Clinical trials: Exercises
Obesity, Activity, Motor
Healthy Juntos Pilot Study
The purpose of the study is to assess the feasibility, acceptability, and preliminary effects of a digital (web and mobile phone-based) program to improve physical activity levels and quality dietary intake among Hispanic…
- Conditions
- Obesity, Activity, Motor, Diet, Healthy, Sedentary Behavior
- Trial name
- NCT03986190
- Testing
- Healthy Juntos
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Miami
Heart Failure, Congestive
Evaluation of the Safety and Effectiveness of the OPTIMIZER System in Subjects With Heart Failure: FIX-HF-5
The purpose of this study is to determine whether treatment with the OPTIMIZER System is safe and effective in patients with moderate to severe heart failure symptoms.
- Trial name
- NCT00112125
- Testing
- OPTIMIZER System
- Where
- United States
- Volunteers
- 428 people
- Sponsor
- Impulse Dynamics
Type 2 Diabetes Mellitus
Comparative Study to Evaluate Efficacy and Safety When Metformin Hydrochloride 500 mg Once Daily is Added on to SYR-322 25 mg in Type 2 Diabetic Patients With Inadequate Glycemic Control Despite Treatment With SYR-322 25 mg in Addition to Diet and Exercise Therapy
The purpose of this study was to evaluate the efficacy and safety of 24-week treatment with metformin hydrochloride 500 mg once daily added on to alogliptin (SYR-322) 25 mg in type 2 diabetic patients with inadequate glycemic…
- Trial name
- NCT02068443
- Testing
- Alogliptin, Metformin hydrochloride
- Where
- 27 sites in Japan
- Volunteers
- 374 people
- Sponsor
- Takeda
Knee Osteoarthritis
Physical Therapy Versus Internet-Based Exercise Training for Patients With Knee Osteoarthritis
The purpose of this study is to examine the effectiveness of standard physical therapy and an internet-based exercise program for people with knee osteoarthritis (OA).
- Trial name
- PATH-IN (NCT02312713)
- Testing
- Internet Based Exercise Training, Physical Therapy
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of North Carolina, Chapel Hill
Major Depressive Disorder
CBT+ for Depression
This study investigates the effects of a novel intervention approach, intentionally sequencing aerobic exercise immediately prior to therapy sessions (i.e., cognitive behavioral therapy [CBT]) to determine its effects on both…
- Trial name
- CBT+ (NCT06001346)
- Testing
- ActiveCBT, CalmCBT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Mild Cognitive Impairment
Pioglitazone Or Exercise to Treat Mild Cognitive Impairment (MCI)
The purpose of this study is to investigate novel treatments to delay progression to dementia in patients with mild cognitive impairment (MCI) and metabolic syndrome (MS).
- Trial name
- POEM (NCT00736996)
- Testing
- Pioglitazone, Endurance Exercise Training
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Aging
Resveratrol and Exercise to Treat Functional Limitations in Late Life
The purpose of this research study is to evaluate the effects of combining physical exercise with a resveratrol supplementation on the physical function of older adults.
- Trial name
- NCT02523274
- Testing
- Resveratrol, Exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Dementia, Alzheimer's Disease
Preventing Loss of Independence Through Exercise (PLIE) in Persons With Dementia
Nearly 1 in 10 older Veterans have dementia, which is a devastating condition that leads to a progressive loss of independence and functional status. Currently available dementia medications do not alter the disease course.
- Trial name
- PLIE-VA (NCT02350127)
- Testing
- Preventing Loss of Independence through Exercise (PLIE), Usual Care
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- VA Office of Research and Development
Amputation Stumps, Diabetes Mellitus
Evidence Based Amputee Rehabilitation (EBAR) Program
The purpose of this study is to determine if an evidence based exercise intervention improves the functional mobility of diabetic amputees (single lower leg amputation) who have already completed standard rehabilitation and…
- Trial name
- EBAR (NCT00126126)
- Testing
- EBAR Program
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- US Department of Veterans Affairs
Physical Activity
Peer Empowerment Program for Physical Activity in Low Income and Minority Seniors
Older adults are the least active population group in the US. Yet, research has shown that an increase in physical activity (PA) can have immediate and profound effects on cardiovascular health.
- Trial name
- PEP4PA (NCT02405325)
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Overweight
Exercise and Phytoestrogens: Effect on Factors Predisposing to Cardiovascular Disease(CVD) in Postmenopausal Women
Menopause is characterized by a decrease of estrogen and progesterone levels and is associated with various changes in body composition, including an accumulation of total fat mass, a relocation of adiposity to the abdomen…
- Trial name
- NCT01048606
- Testing
- Phytoestrogens without exercise, Phytoestrogens + exercise
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- Université de Sherbrooke
Exercise Training, Hemodynamic Response
The Impact of Blood Flow Restriction (BFR) on Exercise and Hemodynamic Responses
The impact of blood flow restriction (BFR) on exercise and hemodynamic responses will be studied. The use of BFR will be studied during yoga and low-intensity aerobic exercise in healthy subjects with no history of chronic…
- Trial name
- NCT03540147
- Testing
- Hokanson Cuffs, BStrong Bands
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Autism Spectrum Disorder
Effect of Virtual Reality-based Training on Balance and Walking in Youth With Autism Spectrum Disorder
The goal of this clinical trial is to assess the effect of short-term (3 days/week for 2 weeks) Virtual Reality (VR) active video gaming intervention on static and dynamic balance, versus traditional balance training exercises…
- Trial name
- NCT06023563
- Testing
- Virtual reality active video gaming using Nintendo switch sports, Standard physical therapy balance exercises
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Indiana University
COPD, Emphysema
The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD
COPD currently afflicts 24 million US residents; the prevalence of COPD is high among Veterans. Persons with COPD have significant functional disability as a result of the disease.
- Conditions
- COPD, Emphysema, Chronic Bronchitis
- Trial name
- WEB (NCT02099799)
- Testing
- Pedometer and Website
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- VA Office of Research and Development
Idiopathic Pulmonary Fibrosis
Rehabilitation of Idiopathic Pulmonary Fibrosis (IPF) Patients
The incidence and prevalence of IPF increase exponentially with age, and IPF occurs more often in older males. Cigarette smoking and environmental dust exposures are known risk factors for developing IPF.
- Trial name
- NCT01118221
- Testing
- pulmonary rehabilitation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- US Department of Veterans Affairs
Heart Failure
Inorganic Nitrite to Amplify the Benefits and Tolerability of Exercise Training in Heart Failure With Preserved Ejection Fraction (HFpEF) (INABLE-Training)
Participants with heart failure with preserved ejection fraction will undergo 12 weeks of cardiac rehabilitation for exercise training (ET) and be randomized to either sodium nitrite or placebo through the training period.
- Trial name
- INABLE (NCT02713126)
- Testing
- Sodium Nitrite, Accelerometer, Cardiac Exercise Training
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Barry Borlaug
Cardiovascular Risk Factor, Cardiovascular Diseases
Effects of Breaking up Prolonged Sitting on Postprandial Cardiometabolic Disease Risk Markers in South Asian Adults
The purpose of this study is to examine whether breaking up prolonged sitting with short regular bouts of walking can reduce blood sugar and cholesterol levels after eating, which are risk markers for Type 2 diabetes and heart…
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Diabetes, Physical Activity
- Trial name
- NCT03898206
- Testing
- Breaking up sitting with walking breaks (INT-SIT), Prolonged sitting (SIT)
- Where
- United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Bedfordshire
Physical Activity
Milk Protein Feeding After Aerobic Exercise in Older Adults With Pre-diabetes Taking the Biguanide Metformin
The investigators propose that post-exercise milk protein feeding will enhance the mitochondrial protein synthesis (biogenesis) response to an exercise-training program.
- Trial name
- NCT02552355
- Testing
- Metformin, Carbohydrate Beverage, Protein Beverage
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Colorado State University
Hypoglycemia
Glucagon Ready-to-Use (RTU) for Prevention of Exercise-Induced Hypoglycemia During Aerobic Exercise in Adults With T1D
This study is a randomized, placebo-controlled, double-blind, 2-treatment, 2-period, crossover comparison in a clinical research center (CRC) setting, followed by a randomized, placebo-controlled, double-blinded, 2-arm parallel…
- Trial name
- NCT03841526
- Testing
- Glucagon RTU Injection With Insulin Pump Reduction, Vehicle for Glucagon RTU Injection With Insulin Pump Reduction, Glugaon RTU Injection Without Insulin Pump Reduction
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Xeris Pharmaceuticals
Childhood Obesity
Physical Activity and Screen-Time Regulations in Childcare Centers - Aim 2
Objective is to examine the physical activity and screen-time behaviors of children enrolled in licensed childcare centers before and after the enactment of new state regulations.
- Trial name
- Pause and Play (NCT02751814)
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
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