Clinical trials: Exposure to Pollution
Asthma, COPD (Chronic Obstructive Pulmonary Disease)
Reducing Exposure With Air Cleaners and Technology
Fine particulate matter (PM2.5) is a type of air pollution made up of extremely tiny particles that can harm our health. Because PM2.5 particles are so small, they can travel deep into the lungs when we breathe.
- Trial name
- REACT (NCT07914010)
- Testing
- Air Cleaner, PM2.5 Monitor with Visual Air Quality Indicator, Educational Materials
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of California, Berkeley
Air Pollution, Acute Myocardial Infarction
Short-term Air Pollution Exposure and In-hospital Outcomes in Patients With Acute Myocardial Infraction
The aim of this study is to investigate whether or not short-term expose to air pollution is associated with in-hospital outcomes, such as mortality and morbidity.
- Conditions
- Air Pollution, Acute Myocardial Infarction, Percutaneous Coronary Intervention
- Trial name
- NCT02652182
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Nanjing Medical University
Lung Disease, Cancer
Biomarkers of Benzene Exposure in Inner City Residents
This study compares air pollution exposures of residents in a South Baltimore community next to major industry with those in a comparison community with much less industry nearby.
- Trial name
- NCT00014963
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pollution; Exposure, Hypertension
Solar Lighting to Reduce Indoor Air Pollution in Rural Uganda
This study evaluates the impact of a solar lighting system on kerosene lamp use, levels of indoor air pollution, and health in women living in rural Uganda.
- Conditions
- Pollution; Exposure, Hypertension, Pollution Related Respiratory Disorder
- Trial name
- NCT03351504
- Testing
- Solar lighting system
- Where
- 2 sites in United States, Uganda
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Air Pollution, Pollution; Exposure
Modification of Ambient Air Pollution Exposure and Cardiopulmonary Outcomes by Socioeconomic Status and Nutrition
The goal of this observational study is to compare the effects of air pollution exposure and nutrition between neighborhoods with high and low social vulnerability scores.
- Conditions
- Air Pollution, Pollution; Exposure, Nutrition, Healthy
- Trial name
- SENSE (NCT05843370)
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Exposure to Environmental Pollution, Non-occupational
The Interaction of Social Factors With Air Pollution
Purpose: The purpose of this protocol is to understand how social factors such as psychosocial stress may modify how people respond to air pollution.
- Trial name
- SOZIAL (NCT02206750)
- Testing
- Clean Air, Ozone
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Pollution; Exposure, Smoke Inhalation
Controlled Exposure of Healthy Nonsmokers to Secondhand and Thirdhand Cigarette Smoke
This study compares the health effects of dermal and inhalational exposure to thirdhand cigarette smoke to those of inhalational exposure to secondhand cigarette smoke in healthy, adult nonsmokers.
- Conditions
- Pollution; Exposure, Smoke Inhalation, Exposure to Pollution
- Trial name
- THS04 (NCT04013256)
- Testing
- Cigarette Smoke
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Allergic Contact Dermatitis, Metal Allergy
Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases
The goal of this clinical trial is to collect environmental, bio-humoral, and clinical data derived from patients with allergic contact dermatitis (ACD) and systemic metal allergic syndromes related to the exposure to heavy…
- Conditions
- Allergic Contact Dermatitis, Metal Allergy, Food Allergy, Nickel Sensitivity
- Trial name
- MATRIOSKA (NCT06529913)
- Testing
- Collection of environmental, biological, and clinical data
- Where
- 2 sites in Italy
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Asthma in Children, Pollution; Exposure
Evidence Driven Indoor Air Quality Improvement
The aim is to identify the underlying disease mechanisms driving specific asthma phenotypes as well as certain disease outcomes and their relation to impaired indoor air quality.
- Trial name
- NCT05992389
- Where
- Croatia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Srebrnjak
Pollution; Exposure, Environmental Exposure
The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing
To quantify health effects of synergizing chemical and biological pollutants in a targeted population setting, i.e., school-aged children. Indoor air pollutants will be monitored within the classrooms with high end sensors.
- Conditions
- Pollution; Exposure, Environmental Exposure, Childhood Asthma, Childhood
- Trial name
- SynAir-Child (NCT05105386)
- Testing
- SynAir-Child
- Volunteers
- 3,000 people
- Sponsor
- National and Kapodistrian University of Athens
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Pollution Related Respiratory Disorder, Pollution; Exposure
Lung and Heart Function Across Decades of Life in Health
The main objective of this study is to develop baseline "normal" reference values of both lung and heart function for healthy adults within the age range relevant to the United States Veteran population who served in the…
- Conditions
- Pollution Related Respiratory Disorder, Pollution; Exposure, Dyspnea, Cardiopulmonary
- Trial name
- NCT07641413
- Testing
- Healthy control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cardiovascular Diseases
Cleaner Air for Better Cardiac Biomarkers
This pilot project is a randomized, double-blind, sham-controlled trial investigating whether in-home air pollution reductions using portable air cleaners (PACs) can decrease circulating concentrations of biomarkers of…
- Trial name
- NCT05379400
- Testing
- Portable air cleaner (PAC)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- NYU Langone Health
Cognition
Indoor Air Quality Monitoring and Impact on Children's Health
This study aims at understanding the relation between indoor air quality in schools, including both chemical and microbiological determinants, and cognition in children by gathering data across different parts of Europe
- Trial name
- LEARN (NCT06197477)
- Testing
- OurAir SQ 1750 - Mobile Air Purification System for indoor
- Where
- Belgium
- Volunteers
- 900 people
- Sponsor
- Hasselt University
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Lungs on Fire: Wildfire Smoke, Incident Diseases, Susceptible Populations, and Community Values in Canada
Wildfire smoke (WFS) is the leading climate-related risk in Canada and the main source of harmful air pollution. While short-term breathing problems caused by smoke are well known, there is limited knowledge on how repeated…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease (COPD), Lung Cancer
- Trial name
- LoF (NCT07536178)
- Testing
- Woodsmoke (Lodgepole Pine) exposure, Filtered air exposure
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Tobacco Smoke Pollution
Reduction of Environmental Tobacco Smoke (ETS) Exposure at Home: the BIBE Study
Main objective: to determine the effectiveness of a brief opportunist educational performance directed to the parents who smoke -- inside the context of programmed visits of paediatrics in primary care -- to reduce the exposure…
- Trial name
- BIBE (NCT00788996)
- Testing
- Brief intervention based in clinical practice guide
- Where
- Spain
- Volunteers
- 552 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Environmental Exposure
Change in Knowledge After Receiving Personal Air Pollution Results
Personal exposure to air pollution results from the interaction of individual time-activity patterns with levels of air pollution that vary over time and space.
- Trial name
- NCT05160948
- Testing
- Informational Report
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Risk Factors for Respiratory and Cardiovascular Disease
Influence of Indoor Air Filtration Strategies on Occupant Health Indicators
The purpose of this study is to evaluate whether two different central air purification technologies reduce air pollutant exposure and beneficially influence health as evaluated with a suite of biological markers related to…
- Trial name
- NCT02769208
- Testing
- Central air handling unit air purification technologies
- Where
- China
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Feng Li
PreDiabetes
Cleaner Air for Lower Cardiometabolic Risk
The purpose of this interventional sham-controlled pilot study is to study the effects of using portable air cleaners (PACs) in outpatient adults with prediabetes.
- Trial name
- NCT05994937
- Testing
- PAC with HEPA filter intact, PAC with HEPA filter removed
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- NYU Langone Health