Clinical trials: Eye Fatigue
Sjögren Syndrome
Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sjogren's Syndrome
This study was to evaluate the safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple doses of CFZ533 (iscalimab) in patients with Sjögren's Syndrome (SjS).
- Trial name
- TWINSS (NCT03905525)
- Testing
- CFZ533
- Where
- 71 sites in United States, Argentina and 21 more
- Volunteers
- 273 people
- Sponsor
- Novartis Pharmaceuticals
Accommodation Disorder, Keratoconus
Clinical Investigation for a Multifunction Ophthalmic Measurement Device
The purpose of this clinical investigation is to evaluate the clinical utility of a multifunctional measuring device for Ophtalmology.
- Conditions
- Accommodation Disorder, Keratoconus, Dry Eye, Refractive Errors
- Trial name
- NCT06565091
- Testing
- Measurements of physiological parameters of the anterior chamber, Measurements of the Axial biometry
- Where
- France
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Essilor International
Dry Eye, Eye Fatigue
A Randomized Controlled Trial to Evaluate the Safety and Efficacy of an Oral Supplement in Supporting Vision and Eye Health
This is a 4-week virtual randomized, triple-blinded, placebo-controlled clinical trial evaluating the safety and efficacy of Eye Empower, an oral supplement, in adults aged 45 or older experiencing dry eyes, irritation, and…
- Trial name
- NCT07123584
- Testing
- Eye Empower
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bio Nature Health
Astigmatism
Toric Eye Strain and Stability Study
The purpose of this study is to determine the benefits of fitting low astigmats with soft toric contact lenses versus spherical contact lenses with regard to visual comfort, eyestrain, fitting efficiency, and visual performance.
- Trial name
- NCT01857102
- Testing
- etafilcon A, etafilcon A for Astigmatism
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Sleep Deprivation, Sleepiness
Shift Hours' Impact on Fatigue and Tracking of Eye Dynamics
The goal of this clinical trial is to learn how night shift-induced sleep debt affects oculomotor patterns, attentional state, and diagnostic performance in emergency radiologists.
- Conditions
- Sleep Deprivation, Sleepiness, Eye-Tracking Technology, Radiologists
- Trial name
- SHIFTED (NCT07192380)
- Testing
- Electroencephalogram, Actigraphy, Eye Tracking
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- IMADIS Technologies et Services
Myopia, Dry Eye Disease (DED)
Study of Eye Fatigue From Digital Screens and Its Impact on Visual Performance in People With Normal Vision and Myopia, With and Without Dry Eye Symptoms and Signs
The goal of this observational study is to investigate the effects of eye fatigue induced by screen task on dry eye disease (DED) signs and symptoms, visual performance, and visual behavior in young adults with and without DED…
- Trial name
- RReye (NCT07844408)
- Testing
- Eye Exams, Ocular Biometry and Aberrometry, Wearing a Smartwatch
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Essilor International
Evaporative Dry Eye
Impact of Tear Substitute Use on Dry Eye in Gamers.
Clinical, prospective, comparative, controlled, single-blind study, on the signs and symptoms of dry eye before and after 3 days of playing video games with the use of artificial tears (Hyabak) versus no intervention.
- Trial name
- HYAGAME (NCT05536661)
- Testing
- Preservative free hyaluronic acid artificial tear
- Where
- Spain
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Laboratorios Thea, Spain
Digital Eye Strain (DES)
Lactic Acid Bacteria for Reducing Blue Light-Induced Eye Fatigue
With the widespread use of digital devices and prolonged screen exposure, digital eye strain (DES), also known as computer vision syndrome, has become a global public health concern.
- Trial name
- NCT07737938
- Testing
- BL531_low dose, BL531_high dose, LR1349_low dose
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Synbio Tech Inc.
Eye Strain, Eye Strain of Both Eyes
Study of Non-inferiority Between Manzanilla Sophia® and Meticel Ofteno® 0.5% for Providing a Soothing Sensation to the Eyes.
This is a phase IV clinical study to demonstrate the non-inferiority of Manzanilla Sophia® compared to Meticel Ofteno® 0.5% in providing restful sensation to the eyes.
- Trial name
- NCT06373653
- Testing
- Manzanilla Sophia®, Meticel Ofteno®
- Volunteers
- healthy volunteers welcome
- Sponsor
- Laboratorios Sophia S.A de C.V.
Dry Eye Disease Associated to Asthenopia and Accommodative Effort in Video Display Terminal Users
Evaluation of Performance and Safety of Eye Drops With Hydroxypropyl-methylcellulose and Inositol in Drye Eye Disease
This is a profit, multicentric, prospective, single-arm, open-label, non-pharmacological clinical investigation. Patients with diagnosis of moderate to severe dry eye disease with asthenopia and accommodative effort will receive…
- Trial name
- NCT06190054
- Testing
- MERAMIRT
- Where
- 4 sites in Italy
- Volunteers
- 100 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Dry Eye, Asthenopia
Evaluate the Safety and Efficacy of Calcitonin Gene-Related Peptide (CGRP) Antagonists in Patients With Dry Eye Disease and Asthenopia
Safety and Efficacy of Medications for Migraine in Patients with Dry Eye Disease or Asthenopia
- Trial name
- NCT05895500
- Testing
- Injection for SC administration (120mg/syringe), Tablet (50mg/tablet), oral
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Nvision Laser Eye Centers
Dry Eye Disease (DED)
Vizol S DIGI EYE Efficacy and Safety Study in Patients With Dry Eye
The clinical investigation was intended to investigate the efficacy, ocular tolerability and safety of Vizol S DIGI EYE, a new eye drops, solution developed by JADRAN - GALENSKI LABORATORIJ d.d., in patients with moderate to…
- Trial name
- NCT07050446
- Testing
- Vizol S DIGI EYE eye drops, 0,9% saline solution, eye drops
- Where
- 3 sites in Serbia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Jadran Galenski laboratorij d.d.
Wrinkle, Fatigue
Anti-ageing Efficacy of a Cosmetic Formulation Containing NMN (2%) Versus Placebo
The study aims at evaluating skin wrinkling, puffiness and fatigue and dark circle appearance on asian and african-american healthy volunteer cohorts receiving a cosmetic formulation containing NMN (2%).
- Conditions
- Wrinkle, Fatigue, Puffiness Around the Eyes
- Trial name
- NCT04685096
- Testing
- Test product creme, Reference creme
- Where
- 2 sites in United States, China
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Seneque SA
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Vision Disorders
To Evaluate the Efficacy and Safety of CAEP-01 on Eye Strain in Children With Heavy Screen Use
Several recent clinical trials have highlighted the potential role of Product in promoting eye health.product whose structural and functional characteristics make it a promising bioactive compound in the prevention of several…
- Trial name
- NCT05602402
- Testing
- CAEP-01
- Where
- 3 sites in India
- Volunteers
- 64 people
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Burning Eye, Irritation; Eyeball
Vit-A-Vision® Clinical Investigation
Symptoms of ocular discomfort include dryness, burning, stinging, photophobia, foreign body sensation and contact lens intolerance.
- Conditions
- Burning Eye, Irritation; Eyeball, Tired Eye, Dry Eye Disease
- Trial name
- NCT06596733
- Testing
- Vit-A-Vision
- Where
- Germany
- Volunteers
- 77 people
- Sponsor
- OmniVision GmbH
Sjögren´s Disease
Two Arm, Double-blind, Phase III Study Assessing Efficacy and Safety of Ianalumab Versus Placebo, in Participants With Sjögren's Disease With High Symptom Burden
The purpose of this study is to demonstrate the efficacy and safety of ianalumab (VAY736) 300 mg administered subcutaneously (s.c.) monthly for 52 weeks in adult participants with Sjögren's disease who have high symptom burden.
- Trial name
- THALASSA (NCT07621809)
- Testing
- VAY736
- Where
- 33 sites in United States, Australia and 6 more
- Volunteers
- 570 people
- Sponsor
- Novartis Pharmaceuticals
Lymphoma
Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)
To understand the safety and efficacy of Revlimid® Capsules 2.5 mg and 5 mg (hereinafter referred to as Revlimid) under actual conditions of use in patients with relapsed or refractory adult T-cell leukemia lymphoma (hereinafter…
- Trial name
- NCT03098589
- Testing
- Revlimid
- Where
- Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Refractive Ametropia, Myopia
Comparison of Two Daily Disposable Lenses
The purpose of this study was to compare the clinical performance of the new DAILIES® AquaComfort PLUS® FreshTech (DACP FreshTech) contact lenses to an already marketed daily disposable contact lens, DAILIES® AquaComfort PLUS®…
- Trial name
- NCT04013789
- Testing
- DACP FreshTech contact lenses, DACP contact lenses
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Alcon Research
Dry Eye Symptom, Eye Fatigue
Effects and Safety of Steam Eye Mask With Acupoints Stimulation
To evaluate the effects and safety of the steam eye mask with acupoints stimulation by the moist heat of approximately 40 degree C for 20 minutes and massage acupoints on eyebrows for eye fatigue, dry eye symptoms and…
- Trial name
- NCT04584216
- Testing
- Steam Eye Mask with acupoints stimulation, Steam Eye Mask
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kao (Taiwan) Corporation