Clinical trials: Expectations
Attentional Bias, Smoking Cues
Trial on the Effect of E-cigarette Advertising on Cigarette Perceptions in Adolescents
This research aims to investigate how exposure to advertising for Electronic Nicotine Delivery Systems (commonly called e-cigarettes) may lead to combustible smoking initiation in adolescents.
- Conditions
- Attentional Bias, Smoking Cues, Positive Perceptions About Cigarette Smoking, Social Norms
- Trial name
- NCT03786042
- Testing
- E-cigarette ad exposure, non e-cigarette TV commercials
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Trustees of Dartmouth College
Episodic Migraine
The Effects of Expectation and Knowledge on Rizatriptan and Placebo Treatment of Acute Migraine Headache
Evidence-based medicine depends on distinguishing between pharmacological effects and placebo effects in randomized controlled trials (RCT).
- Trial name
- NCT00719134
- Testing
- Maxalt
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Beth Israel Deaconess Medical Center
Gratitude + No Expectations, Gratitude + Expectations
The Effects of Manipulating Expectations in a Gratitude Intervention
Gratitude - an emotion felt when an individual receives something beneficial from other people or entities - has been shown to positively affect well-being.
- Conditions
- Gratitude + No Expectations, Gratitude + Expectations, Events Control
- Trial name
- NCT03784001
- Testing
- Gratitude + No Expectations Intervention, Gratitude + Expectations Intervention, Events Control Intervention
- Where
- United States
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Alcohol; Use, Problem
Alcohol & Mobile Phone Study to Reduce High-risk Alcohol Use and Consequences
The proposed study will develop a smartphone/mobile app intervention that incorporates ecological momentary assessment (i.e., two brief surveys per day) and daily intervention messaging (2 messages per day) for three weeks to…
- Trial name
- AMPS (NCT04213846)
- Testing
- Experimental: Mobile Alcohol Expectancy Intervention
- Where
- United States
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- University of Washington
Osteoarthritis
Pain Expectations in Subjects With Osteoarthritis
The purpose of this research study is to test whether or not researchers can alter or change expectations on pain. The researchers will test whether there is an effect on the size of the pupil and responses to thermal heat…
- Trial name
- NCT02155257
- Testing
- Modafinil, Gabapentin
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Stress-related Problems
Effects of Stress-reducing Aromatherapy
The study purpose is to evaluate efficacy of stress-reducing aromatherapy and learn about how aromatherapy works.
- Trial name
- NCT01307748
- Testing
- aroma
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Caries, Dental, Health Behavior
Interactive Parent-Targeted Text Messaging in Pediatric Clinics to Reduce Caries Among Urban Children
This is a randomized clinical trial to test the efficacy of a parent-targeted text message-based intervention program on caries incidence and oral health behaviors (child and parent).
- Trial name
- iSmile (NCT03294590)
- Testing
- OHT Parent targeted text messages, CWT Parent targeted text messages
- Where
- United States
- Volunteers
- 754 people, healthy volunteers welcome
- Sponsor
- Boston University
Healthy
N-of-few Study of Pain Perception
A behavioral study that will examine how pain perception is affected by different types of conditioning and by context, with a few participants and multiple sessions ("N-of-few" design).
- Trial name
- NOF (NCT04664400)
- Testing
- Symbolic conditioning, Conditioning, Instructions
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Medication Adherence
Balanced Placebo Design With Varenicline: Pharmacological and Expectancy Effects on Medication Adherence
The current study will use the double-blind balanced placebo design to examine differences between expectancies versus the pharmacological effects of varenicline medication administered for two weeks to cigarette smokers.
- Trial name
- NCT03538808
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Trauma, Opioid Use
Relieving Acute Pain (RAP) Study: A Pilot Study
The United States (US) faces a crisis of pain management. According to the 2012 National Health Interview Survey, almost 50 million adults in the US reported having significant chronic or severe pain (Nahin 2015).
- Conditions
- Trauma, Opioid Use, Spine Fusion
- Trial name
- NCT03426137
- Testing
- Oxycodone, Ketorolac
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Maryland, Baltimore
Anxiety Disorders
Expectation of Unpleasant Events in Anxiety Disorders
Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate.
- Trial name
- NCT00055224
- Testing
- Threat of shock
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Lumbar Spine Surgeries, Cervical Spine Surgeries
Impact of Surgical Theater's Patient Engagement
To evaluate usefulness of Surgical Theater's Patient Engagement 360VR platform in helping align patient expectations and improve patient satisfaction and understanding in spinal surgery consults.
- Trial name
- ISTPE (NCT05334212)
- Testing
- Surgical Theater
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- University Hospitals Cleveland Medical Center
Nausea
Alternative Approaches for Nausea Control
216 Chemotherapy-naïve, female breast cancer patients about to begin chemotherapy and who expect to have nausea, will be entered.
- Trial name
- NCT01695993
- Testing
- Acupressure bands, Expectancy-neutral handout, Expectancy-neutral MP3
- Where
- 4 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Rochester
Decision Making About Life-sustaining Treatment in Patients With Serious Cardiac, Respiratory and Oncological Conditions Likely to Limit Life Expectancy
Intuition vs. Deliberation in Medical Decision Making
The purpose of this study is to determine whether there are systematic differences between the decisions patients make intuitively versus deliberatively about life-sustaining medical therapies.
- Trial name
- NCT02487810
- Testing
- Cognitive load, Deliberative instructions
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pennsylvania
Pain
The Neurobiology of Expectancy and Pain Perception
This study will use using fMRI (functional Magnetic Resonance Imaging) to elucidate how contextual learning/expectation relieves or aggravates pain experience in the same cohort of subjects and the same study session.
- Trial name
- NCT01575106
- Testing
- Heat pain applied using TSA or CHEPS
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
HIV/AIDS, Chronic HIV Infection
Life Plans Intervention Study
The mass provision of HIV treatment in rural KwaZulu-Natal, South Africa has raised adult life expectancy by 18 years since 2003.
- Conditions
- HIV/AIDS, Chronic HIV Infection, Health Knowledge, Attitudes, Practice
- Trial name
- NCT03215901
- Testing
- A Beautiful Future Video, Active Control Video
- Where
- South Africa
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Boston University
Abuses Over-The-Counter/Prescription Medications, Pain, Postoperative
Expectations and Pain Control Advancement In surgeRy: The REPAIR Trial
This is a randomized control trial that aims to evaluate whether patient-centered education, compared to routine education, decreases narcotic consumption without interfering with return to physical activity following hospital…
- Conditions
- Abuses Over-The-Counter/Prescription Medications, Pain, Postoperative, Opioid Use, Physical Activity
- Trial name
- REPAIR (NCT03726476)
- Testing
- Patient centered pre-op education, routine preop education
- Where
- 2 sites in United States
- Volunteers
- 174 people
- Sponsor
- University of New Mexico
Placebo, Expectations
Effects of Expectations on Negative Affect, Perceived Cognitive Effort, and Pain
The investigators administer a functional neuroimaging task to investigate the effect of cue expectancy on participants' self-reported ratings across a variety of affective and cognitive domains.
- Trial name
- NCT05425563
- Testing
- Pain Expectancy Cues, Vicarious Pain Expectancy Cues, Cognitive Effort Expectancy Cues
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Perception Disturbance, Visual Suppression
Visual Surround Suppression and Perceptual Expectation Under Psilocybin
The prospective pilot study will address the critical need for more precise characterizations of the acute visual effects of the drug psilocybin by measuring the impact of acute psilocybin intoxication on a perceptual task known…
- Conditions
- Perception Disturbance, Visual Suppression, Psychedelic Experiences
- Trial name
- NCT04424225
- Testing
- Psilocybin, Niacin
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Pancreatic Cancer, Ductal Adrenocarcinoma
Study of Safety and Tolerability of PCI-27483 in Patients With Pancreatic Cancer Patients Receiving Treatment With Gemcitabine
The purpose of this study is to evaluate the safety and tolerability of selected dose 1.2mg/kg BID dosage administered subcutaneously (SC) administered PCI-27483 to metastatic or locally advanced pancreatic cancer patients…
- Conditions
- Pancreatic Cancer, Ductal Adrenocarcinoma, Exocrine Pancreatic Cancer
- Trial name
- NCT01020006
- Testing
- PCI-27483, Gemcitabine
- Where
- 17 sites in United States
- Volunteers
- 42 people
- Sponsor
- Pharmacyclics LLC.