Clinical trials: Exposure Occupational
Noise Exposure, Hearing Loss, Noise-Induced
A Multilevel Intervention to Prevent Noise Exposure in Farmworkers
This study will test a program to reduce noise exposure and prevent hearing loss among farmworkers. Farmworkers are often exposed to high levels of noise from machinery, which can lead to hearing loss over time.
- Conditions
- Noise Exposure, Hearing Loss, Noise-Induced, Occupational Exposure
- Trial name
- POP (NCT07554378)
- Testing
- Multilevel Hearing Protection Training
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Musculoskeletal Disorder, Anxiety Disorders
A Multicentre Randomised Controlled Trial of the Norwegian Health in Work Service. The NSAC Efficacy Study
The Norwegian Sickness Absence Clinic (NSAC) is a publicly funded specialist outpatient health service, which is uniquely available for the work force.
- Conditions
- Musculoskeletal Disorder, Anxiety Disorders, Depression, Fatigue
- Trial name
- NSAC (NCT05310695)
- Testing
- NSAC - rapid, NSAC - ordinary, NSAC - active control
- Where
- 5 sites in Norway
- Volunteers
- 2,500 people
- Sponsor
- Nordlandssykehuset HF
Hiv
Evaluation of (Doravirine / Lamivudine / Tenofovir Disoproxil Fumarate) (Delstrigo®) as a New Strategy for Non-occupational Post Exposure Prophylaxis, a Prospective Open Label Study
Subjects who go to emergency room for possible contact to HIV transmission receive Delstrigo as post exposition prophylaxis.
- Trial name
- DORAVIPEP (NCT04233372)
- Testing
- Delstrigo
- Where
- 2 sites in France, Spain
- Volunteers
- 399 people
- Sponsor
- Hospital Clinic of Barcelona
Lung Cancer Screening, Asbestos
Artificial Intelligence in Lung Cancer Screening
Single-center, non-profit, observational, retrospective study of collection of clinical and amnestic data and images to create, implement and develop a pilot model of an integrated virtual platform.
- Trial name
- INAIL BRIC (NCT06444373)
- Where
- Italy
- Volunteers
- 728 people, healthy volunteers welcome
- Sponsor
- Scientific Institute San Raffaele
Lung Cancer
Development of a Biologic Specimen Bank for the Study of Early Markers of Lung Cancer Among Tin Miners in Yunnan, China
The overall goal of this project is to identify strategies to reduce lung cancer incidence and mortality. Using a high-risk occupational cohort, our specific objectives are 1) to establish a biologic specimen bank and data bank…
- Trial name
- NCT00340405
- Where
- China
- Volunteers
- 9,759 people
- Sponsor
- National Cancer Institute (NCI)
Domestic Violence, Intimate Partner Violence
The Relationship of Occupational Competence and Activity Role Participation to Life Satisfaction and Depression Severity in Women Exposed to Domestic Physical Violence at a Social Service Institution
The goal of this observational study is to examine the relationships between occupational competence, activity and role participation, life satisfaction, and depression severity in women aged 20-50 years who have experienced…
- Conditions
- Domestic Violence, Intimate Partner Violence, Depression, Activities of Daily Living
- Trial name
- NCT07454213
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Medipol University
Occupational Noise Exposure
OCCUPATIONAL NOISE AND CHEMICAL EXPOSURE EFFECTS ON AUDITORY AND VESTIBULAR FUNCTION
This study aims to investigate the effects of occupational noise exposure on hearing and auditory functions among individuals working in noisy environments.
- Trial name
- NCT07806123
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Noise Exposure, Noise-induced Hearing Loss
Non-Invasive System to Deliver Therapeutic Hypothermia for Protection Against Noise-Induced Hearing Loss
The goal of this interventional clinical study is to investigate the use of mild therapeutic hypothermia devices for preservation of sensory structures in the cochlea after noise exposure. The main aims of the study are: 1.
- Conditions
- Noise Exposure, Noise-induced Hearing Loss, Noise; Adverse Effect, Mild Therapeutic Hypothermia
- Trial name
- NCT06729632
- Testing
- Cold pack-delivered mild therapeutic hypothermia
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Restorear Devices LLC
Silicosis
DNA-damage Pathways in Workers Exposed to Silica (Caesar Stone)
Silicosis is well-known occupational disease caused by free crystalline silica (silicon dioxide) and is marked by inflammation and pulmonary fibrosis.
- Trial name
- NCT01329003
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
D001305, Auditory Fatigue
Fatigue and Hearing Performance of Healthy Volunteers Acutely Exposed to Occupational Noise ( FATIGAUDIT)
Occupational noise exposure is regulated by law, and protective measures are applied if the noise level exceeds 90 dB(A). The inferior exposure levels can cause an auditory fatigue which is defined as temporary and reversible…
- Conditions
- D001305, Auditory Fatigue, Noise Exposure, Environmental Noise
- Trial name
- FATIGAUDIT (NCT07604077)
- Testing
- 2h30 of noise exposure at 85 dB(A), 2 noise exposures of 66 minutes, 10 noise exposure cycles
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Meningococcal Infections
Investigating the Immunogenicity of a U.S.-Licensed Meningococcal Serogroup B Vaccine (Trumenba)
This study will investigate the breadth of protection against meningococcal disease in humans immunized with a newly FDA approved meningococcal B vaccine, trade name "Trumenba®" manufactured by Pfizer Vaccines.
- Trial name
- NCT02569632
- Testing
- Trumenba Vaccine (Wyeth/Pfizer Pharmaceuticals)
- Where
- 2 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Papillomavirus Vaccines
Occupational Exposure to Human Papilloma Virus (HPV) and Prophylactic Vaccination
Currently there are no standards for healthcare worker vaccination with the HPV, Gardasil-9 vaccine. For health care workers, the CDC only recommends for vaccination against hepatitis B, influenza virus, Measles, Mumps and…
- Trial name
- NCT03350698
- Testing
- Gardasil-9
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
COVID-19, Coronavirus Infection
Beaumont Health Large-scale Automated Serologic Testing for COVID-19
The purpose of this study is to determine how peoples' bodies respond to exposure to COVID-19. Employees of Beaumont Health in Michigan who are older than 18 years may be eligible to participate.
- Conditions
- COVID-19, Coronavirus Infection, Severe Acute Respiratory Syndrome Coronavirus 2
- Trial name
- BLAST COVID-19 (NCT04349202)
- Testing
- EUROIMMUN assay
- Where
- 2 sites in United States
- Volunteers
- 20,614 people, healthy volunteers welcome
- Sponsor
- Corewell Health East
Firefighter, Respiratory
Effect of Active Period Length of Firefighters on Respiratory and Climbing
The goal of this observational cross-sectional study is to examine the effect of the active period of firefighters in the units on respiratory functions and stair climbing performance.
- Conditions
- Firefighter, Respiratory, Climbing
- Trial name
- NCT05657626
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Asbestosis
Oscillation Mechanics of the Respiratory System Asbestos Exposed: Early Diagnosis
Inhalation of dust containing asbestos results in a process of interstitial pulmonary fibrosis called asbestosis. The Forced Oscillation Technique (FOT) evaluates the respiratory mechanics describing resistive, elastic and…
- Trial name
- NCT02280343
- Testing
- evaluated lung function
- Where
- Brazil
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin
Skin Cancer Among Outdoor Workers
This observational study examines skin cancer among workers who may have prolonged occupational exposure to sunlight. Long-term exposure to ultraviolet radiation from the sun is an important risk factor for several types of skin…
- Conditions
- Melanoma (Skin Cancer), Basal Cell Carcinoma of Skin, Squamous Cell Cancer of Head and Neck (SCCHN), Work Injury
- Trial name
- Skin Cancer Am (NCT07831083)
- Where
- Israel
- Volunteers
- 10,000 people
- Sponsor
- Assuta Medical Center
Industrial Hygiene, Epidemiology
Cancer Markers Associated With Occupational Exposure to Trichloroethylene
Background: Trichloroethylene (TCE) is a solvent used in many medical and industrial processes. TCE is a carcinogen (causes cancer) in rats, but its carcinogenicity in humans is unclear.
- Conditions
- Industrial Hygiene, Epidemiology, Neoplasms
- Trial name
- NCT00481611
- Where
- China
- Volunteers
- 125 people
- Sponsor
- National Cancer Institute (NCI)
Risk Reduction, Occupational Exposure
Aerosol Generation in Dental Clinics
The study examines 4 different methods to reduce dental bioaerosol spread in orthodontic procedures.
- Conditions
- Risk Reduction, Occupational Exposure, Dentist-Patient Transmission
- Trial name
- NCT05468099
- Testing
- Chlorhexidine mouthwash and Povidone-Iodine, High volume evacuator, High volume evactuator and saliva ejector
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Pesticide Safety
Reducing Farmworkers Exposure to Agricultural Chemicals
The goal of this project is to develop and test the effectiveness of a Lay Health Advisor program to teach migrant and seasonal farmworkers about pesticide safety in their homes.
- Trial name
- NCT00298649
- Testing
- Lay Health Advisor
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Occupational Health, Hazardous Material Handling
Drug Exposure Feedback and Education for Nurses' Safety
The goal of this research is to evaluate the efficacy of an audit and feedback intervention to improve personal protective equipment (PPE) use by nurses who handle hazardous drugs in the ambulatory oncology setting.
- Trial name
- DEFENS (NCT02283164)
- Testing
- Hazardous materials online education and study feedback
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- University of Michigan