Clinical trials: Eye Allergies
Retinopathy of Prematurity, Pain
The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination
Although screening exams for retinopathy of prematurity (ROP) prevent blindness they are physiologically stressful for infants. The investigators postulate that photosensitivity during mydriasis contributes to post-examination…
- Conditions
- Retinopathy of Prematurity, Pain, Premature Infant, Retinal Disease
- Trial name
- MASK-ROP (NCT03824782)
- Testing
- Phototherapy Mask
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Sunnybrook Health Sciences Centre
Glaucoma, Glaucoma Eye
Augmented Macular Pigment-containing Nutraceutical and Central Visual Function
The purpose of this study is to prospectively analyze changes in macular pigment optical density and dermal carotenoid levels as they relate to visual field function in patients prescribed a macular pigment-containing medical…
- Conditions
- Glaucoma, Glaucoma Eye, Glaucoma, Open-Angle
- Trial name
- NCT04676126
- Testing
- Lumega-Z, Dorzolamide Hcl 2% Oph Soln
- Where
- United States
- Sponsor
- University of the Incarnate Word
Allergic Conjunctivitis
A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and Pediatric Participants With Allergic Conjunctivitis Due to Cat Allergy
This study is researching two experimental medicines, freneslerbart and mevonlerbart. Freneslerbart and mevonlerbart can be given alone or together. When given together, the medicine is called "REGN-2Cat".
- Trial name
- NCT07675811
- Testing
- REGN-2Cat, Freneslerbart, Mevonlerbart
- Where
- United States
- Volunteers
- 570 people
- Sponsor
- Regeneron Pharmaceuticals
Allergic Conjunctivitis
Evaluation of TL-925 for the Treatment of Seasonal Allergic Conjunctivitis
In this prospective, Phase 2, randomized, double-masked, vehicle controlled study, approximately 60 eligible subjects will be randomized 1:1 to receive either TL-925 or placebo as topical ophthalmic eye drops administered…
- Trial name
- NCT07220408
- Testing
- TL-925
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Telios Pharma, Inc.
Ocular Surface Allergy, Conjunctivitis, Allergic
Treatment of Ocular Surface Inflammations
The goal of this clinical trial is to learn if topical Cyclosporine 1% works to treat severe allergic ocular surface inflammation in pediatric population.
- Conditions
- Ocular Surface Allergy, Conjunctivitis, Allergic, Blepharoconjunctivitis
- Trial name
- NCT07732855
- Testing
- Topical Cyclosporine 1%
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Ocular Surface Disease
Validation of a Newly Developed Liquid Jet Aesthesiometer
A new liquid jet aesthesiometer prototype was developed with the aim to measure ocular surface sensitivity by employing a liquid jet.
- Trial name
- NCT02999035
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts Northwestern Switzerland
Age Related Macular Degeneration, Choroidal Neovascularization
Sensitivity of the Home Macular Perimeter (HMP)
estimate the sensitivity of the HMP test in identifying visual field functional defects in subjects with CNV secondary to AMD
- Trial name
- HMP (NCT00604071)
- Where
- 10 sites in United States
- Volunteers
- 99 people
- Sponsor
- Notal Vision Ltd.
Allergic Conjunctivitis
Alleviation of Cedar Pollen Induced Allergic Symptoms by Orally Taken Superfine Beta-1,3-Glucan
Intravenous- injection of beta-1,3-glucan in human is known to induce T helper type 1 response, while oral uptake did not. It was examined whether superfine dispersed beta-1,3-glucan (SDG) contrived to absorbed by intestinal…
- Trial name
- NCT00276445
- Testing
- beta-1,3-glucan
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Meiji University of Oriental Medicine
Allergic Conjunctivitis
Evaluation of the Effect and Tolerance of Preservative Free NAAGA on the Inflammatory Component and Symptoms of Dry Eye Syndrome in Allergic Conjunctivitis Patients
Multicentre, Double blind, Randomized, Comparative Study(comparing N-acetyl-aspartyl-glutamic acid(NAAGA) in Abak preservative free device versus SALINE in Abak preservative free device.
- Trial name
- NCT01203540
- Testing
- NAABAK eyedrops, Saline eyedrops
- Where
- 2 sites in South Korea
- Volunteers
- 21 people
- Sponsor
- Laboratoires Thea
Chronic Inflammatory Disease, Angioedema
Deployment o the Multidisciplinary Prospective Cohort Imminent
Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and…
- Conditions
- Chronic Inflammatory Disease, Angioedema, Severe Asthma, Lupus
- Trial name
- IMMINeNT (NCT04334031)
- Testing
- Biobanking with genetic analysis, SF-12 questionnaire
- Where
- France
- Volunteers
- 2,200 people
- Sponsor
- University Hospital, Lille
Atopic Dermatitis, Food Hypersensitivity
Use of Probiotic Bacteria in Prevention of Allergic Disease in Children 1999-2008
The aim of the study is to find out if allergic diseases can be prevented buy giving probiotic bacteria to pregnant mothers and their newborn infants
- Conditions
- Atopic Dermatitis, Food Hypersensitivity, Allergic Rhinitis, Seasonal, Allergic Conjunctivitis
- Trial name
- NCT00298337
- Testing
- Mixture of probiotic bacteria and prebiotic oligosaccharide
- Where
- Finland
- Sponsor
- University of Helsinki
Allergic Conjunctivitis
A Patient Reported Ocular Comfort Assessment Comparing Bepreve to Lastacaft
The purpose of this study is to evaluate the comfort of BEPREVE compared to LASTACAFT after instillation.
- Trial name
- NCT01339507
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cunningham, Derek N., O.D., P.A.
Rhinitis Allergic, Conjunctivitis
A Study of SCH 697243 in Participants With Grass Pollen Allergy Symptoms, With or Without Asthma (P08067)
This is a study to evaluate the efficacy and safety of grass sublingual tablet (SCH 697243) versus placebo in the treatment of grass pollen-induced allergic hayfever symptoms.
- Trial name
- NCT01385371
- Testing
- Grass (Phleum pratense) pollen allergen extract
- Volunteers
- 1,501 people
- Sponsor
- ALK-Abelló A/S
Stevens-Johnson Syndrome
Efficacy of 0.05% Cyclosporin Eye Drop in Stevens Johnson Syndrome Patient With Chronic Dry Eye
The purpose of this study is to evaluate the efficacy of 0.05% cyclosporin ophthalmic emulsion (Restasis) in patients with Stevens-Johnson syndrome that have dry eyes by subjective symptoms and signs.
- Trial name
- NCT01488396
- Testing
- 0.05%cyclosporin eye drop
- Where
- Thailand
- Volunteers
- 31 people
- Sponsor
- Mahidol University
Allergic Conjunctivitis
Efficacy and Safety of an Ophthalmic Solution in Patients With Allergic Conjunctivitis
The purpose of this study is to evaluate an ophthalmic solution for the treatment of ocular itching associated with allergic conjunctivitis using the Conjunctival Allergen Challenge (CAC) model.
- Trial name
- NCT01743027
- Testing
- AL-4943A ophthalmic solution, Olopatadine hydrochloride ophthalmic solution, 0.2%, Olopatadine hydrochloride ophthalmic solution, 0.1%
- Volunteers
- 902 people
- Sponsor
- Alcon Research
Allergic Conjunctivitis
Confocal Analysis of Corneal Structures of Symptomatic Allergic Conjunctivitis Patients
The purpose of this study is to descriptively evaluate the corneal structures of allergic conjunctivitis patients.
- Trial name
- NCT01697969
- Testing
- Olopatadine hydrochloride ophthalmic solution, 0.2%
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Alcon Research
Nervous System Malformations, Arthropathy, Neurogenic
Anakinra to Treat Patients With Neonatal Onset Multisystem Inflammatory Disease
This study will evaluate the safety and effectiveness of anakinra (Kineret) for treating patients with neonatal-onset multisystem inflammatory disease (NOMID), also known as chronic infantile neurological, cutaneous and…
- Conditions
- Nervous System Malformations, Arthropathy, Neurogenic, Urticaria, Papilledema
- Trial name
- NCT00069329
- Testing
- anakinra
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Atopic Dermatitis
Ophthalmological Adverse Events of Tralokinumab in AD
Atopic dermatitis (AD) is a skin disease characterised by xerosis, pruritus and erythematous plaques. It is common in children (10 to 20%) with an increasing prevalence (multiplied by 2 in 20 years) and begins to develop at 3…
- Trial name
- TRALO-Oeil (NCT05682976)
- Where
- 11 sites in France
- Volunteers
- 100 people
- Sponsor
- Nantes University Hospital
Cataract
Evaluating Patient Satisfaction After Cataract Surgery With Multifocal Intraocular Lens
Multifocal lens allow most patients to be spectacle-free after cataract surgery. Most studies published up-to-date have focused on visual acuity, but not on patient-reported outcomes.
- Trial name
- NCT03787576
- Testing
- Cataract surgery
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Clínica Rementería
Allergic Conjunctivitis
Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis
Allergic conjunctivitis (AC) afflicts approximately 20% of the US population. Typically, patients manifest symptoms in the spring, summer and fall, when airborne allergens are at their peak.
- Trial name
- NCT01443442
- Testing
- bepotastine besilate, 1.5%, Loteprednol etabonate
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University