Clinical trials: Eye--Refractive Errors
Myopia
Comparison of Efficacy Between Two Myopia Control Lenses
This is a one-year, mono-centre, randomize, double-masked, monocular cross-over clinical trial designed to test and compare the efficacy of the new lens design in slowing down the increase of axial length and controlling myopia…
- Trial name
- NCT06148870
- Testing
- Myopia Control Lens-1 (MCL1), Myopia Control Lens-2 (MCL2)
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia
Clinical Performance of Stenfilcon A Versus Filcon II 3
Clinical Performance of Stenfilcon vs. Filcon II 3
- Trial name
- NCT01808209
- Testing
- stenfilcon A, filcon II 3
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Refractive Errors
Safety and Effectiveness of the Qualis Contact Lens
Three-month, open-label, bilateral, parallel group, randomized, daily wear contact lens dispensing study.
- Trial name
- NCT04295499
- Testing
- soft (hydrophilic) contact lens
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Unicon Optical Co. Ltd.
Myopia
Pilot Evaluation of a New Galyfilcon A Lens Prototype and Enfilcon A Lens
The purpose of this study is to compare the visual acuity, limbal and bulbar redness of the new galyfilcon A prototype lenses against Avaira® lenses when worn as daily wear for seven (7) days.
- Trial name
- NCT01192542
- Testing
- galyfilcon A prototype lens, enfilcon A lens
- Where
- 3 sites in United States
- Volunteers
- 39 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Study to Evaluate the Safety and Efficacy of Eye Secret UV Aspheric Silicone Soft (Hydrophilic) 1Day Color Contact Lens
This was a prospective, randomized, open label, parallel, active-controlled clinical study to assess the safety and efficacy of Silicone Color Contact Lens for vision correction.
- Trial name
- NCT06527586
- Testing
- soft contact lens
- Where
- 3 sites in Taiwan
- Volunteers
- 131 people
- Sponsor
- Yung Sheng Optical Co., Ltd.
Presbyopia
A Feasibility Study to Assess the Visual Performance and Comfort of Hanita G4 Multifocal Soft Contact Lenses for Presbyopia at Normal Daily Routine Use
The G4 Multi multifocal contact lens is a soft contact lens intended to correct far, intermediate, and near vision for individuals with presbyopia. The lens covers the cornea and part of the sclera.
- Trial name
- NCT04841941
- Testing
- G4 Multifocal soft contact lens with a 54% water content for presbyopia
- Where
- 2 sites in Israel
- Volunteers
- 25 people
- Sponsor
- Hanita Lenses
Myopia
CHAMP: Study of NVK-002 in Children With Myopia
Stage 1: To evaluate the safety and efficacy of 2 concentrations of NVK-002 compared to Vehicle (placebo) for slowing the progression of myopia in children over a 3 year treatment period.
- Trial name
- NCT03350620
- Testing
- NVK-002 Concentration 1, NVK-002 Concentration 2
- Where
- 26 sites in United States, Hungary and 4 more
- Volunteers
- 670 people
- Sponsor
- Vyluma, Inc.
Myopia
Influence of Rodenstock Spectacle Lenses on Myopia Progression.
The prevalence of myopia in Singapore is among the highest in the world, with 65 percent of our children being myopic by Primary 6, and 83 percent of young adults being myopic.
- Trial name
- NCT06816446
- Testing
- Myopia control spectacle lens, Single-vision lens
- Where
- Singapore
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Rodenstock GmbH
Myopia
Daily Disposable Contact Lens Tear Film Study
The purpose of this study was to evaluate the pre-lens tear film stability of a new CE-marked daily disposable contact lens as compared to a commercially available daily disposable contact lens.
- Trial name
- NCT01473160
- Testing
- delefilcon A contact lens, narafilcon A contact lens
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- CIBA VISION
Myopia
Evaluation of Stenfilcon A Versus Etafilcon A
Evaluation of two contact lenses
- Trial name
- NCT01809834
- Testing
- Etafilcon A, Stenfilcon A
- Where
- Canada
- Volunteers
- 46 people
- Sponsor
- CooperVision, Inc.
Refractive Errors
Clinical Performance of Two Reusable Silicone Hydrogel Contact Lenses
The purpose of this study is to assess the clinical performance of two reusable silicone hydrogel contact lenses when worn on a daily wear basis.
- Trial name
- NCT05431478
- Testing
- Serafilcon A contact lenses, Senofilcon A contact lenses, CLEAR CARE
- Where
- 5 sites in United States
- Volunteers
- 68 people
- Sponsor
- Alcon Research
Myopia
Evaluation of Two Different Designs of Bausch & Lomb Contact Lenses
The objective of this one month study is to evaluate the product performance of a redesigned PureVision Contact Lens compared to the PureVision Contact Lens when worn on a daily wear basis by wearers of contact lenses.
- Trial name
- NCT01118338
- Testing
- Redesigned Purevision Contact Lens, PureVision Contact Lens
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- Bausch & Lomb Incorporated
Myopia
Four Week Performance Comparison Between Two Commercially Available Silicone Hydrogel Lenses
The purpose of this study is to compare the performance of two commercially marketed contact lenses when worn for up to 4 weeks in a daily wear modality.
- Trial name
- NCT01300767
- Testing
- Lotrafilcon B contact lens (AIR OPTIX® AQUA), Balafilcon A contact lens (PureVision® 2), Contact lens solution (Clear Care®)
- Volunteers
- 75 people
- Sponsor
- CIBA VISION
Myopia
Exploratory Study on the Effectiveness of Myopia Control Lenses in Slowing Myopia Progression in Young Children
This study will be a mono-center, single-arm, unmasked study evaluating the effectiveness of test lens in slowing myopia progression in children aged 6 to 8 years.
- Trial name
- NCT06857864
- Testing
- Test myopia control lenses (BSL)
- Where
- Singapore
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Essilor International
Refractive Errors
Apioc Toric/Spherical Single Vision Contact Lens
The Lentechs Apioc-S and Apioc-A contact lenses are made in an FDA-approved contact lens material indicated for single-vision and astigmatism.
- Trial name
- NCT03970512
- Testing
- Apioc-A and Apioc-S Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Lentechs, LLC
Myopia
Clinical Performance of Hydrogel vs. Silicone Hydrogel Contact Lenses
The aim of this non-dispensing fitting study is to evaluate the subjective comfort, lens handling, lens fitting characteristics and visual acuity of different hydrogel lens designs versus silicone hydrogel lenses
- Trial name
- NCT02131402
- Testing
- ocufilcon D, omafilcon A, methafilcon A
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- CooperVision, Inc.
Astigmatism, Myopia
Evaluation of Two Daily Disposable Contact Lenses for Wearers With Astigmatism
The purpose of this trial is to compare the performance of two contact lenses for contact lens wearers with astigmatism.
- Trial name
- NCT01207466
- Testing
- Nelfilcon A investigational contact lens, Nelfilcon A commercial contact lens
- Volunteers
- 95 people
- Sponsor
- CIBA VISION
Myopia, Hyperopia
Daily Disposable Performance of 1•DAY ACUVUE® TruEye™ and 1•DAY ACUVUE® MOIST® With LACREON® TECHNOLOGY
This study is an observational registry of patients who have recently been prescribed 1•DAY ACUVUE® TruEye® or 1•DAY ACUVUE® MOIST® Brand Contact Lenses with LACREON® TECHNOLOGY.
- Trial name
- TEMPO (NCT01467557)
- Testing
- narafilcon B daily disposable soft contact lenses, etafilcon A daily disposable soft contact lenses
- Where
- 37 sites in United States
- Volunteers
- 1,171 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Cornea
Euclid Phoenix Lens Design Trial 2
Lens wettability and subjective comfort of Euclid orthokeratology lenses with and without an enhanced coating will be compared in 50 children. Axial elongation will be monitored in pediatric patients who qualify and consent.
- Trial name
- NCT06392607
- Testing
- Euclid orthokeratology (standard coating), Euclid orthokeratology (enhanced coating)
- Where
- 5 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Euclid Systems Corporation
Myopia
Non-dispense Comfort Comparison of Two Silicone Hydrogel Lenses
The purpose of this study is to compare subjective responses to two contact lenses after 15 minutes of wear.
- Trial name
- NCT00808834
- Testing
- Lotrafilcon A contact lens, Senofilcon A contact lens
- Volunteers
- 196 people
- Sponsor
- CIBA VISION