Clinical trials: Extraction, Tooth
Tooth Extraction
Alveolar Ridge Preservation in Molar Extraction Sockets With an Open Healed Collagen Membrane: A Randomized Clinical Trial.
The resorption of alveolar ridge after tooth extraction develop difficulty in restoring the extraction area with implant or bridge.
- Trial name
- NCT04802148
- Testing
- membrane guided regeneration, collagen plug
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Alveolar Ridge Preservation, Implant Therapy
Alveolar Ridge Preservation With Cortico-cancellous Porcine Bone
Observational, prospective study conducted on patients requiring tooth extractions followed by ARP and subsequent implant placement.
- Conditions
- Alveolar Ridge Preservation, Implant Therapy, Tooth Extraction Site Healing
- Trial name
- NCT06970184
- Testing
- tooth extraction with alveolar ridge preservation, Implant placement
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- University of Pisa
Third Molar Extraction, Impacted Third Molar Tooth
Use of Erbium Laser for Extraction of the Third Molars
A comparative analysis of the effectiveness of the erbium laser with the wavelength of 2.94 µm and traditional instruments in the extraction of the impacted lower third molars will be performed.
- Trial name
- NCT05540015
- Testing
- Third molar extraction by cutting and rotary tools, Third molar extraction by erbium laser with wavelength 2.94 nm
- Volunteers
- 60 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Diabetes Mellitus, Type 2, Surgery
Piezosurgical vs Conventional Exodontia Surgery in Healthy and Patients With Diabetes Mellitus Type 2
This study will evaluateand compare intraoperative and postoperative clinical parameters related to discomfort and wound heeling, as well as laboratory wound healing parameters after piezosurgical and conventional surgery…
- Conditions
- Diabetes Mellitus, Type 2, Surgery, Tooth Extraction Status Nos
- Trial name
- PCSDMT2 (NCT06046976)
- Testing
- piesosurgical extraction, conventional extraction
- Where
- Serbia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Periodontitis, Dental Caries
Comparison of Topical Analgesic With Saline Rinses in Post Extraction Healing
The aim of this study is to determine the beneficial effect of mouth rinses, both topical analgesic and saline regimens as an adjuvant therapy in the presence of standard prescription of post-operative pain killers on the…
- Conditions
- Periodontitis, Dental Caries, Hypertension
- Trial name
- NCT02921165
- Testing
- analgesic mouth rinses (dissolved Aspirin), Normal saline rinses.
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Aga Khan University
Dental Pain
Safety and Efficacy Study of XPF-001 to Treat Pain Following Wisdom Tooth Extraction
The purpose of this trial is to determine if XPF-001 is effective for the treatment of pain following third-molar/wisdom tooth extraction.
- Trial name
- NCT00954356
- Testing
- XPF-001
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Xenon Pharmaceuticals Inc.
Periodontal Pocket, Swelling Lips & Face
The Efficacy of Autogenous Dentin Graft in Mandibular Wisdom Tooth Extraction
The study aimed to investigate clinical effect of autogenous dentin graft on patients following mandibular wisdom tooth extraction.
- Conditions
- Periodontal Pocket, Swelling Lips & Face, Trismus, Pain, Acute
- Trial name
- NCT06073639
- Testing
- Autogenous dentin graft
- Where
- Vietnam
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Alveolar Bone Preservation, Bone Graft
Clinical Study of Injectable Ceramics Bone Graft Substitute Containing rhBMP-2
This is a prospective, outcomes assessor-blinded, randomized study to evaluate the efficacy and safety of "Inject BMP(Injectable Ceramics Bone Graft Substitute Containing rhBMP-2)" for socket preservation after extraction of a…
- Trial name
- rhBMP-2 (NCT02714829)
- Testing
- Inject BMP, ExcelOS-inject
- Volunteers
- 88 people
- Sponsor
- BioAlpha Inc.
Endodontically Treated Teeth, Endodontical Retreatment
Broken Instrument Removal
The aims of this retrospective analysis are (1) to evaluate the success rate of a non-surgical retreatment of teeth with broken file instrument into the canal using ultrasounds, microscope and a modified spinal needle, (2) to…
- Trial name
- NCT05128266
- Testing
- Endodontical Retreatment
- Volunteers
- 161 people
- Sponsor
- Catholic University of the Sacred Heart
Impacted Third Molar Tooth
Extraction of Impacted 3rd Molars, Can Bone Support of the Second Molar be Promoted by a Bio-Oss Graft?
A prospective study examining bilateral 3rd molar extraction, by a split mouth protocol the investigators augment unilaterally and compare periodontal parameters in between.
- Trial name
- NCT02753439
- Testing
- Geistlich Bio Oss
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Hemodynamics, Pain
Hemodynamic Effects of Different Vasoconstrictors in Mandibular Exodontia
Title of Study: The Effect of Different Vasoconstrictive Agents on Hemodynamics Among Patients Undergoing Simple Mandibular Exodontia: A Triple-Blind Randomized Controlled Trial Location: King Abdulaziz University Dental Hospital…
- Conditions
- Hemodynamics, Pain, ASA I-II Requiring Simple Dental Extraction of a Mandibular Tooth
- Trial name
- NCT07013071
- Testing
- 2% Mepivacaine with 1:100,000 epinephrine, 2% Mepivacaine with 1:55,000 Epinephrine Bitartrate
- Where
- Saudi Arabia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Tooth, Impacted, Tooth Diseases
Ibuprofen Liquid Capsules 2 x 200 mg Efficacy and PK/PD Study in Surgical Removal of Impacted Third Molars
This is a single centre, three-arm randomised, double-blind, double-dummy, parallel group, single-dose, active and placebo-controlled efficacy and pharmacokinetics/ pharmacodynamics study to evaluate the efficacy and safety of 2…
- Conditions
- Tooth, Impacted, Tooth Diseases, Stomatognathic Diseases
- Trial name
- NCT05484401
- Testing
- Ibuprofen 200Mg Oral Cap, Ibuprofen 200Mg Oral Tablet
- Where
- United States
- Volunteers
- 294 people
- Sponsor
- Reckitt Benckiser Healthcare (UK) Limited
Loss of Teeth Due to Extraction
Evaluation of Healing at Molar Extraction Sites With and Without Ridge Preservation
Following tooth extraction ridge preservation procedure have been suggested to limit bone resorptive dimensional changes to facilitate prospective implant placement.
- Trial name
- NCT02543398
- Testing
- Ridge preservation
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Ridge Preservation
Temporary Anchorage Devices for Ridge Preservation
Alveolar bone is a bony portion surrounding the root of a tooth. The alveolar bone disappears gradually when the tooth is extracted.
- Trial name
- TAD (NCT03205800)
- Testing
- Mini-screw
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Bone Substitutes, Tooth Extraction Status Nos
Adjunctive Use of Polynucleotide and Hyaluronic Acid-based Gel in Alveolar Preservation After Tooth Extraction
Alveolar ridge resorption after tooth extraction is a physiological process that continues throughout the patient's life due to the loss of the periodontal ligament and lack of mechanical stimulation.
- Trial name
- NCT06633211
- Testing
- Alveolar ridge preservation using DBBM + Regenfast + collagen matrix, Alveolar ridge preservation using DBBM + collagen matrix
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Adrià Jorba García
Pain
Evaluation of a TNF-Alpha Modulator for Clinical and Molecular Indicators of Analgesic Effect
This study will evaluate the role of thalidomide, a tumor necrosis factor (TNF)-alpha modulator, on severe inflammation and relief of pain following extraction of wisdom teeth.
- Trial name
- NCT00121563
- Testing
- Thalidomide, Ibuprofen or Diazepam
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Periodontitis, Type 2 Diabetes Mellitus
FM-SRP and Tooth Extraction Improve Type 2 Diabetes Mellitus in Periodontitis
This intervention study is designed to evaluate the effects of non-surgical procedure in addition to surgical procedure on systemic inflammation and glycemic control in with type 2 diabetes mellitus patients with periodontitis in…
- Trial name
- NCT02874963
- Testing
- Surgical Periodontal Treatment, Non Surgical Periodontal Treatment includes scaling root planing with UDS-J Ultrasonic Scaler., Non Surgical Periodontal Treatment includes post operative mouth wash with Listerine® (ethanol 21.6%, methyl salicylate 0.06%, menthol 0.042%, thymol 0.064% and eucalyptol 0.092%)
- Where
- Kosovo
- Volunteers
- 160 people
- Sponsor
- University Clinical Centre of Kosova
Class II Div 1 Malocclusion
Root Resorption in Class II Div 1 Malocclusion in Upper 1st Premolar Extraction vs Distalization
Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable.
- Trial name
- NCT05639725
- Testing
- maxillary Ist premolar extraction, SURGICAL
- Where
- India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Tooth Extraction
Tranexamic Acid To Reduce Bleeding in Patients Treated With New Oral Anticoagulants Undergoing Dental Extraction
In patients treated with direct oral anticoagulants, bleeding events during or after tooth extraction can lead to unscheduled interruption of the antithrombotic treatment and a potential increased risk of thrombo-embolic events.
- Trial name
- EXTRACT-NOAC (NCT03413891)
- Testing
- Tranexamic Acid
- Where
- Belgium
- Volunteers
- 222 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Periodontitis, Gingivitis
Intraoral Scanners as Periodontal and Dental Pathologies Diagnosis Tools
Periodontal diseases and dental pathologies are highly prevalent oral diseases. Thirty-three to fifty percent of adult population presented at least one untreated caries and more than 50% of French population are affected by…
- Conditions
- Periodontitis, Gingivitis, Dental Caries, Diagnosis
- Trial name
- Odonto3D (NCT06006429)
- Testing
- Numerical dental impression by intraoral scanner
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- CHU de Reims