Clinical trials: Eye--Refractive Errors
Cataract, Refractive Error
Community-Based Eye Screening With Structured Referral Tracking for Preventing Avoidable Blindness in Adults in Rawalpindi, Pakistan
This cluster randomized controlled trial aims to evaluate the effectiveness of a Structured Referral Tracking (SRT) intervention in improving referral completion among adults identified with avoidable blindness during…
- Conditions
- Cataract, Refractive Error, Diabetic Retinopathy
- Trial name
- SIGHT (NCT07611682)
- Testing
- Structured Referral Tracking (SRT)
- Where
- Pakistan
- Volunteers
- 500 people
- Sponsor
- Health Services Academy, Islamabad, Pakistan
Myopia
1 Week Crossover Study Between Two Soft Contact Lenses
The objective of this investigation is to compare the visual clinical performance of two daily disposable soft contact lenses.
- Trial name
- NCT06611410
- Testing
- Test Lenses (stenfilcon A), Control Lenses (omafilcon A)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Clinical Outcomes of Femtosecond Laser Presbyopia Treatment in Monofocal IOLs
This study aimed to assess the safety and efficacy of treating presbyopia in eyes implanted with a mono focal IOL using a low-energy femtosecond laser.
- Trial name
- NCT07384182
- Testing
- Perfector
- Where
- Czechia
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Perfect Lens, LLC
Astigmatism
Clinical Performance of Atypical Contact Lens Powers on Subjects With Astigmatism
This study will evaluate the fitting characteristics and physiological response of two toric lenses manufactured by Vistakon.
- Trial name
- NCT00697190
- Testing
- senofilcon A toric, galyfilcon A toric
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia, Progressive
Atropine 0.01% Eye Drops in Myopia Study
Control of myopia progression has become an important goal because of concerns regarding significantly increased risks of retinal degeneration, retinal detachment, glaucoma and cataract associated with high myopia.
- Trial name
- AIMS (NCT03508817)
- Testing
- Atropine Sulfate 0.01% Eye Drops
- Where
- Oman
- Volunteers
- 150 people
- Sponsor
- Sultan Qaboos University
Myopia
Dehydration of Stenfilcon A Contact Lenses Versus Delefilcon A Contact Lenses
The study will explore in vivo lens dehydration rates across a 12hr wear period for the study lenses.
- Trial name
- NCT02366923
- Testing
- stenfilcon A, delefilcon A
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- CooperVision, Inc.
Ametropia
Safety and Efficacy of Different Add Powers With a New Presbyopic Lasik Treatment Algorithm
This is a prospective, comparative, randomized, controlled, open-label, single-surgeon, single-center PMCF clinical study whereby presbyopic patients undergoing refractive surgery will receive a SUPRACOR treatment for the…
- Trial name
- NCT04617080
- Testing
- SUPRACOR Regular, SUPRACOR Strong
- Where
- Philippines
- Volunteers
- 60 people
- Sponsor
- Bausch & Lomb Incorporated
Refractive Error, Myopia
Clinical Performance of a New Daily Disposable Contact Lens Worn in a Neophyte Population.
This study seeks to evaluate the impact of wearing a new daily disposable soft contact lens on the neophyte population.
- Trial name
- NCT00708032
- Testing
- spectacles, narafilcon A soft contact lenses
- Where
- United Kingdom
- Volunteers
- 74 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Pathologic Myopia
LED Red Light in Modulating Choroidal Microcirculation to Retard Retinal Atrophy in Pathological Myopia
The goal of this clinical trial is to learn if LED repeated low-level red light (RLRL) therapy works to treat pathologic myopia in adults. It will also learn about the safety of LED-RLRL.
- Trial name
- NCT07312214
- Testing
- LED red light
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Corneal Astigmatism
Tomographic Analysis of Anterior, Posterior, Total Corneal Refractive Power Changes After Laser-assisted Keratotomy
To analyze the effect of femtolaser-assisted keratotomy on corneal astigmatism (anterior, posterior and Total corneal refractive power) measured by Scheimpflug tomography after laser lens surgery.
- Trial name
- NCT03097302
- Testing
- Laser keratotomy
- Volunteers
- 23 people
- Sponsor
- University Clinic Frankfurt
Myopia, Hyperopia
Comparing Low-cost Handheld Autorefractors - a Practical Approach to Measuring Refraction in Low Resource Settings
Study compares four portable vision measurement and eye-imaging technologies in terms of accuracy and time and ease of use with older adult (ages 40-100) participants in a developing-country setting (India).
- Trial name
- NCT03456245
- Testing
- Vision device validation
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Myopia
Dual Focus Soft Contact Lens Wear Cessation Study
The purpose of this study is to investigate the effect of ceasing treatment with dual focus soft contact lenses.
- Trial name
- NCT05779072
- Testing
- Single Vision Soft Contact Lens
- Where
- 4 sites in Canada, Portugal and 2 more
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Refractive Errors
Patients' Satisfaction After LASIK
The aim of this study is to evaluate the level of satisfaction, functional vision and quality of life outcome of patients after LASIK surgery.
- Trial name
- NCT04109040
- Testing
- slit lamp
- Volunteers
- 50 people
- Sponsor
- Assiut University
Myopia
Effects of Contact Lens Care Regimens on the Corneal Epithelium
The purpose of this study is to compare the performance of two different contact lens care solutions, specifically their affects on the front surface of the eye.
- Trial name
- NCT00349882
- Testing
- soft contact lens, Marketed multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Waterloo
Myopia, Astigmatism
Comparative In-Vivo Wetting Characteristics of Silicone Hydrogel Materials With Selected Lens Care Systems
The purpose of this study is to evaluate the lipid uptake, wetting characteristics, and visual performance of AIR OPTIX® AQUA and ACUVUE® OASYS® with HYDRACLEAR® contact lenses when used in conjunction with two contact lens care…
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01699750
- Testing
- Lotrafilcon B contact lenses, Senofilcon A contact lenses, OPTI-FREE® PUREMOIST® MPDS
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- Alcon Research
Myopia
Influence of Rodenstock Spectacle Lenses on Myopia Progression.
The prevalence of myopia in Singapore is among the highest in the world, with 65 percent of our children being myopic by Primary 6, and 83 percent of young adults being myopic.
- Trial name
- NCT06816446
- Testing
- Myopia control spectacle lens, Single-vision lens
- Where
- Singapore
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Rodenstock GmbH
Myopia, Corneal Crosslinking
Advanced Cross Linking for Low-grade Myopia
To evaluate the improvement in myopic refractive error and the corneal endothelial safety with a corneal crosslinking treatment regimen for mild myopia.
- Trial name
- PiXLO2 (NCT03197272)
- Testing
- PiXL
- Where
- Sweden
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Umeå University
Disorders, Refractive
A Comparison of Two Devices for Measuring the Central Thickness of the Cornea Before and After Surgery (CECOT)
Corneal topography allows the measure of the radii of curvature and of the thickness of the cornea. It is essential for diagnosis in ophthalmology and allows to highlight corneal irregularities such as a keratoconus, or too thin…
- Trial name
- CECOT (NCT02522416)
- Testing
- Central corneal thickness measurement
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Myopia, Progressive
DIMS-myopia Progression ADN Axial Length Growth
To confirm the efficacy of DIMS lenses in controlling myopia progression, we planned a prospective randomized controlled clinical study.
- Trial name
- NCT05300321
- Testing
- frame lens
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Myopia
Vistakon Investigational Contact Lenses Worn for Daily Wear
This study compares the performance of an investigational contact lens to a currently marketed lens.
- Trial name
- NCT00717249
- Testing
- galyifilcon A control lens, galyfilcon A with a silver additive
- Where
- 20 sites in United States
- Volunteers
- 529 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
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