Clinical trials: Eye--Refractive Errors
Myopia
Dispensing Overnight Study in Lenses
The purpose of the study is to evaluate the fit and performance of an investigational soft contact lens in comparison with a currently marketed lens.
- Trial name
- NCT00349856
- Testing
- Biofinity
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Myopia
Prospective Evaluation of Radial Keratotomy (PERK) Study
To determine whether radial keratotomy is effective in reducing myopia. To detect complications of the surgery. To discover patient characteristics and surgical factors affecting the results.
- Trial name
- NCT00000129
- Testing
- Radial Keratotomy
- Sponsor
- National Eye Institute (NEI)
Cataract, Lens Opacity
Comparison of Clinical Outcomes POD L GF vs POD F GF (PHY1707)
Prospective, randomised, controlled, single-surgeon, single-center clinical study to compare the clinical outcomes of two trifocal IOLs differing in the dominance of additional power.
- Conditions
- Cataract, Lens Opacity, Presbyopia
- Trial name
- NCT03688399
- Testing
- IOL implantation experimental, IOL implantation comparator
- Where
- Hungary
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Beaver-Visitec International, Inc.
Myopia, Visual Diet
Longitudinal Measurements of Visual Diet in Children
Myopia is a leading cause of visual impairment worldwide, with prevalence rising rapidly among children. Growing evidence suggests that environmental and behavioral factors play a dominant role in ocular growth; however, current…
- Conditions
- Myopia, Visual Diet, Pupil, Viewing Distance
- Trial name
- VEET (NCT07642999)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- State University of New York College of Optometry
Myopia
Characterization of the Corneal Biomechanics of Patients Treated by Corneal Lenticule Extraction for Advanced Refractive Correction (CLEAR) to Correct Myopia
This study aims to perform biomechanical tests on extracted CLEAR lenticles that are routinely discarded after surgery. The investigators also aim to perform Brillouin microscopy to get an in-vivo assessment of the patient's…
- Trial name
- CLEAR Biomech (NCT04817592)
- Testing
- Corneal lenticule extraction for advanced refractive correction (CLEAR)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bern
Near Vision
Pharmacological Treatment of Presbyopia
In this clinical trial, a total of 75 presbyopic patients in the age range of 40 to 60 years old will be participated. The right eyes of 45 patients will be treated by Biocarpine® and they will be considered as the case group…
- Trial name
- NCT05564832
- Testing
- Pilocarpine 1.25% Eye drop
- Where
- Iran
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Refractive Error
Proof of Concept Study for First-Sight Refractive Error Correction: Direct Comparison to Manifest Refraction and Autorefraction Results
Proof of concept study is to compare the best corrected visual acuity obtained via First-Sight lenses with the clinical "gold standard" of manifest refraction and autorefraction.
- Trial name
- NCT01342393
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Presbyopia
Comparison of Three Soft Bifocal Contact Lenses
The primary purpose of the study is to compare the performance of three soft bifocal contact lenses in terms of the vision provided by the lenses.
- Trial name
- NCT00808340
- Testing
- balafilcon A, senofilcon A production, senofilcon A test
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Vision Loss
First-Sight Refractive Error Correction in the Developing World
The aim of this study is to test the efficacy of the First-Sight refractive kit designed to provide refractive correction of simple hyperopia, myopia and astigmatism with autorefraction.
- Trial name
- NCT01598818
- Where
- 2 sites in United States, Haiti
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Presbyopia
A Prospective Study to Evaluate the Raindrop Near Vision Inlay With Mitomycin C
The objective of this study is to evaluate the Raindrop® Near Vision Inlay for the improvement of near vision in presbyopes treated with low dose, short duration Mitomycin C (MMC) during surgery and an extended low dose steroid…
- Trial name
- NCT03242317
- Testing
- Mitomycin C, Raindrop Near Vision Inlay
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Fichte, Endl & Elmer Eyecare
Myopia, Hyperopia
Subjective Comparison of Pre-Lens Tear Film Stability With Daily Disposable Contact Lenses
The purpose of this study was to compare three CE-marked daily disposable contact lenses for tear film stability as measured by pre-lens non-invasive keratograph break up time (PL NIK-BUT).
- Conditions
- Myopia, Hyperopia, Refractive Error
- Trial name
- NCT01839318
- Testing
- Nelfilcon A contact lenses, Omafilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 30 people
- Sponsor
- Alcon Research
Myopia
Efficacy and Safety of Defocusing Frame Glasses With Artificial Intelligence in Controlling Myopia Progression
Background: Myopia refers to the pathological state in which the external parallel light enters the eye and focuses in front of the retina, resulting in the inability to clearly image on the retina.
- Trial name
- NCT05532774
- Testing
- AI defocusing frame glasses
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Shanghai Eye Disease Prevention and Treatment Center
Myopia, Outdoor Activity
Vision Care Intervention for Lower Grade School Children in Taiwan
The purpose of this study is making use of school policy- recess outside classroom (ROC7-11) for increasing the time spent outdoor during recess and encouraging children spent time outdoor up to 11 hours in each week to…
- Conditions
- Myopia, Outdoor Activity, Policy of Recess Outside Classroom
- Trial name
- NCT02082743
- Testing
- Outdoor activity in recess time
- Where
- Taiwan
- Volunteers
- 1,020 people
- Sponsor
- Chang Gung Memorial Hospital
Corneal Astigmatism
Limbal Relaxing Incisions Versus Paired 4 mm Clear Corneal Incisions on Steep Meridian During Phacoemulsification
The goal of this is prospective, computer based randomized clinical trial is to compare the efficacy of reduction of the pre-existing corneal astigmatism at the time of cataract surgery in patients admitted in sohag university…
- Trial name
- LRI-CCI (NCT05593263)
- Testing
- surgical correction of astigmatism with cataract
- Volunteers
- 120 people
- Sponsor
- Sohag University
Myopia
MyopiaX Treatment for the Reduction of Myopia Progression in Children and Adolescents: Safety and Efficacy Investigation
The purpose of this trial is to investigate the safety and efficacy of MyopiaX - a digital treatment intended to slow the progression of myopia in children and adolescents.
- Trial name
- MyopiaX-1 (NCT04967287)
- Testing
- MyopiaX, Myopia control spectacles
- Where
- 10 sites in Germany, Netherlands and 3 more
- Volunteers
- 124 people
- Sponsor
- Dopavision GmbH
Cataract
Rotational Stability of the TECNIS Eyhance Toric
Evaluation of the rotational stability of a new toric intraocular lens (IOL), the TECNIS Eyhance toric II.
- Trial name
- NCT05126368
- Testing
- Cataract surgery
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Vienna Institute for Research in Ocular Surgery
Myopia
Myopia Progression Trial With Novel Myopia Control Design Spectacle Lenses
This is a mono-center, randomized, double-masked, cross-over study to evaluate rate of myopia progression with novel designed myopia control lens (test) compared to SVL (control).
- Trial name
- NCT04048148
- Testing
- Novel designed myopia control spectacle lenses
- Where
- Vietnam
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Brien Holden Vision Institute
Presbyopia
Safety & Efficacy of the Laser Scleral Microporation Procedure (Philippines)
A minimally invasive procedure for treating presbyopia is being evaluated to determine if there is improvement in near and intermediate vision after treatment.
- Trial name
- NCT04151550
- Testing
- Bilateral Laser Scleral Microporation procedure
- Where
- Philippines
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ACE Vision Group, Inc.
Refractive Error
Formula Identification (FID) 114657 in Contact Lens Wearers
The purpose of this study is to evaluate the thickness of the pre-lens tear lipid layer after 2 hours of lens wear with use of FID 114657 compared to saline control.
- Trial name
- NCT02293538
- Testing
- FID 114657 eye drops (10 ml), Saline control eye drops (15 ml), Habitual contact lenses
- Volunteers
- 234 people
- Sponsor
- Alcon Research
Presbyopia
A Safety, Efficacy and Pharmacokinetic Study of AGN-199201 and AGN-190584 in Patients With Presbyopia
This is a safety, efficacy and pharmacokinetics study of the fixed combination of AGN-199201 and AGN-190584 in participants with presbyopia (inability to focus on items close-up).
- Trial name
- NCT02780115
- Testing
- AGN-199201 ophthalmic solution, AGN-190584 ophthalmic solution, AGN-199201 Vehicle
- Where
- 25 sites in United States
- Volunteers
- 151 people
- Sponsor
- Allergan
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