Clinical trials: Eye--Refractive Errors
Myopia, Progressive, Children, Only
Myopia Control With Orthokeratology Contact Lenses in Spain
The purpose of this prospective study is to assess the efficacy, safety and patient-reported outcomes of the Menicon Z Night orthokeratolgy contact lens for reducing myopia progression in children.
- Conditions
- Myopia, Progressive, Children, Only, Contact Lens Complication, Perception, Self
- Trial name
- MCOS (NCT04806763)
- Testing
- Menicon Z Night, Control
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Presbyopia
An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-1)
This is a 4-visit, multi-center, randomized, double-masked, vehicle-controlled study evaluating the safety and efficacy of CSF-1 in the temporary correction of presbyopia.
- Trial name
- NEAR-1 (NCT04599933)
- Testing
- CSF-1, Vehicle
- Where
- 17 sites in United States
- Volunteers
- 309 people
- Sponsor
- Orasis Pharmaceuticals Ltd.
Aphakia, Presbyopia
Real-World Study of Vivity Intraocular Lenses (IOLs)
The primary objective of this clinical study is to assess the clinical performance of the AcrySof IQ Vivity Extended Vision IOL in a Chinese population.
- Trial name
- NCT04800016
- Testing
- AcrySof IQ Vivity Extended Vision IOL, Cataract surgery
- Where
- China
- Sponsor
- Alcon Research
Myopia
To Evaluate The Performance Of Two Monthly Replacement Silicone Hydrogel Contact Lenses After 1-month Of Wear
To evaluate the performance of two monthly replacement silicone hydrogel contact lenses in habitual FRP CL wearers when worn for 1-month.
- Trial name
- NCT05333965
- Testing
- Lens A (lehfilcon A lens), Lens B (comfilcon A lens)
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Astigmatism, Presbyopia
North American Comfilcon A Clinical Study
The main objective of this study is to demonstrate acceptable safety and effectiveness (performance) of comfilcon A Sphere, Toric, Multifocal, Toric Multifocal and Energys lenses, when used in the general population.
- Conditions
- Astigmatism, Presbyopia, Ametropia
- Trial name
- NCT06902584
- Testing
- comfilcon A Sphere lens, comfilcon A Toric lens, comfilcon A Multifocal lens
- Where
- 4 sites in United States
- Volunteers
- 182 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia
Evaluation of Lotrafilcon A Lenses Over a Three Month Period
The purpose of this trial is to assess the performance of a Lotrafilcon A contact lens over a 3-month period.
- Trial name
- NCT00931307
- Testing
- Lotrafilcon A contact lens
- Volunteers
- 22 people
- Sponsor
- CIBA VISION
Myopia
Evaluation of Deposits on Contact Lenses Worn Extended Wear
The purpose of this study was to measure lipid deposits on commercially marketed contact lenses when worn on an extended wear (overnight) basis for 7 days.
- Trial name
- NCT00725530
- Testing
- balafilcon A contact lens (PureVision), etafilcon A contact lens (Acuvue2)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Alcon Research
Myopia
Subjective Evaluation of a Commercially Marketed Contact Lens Amongst a Subset of the Contact Lens Wearing Population
The purpose of this study is to compare the performance of commercially marketed contact lenses to habitual contact lenses in a selected segment of the contact lens wearing population.
- Trial name
- NCT01007916
- Testing
- Lotrafilcon B contact lens, Habitual contact lens
- Volunteers
- 50 people
- Sponsor
- CIBA VISION
Myopia, Astigmatism
Multicenter Dispensing Study of Biofinity Toric Made-To-Order Lenses in Extended Power Ranges
The study hypothesis is that the Biofinity Toric XR lenses will perform as well as or better than the participants' habitual contact lenses.
- Trial name
- NCT02193178
- Testing
- comfilcon A Toric
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- CooperVision, Inc.
Myopia, Astigmatism
A Safety and Effectiveness Study of PRK Using the ALLEGRETTO WAVE® EYE-Q Excimer Laser System
The purpose of this study is to evaluate the safety and effectiveness of the ALLEGRETTO WAVE EYE-Q excimer laser system for the reduction of myopia with or without astigmatism in subjects undergoing photorefractive keratectomy…
- Trial name
- NCT01699087
- Testing
- Photorefractive keratectomy (PRK), ALLEGRETTO WAVE EYE-Q excimer laser system
- Volunteers
- 176 people
- Sponsor
- Alcon Research
Refractive Error
WaveLight® Refractive Myopic Study
The purpose of this study is to evaluate outcomes of subjects undergoing myopic surgery using the WaveLight® Refractive Suite (Excimer EX500 and Femtosecond FS200 lasers).
- Trial name
- NCT01941498
- Testing
- Wavelight® Refractive Suite, LASIK surgery
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Daily Disposable Toric Comparative Trial in Europe
The purpose of this study is to investigate the subjective and objective performance of two daily disposable lenses for wearers with astigmatism.
- Trial name
- NCT01070381
- Testing
- nelfilcon A contact lens, ocufilcon D contact lens
- Volunteers
- 220 people
- Sponsor
- CIBA VISION
Cataract, Presbyopia
Evaluation of Visual Outcomes in Patients With Complex Corneas Implanted With the IC-8 IOL
The purpose of this study is to evaluate visual outcomes in patients with complex corneas who have been previously implanted with the IC-8 IOL after cataract removal.
- Conditions
- Cataract, Presbyopia, Irregular; Contour of Cornea
- Trial name
- NCT05377515
- Where
- Singapore
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Presbyopia
Study of AGN-190584 Eye Drops to Assess Safety and Efficacy in Participants Aged 40-80 Years With Pseudophakic Presbyopia
Presbyopia is a condition in which the eye exhibits a diminished ability to focus on near objects with increasing age. This study will assess the safety and exploratory efficacy of AGN-190584 is in treating participants with…
- Trial name
- ARIES (NCT05393089)
- Testing
- AGN-190584, Vehicle
- Where
- 32 sites in United States
- Sponsor
- Allergan
Myopia
Projected Peripheral Defocus Using a Wearable Device
Acucela Inc. intends to develop a medical device to significantly halt or reverse myopic progression, which is a significant public health concern across the world, especially in Asian demographics.
- Trial name
- NCT04415684
- Testing
- Active projection of defocused image in the peripheral visual field (eSpecs, Acucela Inc.), No Active projection of defocused image in the peripheral visual field (eSpecs, Acucela Inc.)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Kubota Vision Inc.
Myopia
Evaluation of the Efficacy in Decreasing Myopia Progression of the Proposed Ophthalmic Lens Prototypes
Evaluation of the efficacy in decreasing myopia progression of the proposed ophthalmic lens prototypes.
- Trial name
- NCT05250206
- Testing
- Myopia control lens
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Indizen Optical Technologies, S.L.U.
Myopia
Clinical Comparison of Two Daily Disposable Contact Lenses in a Population of Daily Disposable Contact Lens Wearers
The purpose of this study is to evaluate the performance of two commercially marketed daily disposable contact lenses in a population of daily disposable contact lens wearers.
- Trial name
- NCT01233076
- Testing
- Nelfilcon A contact lens, Narafilcon B contact lens
- Volunteers
- 60 people
- Sponsor
- CIBA VISION
Refractive Errors, Myopia
Performance Assessment of a Modified Daily Disposable Contact Lens
The purpose of this study is to compare visual acuity between two daily disposable contact lenses.
- Conditions
- Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT03762668
- Testing
- Modified delefilcon A contact lenses, Delefilcon A contact lenses
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Alcon Research
Myopia
A Dispensing Clinical Trial of Test Contact Lens Against Marketed Contact Lens
Evaluation of the clinical performance of an investigational silicone-hydrogel contact lens (test) compared to a marketed lens (control), when worn on a daily basis for 1 month.
- Trial name
- NCT03499067
- Testing
- Test lens, Control lens
- Where
- 2 sites in United States
- Volunteers
- 58 people
- Sponsor
- CooperVision, Inc.
Ametropia
Safety and Efficacy of a New Transepithelial Photorefractive Keratectomy Treatment
This is a prospective, comparative, randomized, controlled, single-blind, single-surgeon, single-center PMCF clinical study whereby participants undergoing refractive surgery for correction of ametropia will receive a…
- Trial name
- NCT04698174
- Testing
- Transepithelial Photorefractive keratectomy (tPRK) without laser polishing, Transepithelial Photorefractive keratectomy (tPRK) with laser polishing, Standard Photorefractive keratectomy (PRK)
- Where
- Philippines
- Volunteers
- 39 people
- Sponsor
- Bausch & Lomb Incorporated