exercise-Induced Bronchoconstriction
Effect of a Component of Fish Oil on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
The primary aim of this study will be to evaluate the effects of Lyprinol® supplementation on airway inflammation and the bronchoconstrictor response to dry air hyperpnea in individuals with asthma.
- Trial name
- NCT01504646
- Testing
- Lyprinol
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Exercise Induced Asthma
Study to Assess Safety and Efficacy of Oral Senicapoc Administration on Exercise-induced Asthma
The purpose of this study is to determine whether 4 weeks of dosing with senicapoc alleviates exercise induced asthma symptoms.
- Trial name
- NCT00861185
- Testing
- senicapoc
- Where
- 9 sites in United States
- Volunteers
- 69 people
- Sponsor
- Icagen
Asthma
Effect of Different Anti-Asthmatic Treatments on Lung Function and on Exercise-Induced Bronchoconstriction in Children With Asthma
The present study was conducted to determine the effects of four week treatment with budesonide, montelukast, budesonide with montelukast and budesonide with formoterol in children with atopic asthma on lung function: forced…
- Trial name
- NCT00490243
- Testing
- budesonide and montelukast, budesonide and formoterol, montelukast
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Lodz
Exercise-induced Bronchospasm
Efficacy Study of Single-Dose Levalbuterol Tartrate HFA MDI Vs Placebo in Subjects 18 Years and Older With EIB
To determine if administration of levalbuterol tartrate HFA MDI in subjects with EIB will be effective in the prevention of EIB and be safe and well-tolerated.
- Trial name
- NCT00268723
- Testing
- Levalbuterol tartrate HFA MDI
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Sumitomo Pharma America, Inc.
Asthma, Exercise-Induced, Asthma
Do Heat and Moisture Exchange Mask Reduce EIB and Cough Severity in Asthma
The overall aim of this study is to determine if face masks that can warm and humidify air can improve overall asthma control and markers of airway health during exercise in cold dry environments.
- Trial name
- NCT04302610
- Testing
- Heat and Moisture Exchange mask (ColdAvenger® expedition balaclava, USA,
- Volunteers
- 26 people
- Sponsor
- University of Kent
Asthma in Children, Obesity, Childhood
Reducing Exercise-induced Bronchoconstriction in Children With Asthma and Obesity
Guidelines from the American Thoracic Society strongly recommend interval warm-up exercise before planned exercise to reduce exercise-induced bronchoconstriction severity.
- Conditions
- Asthma in Children, Obesity, Childhood, Exercise Induced Bronchospasm
- Trial name
- NCT03586544
- Testing
- Albuterol Sulfate, Interval Warm-up exercise
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Bronchospasm, Activity/Exercise Induced Bronchospasm
A Study Measuring Asthma Control In Pediatric And Adolescent Subjects Whose Asthma Is Worsened By Activity Or Exercise
During this study, your child will need to attend up to 5 office visits and maintain regular telephone contact with the clinic. Certain office visits will include physical exams, medical history review, exercise challenge test…
- Trial name
- NCT00118690
- Testing
- Fluticasone propionate/salmeterol
- Where
- 51 sites in United States
- Volunteers
- 227 people
- Sponsor
- GlaxoSmithKline
Asthma in Children, Exercise Induced Asthma
The Rainbow Study - the Effect of Feedback on Asthmatic Symptom Perception
Asthma is a common childhood disease that is characterized by chronic airway inflammation and episodic expiratory airflow obstruction.
- Trial name
- NCT06702735
- Testing
- Rainbow tool, Feedback
- Where
- Netherlands
- Volunteers
- 39 people
- Sponsor
- Medisch Spectrum Twente
Asthma
Effect of Fish Oil and Vitamin C on Exercise-Induced Bronchoconstriction and Airway Inflammation in Asthma
Combining fish oil and vitamin C supplementation will provide a greater anti-inflammatory effect against developing exercise-induced bronchoconstriction (EIB) than either nutritional supplement alone.
- Trial name
- NCT01057615
- Testing
- Fish Oil, Ascorbic Acid
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Indiana University
Exercise-induced Bronchospasm
Comparison of Two Bronchodilator Inhalers in Adolescents and Adults With Exercise-Induced Asthma
This study was designed to examine the effectiveness of two bronchodilator inhalers in patients who have exercise-induced asthma.
- Trial name
- NCT00085774
- Testing
- albuterol aerosol by HFA MDI, albuterol aerosol by HFA BOI
- Where
- 3 sites in United States
- Volunteers
- 24 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Exercise Induced Asthma
Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma
The purpose of this study is to find out if Symbicort® (budesonide/formoterol), a new combination asthma medication, is more effective than budesonide alone in controlling exercise induced asthma.
- Trial name
- NCT01070888
- Testing
- Budesonide/Formoterol, Budesonide
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Boston Children's Hospital
Bronchospasm, Exercise-Induced
Effectiveness of Ipratropium Bromide in Preventing Exercise-induced Bronchoconstriction in Athletes
This will be a double-blind placebo-controlled study in which we plan to study 40 competitive endurance athletes. We will conduct an exercise test to evaluate maximal oxygen uptake and 2 exercise challenge tests to provoke EIA.
- Trial name
- STAMINA (NCT01691079)
- Testing
- ipratropium bromide
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Asthma, Bronchoconstriction
Dose Response Study of Levalbuterol in the Prevention of Exercise Induced Bronchoconstriction Compared to Racemic Albuterol
The purpose of this study is to investigate, using an exercise challenge approach, the dose response of levalbuterol HFA MDI in adolescent and adult subjects with asthma
- Trial name
- NCT00685425
- Testing
- Levalbuterol HFA MDI, Racemic Albuterol
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Sumitomo Pharma America, Inc.