Clinical trials: Extraction, Tooth
Acute Pain
Tramadol/Diclofenac Fixed-dose Combination Phase III Trial in Acute Pain After Third Molar Extraction
This study evaluated a new drug fixed-dose combination tablet (FDC) called tramadol/diclofenac at two different strengths (fixed doses of 25 milligrams [mg] of tramadol and of diclofenac or of 50 mg each).
- Trial name
- NCT03714672
- Testing
- Tramadol/Diclofenac 50/50, Tramadol/Diclofenac 25/25, Tramadol 50
- Where
- 8 sites in Mexico
- Volunteers
- 1,151 people
- Sponsor
- Grünenthal GmbH
Tooth Avulsion
Efficacy of a Collagen Hemostatic Dressing After Tooth Extraction
This study is a multicentric randomised (2 groups, ratio 1:1) Post Market Clinical Follow-up trial. 38 subjects (teeth) requiring a simple tooth extraction or multiple tooth extraction on the same quadrant and taking curative or…
- Trial name
- NCT05174858
- Testing
- Hemostatic dressing ETIK COLLAGENE, Comparator
- Where
- 2 sites in France
- Volunteers
- 38 people
- Sponsor
- ACTEON Group
Teeth Staining
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains) Over 8 Weeks of Unsupervised Use.
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic…
- Trial name
- NCT07219342
- Testing
- Toothpaste
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Jaw, Edentulous, Partially
Study to Compare Survival for ASTRA TECH Implant System, OsseoSpeed™ Implants Following Immediate Loading in Extraction Sockets Versus Immediate Loading in Healed Ridges
The purpose of this study is to evaluate survival for ASTRA TECH Implant System, OsseoSpeed™ implants following immediate loading in extraction sockets versus immediate loading in healed ridges.
- Trial name
- NCT00710944
- Testing
- ASTRA TECH Implant System, OsseoSpeed™
- Where
- 4 sites in United States, Belgium and 2 more
- Volunteers
- 132 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Gingivitis, Dental Plaque
A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal
The main goal of this study is to evaluate and compare the efficacy of an on-market dentifrice containing 67 percent (%) sodium bicarbonate and 0.31% sodium fluoride to a reference regular fluoride dentifrice on treating gingival…
- Trial name
- NCT05654662
- Testing
- Corsodyl Original Dentifrice, Colgate Cavity Protection Dentifrice
- Where
- United Kingdom
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- HALEON
Tooth Extraction
A Clinical Study on the Efficacy and Safety of Lando® Absorbable Collagen Membrane in Oral Bone Repair
This is a randomized, paralleled, control trial to validate the effectiveness and safety of Lando® absorbable collagen membrane for oral bone repair.
- Trial name
- NCT03464786
- Testing
- Lando® absorbable collagen membrane, Geistlich Bio-Gide resorbable bilayer membrane
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Shenzhen Lando Biomaterials Co., Ltd.
Teeth Staining
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Sensitive Whitening Toothpaste, Containing 5% KNO3 (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic Stains Over 4 Weeks of Unsupervised Use.
The Purpose of This Research Study is to Compare the Effectiveness of a Non-fluoride Whitening Toothpaste (Test) to That of a Non-whitening Fluoride Toothpaste (Negative Control) in Improving Tooth Whiteness (Removal of Extrinsic…
- Trial name
- NCT07761715
- Testing
- Toothpaste
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Boka LLC
Dry Socket
Impact of Treatment With ALVEOGYL in Patients With Post-extraction Dry Socket
Alveogyl (Septodont, Saint-Maur-des-Fossés - France) is a Medical Device used as dressing in case of dry socket. ALVE study is a clinical investigation measuring Alveogyl performance and safety in patients with post-extraction…
- Trial name
- NCT05536115
- Testing
- Alveogyl
- Where
- 16 sites in France, India
- Volunteers
- 120 people
- Sponsor
- Septodont
Dental Pain
Study of Naproxen Capsules to Treat Dental Pain
The purpose of the study is to determine whether Naproxen Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT01229228
- Testing
- Naproxen Test, Naprosyn
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- Iroko Pharmaceuticals, LLC
Tooth Loss
An RCT Comparing Xenograft and Allograft for Ridge Preservation
To compare the effectiveness of demineralized freeze-dried bone allograft + cross-linked collagen membrane with xenograft + non-cross-linked collagen membrane for posterior extraction socket ridge preservation.
- Trial name
- NCT02330523
- Testing
- allograft + x-link collagen membrane, xenograft + non-x-link collagen
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- McGuire Institute
Tooth Loss
Comparison of Straumann BoneCeramic vs. Allograft Bone in Extraction Sockets
The primary objective of this study is to evaluate the implant stability at the time of abutment placement on implants placed in healed extraction sockets treated with Straumann BoneCeramic (SBC) versus Freeze Dried Bone…
- Trial name
- NCT00782236
- Testing
- Bone Graft Material
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Institut Straumann AG
Acute Post Operative Pain, Third Molar Extraction Surgery
A Phase 1 Study of ARC-001 in Participants Undergoing Third Molar Extraction
The study will test the investigational product gel against placebo (which contains no active ingredient) to determine if it is safe after wisdom tooth extraction. The main questions the study will answer are: 1.
- Trial name
- NCT06864884
- Testing
- ARC-001
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Arcato Laboratories, Inc.
Post-operative Pain
Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
- Trial name
- NCT01229449
- Testing
- Ibuprofen/acetaminophen, Ibuprofen/acetaminophen (higher dose), Nurofen Plus®
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Reckitt Benckiser LLC
Jaw, Edentulous
Multicenter Study to Evaluate the Clinical Outcome of the OmniTaper EV Implant in Single Tooth Restorations
This clinical study, funded by the company Dentsply Sirona, is being carried out to see if the newly developed tooth implant "OmniTaper EV" is safe, effective and functions as intended when replacing a lost or removed tooth.
- Trial name
- NCT05355792
- Testing
- OmniTaper EV implants
- Where
- 6 sites in Germany, Switzerland and 1 more
- Volunteers
- 139 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Dental Plaque
Plaque Removal Efficacy of a U-Shaped Sonic Power Toothbrush in Children
The objective of this single-use, examiner blinded, randomized, two-period, cross-over, IRB-approved clinical study is to evaluate the safety and plaque removal efficacy of AutoBrush®, a new children's 360° sonic toothbrush…
- Trial name
- NCT06300073
- Testing
- Experimental: U-shaped Power Toothbrush
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Lander Enterprises, LLC
TEETH EXTRACTION
Ridge Preservation Using a Ossix™ Bone vs Bio-Oss® Collagen
This randomized, parallel design, controlled study will assess the histologic healing of this Ossix™ Bone in humans and compare it to a Bio-Oss® Collagen that is well researched. Subjects will be enrolled into 2 groups.
- Trial name
- NCT04338516
- Testing
- Ossix™ Bone, Bio-Oss® Collagen
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Datum Dental LTD
Stain Removal Efficacy
Extrinsic Tooth Whitening Evaluation of a Whitening Toothpaste
This randomized, examiner-blind, parallel-group clinical study evaluated the effectiveness of a whitening toothpaste compared with a control toothpaste in removing extrinsic tooth stain over six weeks of twice-daily unsupervised…
- Trial name
- NCT07428603
- Testing
- Whitening Test Dentifrice (Code 826), Control dentifrice (Code 378)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- Church & Dwight Company, Inc.
Tooth Extraction Site Healing
Effect of a Bioactive Mineral-Ionic Mouthrinse on Periodontal Soft Tissue Healing
This randomized, double-blinded clinical trial was designed to evaluate the effects of a bioactive mineral-ionic mouthrinse (THERAVEX® Total Oral Care Plus) on postoperative healing and patient comfort following simple tooth…
- Trial name
- Bioactive Mine (NCT07611123)
- Testing
- Normal Saline, chlorhexidine (CHX), Theravex Bioactive Solutions (Tissue Care Plus and Oral)
- Where
- Saudi Arabia
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Biointelligent Technology Systems SL
Dental Pain
Maxi-Analgesic Phase 2 Study to Compare the Analgesic Effects in Different Dosing Groups to Treat Teeth Extraction Pain
The aim of the study is to examine the dose response relationship in the treatment of dental pain (teeth extraction) for the different potential doses of the investigational drug, i.e.
- Trial name
- NCT01104844
- Testing
- Full Dose Strength, Quarter dose strength, Half dose strength
- Where
- United States
- Sponsor
- AFT Pharmaceuticals, Ltd.
Tooth Extraction, Tooth Fractures
Efficacy and Safety Evaluation Study of Implants With Periodontal Ligament
The goal of this clinical trial is to evaluate the efficacy and safety of periodontal ligament-integrated implants placed via residual periodontal ligament tissue in extraction sockets in adult patients (aged 18 and older)…
- Conditions
- Tooth Extraction, Tooth Fractures, Dental Caries, Tooth Dislocation
- Trial name
- NCT07302581
- Testing
- Periodontal Ligament-Integrated Implant
- Where
- 2 sites in Japan
- Volunteers
- 6 people
- Sponsor
- OrganTech, Inc.