Clinical trials: Extraction, Tooth
Dental Pain
Dental Pain Study of Analgesics in Patients Undergoing Molar Removal
Accessing the efficacy and safety of pregabalin when used alone and in combo with acetaminophen in a dental pain model. To test whether pre-operative dose of pregabalin increases the time to significant post-operative pain (NRS ≥…
- Trial name
- NVK009-0001 (NCT03652818)
- Testing
- Pre-Op pregabalin, Post-Op pregabalin
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Nevakar, Inc.
Pain, Postoperative, Post Operative Swelling
Effect Of Autologous Platelet Rich Fibrin On Post-Operative Complications And Healing Following The Extraction
As post-operative pain, infection inflammation and infections are the main complications after the surgical extraction of the lower third molar the aim of this study is to compare the healing effects of PRF administered…
- Conditions
- Pain, Postoperative, Post Operative Swelling, Trismus, Soft Tissue Healing
- Trial name
- PRF (NCT06609967)
- Testing
- application of PRF, application of conventional surgicel
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Alveolar Process
Evaluation of a Synthetic Bone Substitute for Ridge Preservation
Fifteen patients were selected, each presenting at least two jaw front teeth indicated for extraction: in the Test Group (TG), post-extraction sockets was filled by synthetic bone substitute ReproBone, and in the Control Group…
- Trial name
- NCT02894528
- Testing
- BioMend and ReproBone, BioMend without ReproBone
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Alveolar Bone Loss
Treatment of Alveolar Bone Defects Using Aastrom Biosciences Autologous Tissue Repair Cell Therapy
The purpose of this research is to determine if a subject's own bone marrow tissue can help regenerate bone in the area of his/her jaw where a tooth has been removed using Tissue Repair Cell (TRC) Therapy.
- Trial name
- NCT00755911
- Testing
- Tissue Repair Cells (TRC), Control
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Overcoming the Failure of Anesthesia in the Mandibular Teeth
How Successful is Supplemental Intraseptal Anaesthesia in Patients With Mandibular Teeth Extraction or Irreversible Pulpitis
Introduction: Local anesthetic failure is an unavoidable aspect of dental practice. A number of factors contribute to this, which may be related to either the patient or the operator.
- Trial name
- NCT03880409
- Testing
- 2% lidocaine with 1:000,000 epinephrine, 4% articaine with 1:000,000 epinephrine
- Where
- Saudi Arabia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Taibah University
Missing Teeth
Bone-Implant Contact Surface Influence on Dental Implant Stability
This study aims to evaluate the changes in the stability and bone-implant contact surface of implants of the same macro-design placed with particle grafting in the fresh extraction socket, without grafting, and placed in healed…
- Trial name
- NCT06178796
- Testing
- Dental implant
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Marmara University
Third Molar Extraction
Postoperative Analgesia Following Wisdom Teeth Removal: Ropivacaine Versus Placebo
The main objective of this study is to demonstrate the superiority of local analgesia with ropivacaine versus placebo on postoperative pain during the first 24 hours following bilateral surgery of all four third molars under…
- Trial name
- RopiMol (NCT01541059)
- Testing
- Ropivacaine injection
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Third Molar Surgery
Is Therapeutic Elastic Bandage As Effective As Corticosteroids Following Third Molar Surgery?
In this study; Among the patients randomized because of severe postoperative sequelae expected as a result of radiological and clinical examinations; nonsteroid antiinflammatory drug prescribed group compared with preoperative…
- Trial name
- NCT04200885
- Testing
- Dexketoprofen Trometamol, Dexamethasone 21-Phosphate, Therapeutic Elastic Bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Caries, Dental
Management of Occlusal Dentinal Caries in Deciduous Molars
This study evaluated and compared the efficacy of no caries removal and sealing with a well-adapted and crimped stainless steel crown verses selective caries removal upto soft dentin and upto firm dentin in healing and/or…
- Trial name
- MOD (NCT03552835)
- Testing
- no caries removal, partial caries removal upto soft dentin, partial caries removal upto firm dentin
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sneha D. Suwarnkar
Dental Extraction
Human Placenta Extract Use in Socket Preservation
This split-mouth pilot study evaluates the effectiveness of flowable decellularized Human Placental Connective Tissue Matrix (HPCTM) in alveolar ridge preservation following tooth extraction.
- Trial name
- NCT06915675
- Testing
- Placental Extract, Allograft
- Where
- Lebanon
- Volunteers
- 10 people
- Sponsor
- Saint-Joseph University
Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients
Comparison of Plaque Removal Efficacy of Different Toothbrushes in Clear Aligner Patients
This study aims to compare the effectiveness of manual and powered toothbrushes in removing dental plaque in patients undergoing clear aligner orthodontic treatment.
- Conditions
- Dental Plaque Accumulation, Oral Hygiene in Orthodontic Patients, Clear Aligner Therapy
- Trial name
- NCT07383636
- Testing
- Manual Toothbrush, Powered Toothbrush
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Mersin University
Dental Pain
Phase 2 Study of Indomethacin Capsules to Treat Dental Pain
The purpose of this study is to determine whether Indomethacin Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00964431
- Testing
- Celecoxib 400 mg, Indomethacin Test (lower dose), Indomethacin Test (upper dose)
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Impacted Mandibular Third Molar Extraction, Post Operative Complications
A Comparison of Recovery After Impacted Wisdom Tooth Removal
Justification of the Study There is a high prevalence of impacted third molars, often accompanied by a range of postoperative complications.
- Trial name
- CESE-3M (NCT07304882)
- Testing
- serratiopeptidase, Escin, Conventional drugs
- Where
- Yemen
- Volunteers
- 24 people
- Sponsor
- University of Science and Technology, Yemen
Alveolar Ridge Enlargement
Leukocyte-platelet Rich Fibrin for Alveolar Ridge Preservation
After tooth extraction, there is a subsequent bone loss as a part of the natural healing of the tissue. Up to 50% of bone loss occurs during the first three months after extraction, jeopardizing a possible implant treatment.
- Trial name
- L-PRF (NCT05572242)
- Testing
- Premolar extraction and socked preservation with L-PRF, Premolar extraction and socked preservation with Xenogenic bone and collagen membrane.
- Where
- Chile
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile
Hypomineralization of Enamel, Dental Fear
Analysis of Treatment Outcomes in Patients Affected by Molar-Incisor Hypomineralization (MIH)
The aim is to long-term evaluate extraction or restoration therapy, of first permanent molars with extensive treatment needs as a result of severe MIH in a national multicenter study concerning dental fear and anxiety, oral…
- Conditions
- Hypomineralization of Enamel, Dental Fear, Quality of Life
- Trial name
- GuREx-MIH (NCT06228989)
- Testing
- Restorative therapy, Extraction therapy
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Immediate Dental Implant, Implant Osseointegration
Clinical and Radiographic Evaluation of Topical Vitamin D on Immediate Dental Implants
This study evaluates the clinical and radiographic outcomes of topical vitamin D application on immediate dental implants in patients undergoing single-rooted tooth extraction in the anterior mandibular region.
- Conditions
- Immediate Dental Implant, Implant Osseointegration, Vitamin D, Tooth Extraction
- Trial name
- NCT06806423
- Testing
- Immediate Dental Implant Placement without Adjunctive Treatments, Immediate Dental Implant Placement with Topical Vitamin D Gel Application
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Alveolar Bone Loss
Alveolar Ridge Preservation Techniques After Tooth Extraction
The aim of the present randomized controlled trial (RCT) was to evaluate the efficacy of different alveolar ridge preservation (ARP) techniques on hard tissue dimensional alterations after tooth extraction, based on clinical…
- Trial name
- NCT04934813
- Testing
- Alveolar ridge preservation
- Where
- Greece
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Adult Patients Scheduled for 3rd Molar Teeth Extractions
Comparison of Two Different Doses of Paracetamol for Post-Operative Pain Relief
Paracetamol is commonly used to reduce pain after operations. Recently anaesthetists have been using bigger doses of paracetamol because it has been suggested that bigger doses will work better.
- Trial name
- NCT00286650
- Testing
- 3rd molar teeth extraction
- Where
- New Zealand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Otago
Dental Diseases
A Clinical Trial to Evaluate the Safety and Effectiveness of MatrixOssTM Bone Graft
The objective of this clinical trial is to evaluate the efficacy and safety of MatrixOssTM Bone Graft in bone defect repair caused by tooth extraction.
- Trial name
- NCT05371535
- Testing
- MatrixOssTM Bone Graft plus Bio-Gide membrane
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Collagen Matrix
Pain
The Effectiveness of Buccal Infiltration Only Using Articaine for Extraction of Mandibular Molar
The goal of this clinical trial, is to test out the efficacy of using Articaine only as a local anesthesia as buccal infiltration to extract lower molar teeth.
- Trial name
- NCT06161714
- Testing
- Articaine 4%/Epi 1:100000 Inj Cart 1.7Ml, Lidocaine 2%/Epi 1:100000 Inj Cart 1.7Ml
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University