Clinical trials: Exfoliation Glaucoma
Marfan's Syndrome With Ocular Manifestations, Pseudoexfoliation Syndrome
The Oscillation of Crystalline and Intraocular Lenses
The crystalline lens of the human eye helps to sharpen vision. There can be issues with the support/stability of the lens. This could be seen with the naked eye of an external observer or with the use of a slit lamp.
- Conditions
- Marfan's Syndrome With Ocular Manifestations, Pseudoexfoliation Syndrome, Cataract, Phakodonesis
- Trial name
- NCT04274634
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Anglia Ruskin University
Refractive Errors, Cataract
Refractive Outcomes After Cataract Surgery in Eyes With Pseudoexfoliation Syndrome
To evaluate the refractive outcomes of cataract surgery in PEX syndrome and determine which of the commonly used IOL formulas (SRK/T, Barrett Universal II and Hill-RBF) is the best in predicting postoperative refractive outcomes…
- Trial name
- NCT04783909
- Testing
- Phacoemulsification cataract surgery
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Lublin
Glaucoma, Open Angle Glaucoma
iCare® Home vs Goldmann Applanation Tonometry
Self-tonometry with iCare Home is regularly performed at Sankt Erik's Eye Hospital since a few years back. The purpose of this study was to show that the eye pressure measurements made with iCare® Home by patients / relatives do…
- Conditions
- Glaucoma, Open Angle Glaucoma, Ocular Hypertension, Pseudo Exfoliation Syndrome
- Trial name
- NCT04911387
- Testing
- Intraocular pressure measurments
- Where
- Sweden
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- St. Erik Eye Hospital
Pseudoexfoliation Syndrome, Cataract
Corneal Biomechanics and Surgically Induced Astigmatism in Pseudoexfoliation Syndrome
This prospective study aims to evaluate the influence of corneal biomechanical properties on surgically induced astigmatism following standard phacoemulsification cataract surgery in patients with pseudoexfoliation syndrome…
- Conditions
- Pseudoexfoliation Syndrome, Cataract, Astigmatism
- Trial name
- NCT07722247
- Testing
- phacoemulsification cataract surgery
- Where
- Croatia
- Volunteers
- 70 people
- Sponsor
- Kata Culina
Open Angle Glaucoma, Primary Open Angle Glaucoma
Safety and Effectiveness of the Hydrus Microstent
The purpose of this study is to assess the safety and effectiveness of the Hydrus Microstent for lowering intraocular pressure (IOP) in pseudophakic patients with open-angle glaucoma for whom IOP is not sufficiently controlled on…
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Glaucoma
- Trial name
- FRONTIER (NCT05198297)
- Testing
- Hydrus Microstent, Ophthalmic surgery
- Where
- 5 sites in United States
- Volunteers
- 33 people
- Sponsor
- Alcon Research
Glaucoma
Anterior Segment Imaging With Ultrahigh-resolution OCT in Patients With Glaucoma and PEX - a Pilot Study
The aim of the present study is to develop a measurement protocol for optimal imaging of the anterior segment of the eye, including anterior chamber angle, Schlemm's canal, filtering bleb and pseudoexfoliation deposits on the…
- Trial name
- NCT02865473
- Testing
- Pilocarpine
- Where
- Austria
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Pseudoexfoliation Syndrome in Cataract Myopic Eyes
Pseudoexfoliation Syndrome in Myopes
A retrospective study of 5753 eyes of cataract surgery patients was conducted at our Clinic. Ocular optical components measured by optical low coherence reflectometry biometer LENSTAR LS 900® of the cataract myopic eyes with…
- Trial name
- NCT01637740
- Volunteers
- 5,753 people
- Sponsor
- General Hospital Sveti Duh
Open Angle Glaucoma, Pigmentary Glaucoma
Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma
The Investigators will investigate the efficacy of combining the standalone iStent infinite and iDose that are minimally invasive surgical and drug depot options are a safe and effective alternative to filtering surgery for…
- Conditions
- Open Angle Glaucoma, Pigmentary Glaucoma, Pseudoexfoliation Glaucoma
- Trial name
- POAG (NCT07228221)
- Testing
- iStent infinite trabecular micro-bypass system model iS3, iDose TR (Travoprost intracameral Implant) 75mcg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Jonathon Myers
Open Angle Glaucoma, Primary Open Angle Glaucoma
IOP and Medication Reduction in MIGS Procedures
The primary objective of this research is to compare the efficacy of trabecular minimally invasive glaucoma surgery (MIGS) devices (iStent vs iStent Inject vs Hydrus) for intra ocular pressure (IOP) and anti-glaucoma medication…
- Conditions
- Open Angle Glaucoma, Primary Open Angle Glaucoma, Pigmentary Glaucoma, Pseudoexfoliation Glaucoma in Both Eyes
- Trial name
- NCT04202510
- Testing
- Glaucoma and Cataract Surgery
- Where
- United States
- Sponsor
- Wills Eye
Glaucoma, Glaucoma, Open-Angle
Impact of Self-tonometry on Glaucoma Treatment Decision.
Self-tonometry with iCare Home is performed by one hundred patients annually at Sankt Erik's Eye Hospital. The investigators want to evaluate the impact that self-tonometry results have on the clinician's choice of glaucoma…
- Conditions
- Glaucoma, Glaucoma, Open-Angle, OHT - Ocular Hypertension, Glaucoma Capsulare
- Trial name
- NCT04888156
- Testing
- Unchanged treatment, Changed treatment
- Where
- Sweden
- Volunteers
- 133 people
- Sponsor
- St. Erik Eye Hospital
Pseudoexfoliation Syndrome, Carpal Tunnel Syndrome (CTS)
Pseudoexfoliation and Carpal Tunnel Study
This prospective, single-center case-control study aimed to investigate the association between pseudoexfoliation syndrome (PES) and carpal tunnel syndrome (CTS) using biochemical markers.
- Trial name
- NCT06946030
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Glaucoma, Open-Angle, Pseudoexfoliation Glaucoma
Optimal Treatment Protocol for Selective Laser Trabeculoplasty
A randomized controlled trial to evaluate which treatment protocol in selective laser trabeculoplasty that is most optimal in terms of efficacy and safety.
- Conditions
- Glaucoma, Open-Angle, Pseudoexfoliation Glaucoma, Ocular Hypertension
- Trial name
- OSLT (NCT03798223)
- Testing
- SLT
- Where
- 4 sites in Sweden
- Volunteers
- 400 people
- Sponsor
- Vastra Gotaland Region
Glaucoma, Open-Angle, Glaucoma, Primary Open Angle
Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle Glaucoma
The purpose of this study is to follow and describe the outcomes of patients after selective and pascal laser trabeculoplasty treatment for chronic open-angle glaucoma.
- Conditions
- Glaucoma, Open-Angle, Glaucoma, Primary Open Angle, Exfoliation Glaucoma, Glaucoma, Pigmentary
- Trial name
- FPSPLTTCOAG (NCT02679482)
- Where
- Colombia
- Volunteers
- 36 people
- Sponsor
- Fundación Oftalmológica Nacional
Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma
XEN Glaucoma Gel Stent Versus Trabeculectomy
Multicentric evaluation of best corrected visual acuity of the XEN implant versus classic trabeculectomy in open angle glaucoma subjects
- Conditions
- Primary Open Angle Glaucoma, Pseudoexfoliation Glaucoma, Pigmentary Dispersion Glaucoma
- Trial name
- NCT05439161
- Testing
- surgery
- Where
- Austria
- Volunteers
- 196 people
- Sponsor
- Prof. Dr. Herbert Reitsamer
Lens Diseases
Association Between Pseudoexfoliation Syndrome and Diabetes Mellitus
Pseudoexfoliation syndrome (PEX) is characterized by the deposition of a distinctive fibrillar material in the anterior segment of the eye and was first described in 1917 by Lindberg.
- Trial name
- NCT03741153
- Testing
- slit lamp
- Volunteers
- 100 people
- Sponsor
- Assiut University
Cataract, Phacoemulsification
Intracameral Mydriasis Versus Topical Mydriasis in Cataract Surgery
The purpose is to determine if an intracameral solution of 0.2% tropicamide and 2% phenylephrine can dilate the pupil for cataract surgery as well as pre-operative topical 1% tropicamide and 5% phenylephrine.
- Conditions
- Cataract, Phacoemulsification, Mydriasis, Pseudoexfoliation Syndrome
- Trial name
- NCT00690222
- Testing
- Intracameral injection of mydriatic agent
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Nova Scotia Health Authority
Pseudoexfoliation Syndrome, Pseudoexfoliation Glaucoma in Both Eyes
Real World Evidence of Xen45 Gel Implant in Pseudoexfoliation Glaucoma
The Xen implant is an ab interno device that has been shown to be effective in reducing intraocular pressure in several types of glaucoma, although the evidence in pseudoexfoliative glaucoma is limited.
- Conditions
- Pseudoexfoliation Syndrome, Pseudoexfoliation Glaucoma in Both Eyes, Open Angle Glaucoma
- Trial name
- NCT06993311
- Testing
- Xen Gel Stent implantation
- Where
- Spain
- Volunteers
- 350 people
- Sponsor
- Xerencia de Xestión Integrada de Ferrol
Pseudoexfoliation Glaucoma, Primary Open-angle Glaucoma
Micropulse Laser Trabeculoplasty as Adjunctive Treatment in Patients With Pseudoexfoliation Glaucoma
This study aims to evaluate the effect of a single session of micropulse laser trabeculoplasty (MLT) on cornea in eyes with primary open glaucoma (POAG) and pseudoexfoliation glaucoma (PEXG).
- Trial name
- NCT03483402
- Testing
- Micropulse laser trabeculoplasty
- Volunteers
- 27 people
- Sponsor
- University Hospital of Patras
Glaucoma, Open-Angle, Suprachoroidal Space
Safety and Efficacy of Suprachoroidal Tube Shunt in Patients With Primary Open and Pseudoexfoliation Glaucomas
To assess safety and efficacy of a novel suprachoroidal silicone tube (SST) shunt for the treatment of primary open angle and exfoliative glaucomas.
- Conditions
- Glaucoma, Open-Angle, Suprachoroidal Space, Pseudo Exfoliation Syndrome
- Trial name
- NCT06154330
- Where
- Georgia
- Volunteers
- 91 people
- Sponsor
- Davinci LTD
Cataract, Diabetes
Aqueous Flare of a Hydrophobic Acrylic Single-piece Open-loop IOL With Modified Material Surface Properties
Modern phacoemulsification techniques have made cataract surgery safe and efficient over the past several decades. Although the phacoemulsification procedure has improved greatly, cataract surgery still involves trauma.
- Conditions
- Cataract, Diabetes, Pseudoexfoliation Syndrome
- Trial name
- POL (NCT01767012)
- Testing
- Polylens EC-HY10-PAL (coated), Polylens EC-Y10-PAL (uncoated)
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery