Clinical trials: Eye--Refractive Errors
Myopia
Investigation of Wearing Compliance of Spectacles for Myopia Control
The goal of this observational study was to compare the wearing patterns of spectacles prescribed for myopia control in juvenile wearers.
- Trial name
- NCT06590441
- Testing
- Myopia control spectacles
- Where
- 4 sites in United Kingdom
- Volunteers
- 53 people
- Sponsor
- CooperVision, Inc.
Myopia
Myopia Control in Children: Comparison of Defocus Incorporated Multiple Segments® Lenses Versus Atropine 0.05% Eyedrops
Myopia is the most common refractive disorder in the world. Many strategies have been developed to control myopia in children. Among them, the instillation of low-concentration atropine eyedrops has been proven to be effective in…
- Trial name
- ATROSMART (NCT05062031)
- Testing
- Defocus Incorporated Multiple Segments® (DIMS®) lenses, Atropine 0.05% eyedrops, Monofocal lenses
- Where
- France
- Volunteers
- 116 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Glaucoma, Cataract
Vivity Outcomes in Patients With Early Stage Glaucoma
The goal of the study is to determine the visual outcomes in patients with mild, pre-perimetric glaucoma who undergo cataract surgery with implantation of the Alcon Vivity Extended Range Intraocular Lens (IOL).
- Conditions
- Glaucoma, Cataract, Presbyopia
- Trial name
- VIVA (NCT04670575)
- Testing
- Cataract Surgery with Implantation of Vivity Extended Range of Vision IOL
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vance Thompson Vision
Astigmatism
Effect of Eye Movement on Toric Lens Orientation and Visual Acuity
The relative performance of a new toric soft contact lens against toric contact lenses currently available in market, specifically for visual acuity and lens orientation.
- Trial name
- NCT00584831
- Testing
- senofilcon A, balafilcon A, omafilcon A
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Corneal Astigmatism
Tomographic Analysis of Anterior, Posterior, Total Corneal Refractive Power Changes After Laser-assisted Keratotomy
To analyze the effect of femtolaser-assisted keratotomy on corneal astigmatism (anterior, posterior and Total corneal refractive power) measured by Scheimpflug tomography after laser lens surgery.
- Trial name
- NCT03097302
- Testing
- Laser keratotomy
- Volunteers
- 23 people
- Sponsor
- University Clinic Frankfurt
Axial Length, Eye, Myopia
Study on the Impact of Desk and Chair Adaptation Intervention on the Occurrence and Development of Myopia in Primary School Students
This study is a randomized controlled trial of a desk and chair adaptation intervention involving primary school students and their parents or primary caregivers.
- Conditions
- Axial Length, Eye, Myopia, Myopia Progression
- Trial name
- NCT06623760
- Testing
- Desk and chair adaptation interventions
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Fangbiao Tao
Astigmatism
Clinical Performance of Habitual Wearers of Avaira Toric When Refitted With Clariti Toric Lenses
The aim of this dispensing study is to evaluate the clinical performance of existing wearers of Avaira toric lenses following a refit with Clariti toric over 1 month of daily wear.
- Trial name
- NCT02248766
- Testing
- somofilcon A
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Assessment of Near Vision Capacity in Different Light Intensities
Patients who underwent presbyopic correction with bilateral bifocal intraocular lenses implantation are supposed to have sufficient uncorrected vision capacity for activities of daily living (ADLs) that require near vision acuity…
- Trial name
- NCT03024073
- Testing
- BB-Phaco
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Democritus University of Thrace
Near Vision
Evaluation of Near Visual Acuity With ODYSIGHT, a Smartphone Based Medical App in Comparison to a Standardized Method
This study evaluates the level of agreement between visual parameters tested using OdySight, a mobile application, and standards in office methods.
- Trial name
- TIL-001 (NCT03457441)
- Testing
- Standards vision tests, OdySight medical application assessment
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tilak Healthcare
Myopia
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
Effects on Ocular Parameters of Myopic Eyes After Orthokeratology in Myopic Children
- Trial name
- NCT03516357
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia
Performance of Somofilcon A Over One Week in Wearers Adapted to Omafilcon A
The objective of the study is to determine if habitual or adapted contact lens wearers of Omafilcon A can be confidently refit into Somofilcon A lenses and be successful after one week of daily wear.
- Trial name
- NCT03226353
- Testing
- somofilcon A, omafilcon A
- Where
- Canada
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Presbyopia
A Clinical Trial to Evaluate the Safety and Effectiveness of the Raindrop Near Vision Inlay for Pseudophakic Subjects
The objective of this study is to evaluate the safety and effectiveness of the Raindrop Near Vision Inlay implanted in bilateral pseudophakes with presbyopia for improvement of near and intermediate vision.
- Trial name
- NCT03017612
- Testing
- Raindrop Near Vision Inlay
- Where
- 6 sites in United States
- Volunteers
- 13 people
- Sponsor
- ReVision Optics, Inc.
Myopia, Astigmatism
SMILE vs. LASIK Using Contoura With Phorcides
Subjects will undergo SMILE surgery in one eye and LASIK using Contoura with Phorcides on the contralateral eye to correct myopia.
- Trial name
- NCT05844397
- Testing
- WaveLight EX500 Excimer Laser System, VisuMax Surgical Laser
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- 59th Medical Wing
Myopia
Lens Fitting Evaluation of CooperVision MyDay™ Compared With 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®
Lens Fitting Evaluation of CooperVision MyDay™ Compared with 1-DAY ACUVUE® TruEye® and DAILIES TOTAL1®
- Trial name
- NCT02341859
- Testing
- stenfilcon A, delefilcon A, narafilcon A
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- CooperVision, Inc.
Ametropia
Contact Lens Wettability
The purpose of this study is to compare the wettability of contact lenses disinfected with three marketed contact lens care solutions.
- Trial name
- NCT00349063
- Testing
- soft contact lens, Soft contact lens multipurpose disinfection regimen
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University of Waterloo
Myopia
Evaluation of a New Silicone Hydrogel Contact Lens
The objective of this study is to determine the clinical feasibility and to evaluate the product performance of investigational contact lenses developed by Bausch + Lomb.
- Trial name
- NCT01309880
- Testing
- Test lens, Air Optix Aqua
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Myopia, Progressive
Crossover RCT of TAMER Lenses in Myopia Control
This study is a prospective, randomized, crossover clinical trial with a planned proposed enrollment of 120 Chinese male and female subjects aged 6-12 years without systemic or ocular diseases to follow up their cycloplegic…
- Trial name
- NCT06329986
- Testing
- TAMER Lens Spectacle, SV lenses
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Emmetropization, Myopia
Focus-out Glasses on Emmetropization in Chinese Children
The purpose of this study is to characterize the effects of peripheral focous-out glasses on emmetropization in non-myopic Chinese Children Aged 6-8 Years.This is a prospective, parallel-controlled randomized trial.
- Conditions
- Emmetropization, Myopia, Hyperopia
- Trial name
- NCT05689567
- Testing
- DEFOG glasses(peripheral focus-out glasses)
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Myopia
A Phase III Clinical Study of the Efficacy and Safety of Two Low-concentration Atropine Sulfate Eye Drops
This study was a randomized, double-blind, placebo-controlled, multicenter, superiority design, phase III clinical trial to compare the efficacy and safety of two low-concentration atropine sulfate eye drops versus placebo in…
- Trial name
- Mini-CHAMP (NCT06209281)
- Testing
- Lower dose atropine sulfate eye drops, Low dose atropine sulfate eye drops
- Where
- China
- Volunteers
- 526 people
- Sponsor
- Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.
Posterior Chamber Phakic Intraocular Lens, Vault
Study on the Diagnostic Efficacy of ICL Selection and Prediction Depth Model Based on Eye Images
To evaluate the diagnostic efficacy of deep learning network model in implantable collamer lens selection and prediction in a multicenter cross-sectional study
- Conditions
- Posterior Chamber Phakic Intraocular Lens, Vault, Deep Neural Network, Myopia
- Trial name
- NCT06669728
- Testing
- AI diagnostic algorithm
- Where
- China
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Nanchang University
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