Clinical trials: Exposure to Pollution
Pollution; Exposure, Glucose Intolerance
Environmental Toxicants Avoidance Study
This study is designed to test whether non-persistent environmental chemicals (PECs) are elevated in people with glucose dysregulation.
- Conditions
- Pollution; Exposure, Glucose Intolerance, Glycemic Control
- Trial name
- NPETA-GD (NCT04821752)
- Testing
- Avoidance Education
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bastyr University
Cardiovascular System, Health
Acute Effects of Meteorological Factors and Air Pollution on Cardiovascular Health
The goal of this observational study is to analyze the acute effects of meteorological factors and air pollution on cardiovascular system. The main question it aims to answer is: 1.
- Trial name
- NCT06663267
- Testing
- NOT
- Where
- China
- Volunteers
- 350,000 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Hangzhou Normal University
Pulmonary Arterial Hypertension, Air Pollution
The Risk of Adverse Pregnancy Outcomes for Long-term Exposure to Air Pollution in Pregnant Patients With Pulmonary Hypertension
With economic development and rapid urbanization, air pollution has become an increasingly severe public health concern. The risk of adverse pregnancy outcomes is significantly elevated for pregnant women complicated by pulmonary…
- Conditions
- Pulmonary Arterial Hypertension, Air Pollution, Maternal Outcome
- Trial name
- NCT07164157
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Wei Huang
Asthma
Asthma & Exposure to Peaks in Particulate Air Pollution
We are testing the following two hypotheses: 1) Peaks in hourly exposures to airborne particulate matter (PM) of outdoor origin will be more closely associated with acute asthmatic responses to particles than 24-hour average…
- Trial name
- NCT00013728
- Volunteers
- 24 people
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Occupational Exposure
Occupational Exposure to Dust and the Relationship With the Respiratory Symptoms, Lung Function Among Construction Workers of the University of Malaysia Sabah (UMS)
Background The respiratory tract often becomes the site of injury from occupational exposure. All construction sites generate high levels of dust, typically from concrete, silica, asbestos, cement, wood, stone, sand and…
- Trial name
- NCT05226273
- Testing
- no intervention
- Where
- Malaysia
- Volunteers
- 152 people
- Sponsor
- Universiti Malaysia Sabah
Innate Inflammatory Response, Vaccination
PFAS Exposure and Immune Response to Vaccination in Adults
This clinical trial aims to investigate how exposure to Perfluorononanoic acid (PFNA), a type of per- and polyfluoroalkyl substance (PFAS), affects the immune response to the standard tetanus and diphtheria (Td) vaccine.
- Conditions
- Innate Inflammatory Response, Vaccination, Diphtheria, Tetanus
- Trial name
- NCT06588530
- Testing
- TENIVAC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Air Pollution
The Effect of Juice Types on the Responses to Air Pollution
The study hypothesis is that drinking different juices will affect the body's responses to air pollution. Subjects will be exposed to air pollution during a 2-hour car ride on the NJ (New Jersey) Turnpike.
- Trial name
- NCT02027415
- Testing
- Beet juice, Orange juice
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Lung Cancer, High-Risk Cancer
Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration
Lung cancer is the leading cause of mortality in the world, and also in Taiwan.Despite the researches and availability in new therapies, it causes the highest mortality and is one of the most preventable cancers as well.
- Conditions
- Lung Cancer, High-Risk Cancer, Smoking, Pollution; Exposure
- Trial name
- TRIO (NCT05557487)
- Testing
- Low dose computed tomography
- Where
- 7 sites in Taiwan
- Volunteers
- 6,618 people, healthy volunteers welcome
- Sponsor
- Gee-Chen Chang
Allergic Rhinitis
Controlled Exposure to Diesel Exhaust in Subjects With Allergic Rhinitis
Proximity to traffic, particularly to diesel-powered heavy-duty vehicles, has been associated with inducing and enhancing allergies in children and adults.
- Trial name
- DALLER (NCT01617330)
- Testing
- Bronchoscopy
- Where
- Sweden
- Volunteers
- 14 people
- Sponsor
- University Hospital, Umeå
Respiratory Conditions Due to Unspecified External Agent
Anti-pollution Effects of AP Green Tea Extracts
The objective of this clinical trial is to evaluate the anti-pollution effects of AP green tea extracts in subjects with discomforts related to the respiratory system by prolonged exposure to particulate matter in air pollution
- Trial name
- NCT04340375
- Testing
- AP green tea extracts
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
COPD Bronchitis, Pollution Related Respiratory Disorder
Effect of the Inhaled Triple Therapies Over the Small Airway in Biomass Exposure
This phase IV randomized controlled clinical trial intend to compare the effect of three close standard inhaled triple therapies and one close standard inhaled double therapy on the small airway in patients with Chronic…
- Trial name
- NCT06571942
- Testing
- Vilanterol / Umeclidinium (25/62.5 mcg), Fluthicasone / Vilanterol / Umeclidinium (100/25/62.5 mcg), Beclomethasone / Formoterol / Glycopyrronyum 100/6/12.5 mcg
- Where
- Mexico
- Volunteers
- 128 people
- Sponsor
- National Institute of Respiratory Diseases, Mexico
Cardiovascular Function, Genotoxicity
Health Effects of Occupational Exposure to Combustion Particles - a Study on Volunteers Performing as Train Conductors
Ambient air pollution is a complex mixture of gaseous pollutants and particulate matter (PM). PM has a recognized important role in human health.
- Trial name
- BioTrack (NCT03104387)
- Testing
- Electric train, Diesel train
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Air Pollution Exposure, Heart Rate
Assessing the Health Impact of Indoor Air Purification Using Health Data Obtained From Apple Watch Wearers
This study aims to use the Apple Watch health metrics to assess short-term physiological responses in a randomized, double-blind, crossover real-world indoor purification intervention.
- Conditions
- Air Pollution Exposure, Heart Rate, Resting Heart Rate, HRV
- Trial name
- NCT07477834
- Testing
- Real Filtration
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- New York University Abu Dhabi
Cardiovascular System, Respiratory System
Acute Health Effects of Traffic-Related Air Pollution Exposure
This study aims to assess the effects of acute exposure to traffic-related air pollution and the underlying mechanisms.
- Trial name
- NCT04153539
- Testing
- Walking along a busy road, Walking in a traffic-free park
- Where
- China
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Fudan University
Exposure to Pollution
Chemometers to Determine the Environmental and Human Exposome by Mixtures of Pollutants
Motivation of this study Human life is full of chemicals: They support the provision of cure, clothes, shelter, transportation and even nourishment of the world population.
- Trial name
- EXPOSO-METER (NCT05927077)
- Testing
- planned surgery for weight reduction
- Where
- Germany
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Helmholtz Centre for Environmental Research - UFZ
Environmental Exposure, Ozone
Lung Mucus Hypersecretion and NQO1
The research plan proposes translational studies in relevant animal models and human subjects in order to identify host (genetic) susceptibility factors that confer vulnerability to the prototypal air pollutant, ozone.
- Conditions
- Environmental Exposure, Ozone, Air Pollution, Genetic Susceptibility
- Trial name
- NCT00729352
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Pollution; Exposure
Effects of Transportation Choices on Commuter Health
The primary project objective is to investigate how an individual's choices influence personal exposures to traffic-related air pollutants (TRAPs) and the corresponding acute health effects.
- Trial name
- ETCH (NCT05758714)
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- UConn Health
Multiple Sclerosis, Relapsing-Remitting, Environmental Exposure
the EXPOSITION Study
This is a cross-sectional study to evaluate the variation of biological biomarkers of oxidative stress and inflammation in response to the external exposome, in people with Multiple Sclerosis (pwMS).The objective is to study the…
- Conditions
- Multiple Sclerosis, Relapsing-Remitting, Environmental Exposure, Lifestyle Factors
- Trial name
- EXPOSITION (NCT06325358)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Pavia
Exposure to Pollution, Glucocorticoid Resistance
Diesel Exhaust Induces Glucocorticoid Resistance
The investigators are studying the effects of exposure to diesel exhaust on lung inflammation in the presence and absence of an inhaled corticosteroid.
- Trial name
- DIGR (NCT03615742)
- Testing
- Budesonide, Filtered Air, Diesel Exhaust
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Women Who Gave Birth at Dijon and Besançon CHUs Between 2005 and 2009
Relationship Between Multi-exposure to Noise and Air Pollution and the Onset of Hypertension Disorders During Pregnancy
This retrospective study aimed to analyse the relationship between multi-exposure to noise and air pollution the onset of hypertension disorders during pregnancy It will be conducted in 2650 mothers who gave birth at Dijon or…
- Trial name
- HTA-BQuA (NCT03261245)
- Where
- 2 sites in France
- Volunteers
- 2,650 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon