Clinical trials: Eye Manifestations
Headache, Acute, Focal Neurologic Disease
Digital Ocular Fundus Photography in the Emergency Department: A New Application for Telemedicine?
The purpose of this study is to determine if non-dilated retinal photography in the emergency room improves the diagnosis of papilledema (optic nerve swelling) in patients with neurologic disease compared to direct ophthalmoscopy.
- Conditions
- Headache, Acute, Focal Neurologic Disease, Severely Elevated Blood Pressure, Acute Visual Loss
- Trial name
- NCT00873613
- Testing
- Use of Non-dilated retinal photography
- Where
- United States
- Volunteers
- 705 people
- Sponsor
- Emory University
CHARGE Syndrome
A Strategic Approach to Safe and Effective Cochlear Implantation in Patients With CHARGE Syndrome
This retrospective observational study aims to evaluate cochlear anatomy, surgical challenges, and strategic approaches for safe cochlear implantation in pediatric patients with CHARGE syndrome.
- Trial name
- NCT07320482
- Testing
- No intervention (observational study)
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Seoul National University Bundang Hospital
Visual Rehabilitation, Visual Impairment, Autism Spectrum Disorder, Developmental Disabilities, Intellectual Disability, Behavioral Symptoms
Evaluation of a Program to Enhance Ophthalmic Compliance in Children and Adolescents With Special Needs
The goal of this clinical trial is to learn about the effects of the structured program incorporating contextual, behavioral, and cognitive strategies to improve compliance of children and adolescents with special needs during…
- Trial name
- NCT06717282
- Testing
- visual rehabilitation for ophthalmic compliance, Using contextual, behavioral, and cognitive-based stragegies to develop training programs
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Low Vision
Orthoptic Rehabilitation for Low Vision People With Innovative Mechanisms (Eye Tracker and Tactile Device)
This project is working on orthoptic rehabilitation for low vision people. The aim of the project is to assess the interest and integration of this rehabilitation device used at home, in low-vision private practice and at the…
- Trial name
- VISIONUM (NCT03353727)
- Testing
- Orthoptic rehabilitation
- Where
- 3 sites in France
- Volunteers
- 12 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Trauma, Infections
Ophthalmological Emergencies and COVID-19 Pandemia
To analyze how the COVID 19 pandemia has affected the patient's accesses to the Ophthalmological Emergency Department of a tertiary referral center in northern Italy, during the lockdown period.
- Conditions
- Trauma, Infections, Vision; Loss, Both Eyes
- Trial name
- NCT05065788
- Testing
- data collection
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Università degli Studi dell'Insubria
Post-operative Pain, Irreversible Pulpitis
Relationship of Eye Colour With Anesthetic Success and Post-Operative Pain
Current evidence indicates that some phenotypic characteristics, such as eye or hair color, might be associated with the experience of pain.
- Trial name
- NCT06206304
- Testing
- Root canal therapy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Glaucoma
Is the RAPDx Pupillograph Able to Distinguish Between Glaucoma Subjects and Healthy Subjects?
The Konan RAPDx (Konan Medical USA, Irvine, CA) is a newly patented pupillography device.The aims of this study are to assess the ability of the RAPDx to distinguish between healthy subjects and patients with confirmed glaucoma…
- Trial name
- NCT02526693
- Testing
- Pupillometer
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Wills Eye
Fuchs Dystrophy, Endothelial Corneal Dystrophy
The ADVISE Study: Advanced Visualization In Corneal Surgery Evaluation
Rationale: Intra-operative optical coherence tomography (iOCT) is a new technology that incorporates advanced imaging techniques in the ophthalmic operating theatre.
- Conditions
- Fuchs Dystrophy, Endothelial Corneal Dystrophy, Bullous Keratopathy, Vision Disorders
- Trial name
- ADVISE (NCT03763721)
- Testing
- intraoperative optical coherence tomography (iOCT)
- Where
- 3 sites in Belgium, Netherlands
- Volunteers
- 65 people
- Sponsor
- UMC Utrecht
Wegener Granulomatosis, Microscopic Polyangiitis
Vasculitis Illness Perception (VIP) Study
The purpose of this study is to learn about how patients with vasculitis think about their illness and to assess to what extent patient perceptions of illness are associated with physical, mental, and social functioning
- Conditions
- Wegener Granulomatosis, Microscopic Polyangiitis, Churg-Strauss Syndrome, Polyarteritis Nodosa
- Trial name
- NCT02190916
- Where
- United States
- Volunteers
- 707 people
- Sponsor
- University of South Florida
Amblyopia
Virtual Reality Game Playing in Amblyopia Therapy
Background: "Amblyopia is a neurodevelopmental disorder in both monocular and binocular functions and it extends even beyond the primary visual integration centers", therefore, amblyopia is not a "lazy eye" but it is a "lazy…
- Trial name
- NCT04261868
- Testing
- Virtual Reality, Patching
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hamideh Sabbaghi
Age - Related Macular Degeneration, Diabetic Retinopathy
A Comparison of the Checkup Vision Assessment System to Standard Vision Assessment Tools
The CLEAR study is testing the level of agreement between visual acuity and Amsler grid testing using a mobile vision testing application, Checkup Study, and standard in office methods.
- Conditions
- Age - Related Macular Degeneration, Diabetic Retinopathy, Metamorphopsia
- Trial name
- CLEAR (NCT02871817)
- Testing
- Paxos Checkup Study Mobile Medical Application
- Where
- 12 sites in United States
- Volunteers
- 143 people
- Sponsor
- Digisight Technologies, Inc.
Low Flow Anesthesia, Sevoflurane
Low Flow Anesthesia in Children Undergoing Strabismus Surgery
Emergence agitation (EA) involves restlessness, disorientation, excitation, non-purposeful movement, inconsolability, thrashing, and incoherence during early recovery from general anesthesia.
- Conditions
- Low Flow Anesthesia, Sevoflurane, Strabismus, Emergence Delirium
- Trial name
- LFA in child (NCT06560268)
- Testing
- Sevoflurane; In our study, the effects of sevoflurane in different FGFs administered in children undergoing strabismus surgery on EA and anesthetic agent consumption will be investigated.
- Volunteers
- 150 people
- Sponsor
- Cukurova University
Idiopathic Intracranial Hypertension
Surgical Idiopathic Intracranial Hypertension Treatment Trial
Randomized trial of adults (≥18 years old) with idiopathic intracranial hypertension and moderate to severe visual loss without substantial recent treatment who are randomly assigned to (1) medical therapy, (2) medical therapy…
- Trial name
- SIGHT (NCT03501966)
- Testing
- Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting
- Where
- 36 sites in United States, Canada and 1 more
- Volunteers
- 7 people
- Sponsor
- Jaeb Center for Health Research
Amblyopia
Treating Amblyopia in Adults With Interactive Video Games
Researchers are trying to determine whether interactive video game play, while wearing a patch over better-seeing eye, will improve subject reduced vision (amblyopia).
- Trial name
- NCT03906994
- Testing
- Video game Mario Kart Wii
- Sponsor
- Mayo Clinic
Amblyopia
Docosahexaenoic Acid (DHA) Supplementation in Amblyopia
This study evaluates the addition of docosahexaenoic acid (DHA) to eye patching in the treatment of residual amblyopia in children ages 3 to 18 years old.
- Trial name
- NCT03402789
- Testing
- Docosahexaenoic Acid
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cataracts
Endothelial Cell Loss After Cataract Surgery
The purpose of this study is to compare two cataract surgical technique variations for removing the nucleus of the lens (central part of the lens) in terms of damage to the inner layer of the cornea which is called the…
- Trial name
- NCT00932191
- Testing
- Standard phacoemulsification, Reduced ultrasound phacoemulsification
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Francisco
Amblyopia
Novel Amblyopia Treatment With Virtual Reality Games
The goal of this study is to compare the change in amblyopic eye acuity between treatment periods in children with amblyopia, aged 5-17 years.
- Trial name
- NCT06049459
- Testing
- Optical Correction, Therapeutic Dichoptic Virtual Reality Games
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Marjean Kulp
Age-related Macular Degeneration, Dementia
Words on the Brain: Can Reading Rehabilitation for Age-Related Vision Impairment Improve Cognitive Functioning?
Age-related vision impairment and dementia both become more prevalent with increasing age. Research into the mechanisms of these conditions has proposed that some of their causes (e.g., macular degeneration/glaucoma and…
- Conditions
- Age-related Macular Degeneration, Dementia, Low Vision, Low Vision Aids
- Trial name
- WOTB (NCT04276610)
- Testing
- Low Vision Reading Rehabilitation
- Where
- 2 sites in Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Pupillary Disorders
Correlation of Pupillary Diameter Changewith Age and Anterior Chamber Depth After Cataract Surgery
PURPOSE: To assess the correlation between the change in pupil diameter, age and depth of the anterior chamber after 3 months of cataract surgery both in photopic and mesopic conditions.
- Trial name
- NCT04286646
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- Clinica Oftalmologica TACIR
Age-related Macular Degeneration, Low Vision
Automatic Self Transcending Meditation (ASTM) for Patients With Severe Age Related Macular Degeneration (AMD)
Age-related macular degeneration (AMD) is a condition affecting 20 to 25 million people worldwide. Symptoms of AMD includes difficulty in reading, recognizing faces and completing house work which may result in increased…
- Trial name
- NCT03104608
- Testing
- Automatic Self Transcending Meditation, Treatment as Usual
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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