Clinical trials: Extraction, Tooth
Anesthesia, Tooth Extraction
Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial Surgery
The purpose of this pilot study was to compare two commonly employed intravenous drug combinations; I) nitrous oxide, midazolam, fentanyl, and ketamine and II) the same combination with substitution of propofol for ketamine, for…
- Trial name
- NCT06867068
- Testing
- Midazolam Hydrochloride, Fentanyl, Ketamine
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Jaw, Edentulous, Partially
Study of Bone Preservation When OsseoSpeed™ Implants Are Placed Immediately Following Tooth Extraction
The purpose of this study is to evaluate the clinical performance of implants placed in individuals who are about to loose one or more of their upper teeth.
- Trial name
- NCT00711282
- Testing
- OsseoSpeed™
- Where
- 3 sites in Italy, Spain and 1 more
- Volunteers
- 104 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Gingivitis, Dental Plaque
A Clinical Study Investigating the Effects of a Dentifrice Containing 67% Sodium Bicarbonate When Used Twice Daily for 12 Weeks on Gingivitis Treatment and Plaque Removal
The main goal of this study is to evaluate and compare the efficacy of an on-market dentifrice containing 67 percent (%) sodium bicarbonate and 0.31% sodium fluoride to a reference regular fluoride dentifrice on treating gingival…
- Trial name
- NCT05654662
- Testing
- Corsodyl Original Dentifrice, Colgate Cavity Protection Dentifrice
- Where
- United Kingdom
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- HALEON
Inferior Alveolar Nerve Injuries
Traditional vs Orthodontic Extraction of Impacted Teeth Related to the Inferior Alveolar Nerve
The aim of this clinical study was to compare the effects of traditional and orthodontic extraction methods on postoperative nerve damage in impacted third molars associated with the inferior alveolar nerve.
- Trial name
- NCT06270784
- Testing
- Traditional Extraction, Orthodontic Extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Marmara University
Caries, Dental
Management of Occlusal Dentinal Caries in Deciduous Molars
This study evaluated and compared the efficacy of no caries removal and sealing with a well-adapted and crimped stainless steel crown verses selective caries removal upto soft dentin and upto firm dentin in healing and/or…
- Trial name
- MOD (NCT03552835)
- Testing
- no caries removal, partial caries removal upto soft dentin, partial caries removal upto firm dentin
- Where
- India
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sneha D. Suwarnkar
Deep Caries
Comparing Two Indirect Pulp Capping Agents for Permanent Teeth
Aim of the study: To evaluate clinical and radiographic success rates of silver diamine fluoride versus mineral trioxide aggregate as indirect pulp capping agents in deeply carious young first permanent molars.
- Trial name
- NCT05425368
- Testing
- Silver diamine fluoride, Mineral trioxide aggregate
- Volunteers
- 30 people
- Sponsor
- Cairo University
Tooth Extraction
Tranexamic Acid To Reduce Bleeding in Patients Treated With New Oral Anticoagulants Undergoing Dental Extraction
In patients treated with direct oral anticoagulants, bleeding events during or after tooth extraction can lead to unscheduled interruption of the antithrombotic treatment and a potential increased risk of thrombo-embolic events.
- Trial name
- EXTRACT-NOAC (NCT03413891)
- Testing
- Tranexamic Acid
- Where
- Belgium
- Volunteers
- 222 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dental Pain
Methodological Validation of Ibuprofen Verses Placebo for Post Operative Pain After Third Molar Extraction Surgery
This is a single center placebo controlled, prospective, randomized study on healthy adults undergoing third molar surgery.
- Trial name
- NCT02096926
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Lotus Clinical Research, LLC
Alveolar Bone Loss, Tooth Loss
Changes of Soft and Hard Tissues After Alveolar Ridge Preservation: Freeze-dried Bone Allograft vs. L-PRF Clot
A Clinical Trial to study the effectiveness between two, tooth socket grafting materials namely, Freeze Dried Bone Allograft (human derived bone particles) and Leukocytic-Platelet Rich Fibrin (the patient's own centrifuged…
- Trial name
- NCT03331185
- Testing
- Freeze Dried Bone Allograft, L-PRF clot
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Alveolar Bone Grafting, Bone Healing
Determinants of Bone Dimensional Changes After Extraction and Alveolar Ridge Preservation
The main purpose of the study is to measure and localize immediate post extraction changes i.e. socket expansion versus no width change along the socket wall and identify whether the immediate post-extraction ridge width…
- Conditions
- Alveolar Bone Grafting, Bone Healing, Tooth Extraction Site Healing, Wound Healing
- Trial name
- NCT06624982
- Testing
- observational study
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Marquette University
Reversible Pulpitis, Pulpitis
Antibacterial Effect and Clinical Performance of Chitosan Modified Glass Ionomer
The study is a randomized clinical trial that assesses the clinical success and the antibacterial effect on carious dentine of glass ionomer when modified with Chitosan and/or Titanium dioxide nano particles vs the control group…
- Conditions
- Reversible Pulpitis, Pulpitis, Caries,Dental, Caries Class I
- Trial name
- NCT04365270
- Testing
- Glass Ionomer, Chitosan Low Molecular Weight (20-200 Mpa.S), Chlorhexidine Diacetate
- Where
- Egypt
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tooth Loss
An RCT Comparing Xenograft and Allograft for Ridge Preservation
To compare the effectiveness of demineralized freeze-dried bone allograft + cross-linked collagen membrane with xenograft + non-cross-linked collagen membrane for posterior extraction socket ridge preservation.
- Trial name
- NCT02330523
- Testing
- allograft + x-link collagen membrane, xenograft + non-x-link collagen
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- McGuire Institute
TOOTH EXTRACTION, IMMEDIATE IMPLANT
Autogenous Dentin Derived Barrier Membrane Versus Collagen Membrane
Autogenous Dentin Derived Barrier Membrane versus Collagen Membrane
- Trial name
- DDBM dental (NCT06615362)
- Testing
- preparation of dentin membrane from hopeless tooth for Guided Bone Regeneration in Immediate Implant, Collagen Membrane for Guided Bone Regeneration in Immediate Implant
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Periodontal Disease
Pediatric Study to Access Pharmacokinetics and Safety of Oraqix Gel
To establish Oraqix is safe when used on adolescent volunteers.
- Trial name
- NCT01591616
- Testing
- lidocaine and prilocaine
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Dentsply International
Pain, Extraction, Tooth
Comparison of Pain Perception in A Group of Pediatric Patients Undergoing Maxillary Primary Molar Extraction Using A Novel Anesthetic Device Versus Traditional Infiltration
This study aims to compare the pain felt by children during tooth extraction using two different techniques for giving local anesthesia.
- Trial name
- SO5PED (NCT07124052)
- Testing
- SleeperOne 5, (Conventional Infiltration Anesthesia)
- Volunteers
- 2 people
- Sponsor
- Aya Hesham ElSayed Mohamed ElTanahy
Bone Resorption After Tooth Extraction
3D Printed Scaffold Device for Ridge Preservation After Tooth Extraction
Following tooth extraction, the socket heals naturally with bone in 1 to 2 months. This healing process occurs with substantial reduction of the original height and width of the alveolar ridge.
- Trial name
- NCT03735199
- Testing
- PCL-TCP scaffold, Geistlich Bio-Gide collagen membrane
- Where
- Singapore
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Dental Centre, Singapore
Tooth Extraction, Immediate Dental Implant Placement
IMMEDIATE IMPLANTS: GRAFT VS NO GRAFT
This prospective, randomized, controlled, split-mouth clinical trial aims to evaluate the effect of bone grafting on mandibular bone microstructure following immediate implant placement using fractal analysis of panoramic…
- Conditions
- Tooth Extraction, Immediate Dental Implant Placement, Alveolar Bone Healing After Dental Extraction
- Trial name
- NCT07761195
- Testing
- BONE GRAFTING, NO BONE GRAFT
- Volunteers
- 40 people
- Sponsor
- sema kaya
Dental Implants
Study on Immediate Loading of Immediately Placed Single Implants.
The purpose of this study is to evaluate survival and success rates of dental implants placed with immediate loading protocol in extraction sockets. All patients were monitored for 1 year after implants placement.
- Trial name
- NCT01107600
- Testing
- Immediate implant and socket preservation
- Where
- 2 sites in Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital San Pietro Fatebenefratelli
Diabetes, Anesthesia, Local
Healing Process and Blood Sugar Level Following Local Anesthetic Infiltration With and Without Vasoconstrictor
Evaluating the healing of the extraction socket and the glycemic levels before, and after injection of local anesthesia with and without vasoconstrictor in diabetic patients
- Trial name
- NCT05875519
- Testing
- Local anaesthesia with vasocontrictor (Mepivacaine hydrochloride 20 mg (2%) + Levonordefrin hydrochloride 0.06 mg)
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Anxiety Disease
Comparative Evaluation of Three Anxiety Control Protocols in Third Molar Extraction
The surgery for the extraction of the third molars is a procedure in Dentistry that generates a large picture of anxiety in the patient. One of the ways to try to soften this picture, are the professionals to use sedation.
- Trial name
- NCT03165500
- Testing
- Diazepam, Midazolam, Nitrous Oxide + Oxygen Gas
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual Paulista Júlio de Mesquita Filho