Clinical trials: Extraction of Third Molar Teeth
Class II Malocclusion
Effect of Maxillary Third Molar Extraction vs. Non-extraction on Distalization of First Molars in a Group of Adolescent Patients
There is a scarcity in literature regarding the influence of maxillary third molar on distalization . This study aimed to compare the influence of unerupted maxillary third molars and their extraction on the bilateral…
- Trial name
- NCT05647720
- Testing
- Distalization combined with upper third molars extraction, Distalization without upper third molars extraction
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Tooth, Impacted, Dental Anxiety
Evaluation of the Effectiveness of Aromatherapy on Anxiety, Vital Signs, and Postoperative Complications in Lower Impacted Wisdom Tooth Surgery
Dental anxiety is considered to be one of the fears and concerns associated with dental treatment. Lavender has a relaxing and anxiolytic aroma.
- Trial name
- NCT06101446
- Testing
- Lavander Aromatherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Pain, Edema
Leukocyte- and Platelet Rich Fibrin (L-PRF) Application in Impacted Mandibular Third Molar Removal Surgery
The purpose of this study was to evaluate the influence of leukocyte- and platelet-rich fibrin (L-PRF) on impacted mandibular third molar (IMTM) extraction wound healing, patient postoperative discomfort, and incidence of…
- Conditions
- Pain, Edema, Wound Heal
- Trial name
- NCT03357484
- Testing
- Leukocyte- and platelet rich fibrin, Blood clot
- Where
- Lithuania
- Volunteers
- 30 people
- Sponsor
- Lithuanian University of Health Sciences
To Control Pain After Third Molar Surgery
Efficacy of Preoperative Administration of Paracetamol-codeine on Pain Following Impacted Mandibular Third Molar Surgery
Objectives: The aim of this study was to determine the effectiveness of preoperative administration of single-dose of paracetamol-codeine, in the relieving of acute post-operative pain after the surgical removal of an impacted…
- Trial name
- NCT03049878
- Testing
- Paracetamol Codeine
- Volunteers
- 32 people
- Sponsor
- University of Roma La Sapienza
Impacted Third Molar Tooth
Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar
Background: One of the most frequent surgical operations in dentistry is the surgical extraction of the impacted mandibular third molar, which is accompanied by a sequelae of swelling, trismus, and pain.
- Trial name
- NCT06144983
- Testing
- Alvogyl, Chlorhexidine Gluconate
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Wisdom Tooth Removal, Antibiotic Prophylaxis
Comparison of Amoxicillin, Clindamycin and Azithromycin Single Doses Antibiotic Prophylaxis in Patient Undergoing Lower Third Molar Extraction
The goal of this clinical trial is to learn which drug amongst Amoxicillin, Clindamycin and Azithromycin single dose works better in reducing post-surgical complications in Participants getting lower wisdom teeth pulled.
- Conditions
- Wisdom Tooth Removal, Antibiotic Prophylaxis, Single Dose
- Trial name
- NCT07894016
- Testing
- Amoxicillin 2g, Clindamycin 600 mg, Azithromycin 500mg
- Volunteers
- 105 people
- Sponsor
- Dow University of Health Sciences
Toothache
SB-705498 Dental Pain Study After Tooth Extraction
This clinical trial is a multi centre, randomised, single-blind, parallel group, placebo-controlled, single oral dose study with a positive control arm.
- Trial name
- NCT00281684
- Testing
- SB705498 400 mg, SB705498 1000 mg, Co-Codamol
- Where
- 5 sites in Italy, South Korea and 1 more
- Volunteers
- 145 people
- Sponsor
- GlaxoSmithKline
Dental Pain
Study of Buprenorphine HCl Buccal Film in the Treatment of Dental Pain
The purpose of this study is to assess the activity of buprenorphine hydrochloride (HCl) buccal film in the treatment of dental pain.
- Trial name
- NCT00941304
- Testing
- Oxycodone, Buprenorphine
- Where
- 3 sites in United States
- Volunteers
- 153 people
- Sponsor
- BioDelivery Sciences International
Wisdom Teeth, Oral Surgery
Microbial Growth in the Suture Thread, After Application of Different Antiseptic Gels in Mandibular Third Molars Extraction
This is a randomized clinical trial in which investigators will compare the antimicrobial effect and inducer of cicatrization as well as the degree of postoperative pain in patients who are extracted the lower third molars.
- Conditions
- Wisdom Teeth, Oral Surgery, Third Molar Surgery, Bioadhesive Gel
- Trial name
- NCT03188289
- Testing
- Clorhexidine gel, Clorhexidine-Chitosan gel, Hyaluronic Acid gel
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
PRF
The Efficacy of A-PRF+ on Postoperative Outcomes Following Surgical Removal of Impacted Mandibular Third Molars (A-PRF+: Advanced Platelet Rich Fibrin)
Objectives: This study aims to evaluate the effects of A-PRF+ on postoperative pain, swelling, and trismus after surgical removal of impacted mandibular third molars.
- Trial name
- A-PRF+ (NCT05824793)
- Testing
- A-PRF+
- Where
- Vietnam
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
The Application of Hyaluronic Acid on Teeth Bone Healing. Hyaluronic Acid Which is Widely Used in Medicine for Joint, Eye Care, Wound Healing
Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets
Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars.
- Trial name
- NCT07318298
- Testing
- Surgical extraction of wisdom teeth, bone biobsy
- Where
- Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Impacted Third Molar Tooth
Computer Guided Versus Conventional Surgical Removal of Deeply Impacted Mandibular Third Molar With Preservation of External Oblique Ridge
in patent have deeply impacted lower third molar ,dose computer guided enhance surgical outcome versus conventional surgical remove of wisdom teeth
- Trial name
- NCT03447067
- Testing
- computer guided surgical, Conventional surgery, CBCT
- Volunteers
- 18 people
- Sponsor
- Alaadden Mahmoud Abu Al Enein
Dental Anxiety, Sedation Complication
Remimazolam in the Extraction of Impacted Wisdom Teeth
Benzodiazepines, represented by midazolam, are often used for sedation in outpatient surgery in dentistry. However, midazolam has the problems of slow consciousness recovery and long recovery time, which brings trouble to the…
- Conditions
- Dental Anxiety, Sedation Complication, Anterograde Amnesia
- Trial name
- NCT05350085
- Testing
- Remimazolam besylate, Midazolam
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Wisdom Teeth Extraction or Jaw Implant
Levels of Fear, Anxiety and Wound Healing Among Aental Surgery Patients Under Local Versus General Anesthesia
Tooth extraction is one of the most common procedures in dentistry. Surgical extraction of damaged wisdom teeth involves bone resection and injury to the soft tissue.
- Trial name
- NCT06380608
- Testing
- Local anesthesia, General anesthesia
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Zoya Haitov Ben Zikri
Third Molars Extraction
Improvement of Operating Room Efficiency in Bilateral Wisdom Teeth Surgery
This study aims to assess and compare the implementation of this comprehensive program in patients undergoing bilateral third molar extraction on OR and hospital efficiency and patient experience.
- Trial name
- PREPARE (NCT06873152)
- Testing
- Control preoperative program, Advanced preoperative program
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Jessa Hospital
Adult Patients Scheduled for 3rd Molar Teeth Extractions
Comparison of Two Different Doses of Paracetamol for Post-Operative Pain Relief
Paracetamol is commonly used to reduce pain after operations. Recently anaesthetists have been using bigger doses of paracetamol because it has been suggested that bigger doses will work better.
- Trial name
- NCT00286650
- Testing
- 3rd molar teeth extraction
- Where
- New Zealand
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Otago
Impacted Third Molar, Impacted Third Molar Tooth
Prospective Evaluation of Efficacy of Tumescent Steroid Infiltration in Mandibular Third Molar Surgery: a Split Mouth Randomized Study
The aim of this study is to evaluate the efficacy of tumescent solution on post operative sequalae in patients treated for surgical removal of impacted lower third molar. The objectives are Primary Objective 1.
- Conditions
- Impacted Third Molar, Impacted Third Molar Tooth, Third Molar Extraction, Third Molar Extraction Surgery
- Trial name
- NCT07436546
- Testing
- Tumescent Infiltration (dexamethasone, bupivacaine, adrenaline, hyaluronidase, saline), 2% lignocaine with adr (1:2,00,000)
- Where
- India
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Teeth, Impacted
Bupivacaine in the Treatment of Postoperative Pain of Impacted Third Molar Extraction
The third molars are the teeth that are most frequently included and impacted, extraction is one of the most performed treatments by maxillofacial surgeons in their clinical practice.
- Trial name
- NCT03950700
- Testing
- Bupivacaine-epinephrine, Saline Solution
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
Dental Pain and Sensation Disorder, Pain, Postoperative
Efficacy of Preoperative Administration of Gabapentin in 3rd Molar Dental Extraction.
This study is a double-blind, randomized, prospective, placebo-controlled single-center clinical research study in which 600 mg of gabapentin or placebo will be administered 2 hours preoperatively to 49 patients each undergoing…
- Trial name
- NCT04860141
- Testing
- Gabapentin 600mg
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Dental Pain, Sensation Disorders
Meloxicam Versus Ibuprofen for Pain Control After Third Molar Exodontia in Adult Patients
Third molar extraction is a common dental procedure, offently related with pain and swelling. The purpose of this study is to evaluate if Meloxicam has a better effect relieving pain after the extraction than Ibuprofen, one of…
- Trial name
- NCT06704113
- Testing
- meloxicam 7,5mg
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile