Clinical trials: Eye--Refractive Errors
Myopia
Preservative-free Topical Anesthetics for Post-PRK Pain
The goal of this interventional comparative study is to assess the efficacy and safety of a novel regimen of preservative-free unit-dose topical anesthetics for controlling early postoperative pain following single-step…
- Trial name
- NCT05733741
- Testing
- Preservative-free Benoxinate hydrochloride 0.4% (Benoxidia unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt), Preservative-free Sodium hyaluronate 0.2% (Polyfresh unit-dose vials [UD], Orchidia pharmaceutical Ind., Egypt).
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myopia
Long Term Effects of Multifocal Orthokeratology on Corneal and Choroidal Structures in Healthy Subjects With Myopia- A Pilot Study
Orthokeratology has the benefit for slowing down myopia progression and enabling unaided vision during the day. To investigate proposed possible changes of conventional and multifocal orthokeratology in the cornea and choroid…
- Trial name
- NCT02700295
- Testing
- Orthokeratology lens
- Where
- Austria
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Myopia
Clinical Comparison of Two Soft Contact Lenses
This study was designed to gather short-term clinical performance data for 2 soft contact lenses.
- Trial name
- NCT06251154
- Testing
- Lens 1, Lens 2
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- CooperVision, Inc.
Presbyopia
Clinical Validation Study of Comfilcon A Multifocal Toric Contact Lenses
This is a study to evaluate the clinical performance and subjective acceptance of an investigational contact lens (test), compared to a marketed lens (control) in an in-office setting.
- Trial name
- NCT03417557
- Testing
- Comfilcon A lens (test), Omafilcon B lens (control)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- CooperVision, Inc.
Myopia Progression, Myopia
Inhibition of Myopia Progression With Optical Devices
This observational study aims to determine whether optical devices designed to slow myopia progression and/or environmental factors can prevent myopia progression in the pediatric and adolescent myopic population.
- Conditions
- Myopia Progression, Myopia, Myopia, Child Myopia Progression
- Trial name
- NCT07698977
- Testing
- Wearing myopia-control D.I.M.S. glasses while awake, DIMS (Defocus Incorporated Multiple Segments) lenses
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Refractive Error, Myopia
A Comparison of Two Daily Disposable Contact Lenses
This study seeks to evaluate the clinical performance of a new CE marked daily disposable contact lens that contains a wetting agent to a recently improved daily disposable contact lens.
- Trial name
- NCT00634101
- Testing
- nelfilcon A, narafilcon A
- Where
- 20 sites in United Kingdom
- Volunteers
- 129 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Cataracts
AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0] in Japan
The purpose of this study is to evaluate safety and effectiveness of AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0] in Japanese cataract patients.
- Trial name
- NCT01605877
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0]
- Where
- 2 sites in Japan
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Clinical Evaluation of WaveLight Plus LASIK
This study is a single-site, single-arm, prospective, observational study of subject satisfaction, quality of vision, and quality of life after bilateral LASIK surgery. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07127757
- Testing
- Wavelight Plus LASIK
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Laser Defined Vision
Myopia Progression, Axial Length, Eye
Low Dose Atropine Eye Drops in Myopic Egyptian Children
Previous Studies reported that low concentration atropine eye drops may be effective in increasing the choroidal blood flow and thickness and this slows myopia progression.
- Conditions
- Myopia Progression, Axial Length, Eye, Sclera Thickness
- Trial name
- LAMP (NCT06265454)
- Testing
- low dose atropine eye drops
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Myopia
To Evaluate the Effectiveness of New Specially Designed Fitlens Soft Lens.
Myopia is a common disorder, affecting approximately one-third of the US population and over 90% of the population in some East Asian countries.
- Trial name
- NCT05433792
- Testing
- Myolens CN (Central-Near) soft contact lens, MiSight® soft contact lens
- Where
- Israel
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Fitlens Ltd.
Refractive Errors
Safety and Effectiveness of the Qualis Contact Lens
Three-month, open-label, bilateral, parallel group, randomized, daily wear contact lens dispensing study.
- Trial name
- NCT04295499
- Testing
- soft (hydrophilic) contact lens
- Where
- 3 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Unicon Optical Co. Ltd.
Myopia
Efficacy and Safety of the New Defocus Spectacle Lens in Preventing Progression of Myopia
The clinical effects of new technical spectacles with refractive correction function are mixed. A randomised trial is designed to compare the effects of new defocusing spectacle lenses and traditional aspheric spectacle lenses on…
- Trial name
- NCT05740904
- Testing
- New defocus spectacle lenses, Convenional aspheric single-vision spectacle lenses
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Refractive Errors, Vision Disorders
Handheld Device Compared With a Standard Eye Care Diagnostic Device in Measuring Ophthalmic Refraction
This study is exploratory and examines whether the best-corrected visual acuities (BCVA's) from trial frames created with the refraction results obtained from a novel handheld optical device yields results similar to the…
- Trial name
- NCT04693247
- Testing
- EQ103
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- EyeQue Corp.
Myopia, Hyperopia
The Effect of Masking on Subjective Results During Daily Disposable Contact Lens Studies
The purpose of this study is to explore the effect of masking on subjective ratings for two daily disposable contact lenses.
- Trial name
- ARGON (NCT01155726)
- Testing
- Nelfilcon A contact lens, Nelfilcon A contact lens with comfort additive (DACP), unmasked, Nelfilcon A contact lens with comfort additive (DACP), masked
- Where
- Canada
- Volunteers
- 134 people
- Sponsor
- CIBA VISION
Axial Myopia, Refractive Errors
Evaluation of Progression of Myopia in Children Treated With Vitamin B2 and Outdoor Sunlight Exposure
The investigators plan on using riboflavin (a Vitamin that can easily be taken orally each day) and having the children involved in the study play outside (where there is UV light created by the sun) in order to prevent the eye…
- Trial name
- NCT03552016
- Testing
- Oral Riboflavin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Presbyopia
Compound to Control Presbyopia Symptoms
Low dose compose to control presbyopia symptoms
- Trial name
- NCT05006898
- Testing
- PBO to control presbyopia symptoms
- Where
- Mexico
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Optall Vision
Refractive Error
Proof of Concept Study for First-Sight Refractive Error Correction: Direct Comparison to Manifest Refraction and Autorefraction Results
Proof of concept study is to compare the best corrected visual acuity obtained via First-Sight lenses with the clinical "gold standard" of manifest refraction and autorefraction.
- Trial name
- NCT01342393
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cataract, Refractive Error
A Study of Interventions to Reduce Disability From Visual Loss in Nursing Home Residents
The purpose of this clinical trial is to determine if interventions within the nursing home to restore vision, or cope with visual loss, in residents with visual impairment result in improvement or less decline in mobility…
- Conditions
- Cataract, Refractive Error, Low Vision
- Trial name
- NCT00348621
- Testing
- Visual impairment intervention program
- Where
- United States
- Volunteers
- 2,544 people
- Sponsor
- Johns Hopkins University
Myopia, Hyperopia
A Clinical Comparison of Proclear® 1 Day Multifocal and Clariti® 1 Day Multifocal 3 Add
The aim of this study is to compare the overall lens satisfaction between two soft multifocal contact lenses.
- Conditions
- Myopia, Hyperopia, Presbyopia
- Trial name
- NCT06869044
- Testing
- omafilcon A lens, Low ADD power somofilcon A lens, Medium ADD power somofilcon A lens
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- CooperVision International Limited (CVIL)
Myopia, Hypermetropia
Anesthetic Impregnated Bandage Soft Contact Lens (BSCL) in Pain Management After Photorefractive Keratectomy (PRK)
Compared to laser-assisted in situ keratomileusis (LASIK), Photorefractive Keratectomy (PRK) is associated with more discomfort and requires more downtime.
- Conditions
- Myopia, Hypermetropia, Refractive Errors, Astigmatism
- Trial name
- NCT04283331
- Testing
- Proparacaine Ophthalmic
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beeran Meghpara, MD
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