Clinical trials: Extremity Injury
Upper Extremity Spasticity, Stroke
Efficacy of Functional Electrical Stimulation (FES) in Persons Receiving Botulinum Neurotoxin for Upper Extremity Spasticity
FES is a form of treatment with a device to aid movement in people who have had damage to their brain or spinal cord. Small electrical impulses are used to excite/stimulate the nerves that supply paralyzed muscles.
- Conditions
- Upper Extremity Spasticity, Stroke, Acquired Brain Injury
- Trial name
- Botox + FES (NCT00462449)
- Testing
- Functional Electrical Stimulation (FES) through the Ness H200
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Pittsburgh
Pain
Safety and Efficacy Study of Fentanyl Buccal Tablet Use in the Emergency Department for Isolated Extremity Injury
The primary purpose of this study is to evaluate fentanyl buccal tablet (FBT) for analgesia in comparison to standard analgesia, to determine if the FBT allows for faster achievement of "significant analgesia"
- Trial name
- FAIRTOP II (NCT01270659)
- Testing
- Fentanyl, Oxycodone/acetaminophen
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Oklahoma
Peripheral Arterial Disease, Intermittent Claudication
A New Heat Therapy Device for Home-based Leg Heating in Patients With Lower-extremity Peripheral Artery Disease
The goal of the proposed pilot study is to evaluate the feasibility of a new leg heat therapy system treatment for patients with lower extremity PAD.
- Trial name
- NCT05335161
- Testing
- Home-based leg heat therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Purdue University
Of Bypass Graft of the Extremities, Peripheral Arterial Disease
Standard Versus PICO Dressings in Lower-Extremity Bypass Patients
The objective of this study is to compare the effectiveness of standard moist dressings and PICO single-use negative pressure dressings in post-operative lower extremity bypass patients.
- Conditions
- Of Bypass Graft of the Extremities, Peripheral Arterial Disease, Vascular Diseases, Cardiovascular Diseases
- Trial name
- PICO-LEB (NCT02492854)
- Testing
- PICO Single-Use Negative Pressure Dressings, Sterile Gauze Dressings
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Boston Medical Center
Leg Spasticity
Dysport® Adult Lower Limb Spasticity Study
The purpose of this research study is to assess the efficacy of Dysport® compared to placebo in improving muscle tone in hemiparetic subjects with lower limb spasticity due to stroke or traumatic brain injury.
- Trial name
- NCT01249404
- Testing
- Botulinum toxin type A
- Where
- 62 sites in United States, Australia and 9 more
- Volunteers
- 388 people
- Sponsor
- Ipsen
Neuralgia
P4 (Pregabalin for Peripheral Posttraumatic Pain)
To evaluate the efficacy of pregabalin compared to placebo in the treatment of posttraumatic peripheral neuropathic pain
- Trial name
- P4 (NCT00292188)
- Testing
- pregabalin
- Where
- 44 sites in Belgium, Canada and 9 more
- Volunteers
- 255 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Acquired Brain Injury
Effects of Combined Spinal Direct Current Stimulation on Upper Limb Recovery in Acquired Brain Injury
This study will compare different polarities of transcutaneous spinal direct current stimulation combined with robotic-assisted arm training (RAT) in adults with acquired brain injury (ABI).
- Trial name
- NCT03100370
- Testing
- tsDCS-Anodal Stimulation, tsDCS-Cathodal Stimulation, Robotic-assisted training of arm and hand functions
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Health Science Center, Houston
Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Cervical Transcutaneous SCS for TBI
The goal of this study is to test the effects of non-invasive electrical stimulation of the spinal cord (called transcutaneous spinal cord stimulation, or tSCS) on arm and hand movement in people with motor impairments after a…
- Trial name
- NCT07147816
- Testing
- Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Roberto de Freitas
Bone Fracture, Radius Fracture
Study on Wood-plastic Composite for Circumferential Casting
The purpose of study is to verify that WOODCAST Circular system performs safely and effectively in its intended use.
- Conditions
- Bone Fracture, Radius Fracture, Ankle Fracture
- Trial name
- WOODCAST (NCT01493167)
- Testing
- limb casting/splinting
- Where
- Finland
- Volunteers
- 97 people
- Sponsor
- Onbone Oy
Upper Extremity Injury, Sport Injury
Throwers Ten Exercises On Upper Extremity Function and Explosive Power in Wheelchair Basketball and Basketball Players
Basketball is a challenging sport that requires participants to demonstrate physical fitness and special athletic skills at high levels.
- Conditions
- Upper Extremity Injury, Sport Injury, Shoulder Pain, Muscle Weakness
- Trial name
- NCT04019990
- Testing
- The effect of throwers ten exercise programme on wheelchair basketball and ambulant basketball players
- Where
- Cyprus
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cervical Spinal Cord Injruy
Improving SCI Rehabilitation Interventions by Retraining the Brain
The Long-term goal of this project is to develop upper limb rehabilitation interventions that can be utilized for cervical Spinal Cord Injury survivors.
- Trial name
- NCT03892746
- Testing
- Active tDCS + task oriented practice
- Where
- 4 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Lower Extremity Wound Infected, Venous Stasis Ulcers
V.A.C. VeraFlo™ Instillation Therapy vs V.A.C. Ulta™ Therapy on Biofilm in Chronically Infected Wounds
This study would like to determine if using negative pressure wound therapy with an instillation of .125% Dakins is more effective than using negative pressure wound therapy alone on biofilm removal, disruption and elimination in…
- Trial name
- NCT02009501
- Testing
- VAC VeraFlo with Dakins Instillation, VAC Ulta Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Wound
An Evaluation of a Collagen Dressing to Treat Chronic, Stalled Lower-extremity Wounds
Patients who meet the inclusion criteria will be provided with fibrillar collagen powder dressing. The powder dressing will be used in accordance with its label.
- Trial name
- NCT03723603
- Testing
- Fibrillar collagen powder dressing
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Medline Industries