Clinical trials: Expectations, open to volunteers
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT): Sense of Control and Symptom Expectations as Targets of a Treatment for PNES
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- NCT05096273
- Testing
- ReACT
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Erythema Migrans
Patient's Pretreatment Expectations About Post-Lyme Symptoms
The investigators will focus on pretreatment expectations of patients with early Lyme disease manifested as erythema migrans with the aim of assessing the association between pretreatment expectations quantified with a…
- Trial name
- NCT03462329
- Testing
- Antibiotics (preferentially oral doxycycline 100 mg bid)
- Where
- Slovenia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Adults
Turkish Validity-Reliability of the Outcome Expectations For Yoga Scale
Evaluation of the Turkish validity and reliability of the outcome Expectations for Yoga (OEY) Scale, which was developed to evaluate attitudes and beliefs related to yoga practice
- Trial name
- NCT06568341
- Testing
- validity and reability study
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Healthy
Neurofeedback to Reduce Spontaneous Recovery of Threat Expectancy
This study tests the efficacy of a new behavioral intervention with the goal of reducing spontaneous recovery of threat expectancy in healthy adults.
- Trial name
- NCT07122739
- Testing
- Active Real-time fMRI Neurofeedback
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Trustees of Princeton University
PARKINSON DISEASE (Disorder)
The Role of Priors in Hallucinatory Perception in Parkinson's Disease
The goal of this observational study is to better understand the mechanisms of hallucinations in patients with Parkinson's disease.
- Trial name
- LEAP-PARK (NCT07427498)
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Convulsion, Non-Epileptic
Retraining and Control Therapy (ReACT) R33 Phase
The purpose of this study is to assess sense of control and catastrophic symptom expectations as targets for Retraining and Control Therapy (ReACT- an intervention focused on changing behaviors and thoughts) for treatment of…
- Trial name
- ReACT (NCT06007053)
- Testing
- ReACT, Supportive Therapy
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Aging, Mortality
Longevity Metrics AI/ML Development Study
This study builds AI models that score diagnostic screening tests, and that predict screening results, clinical judgment, and life expectancy.
- Conditions
- Aging, Mortality, Cardiovascular Disease Prevention, Metabolic Syndrome
- Trial name
- NCT07808619
- Testing
- AIML scored health screening battery
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Self-perceptions of Aging, Physical Activity
Reframing Expectations About Aging - Physical Activity and Inclusive Reappraisal
The goal of this clinical trial is to promote positive views on aging and walking in Spanish partners aged 65 years and over. The trial will comprise three arms.
- Trial name
- RE-PAIR (NCT07113860)
- Testing
- Views on Aging Intervention, Projecte Moviment
- Where
- Spain
- Volunteers
- 342 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
Breastfeeding Expectations, Breastfeeding Avoidance
The Effect of a Virtual Reality Breastfeeding Experience on Breastfeeding Expectations and Avoidance
This randomized controlled trial aims to examine the effect of a virtual reality breastfeeding experience on breastfeeding expectations during pregnancy and breastfeeding avoidance after childbirth.
- Trial name
- NCT07901010
- Testing
- Simulation of Virtual Reality
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ebru Ertas
Hypertension, Elevated Blood Pressure
Blood Pressure Following Isometric Exercise in Inactive Adults
This study investigates how isometric exercise training (IET) affects blood pressure in physically inactive adults. Isometric exercise involves sustained muscle contractions without movement-for example, pushing against a fixed…
- Conditions
- Hypertension, Elevated Blood Pressure, Sedentary Lifestlye
- Trial name
- BELIEF-BP (NCT06937164)
- Testing
- Isometric Exercise Training (IET), Expectation-Enhancing Informational Framing
- Where
- United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Canterbury Christ Church University
Health Behavior, Quality of Life
The Lake Nona Life Project
The Lake Nona Life Project aims to examine the health and wellness of participants over the course of multiple years, focusing on the links between health and wellness, longevity, quality of life, and human performance.
- Conditions
- Health Behavior, Quality of Life, Aging
- Trial name
- NCT02533804
- Where
- United States
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Aging, Aging Well
100-Year Human Aging Study
The 100-Year Human Aging Study is a prospective, pragmatic, observational trial enrolling participants across fixed clinical sites, mobile clinical sites, and an online participation pathway (current and future) to undergo…
- Conditions
- Aging, Aging Well, All-Cause Mortality, Mortality
- Trial name
- NCT07563777
- Testing
- Comprehensive Multi-System Clinical Screening
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Aging, Mortality
Human Observatory Study
The Human Observatory Study is a prospective observational and ecological surveillance study building a continuously-updating world model for human health, disease, and death at the individual and population level.
- Conditions
- Aging, Mortality, All-cause Mortality, Life Expectancy
- Trial name
- HOS (NCT07646782)
- Testing
- Multi-Domain Ecological and Clinical Data Linkage
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Longevity Metrics, Inc.
Health Services Accessibility, Rural Health
Health Ahead Comparative Effectiveness Study
The Health Ahead Comparative Effectiveness Study is a pragmatic, parallel-arm interventional platform that systematically compares successive changes to preventive health screening on the path toward a fully automated screening…
- Conditions
- Health Services Accessibility, Rural Health, Medically Underserved Area, Preventive Health Services
- Trial name
- HACE (NCT07669168)
- Testing
- AI-Assisted Screening Interpretation (AI Reads), Human-Only Screening Interpretation
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- William Brandenburg, MD
Positive Expectations
Positive Expectation Effects on Early Emotional Processing
Insights into the mechanisms of expectation effects in the emotional domain can be invaluable for the development of potential therapeutic interventions for mood disorders.
- Trial name
- NCT07615530
- Testing
- Saline Nasal Spray
- Where
- Germany
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Physical Performance, Placebo Effect
Placebo Effect on Cycling Performance: Laboratory Crossover Study
This study aims to determine the impact of the placebo (PLA) effect on physical and cognitive performance in a controlled laboratory setting.
- Conditions
- Physical Performance, Placebo Effect, Cognitive Performance
- Trial name
- NCT07748429
- Testing
- Caffeine (6mg/kg)
- Where
- Poland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Physical Performance, Placebo Effect
Placebo Effect in Field-Based Physical Performance
This study aims to investigate the placebo (PLA) effect on physical performance across different sports disciplines in real-world, field-based settings.
- Conditions
- Physical Performance, Placebo Effect, Cognitive Performance
- Trial name
- NCT07742150
- Testing
- Caffeine (6mg/kg)
- Where
- Poland
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Lower Limb Amputation
Study of Locomotor Expectations for Ascending/Descending Slope and Stairs in Patients With Limb Amputations
Patients with lower limb amputations are equipped with prostheses that can be mechanical and/or electronic. These prostheses can be mono-articular (only the ankle) or bi-articular (knee and ankle for example).
- Trial name
- JCE (NCT04030650)
- Testing
- Functional analyses, 3D analysis of walking and balance
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Negative Affectivity, Non-invasive Brain Stimulation
Neural Mechanisms of Interpersonal Expectations on Negative Affect
The goal of this clinical trial is to learn whether non-invasive brain stimulation, called transcranial temporal interference stimulation (tTIS), can reduce negative affect, and how expectations shaped by care providers influence…
- Conditions
- Negative Affectivity, Non-invasive Brain Stimulation, Placebo Effect, Expectations
- Trial name
- NCT06980090
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Healthy Volunteers
Showers and Stress
The study investigates whether repeated exposure to cold showers can improve the ability to cope with and respond to stress. In particular, it examines both the psychophysiological effects of cold showers and the role of…
- Trial name
- S A S (NCT07611422)
- Testing
- Positive expectation about the effects of cold and warm showers, No expectation regarding the exposure to cold water and/or to warm showers
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart