Clinical trials: Extremity Injury
Upper Extremity Injury
Infraclavicular Brachial Plexus Block With Bupivacaine Alone or With Both Dexmedetomidine and Dexamethasone
Upper-extremity regional anesthetic techniques, using brachial plexus blockade, have been shown to reduce adverse effects related to opioid administration, improve patient satisfaction, and provide significantly improved…
- Trial name
- NCT06356415
- Testing
- Bupivacaine injection, Bupivacaine+ Dexamethasone+ Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Lower Limb Ischaemia, Aneurysm
Bacterial Growth in Vascular Surgery Wounds
The amount and species of bacteria have been shown to have an effect in wound infections in several fields of surgery (such as gastrointestinal and orthopaedic surgery and the surgery of facial area).
- Trial name
- NCT01505738
- Testing
- bacterial samples
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- North Karelia Central Hospital
Lower Extremity Diabetic Leg Wounds, Lower Extremity Venous Leg Wounds
Clinical Evaluation of the SNaP Wound Care System in Promoting Healing in Chronic Wounds
The purpose of this study is to evaluate a novel topical negative pressure (TNP) wound therapy device called the SNaP® (Smart Negative Pressure) Wound Care System for the treatment of lower extremity diabetic, venous and mixed…
- Conditions
- Lower Extremity Diabetic Leg Wounds, Lower Extremity Venous Leg Wounds, Lower Extremity Mixed Aetiology Leg Wounds
- Trial name
- NCT01417208
- Testing
- SNaP® Wound Care System
- Where
- United Kingdom
- Sponsor
- KCI USA, Inc
Bone Fracture
Enhancement of Bone Regeneration and Healing in the Extremities by the Use of Autologous BonoFill-II
The purpose of this clinical study is to evaluate the safety and the efficacy of BonoFill-II as an autologous bone-regenerating graft in the reconstruction of deficient bone in two clinical indications: 1.
- Trial name
- NCT03024008
- Testing
- BonoFill-II
- Where
- 6 sites in Israel
- Volunteers
- 40 people
- Sponsor
- BonusBio Group Ltd
Lower Limb Amputation Below Knee (Injury)
Influence of Socket Volume on Prosthesis Performance
The purpose of this study is to investigate how residual limb fluid volume, gait, prosthesis use, perceived comfort, and satisfaction with the prosthesis are affected by size of the prosthetic socket.
- Trial name
- CAD (NCT02124915)
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Washington
Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb
Screw Lengths in Radius Volar Plates
Background Fractures of the distal radius are among the most common. Major complications, including irritation and rupture of the extensor tendons, may occur if epiphyseal screws of inappropriate length are used.
- Conditions
- Radius; Fracture, Lower or Distal End, Tendon Injury - Upper Limb, Fracture Fixation, Internal
- Trial name
- PESLDRF (NCT03634865)
- Where
- France
- Volunteers
- 41 people
- Sponsor
- University Hospital, Brest
Prosthesis User, Lower Limb Amputation Below Knee (Injury)
Caesar Foot Take-Home Validation Testing
The rationale for this study is to conduct a take-home clinical trial to evaluate the impact of the bimodal Caesar foot in a real-world environment.
- Trial name
- NCT07075198
- Testing
- Caesar Foot
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Liberating Technologies, Inc.
Critical Lower Limb Ischemia, Critical Limb Ischemia
Evaluation of Carbothera in the Treatment of Foot Ulcers
Foot ulceration usually precedes more serious foot complications such as infection, gangrene or amputation. The risk of developing foot ulcers has been estimated to be higher in individuals with kidney disease.
- Conditions
- Critical Lower Limb Ischemia, Critical Limb Ischemia, Foot Ulcer, Skin Ulceration
- Trial name
- NCT02239419
- Testing
- CO2-Enriched Tap Water (Carbothera), Non-CO2-Enriched Tap Water
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Lower Extremity Injury
Cohort Study of PPP Injections for Athletes With Muscle Injury
The investigators hypothesize that a single injection of platelet-poor plasma (PPP) into an acute muscle injury will significantly improve local muscle regeneration and patient outcomes compared to the standard of care using only…
- Trial name
- NCT07566039
- Testing
- Platelet Poor Plasma (PPP) Injection
- Where
- 3 sites in United States
- Volunteers
- 90 people
- Sponsor
- University of Colorado, Denver
Upper Extremity Injury, Upper Extremity Deformities, Congenital
SoftHand Comparison Study
A trial to compare the performance of the SoftHand Pro (SHP) and Ossur i-Limb in people with transradial limb loss over an 8-week period.
- Conditions
- Upper Extremity Injury, Upper Extremity Deformities, Congenital, Amputation, Traumatic, Amputation, Congenital
- Trial name
- NCT05328934
- Testing
- SoftHand Pro, Ossur i-Limb
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- Mayo Clinic
Peripheral Arterial Disease, Intermittent Claudication
Heat Therapy for Peripheral Arterial Disease (HEATPAD)
Peripheral arterial disease (PAD) is a disabling condition, with symptoms of muscle cramping or pain on exertion, which can substantially reduce quality of life.
- Conditions
- Peripheral Arterial Disease, Intermittent Claudication, Critical Limb Ischemia
- Trial name
- HEATPAD (NCT06186505)
- Testing
- AirGlove
- Volunteers
- healthy volunteers welcome
- Sponsor
- Norfolk and Norwich University Hospitals NHS Foundation Trust
Traumatic Spinal Cord Injuries
Recovery of Upper Limb Function in Persons With Spinal Cord Injury: Lead-In Study
Many individuals with cervical spinal cord injury (SCI) have difficulty using their hands and arms. MyndMove is a non-invasive medical device that uses short, low energy electrical pulses with surface electrodes to cause muscle…
- Trial name
- MyndMove (NCT02799966)
- Testing
- Myndmove
- Where
- 3 sites in Canada
- Volunteers
- 9 people
- Sponsor
- University of British Columbia
Acquired Brain Injury (Including Stroke)
Clinical Investigation to Validate the Safety and Performance of the ABLE Exoskeleton Device for Individuals With Acquired Brain Injury in a Clinical Setting
The primary objective of the study is to validate the safety and clinical performance of the ABLE Exoskeleton device in people with acquired brain injury during a 10-session gait training program in a clinical setting.
- Trial name
- NCT07050875
- Testing
- ABLE Exoskeleton
- Where
- 3 sites in Spain
- Volunteers
- 14 people
- Sponsor
- ABLE Human Motion S.L.
Trauma to the Arm, Shoulder, Elbow, Forearm, or Hand
Ultrasound Visualization Versus Electrical Nerve Stimulation
Hypothesis and Specific Aims: The investigators hypothesize that ultrasound (US) visualization is as effective as nerve stimulation (NS) for identification of peripheral nervous structures and may be associated with less trauma…
- Trial name
- NCT01010412
- Testing
- Ultrasound (Sonosite Titan T-shaped ultrasound probe), Electrical Nerve Stimulation (Stimuplex (B Braun) needle)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Allentown Anesthesia Associates
Lymphedema
Effect Of Complete Decongestive Therapy On Carpal Tunnel Syndrome Post Upper Limb Lymphedema
this study will be conducted to investigate the therapeutic effect of complete decongestive therapy on carpal tunnel syndrome post-upper limb lymphedema.
- Trial name
- CDT (NCT05932381)
- Testing
- Complete decongestive therapy, Medical treatment
- Volunteers
- 60 people
- Sponsor
- Cairo University
Hip Arthropathy, Hip Dysplasia
Mid-Term Natural Course Postoperative of Crowe Type III-IV Hip Dysplasia
Comparison of preoperative and postoperative mid-term course of patients with Crowe Type 3 and Type 4 hip dysplasia.
- Trial name
- NCT05149729
- Testing
- Shortened hip arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Bezmialem Vakif University
Vascular Accident, Brain, Traumatic Brain Injury
Automated Versus Standard Physiotherapy for Upper Limb Rehabilitation in Patients With Acquired Brain Lesions
The Armeo Spring has proven its effectiveness in the rehabilitation of acute stroke patients. It neutralizes limb weight, enabling patients to use residual control in both arm and hand and to follow exercises guided by…
- Trial name
- NCT01398553
- Testing
- Armeo Spring, conventional physiotherapy
- Where
- 2 sites in Italy
- Sponsor
- Krankenhaus Bozen
SCI - Spinal Cord Injury
The Efficacy of Upper Extremity Wearable Robotic Orthosis on Improving Upper Extremity Motor Function and Activities of Daily Living in Persons With Spinal Cord Injury
To evaluate the usefulness of an upper extremity (UE) assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury (iSCI)
- Trial name
- MyoMo in SCI (NCT04855812)
- Testing
- MyoMo, Myo-SB, Control
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Kessler Foundation
Spinal Cord Injury
Bone Strength After Spinal Cord Injury
Background: After a traumatic spinal cord injury, a severe bone loss in the paralyzed extremities is observed. This leads to a osteoporosis which is connected to a high fracture risk.
- Trial name
- NCT01853488
- Testing
- DXA, pQCT
- Where
- Switzerland
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Peripheral Nerve Injury(Ies)
Study of Nerve Repair and Reconstruction Associated With Major Extremity Trauma
This is a multi-center prospective observational study that will capture detailed information about the treatment and long term outcomes of 250 patients with PNI resulting from upper extremity trauma.
- Trial name
- Nerve (NCT02718768)
- Where
- 17 sites in United States
- Volunteers
- 242 people
- Sponsor
- Major Extremity Trauma Research Consortium