Clinical trials: FACE
Dental Pain
A Study of ARRY-371797 in Subjects Undergoing Third Molar Extraction
This is a Phase 2 study designed to test the ability of investigational study drug ARRY-371797 to reduce pain in a postoperative pain model (third molar extraction), and to further evaluate the drug's safety.
- Trial name
- NCT00663767
- Testing
- ARRY-371797, p38 inhibitor; oral, Celecoxib, COX-2 inhibitor; oral
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Pfizer
Face and Neck Wrinkles, Texture, Pigmentation
Lutronic Infini and LaseMD Systems in Combination Treatment
This is a prospective, multi-site, non-randomized study evaluating the safety and effectiveness of the Infini and LaseMD Systems for combination treatment in wrinkles, texture, and pigmentation of the face and/or neck.
- Trial name
- NCT03409965
- Testing
- Lutronic Infini System, Lutronic LaseMD System
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Skin Care
Assessment of the Cosmetic Benefit of a Skin Cream in Healthy Females With Mild to Advanced Photo-damaged Facial Skin Who Have Undergone a Glycolic Acid Facial Peel Procedure
To evaluate the local tolerance and cosmetic efficacy of a topical skin care formulation in healthy female participants with mild to advanced photo-damaged facial skin who have undergone a 70% Glycolic Acid facial peel procedure.
- Trial name
- NCT03197883
- Testing
- Test Product, Cleanser, Sunscreen
- Where
- Brazil
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Actinic Keratosis (AK)
A Study to Evaluate Two Concentrations of DFD-07 Cream, in Subjects With Actinic Keratosis (AK) of the Face and/or Scalp Over a 12-week Treatment Period
Once or twice daily 12 week treatment in patients with Actinic Keratosis randomized to treatment in one of four arms.
- Trial name
- NCT03116698
- Testing
- Low dose DFD07 once daily, High dose DFD07 once daily, High dose DFD07 twice daily
- Where
- 20 sites in United States
- Volunteers
- 240 people
- Sponsor
- Dr. Reddy's Laboratories Limited
Dermal Filler, Hyaluronic Acid
The Evaluation of the Safety and Effectiveness of ANIMERS Chiara LA and JUVÉDERM VOLUMA® for Aging Mid-Face
This study is to evaluate the safety and effectiveness for the correction of aging mid-face of treatment group compared with the active control group.
- Conditions
- Dermal Filler, Hyaluronic Acid, Lidocaine, Aging Mid-Face
- Trial name
- NCT04622085
- Testing
- ANIMERS Chiara LA, JUVÉDERM VOLUMA®
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SciVision Biotech Inc.
Mild to Moderate Acne
Evaluation of the Safety and Efficacy of an Acne Treatment Device
A 50-patient study in which 400 microamps of direct current was applied 3 days per week. All tolerability, safety and efficacy endpoints were met.
- Trial name
- NCT06420804
- Testing
- ZIIP Acne Treatment Device
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- ZIIP Beauty
Wrinkle
Evaluation of Safety and Efficacy of the BTL-785F Device for Non-invasive Facial Remodeling
This study will evaluate the clinical safety and the performance of the BTL-785F system equipped with the BTL-785-7 applicator for non-invasive facial remodeling.
- Trial name
- NCT05525026
- Testing
- BTL-785-7
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- BTL Industries Ltd.
Correction of Facial Wrinkles/Folds, Facial Volume Enhancement
Post-Market Clinical Follow-up Performance and Safety Study of Etermis 3 and 4 in the Face
To confirm the clinical performance of Etermis 3 and Etermis 4 based on the blinded investigator´s assessments on the respective Merz Aesthetics Scales from day 0 (D0) pre-injection to month 6/7 (depending on touch up) visit for…
- Trial name
- POMET (NCT04210258)
- Testing
- Etermis 3, Etermis 4
- Where
- 6 sites in Germany
- Volunteers
- 154 people
- Sponsor
- Merz Pharmaceuticals GmbH
Facial Rhytides, Skin Folds, Loss of Volume and Skin Quality
A Study to Evaluate Participant Satisfaction With Facial Appearance Overall and the Aesthetic and Psychosocial Impact of Combined Facial Treatment
The objective of this study is to quantify the psychological and emotional impact of comprehensive aesthetic treatment with a portfolio of Allergan products by measuring the change in participant's satisfaction with facial…
- Trial name
- NCT03712449
- Testing
- JUVÉDERM®, BOTOX Cosmetic®, BELKYRA®
- Where
- 7 sites in Canada
- Volunteers
- 59 people
- Sponsor
- Allergan
Heart Rate, Heart Rate Variability
Contactless Measurement of Heart Rate, Heart Rate Variability and Breathing Rate Using Remote Photoplethysmography
The purpose of this study it to evaluate the accuracy of heart rate, heart rate variability and breathing rate measurement with the use of Shen.AI Vitals software developed by MX Labs.
- Conditions
- Heart Rate, Heart Rate Variability, Respiratory Rate
- Trial name
- NCT05889832
- Testing
- measurement of physiological parameters wih Shen.AI Vitals software on various camera-equipped devices (smartphones, tablets, laptops)
- Where
- Poland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- SHEN.AI spółka z ograniczoną odpowiedzialnością oddział w Polsce
Facial Contouring
A Study to Evaluate Patient Satisfaction With the Overall Face and Neck Appearance After Combined Treatment of OnabotulinumtoxinA, JUVÉDERM® Products, KYBELLA, CoolSculpting Elite and SkinMedica Products
A study to evaluate overall participant satisfaction of face and neck appearance after treatment with onabotulinumtoxinA, JUVÉDERM® products, KYBELLA, CoolSculpting Elite, and select SkinMedica products in a diverse population.
- Trial name
- US Harmony (NCT06783621)
- Testing
- OnabotulinumtoxinA, JUVÉDERM, CoolSculpting Elite System
- Where
- 10 sites in United States
- Volunteers
- 130 people
- Sponsor
- AbbVie
Healthy Subjects
Evaluate Onset of Action of a Fast Release Aspirin
To compare the safety and efficacy (onset, duration of relief and overall efficacy) of a single dose of a fast release formulation of aspirin 1000 mg compared to acetaminophen 1000 mg and placebo for relief of pain following…
- Trial name
- TAROT compare (NCT01420094)
- Testing
- Acetylsalicyclic acid (Fast release Aspirin, BAY1019036), Acetaminophen (Tylenol extra strength)
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- Bayer
Acne Vulgaris, Acne
Safety, Tolerability, and Immunogenicity of ORI-A-ce001 for the Treatment of Acne Vulgaris
Acne vulgaris, or acne, is one of the most prevalent diseases worldwide, with skin conditions being one of the top causes of years lived with disability and non-fatal disease burden.
- Trial name
- OREA (NCT05131373)
- Testing
- ORG101 - Experimental 1
- Where
- 6 sites in Germany
- Volunteers
- 38 people
- Sponsor
- Sanofi Pasteur, a Sanofi Company
Trigeminal Neuralgia
A Phase IIa Withdrawal Study of CNV1014802 in Patients With Trigeminal Neuralgia
This is a double-blind, randomized withdrawal study comparing CNV1014802 with placebo in patients with trigeminal neuralgia who have successfully responded to CNV1014802 in an initial open-label phase.
- Trial name
- NCT01540630
- Testing
- CNV1014802
- Where
- United Kingdom
- Volunteers
- 67 people
- Sponsor
- Biogen
Central Sleep Apnea, Heart Failure
French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS, AirCurve 10CS): Predictive Factors of Poor Compliance (FACE)
The purpose of this study is to determine the predictive factors of poor compliance to sleep disordered breathing therapy in chronic heart failure patients treated for central sleep apnea.
- Trial name
- FACE (NCT02356367)
- Testing
- telemonitoring
- Where
- 3 sites in France
- Sponsor
- ResMed
Laxity; Skin
Pivotal Study to Evaluate the Safety and Efficacy of a Micro-coring Device Treating Moderate to Severe Facial Wrinkles
Study evaluating the safety and efficacy of a micro-coring device for the treatment of moderate to severe cheek wrinkles.
- Trial name
- NCT03573271
- Testing
- MCD
- Where
- 5 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cytrellis Biosystems, Inc.
Melasma
Anti-pigmenting Effect of a Routine of Facial Products in Subjects With Melasma
This 6 month, comparative study assesses the benefit of a dermocosmetic regimen (Serum B3 + B3 retinol night cream) for 6 months compared to hydroquinone 4% (the gold standard in hyperpigmentation) followed by the dermocosmetic…
- Trial name
- NCT06516224
- Testing
- Liftactiv® B3 Serum, Liftactiv® B3 retinol night cream, Sunscreen UVAage® Inter SPF 50+
- Where
- Brazil
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cosmetique Active International
Photodamaged Skin
A Study to Assess the Effects of an Oral Dietary Supplement on Overall Facial Appearance Among Healthy Adult Women With Existing Skin Damage From Sun Exposure
The study hypothesis is that Imedeen will show effects on skin health, when compared to placebo over a 6 month intervention period with respect to changes in skin appearance, skin density, moisture, and in fine lines and wrinkles.
- Trial name
- NCT01787461
- Testing
- Imedeen
- Where
- 4 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Pfizer
Skin Laxity (Submental and Neck), Skin Lifting and Tightening
Safety and Efficacy of a 2,910 nm Fractional Ablative Fiber Laser (UltraClear®) for Improvements of Skin Laxity and Lifting of the Lower Face, Submental, and Neck Treatment Areas
This study evaluates the safety and effectiveness of the UltraClear® 2,910 nm fractional ablative fiber laser for improving skin laxity and tissue lifting in the lower face, submental, and neck areas.
- Trial name
- UC 29-2026 (NCT07759817)
- Testing
- 2910 nm fiber laser (UltraClear®)
- Where
- 2 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- FA Corporation
Pain
Acetaminophen/Naproxen Sodium Dose Ranging Study
Study assessing the relative efficacy of five strengths of a fixed combination of acetaminophen and naproxen sodium is being investigated to help inform selection of dose(s) for further development and to evaluate the safety of a…
- Trial name
- NCT04447040
- Testing
- Acetaminophen/naproxen sodium Dose A, Acetaminophen/naproxen sodium Dose B, Acetaminophen/naproxen sodium Dose C
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- Johnson & Johnson Consumer Inc., McNeil Consumer Healthcare Division