Clinical trials: Eye Disease; Cataract
Cataract With Exfoliation Syndrome
Efficacy of a Capsular Tension Ring in Preventing Anterior Capsule Shrinkage After Cataract Surgery in Exfoliation Syndrome
The purpose of this study is to examine the efficacy of a capsular tension ring (CTR) in preventing anterior capsule shrinkage after cataract surgery in exfoliation syndrome (XFS) with no zonular weakness.
- Trial name
- Effect of CTR (NCT01455168)
- Where
- Japan
- Volunteers
- 30 people
- Sponsor
- University of Occupational and Environmental Health
Fuchs' Endothelial Dystrophy, Cataract
Using the Optovue OCT to Select IOL Power
Many patients with endothelial dysfunction also present with cataracts. It is therefore common practice to perform cataract extraction and intraocular lens (IOL) implantation during the same operation and immediately prior to…
- Trial name
- NCT01361282
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Legacy Health System
Posterior Capsule Opacification
An Innovative Method Fluid-jet to to Remove Residual Lens Fibers
Residual lens fibers (RLFs) on the posterior lens capsule during cataract surgery can cause after cataract, affecting visual quality and increasing the medical cost for further laser posterior capsulotomy.
- Trial name
- NCT03605160
- Testing
- traditional polish, fluid-jet
- Where
- China
- Volunteers
- 740 people
- Sponsor
- Sun Yat-sen University
Cataract
Computer-based Tutorial for the Informed Consent Process for Cataract Surgery in Turkish or Serbian Speaking Patients
Investigate if a computer-based tutorial enhances the quality and efficiency of the informed consent process for cataract surgery in Turkish or Serbian speaking patients.
- Trial name
- NCT03748368
- Testing
- Cataract presentation
- Where
- Austria
- Volunteers
- 72 people
- Sponsor
- Prim. Prof. Dr. Oliver Findl, MBA
Glaucoma, Cataract
Effect of Elevated Intraocular Pressure in Glaucoma Patients During Femtolaser Cataract Surgery
The use of the femtosecond laser causes an increase in the intraocular pressure (IOP) between 100 mm Hg and 200 mm Hg for a period of about 80 seconds (suction phase).
- Trial name
- FEMTOHTO (NCT02835482)
- Testing
- Femtolaser surgery, Phacoemulsification
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Glaucoma, Open-Angle
Open-Angle Glaucoma Subjects With Cataract Treated With Cataract Surgery Plus One iStent and One iStent Supra
Open Angle Glaucoma Subjects with Cataract treated with Cataract Surgery plus one trabecular micro-bypass stent and one suprachoroidal stent
- Trial name
- NCT03255785
- Testing
- Cataract surgery plus one iStent and one iStent Supra implanted
- Where
- Armenia
- Volunteers
- 15 people
- Sponsor
- Glaukos Corporation
Cataract
Evaluation of the EpiGlare Tester for the Measurement of Glare-Induced Changes in BSCVA in Subjects With and Without Cataracts
The EpiGlare Tester will identify visual disability resulting from the glare experienced by subjects with cataracts in the glare-induced change in best spectacle corrected visual acuity (BSCVA).
- Trial name
- NCT04739397
- Testing
- Glare Testing
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Epico, LLC
Cataracts
Comparing Optical Coherence Tomography (OCT) and Visual Acuity Outcomes in Subjects Undergoing Cataract Surgery, Who Receive Xibrom Ophthalmic Solution and Standard Presurgical Care vs. Xibrom Ophthalmic Solution Plus Prednisolone Acetate 1% and Standard Presurgical Care
To compare the efficacy of twice-daily topical bromfenac (Xibrom) ophthalmic solution alone versus twice-daily topical Xibrom with prednisolone acetate 1% three-times daily on visual acuity and OCT measurements.
- Trial name
- NCT00698724
- Testing
- Xibrom, and Optive, Xibrom and Pred Forte
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bp Consulting, Inc
Cataract
A Post-Market Clinical Follow-Up on Safety and Performance of the Ophthalmic Viscoelastic Devices Eyefill SC and Eyefill MB
Prospective, Non-comparative, Post Market Clinical Follow Up Study to demonstrate safety and performance of Eyefill® S.C. and Eyefill® M.B. as viscoelastic devices for cataract surgery
- Trial name
- NCT06767917
- Testing
- Eyefill® S.C., Eyefill® M.B.
- Where
- 2 sites in Spain
- Volunteers
- 148 people
- Sponsor
- Bausch & Lomb GmbH
Cataract
Developmental Profile of Ocular Refraction in Patients With Congenital Cataract
The purpose of prospective cohort study is to describe the developmental profile of refraction change in a large cohort of Chinese CC patients.
- Trial name
- NCT02761850
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Sun Yat-sen University
Inflammation
Study of Difluprednate Ophthalmic Emulsion in the Treatment of Postoperative Inflammation
The purpose of this phase 2 study is to determine if difluprednate ophthalmic emulsion is effective in the treatment of postoperative inflammation.
- Trial name
- NCT00407225
- Testing
- Difluprednate Ophthalmic Emulsion
- Volunteers
- 24 people
- Sponsor
- Sirion Therapeutics, Inc.
Ocular Inflammation
KPI-121 1% Versus Prednisolone for the Treatment of Inflammation Following Cataract Surgery in Children
This study is designed to assess how KPI-121 1% compares to prednisolone acetate in reducing inflammation after cataract surgery in young children.
- Trial name
- NCT03596723
- Testing
- KPI-121 1%, Prednisolone acetate
- Where
- 4 sites in United States
- Volunteers
- 2 people
- Sponsor
- Kala Pharmaceuticals, Inc.
Cataract
Effect of Blue Light Filtration on Visual Performance
The purpose of this study is to evaluate photostress recovery with blue light filter clip-on glasses among pseudophakes [ie, subjects in which the natural lens of the eye has been replaced with an artificial lens (intraocular…
- Trial name
- NCT01938989
- Testing
- Clear clip-on glasses, Blue light filter clip-on glasses
- Volunteers
- 158 people
- Sponsor
- Alcon Research
Cataract
A Study Assessing the Safety and Efficacy of Dextenza® for the Treatment of Ocular Pain and Inflammation Following Surgery for Pediatric Cataract
To assess the safety of Dextenza compared to an active control, prednisolone acetate suspension, for the treatment of postoperative pain and inflammation following ocular surgery for pediatric cataract.
- Trial name
- NCT04539548
- Testing
- Dextenza Ophthalmic Insert, Prednisolone acetate ophthalmic suspension USP 1%
- Where
- 14 sites in United States
- Volunteers
- 65 people
- Sponsor
- Ocular Therapeutix, Inc.
Cataract, Aphakia
Clareon Toric vs Eyhance Toric
The primary purpose of this study is to compare the Clareon/Clareon Toric Intraocular Lenses (IOLs) to the Eyhance/Eyhance Toric IOLs in binocular Best Corrected Distance Visual Acuity (BCDVA) at 3 months postoperative.
- Trial name
- NCT05481125
- Testing
- Clareon IOL, Clareon Toric IOL, Eyhance IOL
- Where
- 8 sites in United States
- Volunteers
- 203 people
- Sponsor
- Alcon Research
Cataract
Effects of Oxygen Cage Support During Cataract Surgery
Cataract is an ocular disorder resulting from lens opacity; it stands as the most common cause of preventable blindness worldwide and significantly impairs the quality of life in elderly individuals.
- Trial name
- NCT07632326
- Testing
- Oxygen Support Cage
- Volunteers
- 70 people
- Sponsor
- Ataturk University
Cataract, Analgesia
Analgetic Effect of Two Solutions of Intracameral Anesthesia During Cataract Surgery in Patients
Purpose: The aim of the study was to compare the analgetic effect of two solutions of intracameral anesthesia in patients undergoing cataract surgery and assess the factors influencing the patients' postoperative activities.
- Conditions
- Cataract, Analgesia, Ophthalmological Disorder
- Trial name
- NCT04166578
- Testing
- lignocaine, Phacoemulsyfication, Intraocular lens implantation
- Where
- Poland
- Volunteers
- 62 people
- Sponsor
- Medical University of Lublin
Cataract
Evaluation of Therapeutic Strategies in Pediatric Cataract Surgery
The purpose of this observational study is to assess the therapeutic strategies in the treatment of pediatric cataracts.
- Trial name
- EP3C (NCT02253017)
- Testing
- Children operated on for cataract
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cataract, Inflammation
Indomethacin Eyedrops Compared With Ketorolac Eyedrops for Ocular Inflammation Following Cataract Surgery
This study is being conducted to show that indomethacin is at least as effective as ketorolac for the prevention of ocular inflammation following cataract surgery.
- Trial name
- NCT00904904
- Testing
- Indomethacin ophthalmic solution, Ketorolac Ophthalmic Solution
- Where
- Germany
- Volunteers
- 120 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract, Anxiety
Impact of Music Therapy on Intraoperative Patient Comfort During Cataract Surgery With Topic Anesthesia
Cataract surgery with topic anesthesia is anxiety provoking. This operative stress can increase pain perception and blood pressure.
- Trial name
- NCT04819750
- Testing
- MusicCare® device, Headphones with noise reduction
- Volunteers
- 350 people
- Sponsor
- University of Liege