Clinical trials: Exercises
Low Back Pain
The Back Exercises to Neutralize Disability Study
A pilot randomized control trial (RCT) to generate effect sizes on the effects of blood flow restricted exercise on trunk extensor cross-sectional area (primary outcome), strength and endurance, whole body and regional lean mass…
- Trial name
- BEND (NCT02308189)
- Testing
- Exercise with blood flow restriction, Exercise
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Ohio University
Colon Cancer, Rectal Cancer
The Exercise And Colorectal Cancer Treatment Trial
This study will examine the biologic processes through which exercise may prevent disease recurrence in patients who have completed treatment for colorectal cancer.
- Trial name
- EXACT (NCT03975491)
- Testing
- Moderate-Intensity Aerobic Exercise, Wait-List Control
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Pennington Biomedical Research Center
Health and Wellbeing of Primary School-aged Children
Healthy Childcare Centre of the Future
Rationale: In 2015-2020, the Dutch 'Healthy Primary School of the Future' intervention took place. Two schools became 'Healthy Primary Schools of the Future'; providing a healthy lunch and structured physical activity (PA)…
- Trial name
- HCCF (NCT04193410)
- Testing
- Various health-promoting initiatives
- Where
- Netherlands
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Type 2 Diabetes Mellitus
Efficacy and Safety of Efpeglenatide Versus Placebo in Patients With Type 2 Diabetes Mellitus Inadequately Controlled With Diet and Exercise
Primary Objective: To demonstrate the superiority of once weekly injection of efpeglenatide in comparison to placebo in glycated hemoglobin (HbA1c) change in participants with T2DM (Type 2 Diabetes Mellitus) inadequately…
- Trial name
- AMPLITUDE-M (NCT03353350)
- Testing
- efpeglenatide (SAR439977)
- Where
- 54 sites in United States, Germany and 3 more
- Volunteers
- 406 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Type 2 Diabetes, High Blood Sugar
Evaluate Efficacy and Safety in Japanese Subjects With Type 2 Diabetes Mellitus
This is a 24-week randomised, multi-centre phase III study to evaluate the efficacy and safety of dapagliflozin as monotherapy in Japanese subjects with Type 2 diabetes mellitus who have inadequate glycemic control with diet and…
- Trial name
- NCT01294423
- Testing
- Dapagliflozin
- Where
- 26 sites in Japan
- Volunteers
- 261 people
- Sponsor
- AstraZeneca
Pediatric Obesity, Executive Function
Cognitive Aspects of Response to Treatment for Weight-related Health to Improve Eating and Exercise Earlier in Life
We plan to examine whether child and parental cognitive/executive function predict body composition outcomes and adherence to a 6-month protocol of Family-Based Behavioral Treatment (FBT), for pediatric obesity.
- Trial name
- CARTWHEEL (NCT03329300)
- Testing
- Family-based Behavioral Treatment (FBT)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Alabama at Birmingham
Frailty
Strength on Wheels: A Meal Delivery and Exercise Intervention for Homebound Older Adults
The purpose of this study is to implement a home-based exercise program, administered through Interfaith Ministries of Greater Houston Meals on Wheels (MOWGH), and evaluate its effects on frailty status and nutritional markers in…
- Trial name
- NCT04087343
- Testing
- Meals plus exercise, Meals only
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Health Science Center, Houston
Pulmonary Disease, Chronic Obstructive, Obesity
INtervention Study In overweiGHT Patients With COPD
Symptoms of chronic obstructive pulmonary disease (COPD) and high body mass index (BMI) overlap. The investigators are trying to find out if a program proven to help people lose a modest amount of weight and increase their…
- Conditions
- Pulmonary Disease, Chronic Obstructive, Obesity, Weight Loss, Life Style
- Trial name
- INSIGHT COPD (NCT02634268)
- Testing
- Lifestyle Intervention
- Where
- 39 sites in United States
- Volunteers
- 684 people
- Sponsor
- Seattle Institute for Biomedical and Clinical Research
Osteoarthritis
Weight Loss and Exercise for Communities With Arthritis in North Carolina
This study aims to develop and demonstrate the effectiveness of a systematic, practical, cost-effective diet-induced weight loss and exercise intervention in both urban and rural communities that can reduce pain and improve other…
- Trial name
- WE-CAN (NCT02577549)
- Testing
- Diet & Exercise, Attention Control
- Where
- 3 sites in United States
- Volunteers
- 823 people, healthy volunteers welcome
- Sponsor
- Wake Forest University
Low Back Pain
Physical Activity for Older Adults Chronic Low Back Pain
Chronic low back pain (cLBP) is one of the most common and disabling conditions among US military Veterans. Although physical activity can improve cLBP outcomes, the majority of Veterans with cLBP are inactive.
- Trial name
- PACe-LBP (NCT02327325)
- Testing
- Physical Activity, Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- VA Office of Research and Development
Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor, Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor
An Observational Study to Evaluate Physical Activity, Bleeding Incidence and Health Related Quality of Life, in Participants With Haemophilia A Without Inhibitors Receiving Standard of Care Treatment
This multicenter, non-interventional, prospective study will collect information about activity status, bleeds, health-related quality of life (HRQoL), health status, and safety in participants with moderate or severe haemophilia…
- Conditions
- Severe Hereditary Factor VIII Deficiency Disease Without Inhibitor, Moderate Hereditary Factor VIII Deficiency Disease Without Inhibitor, Haemophilia A
- Trial name
- POWER (NCT04165135)
- Testing
- Standard of Care for Haemophilia A
- Where
- 17 sites in Italy
- Volunteers
- 103 people
- Sponsor
- Hoffmann-La Roche
Cognitive Dysfunction, Breast Cancer Survivors
Physical Activity and Neuropsychological Outcomes in a Cancer Population
Many cancer survivors experience treatment-related impairments in mental abilities such as memory, attention, and concentration (known as cognition).
- Trial name
- NCT02332876
- Testing
- Exercise, Control
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of California, San Diego
Sleep, Physical Activity
Effects of a Wearable Device and Social Media-Based Intervention on Physical Activity and Sleep Quality in Adults
The goal of this randomized controlled trial is to examine whether the use of a wearable device and social media based intention increases physical activity and enhance sleep quality among adults.
- Trial name
- NCT06739876
- Testing
- Wearable device-based intervention (with motivational support via social media), Wearable device-based intervention (without support)
- Where
- Taiwan
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Chung Hsing University
Muscle Damage
Effect of Compression Garments on Exercise Performance Following Acute High Intensity Exercise
To examine the influence of compression garments manufactured with Far-Infrared technology on exercise performance during and after repeated eccentric isokinetic muscle actions of the leg extensors.
- Trial name
- NCT02076334
- Testing
- Far Infrared Fabric, Spandex
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Heart Failure
Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF)
This trial seeks to assess if potassium nitrate (KNO3) therapy improves exercise capacity and oxygen uptake in heart failure patients with preserved ejection fraction (HFpEF).
- Trial name
- NCT02840799
- Testing
- Potassium Nitrate (KNO3), Potassium Chloride (KCl)
- Where
- 3 sites in United States
- Volunteers
- 84 people
- Sponsor
- University of Pennsylvania
Fall
Impact of Telephone Coaching on Physical Performance in a Physical Exercise Maintenance Program for Fallers Elderly Patients Living at Home
At home, maintenance, physical performance declines more or less rapidly from 6 weeks depending advancing age and duration of the training period .
- Trial name
- STEP-PA (NCT02828826)
- Testing
- telephone coaching
- Where
- 10 sites in France
- Volunteers
- 101 people
- Sponsor
- Nantes University Hospital
Cancer Survivors, African Americans
Grateful Strides Toward Physical Activity and Well-Being for Black Breast Cancer Survivors
This pilot study will assess the feasibility of a gratitude intervention to promote physical activity, and well-being and positively impact biomarkers of health among older African American breast cancer survivors.
- Conditions
- Cancer Survivors, African Americans, Women, Psychology, Positive
- Trial name
- NCT05473026
- Testing
- Gratitude Intervention
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Florida
Non-metastatic, Hormone naïve Prostate Cancer
EXTEND Exercise Trial
This study will examine the effect of supervised exercise training on cardiopulmonary function in men receiving the combination of enzalutamide (ENZ) and androgen deprivation therapy (ADT) for treatment of non-metastatic…
- Trial name
- NCT02256111
- Testing
- Enzalutamide, Androgen deprivation therapy, Supervised exercise training
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Hypertension
Understanding the Exercise-Hypertension Paradox
Hypertension affects 37% of the Veteran population, making it the most common medical condition treated by the VA Health Care System. Physical activity is the first line of defense in the treatment and management of hypertension.
- Trial name
- NCT02034422
- Testing
- Oral Antioxidant, Exercise rehabilitation
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Depression, Physical Activity
Increasing Physical Activity Among Breast Cancer Survivors With Depression
Pilot study to assess a multi-component intervention to increase physical activity among breast cancer survivors with depression.
- Conditions
- Depression, Physical Activity, Breast Cancer
- Trial name
- NCT02781051
- Testing
- Print-based education, Fitbit, Active Living counseling
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Texas Southwestern Medical Center
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