Clinical trials: Exposure, Environmental
Acute Aortic Syndrome
The EnvScore-Aorte Diagnostic Study Protocol for the Identification of Acute Aortic Syndrome
The goal of this retrospective observational study is to evaluate the diagnostic performance of the AORTAs score integrated with environmental exposure data (AORTAs-E) for the identification of Acute Aortic Syndrome (AAS) during…
- Trial name
- EnvScore Aorte (NCT07467486)
- Volunteers
- 580 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Environmental Exposure, Physical Activity
Neurophysiological Mechanisms of Physical Activity Interventions in Unique Environments
This randomized intervention is designed to compare the influence of physical activity in natural and urban environments on cognitive and physical health.
- Trial name
- NCT03501953
- Testing
- Physical Activity
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northeastern University
Allergic Conjunctivitis
Assessing the Efficacy of Maxidex® and Patanol® for the Treatment of Allergic Conjunctivitis
The purpose of this study was to evaluate the efficacy of Maxidex and Patanol compared to placebo in patients with allergic conjunctivitis when exposed to controlled allergen levels in an Environmental Exposure Chamber (EEC).
- Trial name
- NCT01119287
- Testing
- Dexamethasone 0.1% ophthalmic suspension, Olopatadine hydrochloride 0.1% ophthalmic solution
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Alcon Research
Effect of Game in Increasing Environmental Health Literacy
Evaluation of Prototype for Simulation for Environmental Exposure Education (SE3)
The goal of this clinical trial is to test a prototype of a new educational game about environmental health literacy with middle school age youth.
- Trial name
- SE3 (NCT05875467)
- Testing
- SE3 Game
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- dfusion Inc
Healthy Adult Participants
Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure
The goal of this observational study is to evaluate the feasibility and usability of at-home urine sample collection, preparation, and smartphone imaging using the EcoExposure™ platform in adults.
- Trial name
- OMNU (NCT07775495)
- Where
- 51 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Ecotera Health LLC
Infant Environmental Tobacco Smoke Exposure
Reducing Environmental Tobacco Smoke in Neonatal Intensive Care Unit (NICU) Infants' Homes
This study is about reducing the risks of smoke-related infant health problems. Research has shown that infants exposed to secondary smoke have higher risks of delayed lung development, respiratory illnesses, wheeze, cough…
- Trial name
- NCT00670280
- Testing
- Motivational Interviewing intervention, Usual Care, Usual Care - Reduced Measurement
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- The University of Texas Health Science Center, Houston
Environmental Exposures, Child Development
HOME Study (Health Outcomes and Measures of the Environment Study)
The goal of the HOME Study is to quantify the impact of low-level fetal and early childhood exposures to environmental toxicants including lead, mercury, and other metals, pesticides, polychlorinated biphenyls (PCBs), persistent…
- Conditions
- Environmental Exposures, Child Development, Lead and Injury Reduction
- Trial name
- NCT00129324
- Testing
- Lead Hazard Control Intervention, Injury Hazard Control Intervention
- Where
- United States
- Volunteers
- 468 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Allergic Contact Dermatitis, Metal Allergy
Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases
The goal of this clinical trial is to collect environmental, bio-humoral, and clinical data derived from patients with allergic contact dermatitis (ACD) and systemic metal allergic syndromes related to the exposure to heavy…
- Conditions
- Allergic Contact Dermatitis, Metal Allergy, Food Allergy, Nickel Sensitivity
- Trial name
- MATRIOSKA (NCT06529913)
- Testing
- Collection of environmental, biological, and clinical data
- Where
- 2 sites in Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Seasonal Allergic Rhinitis
Effect of Loratadine/Montelukast Combination on Congestion in SAR Patients Exposed to Pollen in an EEU (Study P04822)
This is study of LMC, phenylephrine, and placebo in subjects with SAR. There are three visits: At Visit 1, subjects will be evaluated for participation and, if they qualify, will attend Visit 2 for priming.
- Trial name
- NCT00423995
- Testing
- Loratadine/montelukast combination
- Volunteers
- 379 people
- Sponsor
- Organon and Co
Risk Reduction, Environmental Exposure
Monitoring Environmental Exposures and Behavioral Change
The goal of this study is to examine what effect real-time feedback on particulate matter (PM) air pollution levels has on risk recognition and behavior.
- Conditions
- Risk Reduction, Environmental Exposure, Risk Behavior, Health
- Trial name
- NCT05338242
- Testing
- Real-Time Exposure Feedback
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Stroke
Comparison of Training in Virtual Environment With and Without Physiotherapeutic Intervention in Chronic Stroke Patients
The aim of this study is to compare the effects of balance training in a virtual environment with and without physiotherapeutic intervention on the motor function, balance and gait in chronic stroke patients.
- Trial name
- NCT03361241
- Testing
- No Physiotherapeutic Intervention, Physiotherapeutic Intervention
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo General Hospital
Allergic Asthma, Allergic Rhinitis
Efficacy of Face Mask in Reducing Respiratory Allergic Symptoms in Birch-allergic Subjects in ALYATEC Exposure Chamber
There is no clinical evidence that face masks are efficient in birch pollen-induced asthma. As the use of face masks has become widespread worldwide to limit the spread of SARS-CoV-2, this study aims to demonstrate the clinical…
- Trial name
- NCT06267261
- Testing
- KOLMI® surgical face mask (OP-Air)
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Alyatec
Pollution; Exposure, Environmental Exposure
The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing
To quantify health effects of synergizing chemical and biological pollutants in a targeted population setting, i.e., school-aged children. Indoor air pollutants will be monitored within the classrooms with high end sensors.
- Conditions
- Pollution; Exposure, Environmental Exposure, Childhood Asthma, Childhood
- Trial name
- SynAir-Child (NCT05105386)
- Testing
- SynAir-Child
- Volunteers
- 3,000 people
- Sponsor
- National and Kapodistrian University of Athens
Environment, Pollution Exposure
Environmental Pollutants and Life Quality
This study is part of the MISTRAL project, funded by the European Commission under the Horizon Europe Program, within the Work Programme 2021-2022 of Pillar II - Health Cluster on Environment and Health, which has the main…
- Conditions
- Environment, Pollution Exposure, Mortality, Healthcare
- Trial name
- ZEPHYR (NCT06591988)
- Testing
- Lifestyle factors
- Where
- Italy
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- Azienda Sanitaria Locale di Taranto
Rhinitis, Allergic, Perennial, Rhinitis, Allergic, Nonseasonal
A Dose-Ranging Study of the Safety and Effectiveness of MK-8237 in the Treatment of House Dust Mite (HDM) Induced Allergic Rhinitis/Rhinoconjunctivitis in Adults (MK-8237-003/P07627)
The purpose of this study is to evaluate the dose-related effectiveness, the safety and the tolerability of MK-8237, compared to placebo, in the treatment of house dust mite (HDM)-induced allergic rhinitis/rhinoconjunctivitis in…
- Trial name
- NCT01644617
- Testing
- MK-8237 6 DU, MK-8237 12 DU
- Volunteers
- 124 people
- Sponsor
- ALK-Abelló A/S
Hospital Acquired Infection, Ventilator-associated Pneumonia
Study on Dynamic Environmental Exposome of ICU and the Establishment of Microbial Transmission Model Between Environment and Host
HAI (Hospital-acquired infection) is very common in ICU，and lack of understanding of environmental exposure omics and environment-host microbial interactions restricts the prevention and control of HAI.
- Trial name
- NCT05877625
- Testing
- Expectoration care
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Peking University Third Hospital
Hypoxia, Altitude, Cold Exposure
Effects of Physical Training in Altered Environmental Conditions on Exercise Performance
The main objective of the study is to evaluate the physiological-biochemical effects of physical training under artificially altered climatic conditions (using a hypoxic thermoclimatic chamber) in particular to determine the…
- Conditions
- Hypoxia, Altitude, Cold Exposure, Heat Exposure
- Trial name
- NCT06159374
- Testing
- exercise and environmental conditions
- Where
- Poland
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University School of Physical Education, Krakow, Poland
Inflammation, Normal Controls
Natural History of the Human Biological Response to Environmental Exposure and Injury
Background: Environmental exposures like pollution, diet, and stress can help cause human diseases, or make them worse. Researchers want to better understand how injury and inflammation are caused by these exposures.
- Conditions
- Inflammation, Normal Controls, Metabolic Disease
- Trial name
- NCT04888923
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Cat Allergy, Rhinoconjunctivitis
Cat-PAD Follow on Study
Cat allergy is an increasingly prevalent condition, affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma.
- Trial name
- NCT01272323
- Testing
- Cat-PAD Dose 1, Cat-PAD Dose 2
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- Circassia Limited