Clinical trials: Eye Allergies
Refractive Errors
Comparison of Higher Order Aberrations and Contrast Sensitivity Between Acrysof SN60AT, SN60WF and Restore Intraocular Lenses
This project involves evaluation of post operative contrast sensitivity and wavefront aberration results among patients implanted with standard monofocal lenses (Acrysof SN60AT/SN60WF) and the new presbyopic correcting multifocal…
- Trial name
- NCT00345085
- Testing
- Wavefront and Contrast Sensitivity
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypersensitivity
Non-Pharmaceutical Treatment of Seasonal Allergic Conjunctivitis
Seasonal allergic conjunctivitis (SAC) is an irritating eye condition that affects many people, caused by hypersensitivity to normally harmless substances such as pollen, and often accompanies seasonal hay fever.
- Trial name
- NCT01569191
- Testing
- Artificial Tear Supplement, Cold compress, Anti-allergic Medication
- Where
- United Kingdom
- Volunteers
- 18 people
- Sponsor
- Aston University
Allergic Conjunctivitis
A Six-Week Safety Study of an Investigational Ophthalmic Solution
The purpose of this study was to evaluate the ocular safety of an investigational ophthalmic solution in subjects 2 years of age and older with asymptomatic eyes when administered once daily in both eyes for up to 6 weeks.
- Trial name
- NCT01698814
- Testing
- AL-4943A Ophthalmic Solution, AL-4943A Ophthalmic Solution Vehicle
- Volunteers
- 518 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Allergic Conjunctivitis
The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic Conjunctivitis
A double-blind study to evaluate the role of vitamin D in corneal epithelial barrier function, ocular microbiome, ocular inflammation, and visual acuity of children with allergic conjunctivitis.
- Trial name
- NCT05839938
- Testing
- Vitamin D
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Allergic Conjunctivitis
A Study Of The Safety And Effectiveness Of A New Treatment For Allergic Conjunctivitis
This study will evaluate the safety and efficacy of a new allergy medication
- Trial name
- NCT00375596
- Testing
- Ketotifen/vasoconstrictor
- Sponsor
- Bausch & Lomb Incorporated
Corneal Disease, Hypersensitivity
Hybrid SA RGP Center/S-H Skirt Daily Wear 90 Day Multicenter Study
The purpose of the study is to demonstrate that the SynergEyes SA Hybrid Contact Lens clinical performance is substantially equivalent to that of the SynergEyes A Hybrid Lens when studied: within the corresponding range of lens…
- Trial name
- NCT00804505
- Testing
- SynergEyes Hybrid (petrafocon A hem-larafilcon A) Hybrid Contact Lens, SynergEyes Hybrid (paflufocon D hem-iberfilcon A) Contact Lens
- Where
- 8 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- SynergEyes, Inc.
Allergic Rhinitis Due to Cat Allergy
A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat
The primary objective of the study is to determine the efficacy of REGN1908-1909, as compared to placebo, to reduce allergic rhinitis/conjunctivitis symptoms and allergy rescue medication use during natural cat exposure.
- Trial name
- NCT04981717
- Testing
- REGN1908-1909
- Where
- 92 sites in United States, Belgium and 4 more
- Volunteers
- 446 people
- Sponsor
- Regeneron Pharmaceuticals
Macular Degeneration
Learning Study: Improving Vision in Adults With Macular Degeneration
The purpose of this study is to test whether a kind of brain stimulation called anodal transcranial direct current stimulation (a-tDCS) can be combined with perceptual learning to improve the ability of people with age-related…
- Trial name
- NCT04762368
- Testing
- Active anodal tDCS
- Where
- 2 sites in Canada, Hong Kong
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Allergic Conjunctivitis
Mast-Cell Stabilizing Effects of Olopatadine
To assess the effects of olopatadine of the release of mast cell histamine
- Trial name
- NCT00389025
- Testing
- Olopatadine (generic name)
- Where
- Italy
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Limbal Stem Cell Deficiency
Cultivated Stem Cell Transplantation for the Treatment of Limbal Stem Cell Deficiency
The purpose of this study is to determine whether cultivated stem cell transplantation is effective for the treatment of patients wtih corneal stem cell deficiency.
- Trial name
- LECT (NCT00845117)
- Testing
- Cultivated limbal stem cell graft transplantation
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- Veerle Van Gerwen
Age-Related Macular Degeneration, Choroidal Vessels; Anastomosis
Evaluation of Optical Coherence Tomography.
Determination of the sensitivity and specificity of different combinations of imaging techniques (spectral domain optical coherence tomography, fundus photography and fluorescein angiography) used for the diagnosis of choroidal…
- Trial name
- ESSO (NCT01080898)
- Testing
- tests
- Volunteers
- 151 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Headache Migraine Chronic
Spectacle Tints and Thin-Films for Migraine
Nearly all migraine sufferers report sensitivity to light during a headache and a significant proportion of sufferers report light sensitivity between attacks. Light is also a common trigger for migraine headaches.
- Trial name
- NCT02720211
- Testing
- Gray tinted spectacle lenses, Thin-Film spectacle lenses
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Allergic Rhinitis, Allergic Conjunctivitis
Olopatadine Eye Drops and Allergy Skin Testing
Use of olopatadine ophthalmic solution (eye drops) will decrease allergy skin test reactivity.
- Trial name
- NCT00775658
- Testing
- olopatadine
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Vanderbilt University Medical Center
Myopia
A Prospective Evaluation of Contrast Sensitivity and Disability Glare in Refractive Surgery, a Sub-Study of: Initial Evaluation of Excimer Laser Keratorefractive Surgery in U.S. Army Personnel (WU # 2335-99)
The purpose of this study is to conduct a prospective assessment of small target contrast sensitivity and disability glare in refractive surgery.
- Trial name
- NCT00413868
- Testing
- LASIK, PRK, Small target contrast sensitivity and disability glare
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Medical Center
Allergic Rhinoconjunctivitis
A Research Study in Chinese People With Allergy to House Dust Mites, Using an Environmental Exposure Chamber
This trial evaluates the efficacy and safety of HDM SLIT-tablet in treatment of HDM AR. The efficacy is evaluated using an environmental exposure chamber (EEC).
- Trial name
- QUEST (NCT04176185)
- Testing
- Sublingual allergy immunological tablet
- Where
- 2 sites in Austria, China
- Volunteers
- 80 people
- Sponsor
- ALK-Abelló A/S
Keratoconus, Irregular Astigmatism
Effect of Corneal and Scleral RGP Lenses on Ocular Health and Visual Quality in Keratoconus
This study aims to compare the ocular health and visual quality of corneal rigid gas permeable lenses (CRGPL) and scleral rigid gas permeable lenses (SRGPL) for patients with keratoconus in a crossover clinical trial.
- Trial name
- NCT06921967
- Testing
- Rose K2, Onefit MED
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Aarhus
Rhinitis, Allergic, Seasonal, Conjunctivitis, Allergic
Standardization of Chortoglyphus Arcuatus Allergenic Extract. Determination of Biological Activity in HEP Units
The main purpose of the trial is to prove the therapeutic value of the product and enable an effective and safe dosage schedule to be recommended
- Trial name
- NCT00718744
- Testing
- Standardization of allergenic extract (Ch. arcuatus)
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Laboratorios Leti, S.L.
Rhinitis, Allergic, Seasonal, Conjunctivitis, Allergic
Glycyphagus Domesticus Allergen Extract. Determination of the in Vivo Biological Activity in Histamine Equivalent Units (HEP).
The main purpose of the trial is to prove the therapeutic value of the product and enable an effective and safe dosage schedule to be recommended
- Trial name
- NCT00917488
- Testing
- Standardization of allergenic extract (Gly. domesticus)
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- Laboratorios Leti, S.L.
Antibiotic Side Effect, Eyelid; Wound
Topical Antibiotic Prophylaxis for Eyelids
The investigators propose a prospective randomized control trial testing the hypothesis that routine topical antibiotic prophylaxis does not significantly reduce the rate of infection after eyelid surgery.
- Conditions
- Antibiotic Side Effect, Eyelid; Wound, Eyelid Diseases, Surgical Wound Infection
- Trial name
- NCT03199911
- Testing
- Topical Antibiotic Product, Topical Non-Antibiotic Ointment
- Where
- United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cataract, Presbyopia Correction
The Purpose is to Evaluate Visual Acuity for Distance, Intermediate and Near and Additionally Contrast Sensitivity at 25% and 10% of Illumination After Implantation of Trifocal IOL, Extended Range of Vision IOL, Bifocal IOL With Low Addition and Monofocal IOL
The objective of this study was to evaluate the effect of intraocular lens (IOL) selection on visual acuity and refractive outcomes, to assess the impact of IOL type on postoperative contrast sensitivity, and to investigate…
- Conditions
- Cataract, Presbyopia Correction, Visual Acuity
- Trial name
- IOL (NCT07008768)
- Testing
- Cataract surgery and refractive lens exchange surgery, TRIFOCAL IOL, EROV IOL
- Where
- Croatia
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University Eye Hospital Svjetlost