Clinical trials: Exhaustion Disorder
Exhaustion; Syndrome
Assessing the Impact of Acupuncture Therapy on Medical Resident Well-Being: Feasibility and Acceptance
This feasibility study develops methods for larger-scale research, evaluating the acceptability and perceived impact of a group acupuncture and acupressure intervention, as well as suitability of a self-report instrument.
- Trial name
- NCT03245034
- Testing
- Auricular Acupuncture Therapy
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Graft-Versus-Host Disease(GVHD), Anemia Due to Disturbance of Proliferation and/or Differentiation of Hematopoietic Stem Cells
CliniMACS® CD34+ Reagent System for Expanded Access Use
CliniMACs is an investigational device used to select and enrich stem cells. The device will select the stem cells with CD34+ protein.
- Conditions
- Graft-Versus-Host Disease(GVHD), Anemia Due to Disturbance of Proliferation and/or Differentiation of Hematopoietic Stem Cells, Graft Failure, Delayed Graft Function
- Trial name
- NCT02026934
- Testing
- CliniMACS CD34 Reagent System
- Where
- United States
- Sponsor
- Joseph Antin
Burnout, Professional, Exhaustion, Caregiver
Data-driven Approaches to Healthcare Provider Resilience & Burnout During COVID-19
The United States is battling dual pandemics: healthcare provider (HCP) exhaustion and COVID-19. The COVID-19 pandemic death toll has surpassed 595,000 and continues to climb as the worldwide outbreak continues.
- Conditions
- Burnout, Professional, Exhaustion, Caregiver, Covid19
- Trial name
- NCT04922632
- Testing
- Transcendental Meditation (TM), Experience Resolution Methodology (ERM), Transcendental Meditation (TM) and Experience Resolution Methodology (ERM)
- Where
- United States
- Volunteers
- 212 people
- Sponsor
- Duke University
Exhaustion; Syndrome
Effects of Acute Physical Activity in Patients With Exhaustion Disorder
A new stress-related diagnosis, Exhaustion disorder (ED), was introduced in the Swedish version of ICD-10 in 2005 and has since then increased rapidly.
- Trial name
- NCT06429423
- Testing
- Acute exercise low intensity, Acute exercise moderate intensity
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Victoria Blom
Heat Stroke, Heat Exhaustion
Chemical Ice Packs for Cooling Hyperthermic Patients
A common tool to cool people in the pre-hospital setting is the chemical ice pack. These are used by athletic trainers, EMS personnel, ER staff, and people in the prehosoital setting.
- Trial name
- NCT01694290
- Testing
- Chemical Cold Pack
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Stanford University
Burnout, Clinical Burnout
Comparing ACT, Recuperation, and ACT Plus Vocational Support for Clinical Burnout
This study compares three different online psychological treatments for people with clinical burnout (stress-related exhaustion) who are on sick leave or have major difficulties coping at work or in daily life.
- Conditions
- Burnout, Clinical Burnout, Exhaustion Disorder
- Trial name
- NCT07272421
- Testing
- ACT, Recuperation, Vocational support
- Where
- Sweden
- Volunteers
- 210 people
- Sponsor
- Uppsala University
Mental Health Issue, Cognitive Symptom
PrimeCog: Primary Care Cognitive Testing
The PrimeCog study aims to describe the symptomatology and pathophysiology of stress-induced exhaustion disorder (SED) and major depressive disorder (MDD) compared to healthy controls (HC).
- Conditions
- Mental Health Issue, Cognitive Symptom, Primary Health Care
- Trial name
- PrimeCog (NCT06346535)
- Testing
- Cognitive Testing
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Region Östergötland
Burnout, COVID-19
Randomized Controlled Trial of the Mindful Compassion Care Program in Reducing Psychological Distress Amongst Nurses During the COVID-19 Pandemic
Recent studies have shown that nurses have been more affected by the COVID-19 pandemic than any other group of hospital workers in terms of anxiety, depression, and burnout.
- Trial name
- MCCP-COVID19 (NCT05308537)
- Testing
- Mindful Compassion Care Program
- Where
- Italy
- Volunteers
- 33 people
- Sponsor
- Universita di Verona
Myeloma Multiple
Immune Fitness in Older Patients With Relapsed and Refractory Multiple Myeloma
Relapsed/refractory multiple myeloma (RRMM) predominantly affects older adults, who exhibit marked heterogeneity in treatment outcomes despite receiving the same therapies.
- Trial name
- PRIME (NCT07674498)
- Testing
- immunophenotyping of lymphocyte
- Where
- 3 sites in Belgium
- Volunteers
- 31 people
- Sponsor
- Jules Bordet Institute
Cardiovascular Diseases Risk
Circulating Vascular Regenerative Cell Exhaustion in Individuals Without Type 2 Diabetes Who Are of South Asian or European Origins
ORIGINS-VRCE-2 is an observational study aimed to assess how blood vessel forming stem cells from individuals without diabetes or a history of cardiovascular disease differ between individuals of South Asian and European…
- Trial name
- ORIGINS-VRCE-2 (NCT06769347)
- Where
- 5 sites in Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Canadian Medical and Surgical Knowledge Translation Research Group
Exhaustion; Syndrome, Burnout Syndrome
Rehabilitation for Improved Cognition
Many patients with exhaustion disorders continue to have significant difficulties with attention and memory function which reduce their work ability.
- Trial name
- RECO (NCT03073772)
- Testing
- Computer-based cognitive training, Physical fitness training
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Umeå University
Burnout, Professional
Decision Fatigue and Emotional Exhaustion Among Anesthesiologists
This study aims to evaluate the level of decision fatigue among anesthesiologists actively practicing in clinical settings in Turkey and to examine its relationship with emotional exhaustion.
- Trial name
- NCT07089160
- Testing
- Online Survey (Decision Fatigue Scale and Emotional Exhaustion Scale)
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Istinye University
Exhaustion Disorder, Stress-Related Disorders
Step by Step Back - A Feasibility Study of a Physical Activity Intervention for Adults With Stress-related Exhaustion
The goal of this clinical study is to learn whether a psychologist- or psychotherapist-guided physical activity program can be delivered and used as part of regular care for adults experiencing stress-related exhaustion.
- Trial name
- NCT07407829
- Testing
- CBT/ACT-based psychologist-delivered physical activity program
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- The Swedish School of Sport and Health Sciences
Horticultural Therapy, Anxiety
The Effect of Horticultural Therapy on Mental Health and Burnout Levels of Nursing Home Workers
The incidence of people with disabilities in need of care services is increasing all over the world. This situation significantly increases the need for nursing homes and caregivers.
- Conditions
- Horticultural Therapy, Anxiety, Depression, Stress
- Trial name
- NCT06484959
- Testing
- Assigned Interventions
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Elective Abdominal Aortic Aneurysm
Elective Abdominal Aortic Aneurism - Open Versus Endovascular Repair
Abdominal aortic aneurysm (AAA) is a life threatening disease. There is a consensus to propose surgical repair in patients with a reasonable operative risk when the AAA exceeds 5 cm in diameter.
- Trial name
- ACE (NCT00224718)
- Testing
- Endovascular repair (with endograft), Open repair
- Where
- France
- Volunteers
- 306 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Melanoma
Pembrolizumab Effects on NK Cell Exhaustion in Melanoma (Merck NK-IIT)
Melanoma is an immune-modulated malignancy and immune checkpoint modulators which inhibit PD-1 function (pembrolizumab, nivolumab) have demonstrated clinical efficacy as treatment for patients with stage IV melanoma.
- Trial name
- NCT03241927
- Testing
- Pembrolizumab
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Nina Bhardwaj
Immune System Diseases, COVID-19 Vaccine Adverse Reaction
COVID-19 Post-Vaccination Observation
The study started after the second COVID-19 vaccination of the participant with blood spots appearing on the skin with severe arthritis.
- Conditions
- Immune System Diseases, COVID-19 Vaccine Adverse Reaction, Immune System Disorder
- Trial name
- NCT06107348
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis, PhD
Metastatic Breast Cancer, Bevacizumab-alone Maintenance Treatment Progression
Abrogation of Chronic Monoclonal Antibody Treatment-induced T-cell Exhaustion With DURVALUMAB in Advanced HER-2 Negative Breast Cancer
This is a single-arm pilot proof of concept, open-label clinical trial. Twenty-five subjects will be enrolled in 6 sites. Metastatic breast cancer patients with disease progression to bevacizumab maintenance treatment will be…
- Trial name
- NCT02802098
- Testing
- Durvalumab, Bevacizumab
- Where
- 6 sites in Spain
- Volunteers
- 25 people
- Sponsor
- Centro Nacional de Investigaciones Oncologicas CARLOS III
Mental Fatigue, Near Infrared Spectroscopy
The Effect of Mental Fatigue on the Cerebral Oxygenation During Endurance Exercise
The experiment will consist of 3 consecutive trials performed in a sound-insulated climate chamber (20°C and 40% RH) at the VUB. Participants will be asked to return 3 successive weeks.
- Conditions
- Mental Fatigue, Near Infrared Spectroscopy, NIRS, Condition
- Trial name
- NCT05355493
- Testing
- Time to Exhaustion cycling test, Go/NoGo task
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Heart Rate Variability, Burnout
Helping Overcome Pressure and Exhaustion: Empowerment Classes for Southeast Asian Migrant Care Workers
As Taiwan's population ages, Southeast Asian migrant care workers are widely employed to fill the care labor gap. These workers often face symptoms of burnout and emotional stress due to long working hours and high-pressure…
- Conditions
- Heart Rate Variability, Burnout, Depression
- Trial name
- HOPE (NCT06532305)
- Testing
- HOPE empowerment classes
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital