Clinical trials: Eye--Refractive Errors
Astigmatism
Comparison of Senofilcon A Toric Lenses to Balafilcon A Toric Lenses Over Extended Wear Period
To evaluate two toric contact lenses on the ocular physiology of existing contact lens wearers when used in an extended wear modality of days/six nights.
- Trial name
- NCT00762502
- Testing
- senofilcon A toric contact lens, balafilcon A toric contact lens
- Where
- 8 sites in United States, Australia
- Volunteers
- 112 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Myopia
A Comparison of Manufacturing Processes for AIR OPTIX® COLORS Contact Lens
The purpose of this feasibility study was to compare AIR OPTIX® COLORS contact lenses manufactured using an automated process to AIR OPTIX® COLORS contact lenses manufactured using a semi-automatic process.
- Trial name
- NCT01614678
- Testing
- Lotrafilcon B contact lens with color, automated, Lotrafilcon B contact lens with color, semi-automated
- Volunteers
- 49 people
- Sponsor
- CIBA VISION
Presbyopia, Pseudophakia
Identification of Minimum Focal Points in Vision Curve Formation
The primary objective of this study is to identify how many focal points and at which distances are necessary for reliable visual curve formation and area of the curve (AoC) calculation using mathematical models and comparing the…
- Conditions
- Presbyopia, Pseudophakia, Cataract, Refractive Errors
- Trial name
- NCT06260852
- Testing
- Diagnostic Test: Visual Acuity Assessment
- Where
- Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Democritus University of Thrace
Glaucoma, Diabetic Retinopathy
Providing Financial Incentives to Improve Adherence to Referral Eye Care Visits
Glaucoma is a blinding eye disease increasingly common in older adults, particularly in African Americans, and often diagnosed late in the disease course.
- Conditions
- Glaucoma, Diabetic Retinopathy, Refractive Errors, Cataract
- Trial name
- AL-SIGHT (NCT04328207)
- Testing
- No Financial Incentive, Financial Incentive
- Where
- United States
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Refractive Errors
Study to Evaluate the Safety and Efficacy of HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
Study to evaluate the safety and efficacy of HI-BRITE large diameter rigid gas permeable contact lens (hexafocon b) test when worn on a daily wear basis in the correction of myopia/hyperopia/astigmatism/presbyopia/ and irregular…
- Trial name
- NCT02812316
- Testing
- HI-BRITE Large Diameter Rigid Gas Permeable Contact Lens
- Where
- Taiwan
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Hospital
Myopia
Short-term Clinical Performance of Multifocal Soft Contact Lens
The study is aimed to observe the short-term clinical performance of MiSight™ multifocal soft contact lens compared with Proclear™ 1day, including objective examination, subjective acceptability of wearers, and doctors'…
- Trial name
- NCT05273606
- Testing
- MiSight mutifocal soft contact lens, Proclear 1 Day soft contact lens
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Astigmatism
Corneal Astigmatism Measurement Study
To assess which commercially available measurement device is most accurate in measuring low (< 1.0 D) degrees of corneal astigmatism.
- Trial name
- NCT00818532
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Refraction Error, Myopia
The MORE Study: Manifest vs. Online Refraction Evaluation
The assessment of the refractive state of the eye is a fundamental and important part of ophthalmic and optometric clinical practice.
- Conditions
- Refraction Error, Myopia, Astigmatism
- Trial name
- MORE (NCT03313921)
- Testing
- Online Manifest Refraction
- Where
- Netherlands
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Cataract, Presbyopia
Clinical Investigation of the Visual Outcomes and Safety of a Trifocal Intraocular Lens (IOL) in a Korean Population
The purpose of this study is to confirm the effectiveness of the investigational lens in a Korean population, especially for visual performance, quality of vision, and subject satisfaction with the visual outcome, as well as the…
- Trial name
- NCT03268746
- Testing
- AcrySof IQ PanOptix Multifocal IOL
- Where
- 4 sites in South Korea
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Myopia
650nm Low-level Red-light for Myopia Control and Prevention in Children
A multicenter randomized controlled trial, evaluating the efficacy and safety of 650nm low-level red-light irradiation for myopia control and prevention in children.
- Trial name
- NCT05786586
- Testing
- 650 nm low-level red-light
- Where
- China
- Volunteers
- 572 people
- Sponsor
- Beijing Tongren Hospital
Cataract, Corneal Astigmatism
Comparison of Toric IOL Implantation and Opposite Clear Corneal Incision During Cataract Surgery to Correct Corneal Astigmatism
With increasing demands of patients concerning refractive outcome after cataract surgery, toric intraocular lenses (IOLs) that correct corneal astigmatism have been introduced more widely to cataract surgery.
- Trial name
- NCT01763151
- Testing
- toric IOL, IOL combined with opposite clear corneal incision (OCCI)
- Where
- Austria
- Volunteers
- 55 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Presbyopia
Safety and Effectiveness Study of the AcuFocus Corneal Inlay ACI 7000PDT in Presbyopes
The purpose of this study is to determine if the AcuFocus Corneal Inlay ACI 7000PDT will provide an effective method for the correction of presbyopia in patients who have normal distance vision but need a correction such as…
- Trial name
- ACI (NCT00850031)
- Testing
- AcuFocus Corneal Inlay
- Where
- 8 sites in Australia, Austria and 4 more
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Cataract, Lens Opacities
Clinical Investigation of a Monofocal Toric Intra Ocular Lens (IOL) in Cataractous Eyes
This is a Multi-center, single-arm and non-masked study whereby patients undergoing routine cataract surgery be implanted with a hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC (model POD T 49P).
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- PHY2107 (NCT05255029)
- Testing
- POD T 49P implantation experimental
- Where
- 4 sites in Japan
- Volunteers
- 42 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract, Presbyopia
Single-center, Double-arm, Prospective Clinical Trial to Compare Visual Performance of Non-diffractive Extended Vision and Neutral Aspheric Monofocal Intraocular Lenses
The purpose of this study is to compare the binocular distance, intermediate, and near visual acuity of the Alcon Vivity and Bausch \& Lomb enVista IOLs.
- Trial name
- NCT04591054
- Testing
- Extended Vision IOL, Neutral Aspheric Monofocal IOL
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Milton S. Hershey Medical Center
Amblyopia, Anisometropia
Dichoptic Virtual Reality Therapy for Amblyopia in Adults
This was a randomized, masked, controlled study of the effect of a virtual reality, binocular, 3-dimensional video game on visual acuity and stereopsis in adult patients with amblyopia.
- Conditions
- Amblyopia, Anisometropia, Strabismus
- Trial name
- NCT02246556
- Testing
- Dichoptic therapy, Patching therapy, Dioptic (non-dichoptic) therapy
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of California, San Francisco
Myopia, Refractive Error
A Comparison of Two Color Contact Lenses in Habitual Clear Contact Lens Wearers
The purpose of this study was to evaluate overall satisfaction with AIR OPTIX® COLORS as compared to FRESHLOOK® COLORBLENDS contact lenses.
- Trial name
- NCT01782482
- Testing
- Lotrafilcon B contact lens with color, Phemfilcon A contact lens with color
- Volunteers
- 574 people
- Sponsor
- Alcon Research
Myopia
LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear
This study is to evaluate the performance of the LSH (mangofilcon A) silicone hydrogel soft contact lenses when used as a daily wear contact lens for the correction of myopia.
- Trial name
- NCT01735045
- Testing
- Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens, Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens
- Where
- 5 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Szabocsik and Associates, Inc.
Myopia, Astigmatism
Wavelight Plus Sightmap-LASIK vs. Wavefront-Optimized-LASIK
The goal of this clinical trial is to learn if the wavelight plus Sightmap (WLP) method or the wavefront-optimized (WFO) method for calculating LASIK customization treatment gives better vision, better satisfaction, and fewer…
- Trial name
- NCT07855094
- Testing
- LASIK calculated ablation using Wavefront-Optimized, wavelight plus Sightmap (WLP) Guided LASIK calculated
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- 59th Medical Wing
Amblyopia
Treating Amblyopia With CureSight
Patients with visual acuity and ocular characteristics outside the Novasight FDA multi-center study are to perform the same Curesight procedures- including M\&S EVA or eETDRS patched acuity, stereo and then utilize the Curesight…
- Trial name
- ABCDCS (NCT06165705)
- Testing
- CureSight
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Alaska Blind Child Discovery
Myopia
Comparison of Two Daily Disposable Contact Lenses Over 1-week of Wear
This is a one week 2x2 crossover study comparing delefilcon A with etafilcon A, with a primary hypothesis of comparing the handling of each lens.
- Trial name
- NCT01669629
- Testing
- delefilcon A, etafilcon A
- Where
- 10 sites in United States
- Volunteers
- 183 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
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