Clinical trials: Extraction, Tooth
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Alveolar Bone Resorption
Alveolar Ridge Preservation Following Tooth Extraction Using Advanced Platelet Rich Fibrin (A-PRF) Versus Platelet Rich Fibrin (PRF)
the aim of this study is clinically and radiographically evaluate the use of advance platelet rich fibrin (A-PRF) versus platelet rich fibrin (PRF) in preservation of alveolar ridge following tooth extraction
- Trial name
- NCT04434703
- Testing
- Platelet rich fibrin (PRF), Advanced platelet rich fibrin (A-PRF), blood clot
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Anxiety, Hemodynamic
Anxiety and Hemodynamic Changes in Third Molar Extraction After Patient Education
This randomized clinical trial investigates the effect of different preoperative patient information strategies on anxiety levels and hemodynamic responses during third molar extraction.
- Conditions
- Dental Anxiety, Hemodynamic, Molar, Third, Tooth Extraction
- Trial name
- NCT07018115
- Testing
- Basic Preoperative Information, Detailed Verbal Preoperative Information, Visual Preoperative Information (2D Animation)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Ummugulsum Coskun
Extracting Own Teeth, Bone Substitutes
Evaluation of Bone Preservation After Molar Extraction Using Photobiomodulation Combined With Biomaterial Grafting
Tooth loss is a global public health problem and is the main cause of occlusal and oral bone deformities. The tooth with the greatest tooth loss can be identified as first molars.
- Trial name
- NCT06164626
- Testing
- Extraction, low level laser therapy, Plenum® OSShp and Plenum® Guide
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Local Anesthesia
Effects of Articaine Computer-controlled and Conventional Delivery for Anterior and Middle Superior Alveolar Nerve Block for Tooth Extraction
The purpose of this study was to investigate and compare pulpal anesthesia and cardiovascular parameters obtained with 0.6 ml of 4% articaine with epinephrine (1:100.000) for anterior and middle superior alveolar nerve (AMSA)…
- Trial name
- NCT03225326
- Testing
- Computer controlled 4% articaine delivery by Anaeject, Conventional 4% articaine delivery by carpule syringe
- Where
- Serbia
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Belgrade
Dental Pain
Evaluation of the Efficacy and Safety of Diclofenac HPBCD 25, 50 mg/ml in the Treatment of Post-surgical Pain Following Dental Surgery
The present study is proposed to evaluate the efficacy and safety of single doses of Diclofenac HPBCD subcutaneous (s.c.) (25 mg/1 ml and 50 mg/1 ml) in the treatment of acute moderate-to-severe pain after dental impaction…
- Trial name
- NCT00942448
- Testing
- Diclofenac HPBCD
- Where
- 6 sites in Poland, United Kingdom
- Volunteers
- 306 people
- Sponsor
- IBSA Institut Biochimique SA
Multiple Adjacent Teeth, Bone Remodelling
Dimensional Alterations of the Edentulous Ridge Following Removal of Multiple Adjacent Teeth
The objective of the present study is to evaluate if loss of multiple adjacent teeth will cause proportionally greater tissue diminution than the loss of single teeth the possibility of counteracting unfavourable ridge modeling…
- Trial name
- NCT02401789
- Testing
- Implants (OsseospeedTM,EV Astra Tech System, DentsplyTM, Mölndal)
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Institute Franci
Impacted Third Molar Tooth
Investigation of the Effects of H-PRF on the Period After Impacted Third Molar Tooth Extraction
After wisdom teeth are extracted, the patient may have some complaints in the post-operative period. Pain, swelling and edema are some of them.
- Trial name
- NCT06244797
- Testing
- L-PRF and H-PRF, Impacted Tooth Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- esengul sen
Impacted Third Molar Tooth
Clinical Efficacy of a New Piezoelectric Technique for Wisdom Teeth Extraction
the aim of this randomized controlled clinical study is to evaluate the efficacy of a new piezoelectric technique for wisdom teeth extraction without using manual tools versus the conventional one.Patients referred to the…
- Trial name
- NCT03619460
- Testing
- piezoelectric extraction, conventional extraction
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Bolzano
Dental Pain
Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction
This is a Phase 3, randomized, double-blind, placebo-controlled study in subjects scheduled to undergo elective bilateral third molar extraction under local anesthesia.
- Trial name
- NCT02517905
- Testing
- Bupivacaine liposome
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Dental Pain
Study of Acetaminophen (ACE) in Post-operative Dental Pain
This is a dental pain study evaluating the efficacy and safety of a single dose of test acetaminophen (ACE) (1000 mg) compared to commercial acetaminophen (1000 mg), ibuprofen (IBU) (400 mg), and placebo over a 6 hour period.
- Trial name
- NCT02320708
- Testing
- Acetaminophen (ACE) (1000 mg), Commercial ACE (1000 mg), Commercial Ibuprofen (IBU) (400 mg)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.
Socket Preservation
Study on Platelet-Rich Fibrin for Preserving Jawbone After Tooth Extraction Using CBCT Imaging in Adults
The goal of this clinical trial is to learn if platelet-rich fibrin (PRF), a substance made from a person's own blood, helps preserve the bone in the jaw after tooth extraction in adults.
- Trial name
- NCT07022860
- Testing
- Platelet-rich fibrin (PRF)
- Where
- Iran
- Volunteers
- 12 people
- Sponsor
- Zahedan University of Medical Sciences
Post-surgical Oral Wounds, Oral Cavity Surgery
Evaluation of the Performance and Safety of a Linear Hyaluronic Acid-Based Medical Device in the Treatment of Surgical Wounds in the Oral Cavity.
The PR-DENT study is an interventional, single-center, controlled clinical investigation aimed at evaluating the clinical performance and safety of a Class III medical device based on linear hyaluronic acid for the treatment of…
- Conditions
- Post-surgical Oral Wounds, Oral Cavity Surgery, Wound Healing/Regeneration, Dental Extraction Sites
- Trial name
- PR-DENT (NCT07421934)
- Testing
- Intervention: Linear Hyaluronic Acid (Gumblast), Control: Standard Surgical Procedure
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- The Wave Innovation Group s.r.l.
Tooth Loss, Alveolar Ridge Resorption After Extraction
BMP Effect on Implant Stability and Marginal Bone Level After Immediate Placement
This randomized controlled clinical trial aims to evaluate the effect of recombinant human Bone Morphogenetic Protein-2 (rhBMP-2) on the stability and marginal bone level of dental implants following immediate placement.
- Conditions
- Tooth Loss, Alveolar Ridge Resorption After Extraction, Tooth Extraction
- Trial name
- NCT07240493
- Testing
- rhBMP-2 placement, conventional immediate implant
- Where
- Iraq
- Volunteers
- 24 people
- Sponsor
- Aya Adil Saeed
Tooth Loss
The Use of Dental Pulp Tissue as an Autogenous Graft for Ridge Augmentation
The purpose of this study is to examine and compare the effects of autogenous dental pulp tissue on bone formation in the extraction sockets as compared to commonly used particulate bone graft.
- Trial name
- NCT03943849
- Testing
- Particulate bone graft, Autogenous dental pulp tissue, Resorbable collagen membrane
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Tooth Loss
A Comparison of Two Socket Sealing Collagen Matrices for Extraction Socket Management
A prospective RCT of intact extractions with delayed implant placement comparing extraction socket management effectiveness and office economics of two collagen matrices.
- Trial name
- NCT03003819
- Testing
- Control Collagen Wound Dressing, Test Collagen Matrix
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- McGuire Institute
Ridge Preservation
Temporary Anchorage Devices for Ridge Preservation
Alveolar bone is a bony portion surrounding the root of a tooth. The alveolar bone disappears gradually when the tooth is extracted.
- Trial name
- TAD (NCT03205800)
- Testing
- Mini-screw
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Non-restorable Teeth, Intraoral Surgical Incisions
Efficacy of Using Knotless Barbed Suture vs N-Butyl Cyanoacrylate Glue Tissue Adhesive for Closure of Intraoral Surgical Incisions
This clinical study aims to compare the efficacy of knotless barbed sutures versus N-butyl cyanoacrylate glue tissue adhesive for the closure of intra-oral surgical incisions, with traditional PGA vicryl sutures as a control…
- Conditions
- Non-restorable Teeth, Intraoral Surgical Incisions, Wound Closure, Surgical Tooth Extraction
- Trial name
- KBA vs CA (NCT07491276)
- Testing
- PDO Knotless Barbed Suture, N-Butyl Cyanoacrylate Glue (PERIACRYL), 3/0 Resorbable PGA Suture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Future University in Egypt
Root Canal Infection
Radicular Dentin Remaining, Risk of Perforation and Canal Transportation in Manual Versus Rotary Instrumentation in Primary Molars
Background: Root canal preparation techniques using manual instruments have found to be time-consuming and may lead to iatrogenic errors such as ledging, zipping, canal transportation, and apical blockage.
- Trial name
- NCT04793308
- Testing
- Endodontic files
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Glycemic Level
Effect of Adrenaline (1:80,000) Containing Local Anesthesia on Glycemic Level of Diabetic and Healthy Individuals Undergoing Tooth Extraction
Dental extraction is one of the most frequently performed surgical interventions worldwide, and local anaesthesia remains its pharmacological foundation.The addition of adrenaline (epinephrine) 1:80 000 to lignocaine 2 % is…
- Trial name
- NCT07633106
- Testing
- Local anesthesia with 1:80000 adrenaline
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences