Clinical trials: Extracorporeal Membrane Oxygenation Complication
Patients With Extracorporeal Membrane Oxygenation
The Incidence and Risk Factors of Biliary Complications in Patients With ECMO
By confirming the incidence of biliary tract complications in adult patients aged 18 years or older who received extracorporeal membrane oxygenation , and measuring the duration of application of extracorporeal membrane…
- Trial name
- NCT04963322
- Testing
- extracorporeal membrane oxygenation therapy
- Where
- South Korea
- Volunteers
- 549 people
- Sponsor
- Kim Hee Young
Extracorporeal Membrane Oxygenation Complication, Outcome, Fatal
Therapy and Outcome of Prolonged Veno-venous ECMO Therapy of Critically Ill ARDS Patients.
In the context of the coronavirus (COVID-19) pandemic, healthcare systems worldwide faced an unprecedented shortage of severe ARDS.
- Trial name
- NCT05338593
- Testing
- Outcome
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Goethe University
Compartment Syndrome of Leg, Extracorporeal Membrane Oxygenation Complication
Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients
Acute compartment syndrome (ACS) is a surgical emergency that can develop in patients on extracorporeal membrane oxygenation (ECMO).
- Conditions
- Compartment Syndrome of Leg, Extracorporeal Membrane Oxygenation Complication, Limb Ischemia, Limb Ischemia, Critical
- Trial name
- VA-ECMO (NCT05830721)
- Testing
- MY01 + Standard of Care, 14-Gauge Slit Catheter + Standard of Care, Standard of Care
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Johns Hopkins University
Extracorporeal Membrane Oxygenation Complication
Use of Nafamostat Mesilate for Anticoagulation in Patients With ECMO
The purpose of this study is to evaluate the effectiveness and safety of nafamostat mesilate compared with unfractionated heparin for anticoagulation in patients with ECMO after cardiac surgery.
- Trial name
- NCT06276010
- Testing
- nafamostat mesilate, unfractionated heparin group
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xiaotong Hou
Extracorporeal Membrane Oxygenation Complication
Distal Perfusion Timing, Early or Conservative, to Prevent Limb Ischemia During Peripheral VA-ECMO
Peripheral VA-ECMO is widely used in refractory cardiogenic shock patients as a salvage therapy. In most cases, the femoral artery and vein are used for the vascular approach.
- Trial name
- DECIDE-ECMO (NCT05698628)
- Testing
- Distal perfusion catheterization
- Where
- South Korea
- Volunteers
- 400 people
- Sponsor
- Min-Seok Kim
Extracorporeal Membrane Oxygenation Complication
BivaLirudin versUS Heparin in Extracorporeal Membrane Oxygenation
The goal of this open label randomised clinical trial is to compare Bivalirudin versus Heparin for anticoagulation in patients requiring extracorporeal membrane oxygenation support.
- Trial name
- BLUSH (NCT05959252)
- Testing
- Unfractionated heparin, Bivalirudin
- Where
- Australia
- Volunteers
- 80 people
- Sponsor
- Sydney Local Health District
COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication
Correlation Between PaCO2 and Respiratory Effort in Patients With COVID-19 With Extracorporeal Membrane Oxygenation
Excessive respiratory effort may cause self-inflicted lung injury (SILI) and inspiratory muscle injuries , stimulate desynchronization between the patient and ventilator , and worsen the perfusion of extrapulmonary organs .
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation Complication, Respiratory Effort-Related Arousal
- Trial name
- NCT05882474
- Testing
- PaCO2
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Peking Union Medical College Hospital
Acute Respiratory Distress Syndrome, Nosocomial Infection
Nosocomial Infections in ECMO Patients
Nosocomial Infections (NI) are a common and dreadful complication for patients suffering from Acute Respiratory Distress Syndrome (ARDS) treated with Extracorporeal Membrane Oxygenation (ECMO).
- Conditions
- Acute Respiratory Distress Syndrome, Nosocomial Infection, Extracorporeal Membrane Oxygenation Complication
- Trial name
- INF-ECMO (NCT05566665)
- Testing
- Collection of blood and bronchoalveolar samples to study Pharmacokinetics of ceftazidime/avibactam, meropenem/varbobactam, ceftolozane/tazobactam, or cefiderocol
- Where
- 2 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Policlinico Hospital
Out-of-hospital Cardiac Arrest (OHCA), ECMO Treatment
Hypothermia Versus Normothermia After Extracorporeal Cardiopulmonary Resuscitation for Out-of-hospital Cardiac Arrest
The SAVE-J NEUROTHERM trial is a cluster randomized trial that evaluated and compared the mortality risk, neurological outcomes, and adverse events between patients who underwent hypothermia and those who underwent normothermia…
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), ECMO Treatment, Temperature, Post Cardiac Arrest Syndrome
- Trial name
- J-NEURO (NCT06776549)
- Testing
- Temperature control
- Where
- 29 sites in Japan
- Volunteers
- 468 people
- Sponsor
- Kagawa University
ARDS, Human, Acute Kidney Injury
Regional Citrate Anticoagulation for RRT During V-V ECMO
Anticoagulation is an essential component of all extracorporeal therapies. Currently locoregional citrate anticoagulation is the recommended technique for continuous renal replacement therapy (CRRT).
- Trial name
- CRRT ECMO (NCT05148026)
- Testing
- Unfractionated heparin + RCA first, Unfractionated heparin first
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- University of Milano Bicocca