Clinical trials: Extracorporeal Circulation
Cardiogenic Shock, Myocardial Infarction
Quality of Care in Centers Providing Extracorporeal Membrane Oxygenation
Cardiac arrest centers are specialized in treating critically ill patients with severe cardiovascular diseases, such as cardiac arrest, cardiogenic shock or acute myocardial infarction.
- Conditions
- Cardiogenic Shock, Myocardial Infarction, Cardiac Arrest, Extracorporeal Circulation; Complications
- Trial name
- NCT05331001
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Shock, Cardiogenic, Cardiac Arrest
Hemodynamic Comparison of Peripheral and Central VA ECMO.
The goal of this clinical trial is to monitor hemodynamic differences between central veno-arterial extracorporeal membrane oxygenation (VA ECMO) and peripheral VA ECMO.
- Conditions
- Shock, Cardiogenic, Cardiac Arrest, Extracorporeal Circulation; Complications, Hemodynamics Instability
- Trial name
- RECOVERY (NCT05669183)
- Testing
- Veno-arterial extracorporeal membrane oxygenation
- Where
- China
- Volunteers
- 136 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Residual Cardiac Output During PVA-ECMO
Use of Exhaled Carbon Dioxyde for Monitoring the Native Cardiac Function During Mechanical Circulatory Support With Venoarterial By-pass in Intensive Care Unit
Cardiogenic shock, the most severe form of acute heart failure, is a critical situation where the body cells lack of oxygen because of cardiac dysfunction.
- Trial name
- CAPNOECMO (NCT03323268)
- Testing
- PetCO2 monitoring
- Where
- France
- Volunteers
- 39 people
- Sponsor
- University Hospital, Montpellier
Extra Corporeal Membrane Oxygenation, Decanulated Alive
Modeling of Intracerebral Vascularization After Extracorporeal Membrane Oxygenation in Children
Extra corporeal membrane oxygenation (ECMO) is a transient supplementation technique that alleviates hemodynamic and ventilatory failure.
- Trial name
- MoVa-ECMO (NCT05237232)
- Testing
- Magnetic Resonance Angiography (MRA) additional acquisition time, Modeling cerebral vascularization
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Extracorporeal Circulation, Cardiac Surgery
Priming of Cardiopulmonary Bypass With Hydroxyethyl Starch 130/0.4 or Sodium Chloride 0.9% : Pilot Study in Adult Elective Conventional Cardiac Surgery
Best priming for cardiopulmonary bypass in cardiac surgery is unknown. Efficacy and toxicity of Hydroxyethyl Starch 130/0.4 used in this context are uncertain.
- Trial name
- OPTIMUS-PRIME (NCT02906514)
- Testing
- Non balanced Hydroxyethyl starch 130/0.4 (Voluven®, Fresenius), Sodium Chloride 0.9% (Fresenius)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Patients Requiring Cardiac Surgery
Contribution of Preoperative Biological Data in Risk Assessment in Cardiac Surgery in Addition to the EuroSCORE (EuroSCOREbio)
In cardiac surgery, the assessment of operative risk and quality of care is a major challenge for both patient, and surgical team.
- Trial name
- EuroSCOREbio (NCT02783781)
- Testing
- Cardiac surgery (extracorporeal circulation; beating heart)
- Where
- 10 sites in France
- Volunteers
- 9,500 people
- Sponsor
- University Hospital Center of Martinique
Coronary Artery Bypass
Comparison of Minimal Versus Conventional Extracorporeal Circulation in Coronary Surgery
The aim of this study is to assess the effect of minimal (MiECC) versus conventional (CECC) extracorporeal circulation on perfusion characteristics and remote end-organ protection (lungs, brain, kidneys, liver, stomach…
- Trial name
- NCT01603589
- Testing
- Coronary artery bypass grafting with the use of minimal invasive extracorporeal circulation, Coronary artery bypass grafting under conventional extracorporeal circulation
- Where
- Greece
- Volunteers
- 150 people
- Sponsor
- AHEPA University Hospital
Coagulopathy
Quantification of Thrombocytes Number and Function in Patients Undergoing Prolonged Extracorporeal Circulation
Prolonged extracorporeal circulation (ECC) for cardiac surgery results in coagulation abnormalities, most of which related to the direct, time dependent effect of the polymer tubing and the pump rollers on the thrombocytes.
- Trial name
- CPB-PLT-FNCT (NCT02771223)
- Volunteers
- 20 people
- Sponsor
- Rambam Health Care Campus
Scheduled Cardiac Surgery With Extracorporeal Circulation, Vasoplegic Syndrome
Evaluation of the Superiority of VAsopressin Versus NOradrenaline in the Management of Patients at Risk of Kidney Failure Undergoing Cardiac Surgery With Extracorporeal Circulation
This is a randomized, double blind, multicenter study following surgery with extracorporeal circulation to compare blood pressure optimization with vasopressin versus noradrenaline.
- Trial name
- NOVACC (NCT05568160)
- Testing
- Vasopressin, Norepinephrine, Collection of clinical data
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Centre Hospitalier Universitaire Dijon