Clinical trials: Eye--Refractive Errors
Presbyopia
Clinical Evaluation of Biofinity Multifocal Compared With Air Optix Aqua Multifocal and With PureVision Multifocal
This is a prospective, multi-centre, randomised, single-blind, cross-over study to compare the BIOFINITY® MULTIFOCAL lens and respectively the AIR OPTIX® AQUA MULTIFOCAL lens (lenses allocated on a ratio of 1/0.5) and the…
- Trial name
- INNOVATION (NCT01591499)
- Testing
- BIOFINITY® MF - AIR OPTIX® AQUA MF, BIOFINITY® MF - PUREVISION® MF
- Volunteers
- 142 people
- Sponsor
- CooperVision, Inc.
Cataract, Corneal Astigmatism
Post-market Study to Obtain Surgeon Feedback on Clinical Outcome in Eyes Implanted With TECNIS Toric II IOL
This is a multicenter, prospective, single-arm, open-label, clinical study of the commercially available TECNIS Toric II, Model ZCU IOL.
- Trial name
- NCT04210232
- Testing
- TECNIS® TORIC II Intraocular Lens (IOL)
- Where
- 12 sites in United States
- Volunteers
- 54 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Myopia, Amblyopia
Myopia Control With Three Lever Irradiance of PBM Therapy in Children and Adults
Photobiomodulation therapy, that is, Low-level red-light technology provides a new and innovative myopia control approach. This strategy enables relatively high energies of light to be delivered at much shorter durations of…
- Conditions
- Myopia, Amblyopia, Refractive Error - Myopia Axial, Ametropia
- Trial name
- MCPT (NCT05957458)
- Testing
- Airdoc device of red light for Myopia
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Beijing Airdoc Technology Co., Ltd.
Myopia
The Clinical Comparison of Narafilcon A and Stenfilcon A Contact Lenses
This study aims to compare the clinical performance and subjective acceptance of the narafilcon A lens with the stenfilcon A lens when used on a daily wear, daily disposable basis.
- Trial name
- NCT02920970
- Testing
- narafilcon A, stenfilcon A
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Myopia
Clinical Comparison of Silicone Hydrogel and HEMA-based Daily Disposable Contact Lenses
The purpose of this trial was to compare the performance of an investigational daily disposable contact lens to a commercially available daily disposable contact lens.
- Trial name
- NCT01362907
- Testing
- Delefilcon A contact lens, Etafilcon A contact lens
- Volunteers
- 40 people
- Sponsor
- CIBA VISION
Myopia
Myopia Progression After Ceasing Myopia Control Contact Lens Wear
This is a continuation study for subjects who were previously fit with test or control lenses; all will stop wearing their study lenses assigned in the previous study and will start to wear an FDA-approved marketed spherical soft…
- Trial name
- NCT01829230
- Testing
- 1 Day Acuvue Moist
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Errors
Clinical Performance of a Monthly Replacement Silicone Hydrogel Lens
The purpose of this study is to assess the clinical performance of an investigational, coated silicone hydrogel contact lens over approximately 30 days of daily wear.
- Trial name
- NCT03586167
- Testing
- LID014341 contact lenses, Comfilcon A contact lenses
- Where
- 4 sites in United States
- Volunteers
- 88 people
- Sponsor
- Alcon Research
Myopia, Dry Eye
Effect of Contact Lenses on Tear Osmolarity in a Controlled Low Humidity Chamber
The purpose of this study is to evaluate two different types of contact lenses and their effect on dry eyes when compared to wearing glasses in a controlled, low humidity chamber.
- Trial name
- NCT01482312
- Testing
- lotrafilcon A contact lenses, comfilcon A contact lenses, Glasses
- Where
- Canada
- Volunteers
- 29 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
High Refractive Index Material 510(k)
The purpose of this study is to establish the substantial equivalence of the HDS HI 1.54™ to the paflufocon C material control lenses to correct myopia and hyperopia with and without astigmatism.
- Trial name
- PVS-07-07 (NCT00766168)
- Testing
- HDS HI 1.54; pahrifocon A, FluoroPerm 30 RGP; paflufocon C
- Where
- 8 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Astigmatism
A Clinical Comparison of Two Soft Toric Contact Lenses
The aim of this study is to compare the short-term clinical performance of two toric contact lenses.
- Trial name
- NCT06758089
- Testing
- Lens 1 (ocufilcon D), Lens 2 (somofilcon A)
- Where
- United Kingdom
- Volunteers
- 42 people
- Sponsor
- CooperVision International Limited (CVIL)
Presbyopia, Refractive Error
DAILIES® AquaComfort Plus® Multifocal (MF) - Comparative Assessment of Visual Performance
The purpose of this study is to evaluate the visual performance of DAILIES® Aqua Comfort Plus® (DACP) MF contact lens using new objective measurements.
- Trial name
- NCT02235831
- Testing
- Nelfilcon A MF contact lenses (DACP MF), Nelfilcon A single vision contact lenses (DACP)
- Volunteers
- 24 people
- Sponsor
- Alcon Research
Myopia
One Month Dispensing Study Comparing the Clinical Performance of the Comfilcon A Sphere Lenses Compared to Comfilcon A Asphere Lenses.
This is a prospective, multi-center, subject-masked, bilateral wear, one month dispensing study comparing the clinical performance of the subjects' habitual comfilcon A sphere lens (control) following a refit with comfilcon A…
- Trial name
- NCT02759471
- Testing
- comfilcon A sphere lens (control), comfilcon A asphere lens (test)
- Where
- 4 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
Safety & Efficacy of Pilocarpine Eye Solutions for Temporary Improvement of Near Vision in Presbyopic Adults
Volunteer participants are evaluated for eligibility during a Screening Visit; those meeting study inclusion/exclusion criteria are scheduled for 3 treatment visits.
- Trial name
- VISION-1 (NCT04657172)
- Testing
- Pilocarpine Ophthalmic
- Where
- 9 sites in United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Eyenovia Inc.
Myopia
Evaluation of Daily Disposable Lenses With Multi-Purpose Solution (MPS)
The purpose of this study is to evaluate daily disposable lenses inserted out of the blister package versus daily disposable lenses inserted after a pre-soak in Multi-purpose solution FID 107027.
- Trial name
- NCT00733291
- Testing
- Nelfilcon A contact lens, Etafilcon A contact lens, FID 107027 solution
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Alcon Research
Refractive Errors, Accomodation
Study in Pediatric Volunteers of a Handheld Device Versus a Standard Diagnostic Device in Ophthalmic Refraction
This study is exploratory and examines whether the refraction results obtained from a novel optical device yields results similar to the ophthalmic refraction measurements obtained from an autorefractor in children.
- Conditions
- Refractive Errors, Accomodation, Diagnostic Self Evaluation
- Trial name
- NCT04955379
- Testing
- EQ103
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Astigmatism
Insertion Clinical Study to Evaluate the Orientation Characteristics of Multiple Kalifilcon A Daily Disposable Toric LD213001 Contact Lenses
The objective is to evaluate the fit characteristics (primary gaze orientation, rotational recovery, and movement) of kalifilcon A daily disposable toric lenses as compared to commercially available Ultra for Astigmatism lenses.
- Trial name
- NCT05129124
- Testing
- kalifilcon A Daily Disposable Toric LD213001 Contact Lenses, Commercially available Ultra for Astigmatism Contact Lenses
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Clinical Assessment of Two Daily Wear Monthly Replacement Soft Silicone Hydrogel Contact Lenses
The purpose of this study is to compare the clinical performance of TOTAL30 contact lenses with Biofinity contact lenses over 30 days of daily wear.
- Trial name
- NCT04980456
- Testing
- Lehfilcon A contact lenses, Comfilcon A contact lenses, CLEAR CARE
- Where
- 14 sites in United States
- Volunteers
- 257 people
- Sponsor
- Alcon Research
Astigmatism
Prospective Evaluation of the Long-term Effectiveness of the Femtosecond Laser-assisted Arcuate Incisions
This clinical study is an open, controlled, prospective, single center, single-surgeon, post-market-clinical-follow-up study to evaluate the long-term (18 months) effectiveness of the femtolaser-assisted astigmatic keratotomy.
- Trial name
- NCT02164994
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technolas Perfect Vision GmbH
Hyperopia
Safety and Effectiveness of Wavefront-Guided LASIK Correction of Hyperopic Refractive Errors
Demonstrate that wavefront-guided LASIK using measurements from the iDesign System is safe and effective for the treatment of Hyperopia.
- Trial name
- NCT01675479
- Testing
- LASIK correction of hyperopic refractive errors
- Where
- 9 sites in United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Refractive Errors
Clinical Comparison of Two Daily Disposable Contact Lenses
The purpose of this study is to compare the clinical performance of PRECISION1™ contact lenses to Clariti® 1 day contact lenses.
- Trial name
- NCT04865354
- Testing
- Verofilcon A contact lenses, Somofilcon A contact lenses
- Where
- 8 sites in United States
- Volunteers
- 170 people
- Sponsor
- Alcon Research